Ivar Roots

20.8k total citations · 3 hit papers
253 papers, 16.4k citations indexed

About

Ivar Roots is a scholar working on Pharmacology, Molecular Biology and Oncology. According to data from OpenAlex, Ivar Roots has authored 253 papers receiving a total of 16.4k indexed citations (citations by other indexed papers that have themselves been cited), including 88 papers in Pharmacology, 70 papers in Molecular Biology and 58 papers in Oncology. Recurrent topics in Ivar Roots's work include Pharmacogenetics and Drug Metabolism (85 papers), Drug Transport and Resistance Mechanisms (49 papers) and Pharmacological Effects and Toxicity Studies (37 papers). Ivar Roots is often cited by papers focused on Pharmacogenetics and Drug Metabolism (85 papers), Drug Transport and Resistance Mechanisms (49 papers) and Pharmacological Effects and Toxicity Studies (37 papers). Ivar Roots collaborates with scholars based in Germany, United States and Czechia. Ivar Roots's co-authors include Jürgen Brockmöller, Ingolf Cascorbi, Steffen Bauer, Christoph Sachse, Julia Kirchheiner, Andreas Johne, Reinhold Kerb, Thomas Gerloff, Alfred G. Hildebrandt and Ulrich Brinkmann and has published in prestigious journals such as Proceedings of the National Academy of Sciences, The Lancet and Journal of Clinical Oncology.

In The Last Decade

Ivar Roots

252 papers receiving 15.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

2000 2.0k citations J. Brockmöller, Andreas Johne et al. profile →
Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.

1997 803 citations Jürgen Brockmöller, Steffen Bauer et al. profile →
Functional significance of a C→A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine

1999 579 citations Jürgen Brockmöller, Steffen Bauer et al. British Journal of Clinical Pharmacology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ivar Roots Germany	68	5.9k	4.9k	4.7k	3.3k	1.8k	253	16.4k
Jürgen Brockmöller Germany	65	5.1k 0.9×	4.0k 0.8×	4.0k 0.9×	2.7k 0.8×	1.6k 0.9×	236	13.8k
Ulrich M. Zanger Germany	74	10.1k 1.7×	6.8k 1.4×	5.1k 1.1×	3.1k 0.9×	1.7k 1.0×	197	19.8k
Paul B. Watkins United States	73	11.5k 2.0×	6.2k 1.3×	3.5k 0.8×	3.2k 0.9×	2.2k 1.3×	246	19.9k
Steven Wrighton United States	71	11.1k 1.9×	6.7k 1.4×	3.9k 0.8×	2.6k 0.8×	1.8k 1.0×	172	17.1k
Ingolf Cascorbi Germany	57	2.7k 0.5×	5.6k 1.1×	4.1k 0.9×	3.4k 1.0×	758 0.4×	234	13.1k
Kenneth E. Thummel United States	73	11.5k 2.0×	7.2k 1.5×	3.1k 0.7×	4.7k 1.4×	1.8k 1.0×	263	20.2k
Richard B. Kim Canada	74	5.7k 1.0×	9.1k 1.8×	3.7k 0.8×	4.7k 1.4×	1.5k 0.9×	243	18.5k
Erin G. Schuetz United States	77	9.8k 1.7×	9.7k 2.0×	4.7k 1.0×	4.0k 1.2×	1.1k 0.6×	198	19.9k
Tsuyoshi Yokoi Japan	67	7.2k 1.2×	4.8k 1.0×	6.2k 1.3×	1.7k 0.5×	1.6k 0.9×	369	16.2k
Mikko Niemi Finland	64	5.5k 0.9×	6.2k 1.2×	2.5k 0.5×	3.2k 1.0×	1.5k 0.9×	277	15.2k

Countries citing papers authored by Ivar Roots

Since Specialization

Citations

This map shows the geographic impact of Ivar Roots's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ivar Roots with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ivar Roots more than expected).

Fields of papers citing papers by Ivar Roots

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ivar Roots. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ivar Roots. The network helps show where Ivar Roots may publish in the future.

Co-authorship network of co-authors of Ivar Roots

This figure shows the co-authorship network connecting the top 25 collaborators of Ivar Roots. A scholar is included among the top collaborators of Ivar Roots based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ivar Roots. Ivar Roots is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Tzvetkov, Mladen V., Jürgen Brockmöller, Ivar Roots, & Julia Kirchheiner. (2008). Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment. Pharmacogenetics and Genomics. 18(6). 495–506. 63 indexed citations

Bauer, Steffen, et al.. (2008). St John’s wort extract (Ze 117) does not alter the pharmacokinetics of a low-dose oral contraceptive. European Journal of Clinical Pharmacology. 65(3). 287–294. 29 indexed citations

Goldammer, Mark, et al.. (2008). An Anomalous Haplotype Distribution of the Arrestin Domain–Containing 4 Gene ( ARRDC4 ) Haplotypes in Caucasians. Genetic Testing. 12(1). 147–152. 2 indexed citations

