Siegfried W. de Laat

10.4k total citations · 2 hit papers
165 papers, 9.0k citations indexed

About

Siegfried W. de Laat is a scholar working on Molecular Biology, Oncology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Siegfried W. de Laat has authored 165 papers receiving a total of 9.0k indexed citations (citations by other indexed papers that have themselves been cited), including 122 papers in Molecular Biology, 27 papers in Oncology and 22 papers in Cellular and Molecular Neuroscience. Recurrent topics in Siegfried W. de Laat's work include Lipid Membrane Structure and Behavior (23 papers), Ion channel regulation and function (17 papers) and Protein Kinase Regulation and GTPase Signaling (17 papers). Siegfried W. de Laat is often cited by papers focused on Lipid Membrane Structure and Behavior (23 papers), Ion channel regulation and function (17 papers) and Protein Kinase Regulation and GTPase Signaling (17 papers). Siegfried W. de Laat collaborates with scholars based in Netherlands, Israel and United States. Siegfried W. de Laat's co-authors include Wouter H. Moolenaar, Leon G.J. Tertoolen, Paul T. van der Saag, Christine L. Mummery, W. Kruijer, John G. Bluemink, Ben C. Tilly, Roger Y. Tsien, J. Boonstra and E.J.J. van Zoelen and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Siegfried W. de Laat

164 papers receiving 8.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts

1983 629 citations Wouter H. Moolenaar, Paul T. van der Saag et al. profile →
Growth factor-like action of phosphatidic acid

1986 464 citations Wouter H. Moolenaar, W. Kruijer et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Siegfried W. de Laat Netherlands	51	6.5k	1.3k	1.2k	1.1k	1.1k	165	9.0k
J. F. Whitfield Canada	50	5.5k 0.8×	825 0.7×	1.8k 1.5×	770 0.7×	1.2k 1.0×	303	9.0k
Christer Wernstedt Sweden	45	6.1k 0.9×	995 0.8×	1.5k 1.2×	865 0.8×	919 0.8×	85	9.5k
Michael J. Comb United States	47	8.6k 1.3×	1.2k 0.9×	1.6k 1.3×	2.1k 1.8×	856 0.8×	76	11.3k
Stephen P. Soltoff United States	43	5.8k 0.9×	1.1k 0.9×	1.7k 1.4×	981 0.9×	424 0.4×	73	8.8k
Ralph Bradshaw United States	58	5.9k 0.9×	1.5k 1.2×	1.4k 1.2×	3.1k 2.7×	623 0.6×	188	10.2k
Thomas Wieland Germany	55	6.5k 1.0×	1.2k 0.9×	657 0.6×	1.2k 1.1×	762 0.7×	253	10.2k
Hisashi Hidaka Japan	56	7.4k 1.1×	1.5k 1.2×	929 0.8×	2.2k 1.9×	636 0.6×	272	12.8k
Dianqing Wu United States	48	7.0k 1.1×	1.4k 1.1×	1.6k 1.4×	1.4k 1.2×	1.1k 1.0×	64	10.0k
Wei‐Jen Tang United States	54	8.5k 1.3×	1.6k 1.3×	1.1k 0.9×	1.7k 1.5×	1.5k 1.3×	144	11.0k
Marsha Rich Rosner United States	61	7.9k 1.2×	1.2k 1.0×	1.8k 1.5×	918 0.8×	794 0.7×	178	11.3k

Countries citing papers authored by Siegfried W. de Laat

Since Specialization

Citations

This map shows the geographic impact of Siegfried W. de Laat's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Siegfried W. de Laat with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Siegfried W. de Laat more than expected).

Fields of papers citing papers by Siegfried W. de Laat

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Siegfried W. de Laat. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Siegfried W. de Laat. The network helps show where Siegfried W. de Laat may publish in the future.

Co-authorship network of co-authors of Siegfried W. de Laat

This figure shows the co-authorship network connecting the top 25 collaborators of Siegfried W. de Laat. A scholar is included among the top collaborators of Siegfried W. de Laat based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Siegfried W. de Laat. Siegfried W. de Laat is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Brink, C.E. van den, et al.. (1997). Cell scattering of SK-N-MC neuroepithelioma cells in response to Ret and FGF receptor tyrosine kinase activation is correlated with sustained ERK2 activation. Oncogene. 14(10). 1147–1157. 35 indexed citations

Overvoorde, John, et al.. (1996). Expression of receptor protein-tyrosine phosphatase α mRNA and protein during mouse embryogenesis. Mechanisms of Development. 58(1-2). 89–101. 21 indexed citations

Joore, Jos, Johanna E. Speksnijder, W. Kruijer, et al.. (1996). Regulation of the zebrafish goosecoid promoter by mesoderm inducing factors and Xwnt1. Mechanisms of Development. 55(1). 3–18. 25 indexed citations

