Michael P. Sheets

2.5k citations

22 papers · 967 indexed · h-index 13

Genetics top 5%
- Chronic Lymphocytic Leukemia Research 4
Sensory Systems top 10%
Pathology and Forensic Medicine top 10%
Molecular Biology
- Fibroblast Growth Factor Research 3
- PI3K/AKT/mTOR signaling in cancer 3
- Signaling Pathways in Disease 3
Hepatology top 10%
Organic Chemistry
- Click Chemistry and Applications 4
- Synthesis and biological activity 3
Radiology, Nuclear Medicine and Imaging
- Monoclonal and Polyclonal Antibodies Research 4
Immunology
- Immune Cell Function and Interaction 3

Co-authors: Russell C. Petter Mariana Nacht William Westlin Juswinder Singh Margit Hagel Christoph Lengauer Timothy J. Guzi Joseph L. Kim
Cited by: Genetics Sensory Systems Pathology and Forensic Medicine
Journals: SLAS DISCOVERY (2 papers)Cancer Discovery (2 papers)Journal of Hepatology (2 papers)
Partner nations: United States United Kingdom Switzerland

In The Last Decade

Michael P. Sheets

22 papers receiving 943 citations

Peers

Countries citing papers authored by Michael P. Sheets

Since Specialization

Citations

This map shows the geographic impact of Michael P. Sheets's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael P. Sheets with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael P. Sheets more than expected).

