David K. Ann

23.7k citations

171 papers · 8.3k indexed · 3 hit papers · h-index 52

Impact in

Cancer Research top 0.5%
- Cancer, Hypoxia, and Metabolism
- Cancer-related molecular mechanisms research
- Cancer, Lipids, and Metabolism
Molecular Biology top 1%
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Ubiquitin and proteasome pathways

Papers in

Cancer Research 40
- Cancer, Hypoxia, and Metabolism 22
Molecular Biology 123
- DNA Repair Mechanisms 16
- Ubiquitin and proteasome pathways 15
- RNA modifications and cancer 13
- Genomics and Chromatin Dynamics 12
- Epigenetics and DNA Methylation 11

Co-authors: Yun Yen H. Helen Lin Ching‐Ying Kuo Hsing-Jien Kung Don M. Carlson Jing‐hsiung James Ou Donna Sir Kwang‐Jin Kim
Journals: Journal of Biological Chemistry (30 papers)American Journal of Physiology-Cell Physiology (7 papers)Autophagy (6 papers)Cancer Research (6 papers)American Journal of Respiratory Cell and Molecular Biology (6 papers)
Partner nations: United States Taiwan China

In The Last Decade

David K. Ann

168 papers receiving 8.2k citations

Hit Papers

align trajectories log scale

Arginine Signaling and Cancer Metabolism 2021 · 173 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2021 Cancers
2019 Cancer Immunology Research
2017 Cell Metabolism

Peers

Countries citing papers authored by David K. Ann

Since Specialization

Citations

This map shows the geographic impact of David K. Ann's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David K. Ann with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David K. Ann more than expected).