Gorter, Gertie, et al.. (1995). Relation between membrane fluidity and signal transduction in the human megakaryoblastic cell line MEG-01. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1236(1). 128–134. 13 indexed citations

Stolpe, Anja van de, Marcel Karperien, Clemens W.G.M. Löwik, et al.. (1993). Parathyroid hormone-related peptide as an endogenous inducer of parietal endoderm differentiation.. The Journal of Cell Biology. 120(1). 235–243. 92 indexed citations

Smit, Martine J., Rob Leurs, Leon G.J. Tertoolen, et al.. (1993). Extracellular ATP elevates cytoplasmatic free Ca2+ in HeLa cells by the interaction with a 5′-nucleotide receptor. European Journal of Pharmacology Molecular Pharmacology. 247(2). 223–226. 17 indexed citations

Hertog, Jeroen den, Rolf P. de Groot, Siegfried W. de Laat, & W. Kruijer. (1992). EGF-inducedjun B-expression in transfected P19 embryonal carcinoma cells expressing EGF-receptors is dependent on Jun D. Nucleic Acids Research. 20(1). 125–130. 9 indexed citations

Peppelenbosch, Maikel P., Leon G.J. Tertoolen, Jeroen den Hertog, & Siegfried W. de Laat. (1992). Epidermal growth factor activates calcium channels by phospholipase A25-lipoxygenase-mediated leukotriene C4 production. Cell. 69(2). 295–303. 163 indexed citations

Slager, H.G., et al.. (1991). Differential localization of TGF-β2 in mouse preimplantation and early postimplantation development. Developmental Biology. 145(2). 205–218. 70 indexed citations

10.

Tertoolen, Leon G.J., et al.. (1990). Intercellular communication is cell cycle modulated during early Xenopus laevis development.. The Journal of Cell Biology. 110(1). 115–121. 10 indexed citations

11.

Belzen, Nico van, Philip J. Rijken, W. J. Hage, et al.. (1988). Direct visualization and quantitative analysis of epidermal growth factor‐induced receptor clustering. Journal of Cellular Physiology. 134(3). 413–420. 45 indexed citations

12.

Boonstra, Johannes, Leon G.J. Tertoolen, Christine L. Mummery, & Siegfried W. de Laat. (1988). Regulation of intracellular pH during the G1/S-phase transition of the neuroblastoma cell cycle. Experimental Cell Research. 174(2). 521–524. 4 indexed citations

13.

Tilly, Ben C., Peter A. van Paridon, Ingrid Verlaan, Siegfried W. de Laat, & Wouter H. Moolenaar. (1988). Epidermal-growth-factor-induced formation of inositol phosphates in human A431 cells. Differences from the effect of bradykinin. Biochemical Journal. 252(3). 857–863. 53 indexed citations

14.

Zoelen, E.J.J. van, et al.. (1987). Production of transforming growth factors by simian sarcoma virus-transformed cells.. PubMed. 47(6). 1582–7. 13 indexed citations

15.

Defize, Libert H.K. & Siegfried W. de Laat. (1986). Chapter 15 Structural and functional aspects of epidermal growth factor (EGF) and its receptor. Progress in brain research. 69. 169–182. 4 indexed citations

16.

Defize, Libert H.K., Wouter H. Moolenaar, Paul T. van der Saag, & Siegfried W. de Laat. (1986). Dissociation of cellular responses to epidermal growth factor using anti-receptor monoclonal antibodies.. The EMBO Journal. 5(6). 1187–1192. 56 indexed citations

17.

Snoek, Gerry T., Ian M. Rosenberg, Siegfried W. de Laat, & Carlos Gitler. (1986). The interaction of protein kinase C and other specific cytoplasmic proteins with phospholipid bilayers. Biochimica et Biophysica Acta (BBA) - Biomembranes. 860(2). 336–344. 18 indexed citations

18.

Gispen, W.H., C.J. van Dongen, Moshe Hershkowitz, H. Zwiers, & Siegfried W. de Laat. (1983). Lipid fluidity and phosphoinositiDe metabolism in brain membranes of aged rats: Effects of ACTH1-24. Utrecht University Repository (Utrecht University). 101–114. 6 indexed citations

19.

Zoelen, E.J.J. van, Christine L. Mummery, J. Boonstra, Paul T. van der Saag, & Siegfried W. de Laat. (1983). Membrane regulation of the Na⁺, K⁺‐ATPase during the neuroblastoma cell cycle: Correlation with protein lateral mobility. Journal of Cellular Biochemistry. 21(1). 77–91. 12 indexed citations

20.

Bluemink, John G. & Siegfried W. de Laat. (1973). NEW MEMBRANE FORMATION DURING CYTOKINESIS IN NORMAL AND CYTOCHALASIN B-TREATED EGGS OF XENOPUS LAEVIS . The Journal of Cell Biology. 59(1). 89–108. 154 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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