Danny D. Shen

15.8k total citations · 3 hit papers
223 papers, 12.1k citations indexed

About

Danny D. Shen is a scholar working on Pediatrics, Perinatology and Child Health, Pharmacology and Oncology. According to data from OpenAlex, Danny D. Shen has authored 223 papers receiving a total of 12.1k indexed citations (citations by other indexed papers that have themselves been cited), including 67 papers in Pediatrics, Perinatology and Child Health, 56 papers in Pharmacology and 52 papers in Oncology. Recurrent topics in Danny D. Shen's work include Pharmacological Effects and Toxicity Studies (51 papers), Pharmacogenetics and Drug Metabolism (47 papers) and Drug Transport and Resistance Mechanisms (44 papers). Danny D. Shen is often cited by papers focused on Pharmacological Effects and Toxicity Studies (51 papers), Pharmacogenetics and Drug Metabolism (47 papers) and Drug Transport and Resistance Mechanisms (44 papers). Danny D. Shen collaborates with scholars based in United States, China and South Africa. Danny D. Shen's co-authors include Kenneth E. Thummel, Kent L. Kunze, James D. Perkins, Mary F. Paine, Christopher L. Marsh, Daniel L. Azarnoff, Kimberly D.K. Adkison, Brian Phillips, Mary F. Hébert and Bojan Lalovic and has published in prestigious journals such as Circulation, Journal of Clinical Investigation and SHILAP Revista de lepidopterología.

In The Last Decade

Danny D. Shen

222 papers receiving 11.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Characterization of Interintestinal and Intraintestinal Variations in Human CYP3A-Dependent Metabolism

1997 645 citations Mary F. Paine, Danny D. Shen et al. profile →
Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism*

1996 509 citations Kenneth E. Thummel, Mary F. Paine et al. profile →
Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update

2014 453 citations Danny D. Shen et al. profile →

Peers

Countries citing papers authored by Danny D. Shen

Since Specialization

Citations

This map shows the geographic impact of Danny D. Shen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Danny D. Shen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Danny D. Shen more than expected).

Fields of papers citing papers by Danny D. Shen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Danny D. Shen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Danny D. Shen. The network helps show where Danny D. Shen may publish in the future.