Fields of papers citing papers by David K. Ann

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David K. Ann. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David K. Ann. The network helps show where David K. Ann may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David K. Ann, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David K. Ann Line = papers co-authored together David K. Ann links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A Critical Role of Intracellular PD-L1 in Promoting Ovarian Cancer Progression Cells ·Rui Huang, Brad J. Nakamura, 農士黒石, Yijia Li, Antons Martincuks, Mattia Magi, Wafaa Zibar, David K. Ann, Lorna Rodrı́guez-Rodrı́guez, Hua Yu	2025	0
2	Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination Cell Reports ·Yi-Chang Wang, 郑晓莉, Meliina Rantakaulio, Yi‐Hsuan Chen, Wei‐Kai Chen, Robert Mrvcic, Yue Qi, Long Gu, Linda H. Malkas, Angelo Taglialatela, Hsing‐Jien Kung, George‐Lucian Moldovan, Alberto Ciccia, Jeremy M. Stark, David K. Ann	2023	4
3	Ncoa2 Promotes CD8+ T cell–Mediated Antitumor Immunity by Stimulating T-cell Activation via Upregulation of PGC-1α Critical for Mitochondrial Function Cancer Immunology Research ·Xiancai Zhong, Hongmin Wu, Ching Ouyang, D.B. Goncharov, 加藤光夫, Yi-Chang Wang, David K. Ann, Yousang Gwack, Weirong Shang, Zuoming Sun	2023	15
4	Obesity promotes radioresistance through SERPINE1-mediated aggressiveness and DNA repair of triple-negative breast cancer Cell Death and Disease ·Tonya M Carter, 由規子恩智, David K. Ann, Jenny Ling‐Yu Chen, Ching‐Ying Kuo	2023	30
5	Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids Cell Reports ·Yijia Li, Johannes F. Fahrmann, Maryam Aftabizadeh, Qianqian Zhao, S. C. Tripathi, Chunyan Zhang, Yuan Yuan, David K. Ann, Samir Hanash, Hua Yu	2022	78
6	Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3 Cell Reports ·Yumei Li, 浩美増渕, Shu Feng, Yuji Ishida, Tsu-Pei Chiu, Takeshi Saito, Antonia Putzger, David K. Ann, Jing‐hsiung James Ou	2022	31
7	Epigenetic Dysregulation of KCNK9 Imprinting and Triple-Negative Breast Cancer Cancers ·David Skaar, Eric C. Dietze, Jackelyn A. Alva-Ornelas, David K. Ann, Dustin E. Schones, Terry Hyslop, Christopher Sistrunk, Carola M. Zalles, J. van Steelant, Gus Bas, Ж Түмэнхүслэн, عاطفه رنجبر دارستانی, Michael N. Gould, Randy L. Jirtle, Victoria L. Seewaldt	2021	4
8	Potent antitumor effects of cell-penetrating peptides targeting STAT3 axis JCI Insight ·Maryam Aftabizadeh, Yijia Li, Qianqian Zhao, Chunyan Zhang, Margit Hermundsgård, Jieun Song, Toshikage Nagao, Christoph Lahtz, Marwan Fakih, David K. Ann, Hua Yu, Andreas Herrmann	2021	15
9	IL15 Enhances CAR-T Cell Antitumor Activity by Reducing mTORC1 Activity and Preserving Their Stem Cell Memory Phenotype Cancer Immunology Research ·Darya Alizadeh, Robyn A. Wong, Xin Yang, Dongrui Wang, Joseph R. Pecoraro, Cheng-Fu Kuo, Brenda Aguilar, Yue Qi, David K. Ann, Renate Starr, Ryan Urak, Xiuli Wang, Stephen J. Forman, Christine E. Brown Hit paper breakdown →	2019	324
10	Metabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells Cancer Research ·Chun-Ting Cheng, Ching‐Ying Kuo, Ching Ouyang, Chien‐Feng Li, Yiyin Chung, David C. Chan, Hsing-Jien Kung, David K. Ann	2016	54
11	Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation Nature Cell Biology ·Min Pan, Michael A. Reid, Xazmin H. Lowman, Rajan P. Kulkarni, Thai Q. Tran, Xiaojing Liu, Ying Yang, Jenny E. Hernandez‐Davies, Παναγιώτης Γαζής, Haiqing Li, Willy Hugo, Chunying Song, Xiangdong Xu, Dustin E. Schones, David K. Ann, Viviana Gradinaru, Roger S. Lo, Jason W. Locasale, Mei Kong	2016	276
12	Frequent Overexpression of HMGA2 in Human Atypical Teratoid/Rhabdoid Tumor and Its Correlation with let-7a3/let-7b miRNA Clinical Cancer Research ·Keqiang Zhang, Hanlin Gao, Xiwei Wu, Jinhui Wang, Wendi Zhou, Guihua Sun, Jinghan Wang, Yafan Wang, Bing Mu, Charles C. Kim, Peiguo Chu, Donald Ming-Tak Ho, David K. Ann, Tai‐Tong Wong, Yun Yen	2014	32
13	TGFβ Induces “BRCAness” and Sensitivity to PARP Inhibition in Breast Cancer by Regulating DNA-Repair Genes Molecular Cancer Research ·Liang Liu, Weiying Zhou, Chun-Ting Cheng, Xiubao Ren, George Somlo, Miranda Fong, Andrew R. Chin, Hui Li, Yang Yu, Yang Xu, Sean Timothy Francis O’Connor, Timothy O’Connor, David K. Ann, Jeremy M. Stark, Shizhen Emily Wang	2014	55
14	Interactions Between β-Catenin and Transforming Growth Factor-β Signaling Pathways Mediate Epithelial-Mesenchymal Transition and Are Dependent on the Transcriptional Co-activator cAMP-response Element-binding Protein (CREB)-binding Protein (CBP) Journal of Biological Chemistry ·Beiyun Zhou, Yixin Liu, Michaël Kahn, David K. Ann, Arum Han, Hongjun Wang, Cu Nguyen, Per Flodby, Qian Zhong, Manda S. Krishnaveni, Janice M. Liebler, Parviz Minoo, Edward D. Crandall, Zea Borok	2012	221
15	Overexpression of HMGA2 Promotes Metastasis and Impacts Survival of Colorectal Cancers Clinical Cancer Research ·Xiaochen Wang, Xiyong Liu, RAMESH CHANDRAN, Lirong Chen, Lily Lai, H. Helen Lin, Shuya Hu, Lifang Yao, Jiaping Peng, Sofia Loera, Lijun Xue, Bingsen Zhou, Lun Zhou, Shu Zheng, Peiguo Chu, Suzhan Zhang, David K. Ann, Yun Yen	2011	151
16	p53R2 Inhibits the Proliferation of Human Cancer Cells in Association with Cell-Cycle Arrest Molecular Cancer Therapeutics ·Keqiang Zhang, Jun Wu, Xiwei Wu, Xiaochen Wang, Yan Wang, Ning Zhou, Mei-Ling Kuo, Xiyong Liu, Bingsen Zhou, Lufen Chang, David K. Ann, Yun Yen	2011	43
17	Suppression of Nonhomologous End Joining Repair by Overexpression of HMGA2 Cancer Research ·Carmel Peri, Nan Zuo-mi, Shih-Ya Wang, H. Helen Lin, Clay C. C. Wang, Yun Yen, Benjamin P.C. Chen, David J. Chen, David K. Ann	2009	68
18	SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome Molecular Cancer Therapeutics ·Xuefei Cao, Григорий Никифорович Дончевский, Xu Li, H. Helen Lin, Yuan Chen, Hsiu-Ming Shih, David K. Ann	2008	17
19	Novel Roles for Protein Kinase C;-dependent Signaling Pathways in Acute Hypoxic Stress-induced Autophagy Journal of Biological Chemistry ·Huan Jun-Hua, H. Helen Lin, Kwang‐Jin Kim, Anning Lin, Henry Jay Forman, David K. Ann	2008	42
20	The helix-loop-helix proteins (salivary-specific cAMP response element-binding proteins) can modulate cAMP-inducible RP4 gene expression in salivary cells Journal of Biological Chemistry ·Jiasong Wu, Diah Sapitri, David K. Ann	1993	15

About David K. Ann

David K. Ann is a scholar working on Cancer Research, Molecular Biology, Oncology, Biotechnology and Physiology, having authored 171 papers that have together received 8.3k indexed citations. Recurring topics across this work include Cancer, Hypoxia, and Metabolism (22 papers), Autophagy in Disease and Therapy (17 papers), DNA Repair Mechanisms (16 papers), Ubiquitin and proteasome pathways (15 papers), RNA modifications and cancer (13 papers), Genomics and Chromatin Dynamics (12 papers), Cancer Research and Treatments (12 papers) and Epigenetics and DNA Methylation (11 papers). The work is most often cited by research in Cancer Research (2.0k citations), Molecular Biology (5.0k citations), Oncology (1.9k citations), Biotechnology (382 citations) and Biochemistry (311 citations). David K. Ann has collaborated with scholars based in United States, Taiwan and China. Frequent co-authors include Yun Yen, H. Helen Lin, Ching‐Ying Kuo, Hsing-Jien Kung, Don M. Carlson, Jing‐hsiung James Ou, Donna Sir, Kwang‐Jin Kim, Zea Borok and Edward D. Crandall. Their work appears in journals such as Journal of Biological Chemistry, American Journal of Physiology-Cell Physiology, Autophagy, Cancer Research and American Journal of Respiratory Cell and Molecular Biology.

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