Philippe Beaune

23.1k total citations · 2 hit papers
352 papers, 18.7k citations indexed

About

Philippe Beaune is a scholar working on Pharmacology, Molecular Biology and Oncology. According to data from OpenAlex, Philippe Beaune has authored 352 papers receiving a total of 18.7k indexed citations (citations by other indexed papers that have themselves been cited), including 191 papers in Pharmacology, 112 papers in Molecular Biology and 89 papers in Oncology. Recurrent topics in Philippe Beaune's work include Pharmacogenetics and Drug Metabolism (184 papers), Drug Transport and Resistance Mechanisms (61 papers) and Drug-Induced Hepatotoxicity and Protection (40 papers). Philippe Beaune is often cited by papers focused on Pharmacogenetics and Drug Metabolism (184 papers), Drug Transport and Resistance Mechanisms (61 papers) and Drug-Induced Hepatotoxicity and Protection (40 papers). Philippe Beaune collaborates with scholars based in France, United States and Germany. Philippe Beaune's co-authors include F. Peter Guengerich, Marie‐Anne Loriot, Isabelle de Waziers, P. Kremers, Pierre Laurent‐Puig, Jean‐Charles Gautier, Christophe Legendre, Dany Anglicheau, Daniel Mansuy and Jean-Pierre Flinois and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Philippe Beaune

345 papers receiving 18.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism.

1986 668 citations Philippe Beaune, P. Kremers et al. profile →
Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1

1990 493 citations Philippe Beaune et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Philippe Beaune France	75	9.2k	5.7k	5.1k	2.3k	1.8k	352	18.7k
Ulrich M. Zanger Germany	74	10.1k 1.1×	6.8k 1.2×	5.1k 1.0×	3.1k 1.4×	1.1k 0.6×	197	19.8k
Steven Wrighton United States	71	11.1k 1.2×	6.7k 1.2×	3.9k 0.8×	2.6k 1.2×	704 0.4×	172	17.1k
Erin G. Schuetz United States	77	9.8k 1.1×	9.7k 1.7×	4.7k 0.9×	4.0k 1.8×	1.0k 0.6×	198	19.9k
Ann K. Daly United Kingdom	74	9.9k 1.1×	4.5k 0.8×	4.3k 0.8×	2.3k 1.0×	1.0k 0.6×	282	20.5k
Paul B. Watkins United States	73	11.5k 1.2×	6.2k 1.1×	3.5k 0.7×	3.2k 1.4×	747 0.4×	246	19.9k
Jürgen Brockmöller Germany	65	5.1k 0.6×	4.0k 0.7×	4.0k 0.8×	2.7k 1.2×	1.0k 0.6×	236	13.8k
Kenneth E. Thummel United States	73	11.5k 1.3×	7.2k 1.3×	3.1k 0.6×	4.7k 2.1×	479 0.3×	263	20.2k
Michel Eichelbaum Germany	87	12.0k 1.3×	11.4k 2.0×	4.7k 0.9×	6.8k 3.0×	830 0.5×	335	25.4k
Tsutomu Shimada Japan	75	11.0k 1.2×	5.0k 0.9×	6.7k 1.3×	1.1k 0.5×	3.6k 2.0×	317	20.2k
Stephen C. Strom United States	73	4.5k 0.5×	4.4k 0.8×	6.4k 1.3×	1.6k 0.7×	1.3k 0.8×	247	19.7k

Countries citing papers authored by Philippe Beaune

Since Specialization

Citations

This map shows the geographic impact of Philippe Beaune's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Philippe Beaune with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Philippe Beaune more than expected).

Fields of papers citing papers by Philippe Beaune

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philippe Beaune. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philippe Beaune. The network helps show where Philippe Beaune may publish in the future.

Co-authorship network of co-authors of Philippe Beaune

This figure shows the co-authorship network connecting the top 25 collaborators of Philippe Beaune. A scholar is included among the top collaborators of Philippe Beaune based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Philippe Beaune. Philippe Beaune is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Villoutreix, Bruno O., Rajagopal Krishnamoorthy, Ryad Tamouza, Marion Leboyer, & Philippe Beaune. (2021). Chemoinformatic Analysis of Psychotropic and Antihistaminic Drugs in the Light of Experimental Anti-SARS-CoV-2 Activities. SHILAP Revista de lepidopterología. Volume 14. 71–85. 11 indexed citations

Bimonte, Sandro, et al.. (2016). Une architecture orientée services pour l'OLAP Spatial.. HAL (Le Centre pour la Communication Scientifique Directe). 17–24. 1 indexed citations

Pallet, Nicolas, Anne‐Sophie Jannot, Isabelle Étienne, et al.. (2015). Kidney Transplant Recipients Carrying the CYP3A4*22 Allelic Variant Have Reduced Tacrolimus Clearance and Often Reach Supratherapeutic Tacrolimus Concentrations. American Journal of Transplantation. 15(3). 800–805. 54 indexed citations