Co-authorship network of co-authors of Danny D. Shen

This figure shows the co-authorship network connecting the top 25 collaborators of Danny D. Shen. A scholar is included among the top collaborators of Danny D. Shen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Danny D. Shen. Danny D. Shen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Physiologically based Pharmacokinetic Model Validated to Enable Predictions Of Multiple Drugs in a Long-acting Drug-combination Nano-Particles (DcNP): Confirmation with 3 HIV Drugs, Lopinavir, Ritonavir, and Tenofovir in DcNP Products 2024 ·Journal of Pharmaceutical Sciences ·(unknown), Danny D. Shen, (unknown), Rodney J. Y. Ho	8
2	Co‐consuming green tea with raloxifene decreases raloxifene systemic exposure in healthy adult participants 2023 ·Clinical and Translational Science ·John Clarke, (unknown), Dandan Tian, Trevor O. Kirby, (unknown), (unknown), (unknown), Matthew E. Layton, John R. White, Nadja B. Cech, Kenneth E. Thummel, Jeannine S. McCune, Danny D. Shen, Mary F. Paine	8
3	Physiologically Based Pharmacokinetic Modeling of 3 HIV Drugs in Combination and the Role of Lymphatic System after Subcutaneous Dosing. Part 1: Model for the Free-Drug Mixture 2021 ·Journal of Pharmaceutical Sciences ·(unknown), Laura M. Shireman, Danny D. Shen, Rodney J. Y. Ho	9
4	Physiologically Based Pharmacokinetic Modeling of 3 HIV Drugs in Combination and the Role of Lymphatic System after Subcutaneous Dosing. Part 2: Model for the Drug-combination Nanoparticles 2021 ·Journal of Pharmaceutical Sciences ·(unknown), Danny D. Shen, Rodney J. Y. Ho	15
5	Relationship of Phosphatidylethanol Biomarker to Self‐Reported Alcohol Drinking Patterns in Older and Middle‐Age Adults 2020 ·Alcoholism Clinical and Experimental Research ·Monique M. Cherrier, Laura M. Shireman, (unknown), (unknown), (unknown), Andrew J. Saxon, Tracy L. Simpson, (unknown), Danny D. Shen	13
6	Integration of Computational and Experimental Approaches to Elucidate Mechanisms of First-Pass Lymphatic Drug Sequestration and Long-Acting Pharmacokinetics of the Injectable Triple-HIV Drug Combination TLC-ART 101 2020 ·Journal of Pharmaceutical Sciences ·(unknown), Laura M. Shireman, Lisa A. McConnachie, Josefin Koehn, (unknown), (unknown), Sarah Lane, Ann C. Collier, Danny D. Shen, Rodney J. Y. Ho	16
7	Disposition of Methamphetamine and Major Metabolites in Mice: Role of Organic Cation Transporter 3 in Tissue-Selective Accumulation of Para-Hydroxymethamphetamine 2018 ·Drug Metabolism and Disposition ·David J. Wagner, Laura M. Shireman, (unknown), Danny D. Shen, Joanne Wang	16
8	Gut Microbiota Modulates Interactions Between Polychlorinated Biphenyls and Bile Acid Homeostasis 2018 ·Toxicological Sciences ·Sunny Lihua Cheng, Xueshu Li, Hans‐Joachim Lehmler, Brian Phillips, Danny D. Shen, Julia Yue Cui	52
9	Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity 2017 ·JCI Insight ·Shih‐Yu Chang, Elijah J. Weber, Viktoriya S. Sidorenko, Alenka Chapron, Catherine K. Yeung, Chunying Gao, Qingcheng Mao, Danny D. Shen, Joanne Wang, Thomas A. Rosenquist, Kathleen G. Dickman, Thomas Neumann, Arthur P. Grollman, Edward J. Kelly, Jonathan Himmelfarb, David L. Eaton	138
10	Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress 2015 ·BMC Nephrology ·Catherine K. Yeung, Frederic T. Billings, (unknown), Baback Roshanravan, Lori Linke, (unknown), Suhail Ahmad, Baohai Shao, Danny D. Shen, T. Alp İkizler, Jonathan Himmelfarb	48
11	Specialty Supplement Use and Biologic Measures of Oxidative Stress and DNA Damage 2013 ·Cancer Epidemiology Biomarkers & Prevention ·Elizabeth D. Kantor, Cornelia M. Ulrich, Robert W. Owen, Peter Schmezer, Marian L. Neuhouser, Johanna W. Lampe, Ulrike Peters, Danny D. Shen, Thomas L. Vaughan, Emily White	12
12	Pharmacokinetics of Tacrolimus During Pregnancy 2012 ·Therapeutic Drug Monitoring ·Songmao Zheng, Thomas R. Easterling, Jason G. Umans, Menachem Miodovnik, Justina C. Calamia, Kenneth E. Thummel, Danny D. Shen, Connie L. Davis, Mary F. Hébert	80
13	MDR1 G1199A polymorphism alters permeability of HIV protease inhibitors across P-glycoprotein-expressing epithelial cells 2005 ·AIDS ·Erica L. Woodahl, Ziping Yang, Tot Bui, Danny D. Shen, Rodney J. Y. Ho	48
14	An RT-PCR-based Strategy to Estimate Full-Length CYP2D6 mRNA Copy Number 2004 ·Genetic Testing ·Lisa A. McConnachie, Miklós Bodor, Brian Phillips, Edward J. Kelly, Danny D. Shen, Rodney J. Y. Ho	3
15	Valproic acid uptake by bovine brain microvessel endothelial cells: role of active efflux transport 2004 ·Epilepsy Research ·John P. Gibbs, Moji Christianah Adeyeye, Ziping Yang, Danny D. Shen	50
16	Ibuprofen arginate provides effective relief from postoperative dental pain with a more rapid onset of action than ibuprofen 2002 ·European Journal of Clinical Pharmacology ·Paul J. Desjardins, Peter M. Black, Maria B Papageorge, (unknown), Danny D. Shen, (unknown), Alfredo Ardia	68
17	Intravenous morphine in postoperative infants: intermittent bolus dosing versus targeted continuous infusions 2000 ·Pain ·Anne M Lynn, Mary Kay Nespeca, Susan L. Bratton, Danny D. Shen	64
18	Effects of probenecid on brain-cerebrospinal fluid-blood distribution kinetics of E-Delta 2-valproic acid in rabbits. 1997 ·PubMed ·(unknown), Karen M. Powers, Alan A. Artru, (unknown), (unknown), Kimberly K. Adkison, Thomas F. Kalhorn, Danny D. Shen	11
19	Methods to reduce background interferences in electron-capture gas chromatographic analysis of valproic acid and its unsaturated metabolites after derivatization with pentafluorobenzyl bromide 1997 ·Journal of Chromatography B Biomedical Sciences and Applications ·Russell L. Dills, Danny D. Shen	15
20	Regioselectivity and Enantioselectivity of Metoprolol Oxidation by Two Variants of cDNA-Expressed P4502D6 1995 ·Pharmaceutical Research ·Douglas S. Mautz, Danny D. Shen, Wendel L. Nelson	7

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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