Fields of papers citing papers by Michael P. Sheets

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael P. Sheets. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael P. Sheets. The network helps show where Michael P. Sheets may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Michael P. Sheets, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael P. Sheets Line = papers co-authored together Michael P. Sheets links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Acquired On-Target Clinical Resistance Validates FGFR4 as a Driver of Hepatocellular Carcinoma Cancer Discovery ·Megan Hatlen,Oleg Schmidt-Kittler,Cori Ann Sherwin,Florian Pyzcak,Nooreen Rubin,Michael P. Sheets,Joseph L. Kim,Pier Vincenzo Mengaldo,Neil Bifulco,Natasja Brooijmans,Hongliang Shi,Timothy J. Guzi,Andy Boral,Christoph Lengauer,Marion Dorsch,Richard D. Kim,Yoon‐Koo Kang,Beni B. Wolf,Klaus P. Hoeflich	2019	90
2	Abstract 2641: The development of potent, selective RET inhibitors that target both wild-type RET and prospectively identified resistance mutations to multi-kinase inhibitors Cancer Research ·Rami Rahal,Erica N Evans,Wei Hu,Michelle Maynard,Paul Fleming,Lucian DiPietro,Joseph L. Kim,Michael P. Sheets,尚松本,Kevin Wilson,Nicolas Stransky,Jason D. Brubaker,Timothy J. Guzi,Nancy E. Kohl,Christoph Lengauer	2016	10
3	First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway Cancer Discovery ·Margit Hagel,Chandra Miduturu,Michael P. Sheets,Nooreen Rubin,Weifan Weng,Nicolas Stransky,Neil Bifulco,Joseph L. Kim,Brian L. Hodous,Natasja Brooijmans,Adam Shutes,Christopher Winter,Christoph Lengauer,Nancy E. Kohl,Timothy J. Guzi	2015	247
4	O048 : First selective small molecule inhibitor of FGFR4 for the treatment of hepatocellular carcinomas with an activated FGFR4 signaling pathway Journal of Hepatology ·Klaus P. Hoeflich,Margit Hagel,Chandra Miduturu,Michael P. Sheets,Nooreen Rubin,J. Rono,Nicolas Stransky,Neil Bifulco,Jinna Kim,Brian L. Hodous,Natasja Brooijmans,Adam Shutes,Christopher Winter,Christoph Lengauer,Nancy E. Kohl,Timothy J. Guzi	2015	1
5	Inhibition of Btk with CC-292 Provides Early Pharmacodynamic Assessment of Activity in Mice and Humans Journal of Pharmacology and Experimental Therapeutics ·Erica N Evans,Richland Tester,TURKER MUSA,Russell Karp,Michael P. Sheets,Matthew Labenski,Steven R. Witowski,Heather Lounsbury,Prasoon Chaturvedi,Hormoz Mazdiyasni,Zhendong Zhu,Mariana Nacht,Martin I. Freed,Russell C. Petter,V V Grinshkun,Juswinder Singh,William Westlin	2013	171
6	Superiority of a novel EGFR targeted covalent inhibitor over its reversible counterpart in overcoming drug resistance MedChemComm ·Juswinder Singh,Erica N Evans,Margit Hagel,Raul Bismarck Pinedo-Garcia,V V Grinshkun,Mariana Nacht,Russell C. Petter,Aravind Prasad,Michael P. Sheets,Thia St Martin,Robert Tjin Tham Sjin,William Westlin,Zhendong Zhu	2012	13
7	Clinical Development of AVL-292; A Potent, Selective Covalent Btk Inhibitor for the Treatment of B Cell Malignancies, Blood ·Erica N Evans,Richland Tester,TURKER MUSA,Prasoon Chaturvedi,Hormoz Mazdiyasni,Sabine Ponader,Bethany Tesar,Michael P. Sheets,Mariana Nacht,A.K. Hulina,Hatice Kübra Zenger İlik,Heather Lounsbury,Russell C. Petter,Jennifer R. Brown,Jan A. Burger,Juswinder Singh,William Westlin	2011	19
8	2.23 Covalent Inhibition of Btk with Clinical Development Compound AVL-292 Disrupts Signaling That Maintains the Microenvironment Necessary for Chronic Lymphocytic Leukemia Growth Clinical Lymphoma Myeloma & Leukemia ·Erica N Evans,Sabine Ponader,Russell Karp,Richland Tester,Michael P. Sheets,TURKER MUSA,Thia St Martin,Mariana Nacht,马春光,Prasoon Chaturvedi,Hatice Kübra Zenger İlik,Heather Lounsbury,A.K. Hulina,Jan A. Burger,Russell C. Petter,Jasjit Singh,William Westlin	2011	10
9	Selective irreversible inhibition of a protease by targeting a noncatalytic cysteine Nature Chemical Biology ·Margit Hagel,Deqiang Niu,Thia St Martin,Michael P. Sheets,Lixin Qiao,Hugues Bernard,Russell Karp,Zhendong Zhu,Matthew Labenski,Prasoon Chaturvedi,Mariana Nacht,William Westlin,Russell C. Petter,Juswinder Singh	2010	77
