Ivar Roots

20.8k citations

253 papers · 16.4k indexed · 3 hit papers · h-index 68

Pharmacology top 0.01%
- Pharmacogenetics and Drug Metabolism 85
- Antibiotics Pharmacokinetics and Efficacy 13
Transplantation top 0.5%
Oncology top 0.2%
- Drug Transport and Resistance Mechanisms 49
Pediatrics, Perinatology and Child Health top 0.1%
- Pharmacological Effects and Toxicity Studies 37
Biochemistry top 0.2%
- Eicosanoids and Hypertension Pharmacology 13
Molecular Biology
- Glutathione Transferases and Polymorphisms 26
Plant Science
- Natural Compound Pharmacology Studies 15
Pharmaceutical Science
- Chemical Reactions and Isotopes 12

Co-authors: Jürgen Brockmöller Ingolf Cascorbi Steffen Bauer Christoph Sachse Julia Kirchheiner Andreas Johne Reinhold Kerb Thomas Gerloff
Cited by: Pharmacology Transplantation Oncology
Journals: European Journal of Clinical Pharmacology (22 papers)Clinical Pharmacology & Therapeutics (16 papers)British Journal of Clinical Pharmacology (12 papers)
Partner nations: Germany United States Czechia

In The Last Decade

Ivar Roots

252 papers receiving 15.8k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2000 Proceedings of the National Academy of Sciences
1999 British Journal of Clinical Pharmacology
1997 PubMed

Peers

Countries citing papers authored by Ivar Roots

Since Specialization

Citations

This map shows the geographic impact of Ivar Roots's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ivar Roots with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ivar Roots more than expected).