Narjoz, Céline, Michael Montemurro, William D. Figg, et al.. (2014). Important Role of CYP2J2 in Protein Kinase Inhibitor Degradation: A Possible Role in Intratumor Drug Disposition and Resistance. PLoS ONE. 9(5). e95532–e95532. 28 indexed citations

Pinet, François, et al.. (2014). Performance optimization of grid aggregation in spatial data warehouses. International Journal of Digital Earth. 8(12). 970–988. 1 indexed citations

Neuraz, Antoine, Laurent Chouchana, Georgia Malamut, et al.. (2013). Phenome-Wide Association Studies on a Quantitative Trait: Application to TPMT Enzyme Activity and Thiopurine Therapy in Pharmacogenomics. PLoS Computational Biology. 9(12). e1003405–e1003405. 40 indexed citations

Boige, Valérie, Jean Mendiboure, Jean‐Pierre Pignon, et al.. (2010). Pharmacogenetic assessment of toxicity and outcome in patients with metastatic colorectal cancer treated with LV5FU2, FOLFOX, and FOLFIRI: FFCD 2000-05. American Journal of Clinical Oncology. 28(15). 2556–2564. 3 indexed citations

Mulot, Claire, Isabelle Stücker, Jacqueline Clavel, Philippe Beaune, & Marie‐Anne Loriot. (2005). Collection of Human Genomic DNA From Buccal Cells for Genetics Studies: Comparison Between Cytobrush, Mouthwash, and Treated Card. BioMed Research International. 2005(3). 291–296. 58 indexed citations

Beaune, Philippe, et al.. (2003). Conception multi-agent d'un système d'aide à la décision collective Justification automatique pour la confrontation des opinions. HAL (Le Centre pour la Communication Scientifique Directe). 22. 359–363. 1 indexed citations

10.

Cauchi, Stéphane, Isabelle Stücker, Sylvie Cénée, et al.. (2003). Structure and polymorphisms of human aryl hydrocarbon receptor repressor (AhRR) gene in a French population: relationship with CYP1A1 inducibility and lung cancer.. PubMed. 13(6). 339–47. 33 indexed citations

11.

Vercouter, Laurent, et al.. (2000). Towards Open Distributed Information Systems By the Way of a Multi-Agent Conception Framework. HAL (Le Centre pour la Communication Scientifique Directe). 1 indexed citations

12.

Dansette, Patrick M., et al.. (1998). Drug-induced immunotoxicity. European Journal of Drug Metabolism and Pharmacokinetics. 23(4). 443–451. 56 indexed citations

13.

Belloc, Claire, José Cosme, Sylvaine Lecoeur, et al.. (1996). Human cytochromes P450 expressed in Escherichia coli: production of specific antibodies. Toxicology. 106(1-3). 207–219. 41 indexed citations

14.

Roland, Nathalie, et al.. (1996). Hepatic Cytochrome P450 and UDP-Glucuronosyl Transferase Are Affected by Five Sources of Dietary Fiber in Germ-Free Rats. Journal of Nutrition. 126(2). 403–409. 10 indexed citations

15.

Carrière, Véronique, Philippe Costet, P H Cugnenc, et al.. (1996). CYP3A5 is the major cytochrome P450 3A expressed in human colon and colonic cell lines. Environmental Toxicology and Pharmacology. 2(4). 381–388. 36 indexed citations

16.

Robin, Marie‐Anne, Jacqueline Loeper, Anne‐Marie Durand‐Schneider, et al.. (1995). Cytochrome P4502B follows a vesicular route to the plasma membrane in cultured rat hepatocytes. Gastroenterology. 108(4). 1110–1123. 49 indexed citations

17.

Pairon, J.‐C., Nesrine Trabelsi, Annie Buard, et al.. (1994). Cell Localization and Regulation of Expression of Cytochrome P450 1A1 and 2B1 in Rat Lung After Induction With 3-Methylcholanthrene using mRNA Hybridization and Immunohistochemistry. American Journal of Respiratory Cell and Molecular Biology. 11(4). 386–396. 10 indexed citations

18.

Bourdi, Mohammed, Jean‐Charles Gautier, Dominique Larrey, et al.. (1992). Anti-liver microsomes autoantibodies and dihydralazine-induced hepatitis: specificity of autoantibodies and inductive capacity of the drug.. Molecular Pharmacology. 42(2). 280–285. 56 indexed citations

19.

Dréano, Yvonne, et al.. (1991). Identification of the cytochrome P450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes. Biochemical Pharmacology. 41(12). 1911–1919. 162 indexed citations

20.

Waziers, Isabelle de, Paul‐Henri Cugnenc, Alexander Berger, J.P. Leroux, & Philippe Beaune. (1991). Drug-metabolizing enzyme expression in human normal, peritumoral and tumoral colorectal tissue samples. Carcinogenesis. 12(5). 905–909. 38 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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