Diefenbach, Konstanze, Christian Meisel, Ingo Fietze, et al.. (2006). Systematic Analysis of Sequence Variability of the Endothelin-1 Gene: A Prerequisite for Association Studies. Genetic Testing. 10(3). 163–168. 5 indexed citations

Kirchheiner, Julia, et al.. (2006). A 40-basepair VNTR polymorphism in the dopamine transporter (DAT1) gene and the rapid response to antidepressant treatment. The Pharmacogenomics Journal. 7(1). 48–55. 76 indexed citations

Bauer, Steffen, et al.. (2005). Quantification of pravastatin in human plasma and urine after solid phase extraction using high performance liquid chromatography with ultraviolet detection. Journal of Chromatography B. 818(2). 257–262. 38 indexed citations

Kirchheiner, Julia, et al.. (2004). The CYP2C9 polymorphism: from enzyme kinetics to clinical dose recommendations. Personalized Medicine. 1(1). 63–84. 35 indexed citations

Krusekopf, Solveigh, et al.. (2003). Time-dependent transcriptional induction of CYP1A1, CYP1A2 and CYP1B1 mRNAs by H⁺/K⁺-ATPase inhibitors and other xenobiotics. Xenobiotica. 33(2). 107–118. 39 indexed citations

Oselin, Kersti, P.M. Mrozikiewicz, Rein Pähkla, & Ivar Roots. (2003). Quantitative determination of the human MRP1 and MRP2 mRNA expression in FACS‐sorted peripheral blood CD4⁺, CD8⁺, CD19⁺, and CD56⁺cells. European Journal Of Haematology. 71(2). 119–123. 32 indexed citations

10.

Gerloff, Thomas, Andreas Geier, Ivar Roots, Peter J. Meier, & Carsten Gartung. (2002). Functional analysis of the rat bile salt export pump gene promoter. European Journal of Biochemistry. 269(14). 3495–3503. 37 indexed citations

11.

Meisel, Christian, Vahid Afshar‐Kharghan, Ingolf Cascorbi, et al.. (2001). Role of Kozak sequence polymorphism of platelet glycoprotein Ibα as a risk factor for coronary artery disease and catheter interventions. Journal of the American College of Cardiology. 38(4). 1023–1027. 21 indexed citations

12.

Stangl, Karl, Ingolf Cascorbi, Michael Laule, et al.. (2000). Elevated serum leptin in patients with coronary artery disease: no association with the Trp64Arg polymorphism of the β3-adrenergic receptor. International Journal of Obesity. 24(3). 369–375. 21 indexed citations

13.

Mrozikiewicz, P.M., Ingolf Cascorbi, Sabine Ziemer, et al.. (2000). Reduced procedural risk for coronary catheter interventions in carriers of the coagulation factor VII-Gln353 gene. Journal of the American College of Cardiology. 36(5). 1520–1525. 15 indexed citations

14.

Mai, Ingrid, H. Krüger, Klemens Budde, et al.. (2000). Hazardous pharmacokinetic interaction of Saint John’s wort (Hypericum perforatum) with the immunosuppressant cyclosporin. International Journal of Clinical Pharmacology and Therapeutics. 38(10). 500–502. 83 indexed citations

15.

Cascorbi, Ingolf, Michael Laule, P.M. Mrozikiewicz, et al.. (1999). Mutations in the human paraoxonase 1 gene. Pharmacogenetics. 9(6). 755–762. 47 indexed citations

16.

Schöps, Wolfgang, Klaus Golka, Meinolf Blaszkewicz, et al.. (1997). Untersuchung zur klinischen Relevanz der Acetyliererphänotypisierung bei 196 Urotheltumorpatienten. Der Urologe. 36(1). 64–67. 4 indexed citations

17.

Püchler, Kurt, Katja‐Martina Eckl, Lutz Fritsche, et al.. (1997). Pharmacokinetics of temocapril and temocaprilat after 14 once daily oral doses of temocapril in hypertensive patients with varying degrees of renal impairment. British Journal of Clinical Pharmacology. 44(6). 531–536. 5 indexed citations

18.

Donath, Frank, et al.. (1996). Oral bioavailability of bromelain and trypsin after repeated oral administration of a commercial polyenzyme preparation. European Journal of Clinical Pharmacology. 50(6). 548. 2 indexed citations

19.

Rost, Karl Ludwig & Ivar Roots. (1994). Accelerated caffeine metabolism after omeprazole treatment is indicated by urinary metabolite ratios: Coincidence with plasma clearance and breath test. Clinical Pharmacology & Therapeutics. 55(4). 402–411. 86 indexed citations

20.

Brockmöller, Jürgen, et al.. (1991). Determination of S-carboxymethyl-l-cysteine and some of its metabolites in urine and serum by high-performance liquid chromatography using fluorescent pre-column labelling. Journal of Chromatography B Biomedical Sciences and Applications. 571(1-2). 133–147. 22 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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