Fields of papers citing papers by Ivar Roots

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ivar Roots. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ivar Roots. The network helps show where Ivar Roots may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Ivar Roots, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ivar Roots Line = papers co-authored together Ivar Roots links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	An Anomalous Haplotype Distribution of the Arrestin Domain–Containing 4 Gene ( ARRDC4 ) Haplotypes in Caucasians Genetic Testing ·Gun Hwa Lee,Mark Goldammer,Laís Salgueiro Garcez,Lee A. Ritscher,Andreas Johne,P.M. Mrozikiewicz,Ivar Roots,Karla Köpke	2008	2
2	Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment Pharmacogenetics and Genomics ·Mladen V. Tzvetkov,Jürgen Brockmöller,Ivar Roots,Julia Kirchheiner	2008	63
3	St John’s wort extract (Ze 117) does not alter the pharmacokinetics of a low-dose oral contraceptive European Journal of Clinical Pharmacology ·Jennie de Verdier,Steffen Bauer,Vanesa TEJMLOVÁ,Ivar Roots,A. Brattström	2008	29
4	Systematic Analysis of Sequence Variability of the Endothelin-1 Gene: A Prerequisite for Association Studies Genetic Testing ·Konstanze Diefenbach,Helen Frik,Christian Meisel,Ingo Fietze,Karl Stangl,Ivar Roots,Karla Köpke	2006	5
5	A 40-basepair VNTR polymorphism in the dopamine transporter (DAT1) gene and the rapid response to antidepressant treatment The Pharmacogenomics Journal ·Julia Kirchheiner,Emad Hasan,Marianus Yohanes Gaharpung,Michael Bauer,Ivar Roots,Jürgen Brockmöller	2006	76
6	Quantification of pravastatin in human plasma and urine after solid phase extraction using high performance liquid chromatography with ultraviolet detection Journal of Chromatography B ·Steffen Bauer,Jessica Mwinyi,А. А. Гольдберг,Thomas Gerloff,Ivar Roots	2005	38
7	No Relevant Interaction with Alprazolam, Caffeine, Tolbutamide, and Digoxin by Treatment with a Low-Hyperforin St John’s Wort Extract Planta Medica ·Gerhard Arold,Frank Donath,Ana Cláudia do Nascimento Coutinho,Konstanze Diefenbach,Steffen Bauer,Hans‐Heinrich Henneicke‐von Zepelin,M. Friede,Ivar Roots	2005	70
8	Quantitative determination of the human MRP1 and MRP2 mRNA expression in FACS‐sorted peripheral blood CD4⁺, CD8⁺, CD19⁺, and CD56⁺cells European Journal Of Haematology ·Kersti Oselin,P.M. Mrozikiewicz,Rein Pähkla,Ivar Roots	2003	32
9	Time-dependent transcriptional induction of CYP1A1, CYP1A2 and CYP1B1 mRNAs by H⁺/K⁺-ATPase inhibitors and other xenobiotics Xenobiotica ·Solveigh Krusekopf,Ivar Roots,Alfred G. Hildebrandt,長嶺竹明	2003	39
10	Functional analysis of the rat bile salt export pump gene promoter European Journal of Biochemistry ·Thomas Gerloff,Andreas Geier,Ivar Roots,Peter J. Meier,Carsten Gartung	2002	37
11	Role of Kozak sequence polymorphism of platelet glycoprotein Ibα as a risk factor for coronary artery disease and catheter interventions Journal of the American College of Cardiology ·Christian Meisel,Vahid Afshar‐Kharghan,Ingolf Cascorbi,Michael Laule,Verena Stangl,Frank Hatchett,Gert Baumann,José A. López,Ivar Roots,Karl Stangl	2001	21
12	Identification of six methylenetetrahydrofolate reductase (MTHFR) genotypes resulting from common polymorphisms: impact on plasma homocysteine levels and development of coronary artery disease Atherosclerosis ·Christian Meisel,Ingolf Cascorbi,Thomas Gerloff,Verena Stangl,Michael Laule,J. M. Müller,Klaus D. Wernecke,Gert Baumann,Ivar Roots,Karl Stangl	2001	42
13	Reduced procedural risk for coronary catheter interventions in carriers of the coagulation factor VII-Gln353 gene Journal of the American College of Cardiology ·P.M. Mrozikiewicz,Ingolf Cascorbi,Sabine Ziemer,Michael Laule,Christian Meisel,Verena Stangl,Wolfgang Rutsch,Klaus D. Wernecke,Gert Baumann,Ivar Roots,Karl Stangl	2000	15
14	Elevated serum leptin in patients with coronary artery disease: no association with the Trp64Arg polymorphism of the β3-adrenergic receptor International Journal of Obesity ·Karl Stangl,Ingolf Cascorbi,Michael Laule,Verena Stangl,Merly C. Vogt,Sabine Ziemer,Ivar Roots,K. D. Wernecke,Gert Baumann,Hans Hauner	2000	21
15	CYP2D6 Genotyping as an alternative to phenotyping for determination of metabolic status in a clinical trial setting PubMed ·C.D. Karapetyan,Hélio Guedes de Carvalho,N H Loc,David L. Friedman,B. Michael Silber,Patrice M. Milos,Christoph Sachse,Jürgen Brockmöller,Ivar Roots	2000	67
16	Quantification of the antipsychotics flupentixol and haloperidol in human serum by high-performance liquid chromatography with ultraviolet detection Journal of Chromatography B Biomedical Sciences and Applications ·H. L. Wray,Steffen Bauer,Ivar Roots,Jürgen Brockmöller	1998	35
17	Oral bioavailability of bromelain and trypsin after repeated oral administration of a commercial polyenzyme preparation European Journal of Clinical Pharmacology ·Brandon L. Phillips,Frank Donath,Ana Cláudia do Nascimento Coutinho,Steffen Bauer,Ivar Roots	1996	2
18	Polymerase Chain Reaction (PCR)-Based Construction of a Competitor Target for Quantitative Reverse Transcriptase PCR Measurement of Cytochrome P450 1A1 mRNA Analytical Biochemistry ·Roland Frötschl,長嶺竹明,Alfred G. Hildebrandt,Ivar Roots,Jürgen Brockmöller	1996	2
19	Correlation between trans-stilbene oxide-glutathione conjugation activity and the deletion mutation in the glutathione S-transferase class Mu gene detected by polymerase chain reaction Biochemical Pharmacology ·Jürgen Brockmöller,D. H. E. Gross,Reinhold Kerb,Nikolaos Drakoulis,Ivar Roots	1992	88
20	NEUROTOXICITY CAUSED BY A HIGH CYCLOSPORINE METABOLITE LEVEL Transplantation ·Ulrich Kunzendorf,Jürgen Brockmöller,Friederike Jochimsen,Ivar Roots,G. Offermann	1989	18

About Ivar Roots

Ivar Roots is a scholar working on Pharmacology, Transplantation and Biochemistry, having authored 253 papers that have together received 16.4k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (85 papers), Drug Transport and Resistance Mechanisms (49 papers), Pharmacological Effects and Toxicity Studies (37 papers), Glutathione Transferases and Polymorphisms (26 papers), Natural Compound Pharmacology Studies (15 papers), Eicosanoids and Hypertension Pharmacology (13 papers), Antibiotics Pharmacokinetics and Efficacy (13 papers) and Chemical Reactions and Isotopes (12 papers). The work is most often cited by research in Pharmacology (5.9k citations), Transplantation (543 citations) and Oncology (4.9k citations). Ivar Roots has collaborated with scholars based in Germany, United States and Czechia. Frequent co-authors include Jürgen Brockmöller, Ingolf Cascorbi, Steffen Bauer, Christoph Sachse, Julia Kirchheiner, Andreas Johne, Reinhold Kerb, Thomas Gerloff, Alfred G. Hildebrandt and Ulrich Brinkmann. Their work appears in journals such as European Journal of Clinical Pharmacology, Clinical Pharmacology & Therapeutics, British Journal of Clinical Pharmacology, Biochemical Pharmacology and Pharmacogenetics and Genomics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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