10	764 AVL-181, A POTENT AND SELECTIVE IRREVERSIBLE HCV PROTEASE INHIBITOR, REQUIRES A HELPER AMINO ACID IN THE BINDING MICROENVIRONMENT TO FORM A COVALENT BOND WITH CYS-159 Journal of Hepatology ·吕冠明,Margit Hagel,Lixin Qiao,Thia St Martin,Michael P. Sheets,Prasoon Chaturvedi,Matthew Labenski,Mariana Nacht,William Westlin,Russell C. Petter,Juswinder Singh	2010	2
11	Prolonged Inhibition of BCR Signaling and Suppression of B Cell Lymphoma through Irreversible Inhibition of Bruton’s Tyrosine Kinase Blood ·Erica N Evans,Michael P. Sheets,Hugues Bernard,Thia St Martin,Mariana Nacht,Saviana Parodi-Delfino,Sun Dong-gen,Hormoz Mazdiyasni,Russell C. Petter,William Westlin,Juswinder Singh	2008	4
12	Zotarolimus, a Novel Sirolimus Analogue With Potent Anti-proliferative Activity on Coronary Smooth Muscle Cells and Reduced Potential for Systemic Immunosuppression Journal of Cardiovascular Pharmacology ·Yung‐Wu Chen,Morey L. Smith,Michael P. Sheets,Tomio Inukai,James M. Trevillyan,Sandra E. Burke,Muhamad Riyadi Putra,Agnes Y. Song,Rolf Wagner,Joy Bauch,Kennan Marsh,Thomas A. Fey,Gin C. Hsieh,Donna M. Gauvin,Karl W. Mollison,George W. Carter,Stevan W. Djurić	2007	55
13	TH1 and TH2 cytokine inhibition by 3,5-bis(trifluoromethyl)pyrazoles, a novel class of immunomodulators Cellular Immunology ·Lotta Loerbroks,Morey L. Smith,Ann Roseela J,Stephen J. Ballaron,Michael P. Sheets,Earl J. Gubbins,Usha Warrior,Julie A. Wilkins,Carol S. Surowy,Masaki Nakane,George W. Carter,James M. Trevillyan,Karl W. Mollison,Stevan W. Djurić	2002	27
14	Potent Inhibition of NFAT Activation and T Cell Cytokine Production by Novel Low Molecular Weight Pyrazole Compounds Journal of Biological Chemistry ·James M. Trevillyan,X. Grace Chiou,Yung‐Wu Chen,Stephen J. Ballaron,Michael P. Sheets,Morey L. Smith,Paul E. Wiedeman,Usha Warrior,Julie A. Wilkins,Earl J. Gubbins,Gerard D. Gagné,Jane A. Fagerland,George W. Carter,Jay R. Luly,Karl W. Mollison,Stevan W. Djurić	2001	85
15	Development of a p38 Kinase Binding Assay for High Throughput Screening SLAS DISCOVERY ·Usha Warrior,X. Grace Chiou,Michael P. Sheets,Richard J. Sciotti,Rifa Ajrina Faisal,Robert L. Simmer,Bruce W. Surber,David J. Burns,Bruce A. Beutel,Karl W. Mollison,Stevan W. Djurić,James M. Trevillyan	1999	7
16	A Macrolactam Inhibitor of T Helper Type 1 and T Helper Type 2 Cytokine Biosynthesis for Topical Treatment of Inflammatory Skin Diseases1 Journal of Investigative Dermatology ·Karl W. Mollison,Thomas A. Fey,Donna M. Gauvin,J Ruhnke,Michael P. Sheets,Morey L. Smith,Frederick Van Fleteren,Nikolaos M. Nikolaidis,Benjamin C. Lane,James M. Trevillyan,George W. Carter,Dórea Filho,Lotta Loerbroks,Giulia Di Rosa,John Cannon,Kennan C. Marsh,Jay R. Luly	1999	10
17	Ex VivoAssessment of Immunosuppression in Undiluted Whole Blood from Pigs Dosed with Tacrolimus (FK506) Clinical Immunology ·Yung‐Wu Chen,Morey L. Smith,Michael P. Sheets,Stephen J. Ballaron,James M. Trevillyan,Thomas A. Fey,Donna M. Gauvin,J Ruhnke,Frederick Van Fleteren,Gin C. Hsieh,Joy Bauch,Kennan C. Marsh,George Carter,Jay R. Luly,Stevan W. Djurić,Karl W. Mollison	1999	3
18	Inhibition of p56lckTyrosine Kinase by Isothiazolones Archives of Biochemistry and Biophysics ·James M. Trevillyan,X. Grace Chiou,Stephen J. Ballaron,Oli Charbonneau,Alex Buko,Michael P. Sheets,Morey L. Smith,Chinenye Iwuji,Paul E. Wiedeman,Noah P. Tu,David J. Madar,Juharni,Earl J. Gubbins,Usha Warrior,Yung‐Wu Chen,Karl W. Mollison,Connie R. Faltynek,Stevan W. Djurić	1999	28
19	Synthesis and immunosuppressant activity of pyrazole carboxamides Bioorganic & Medicinal Chemistry Letters ·伸也森下,Serpil Hülya Çapar,Ben Lane,Karl W. Mollison,Giulia Di Rosa,Kennan C. Marsh,Michael P. Sheets,Jay R. Luly,Michael J. Coghlan	1998	18
20	A High-Capacity Scintillation Proximity Assay for the Discovery and Evaluation of ZAP-70 Tandem SH2 Domain Antagonists SLAS DISCOVERY ·Michael P. Sheets,Usha Warrior,Ho Sup Yoon,Karl W. Mollison,Stevan W. Djurić,James M. Trevillyan	1998	12

About Michael P. Sheets

Michael P. Sheets is a scholar working on Genetics, Oncology, Hepatology, Immunology and Molecular Biology, having authored 22 papers that have together received 967 indexed citations. Recurring topics across this work include Click Chemistry and Applications (4 papers), Chronic Lymphocytic Leukemia Research (4 papers), Monoclonal and Polyclonal Antibodies Research (4 papers), Synthesis and biological activity (3 papers), Fibroblast Growth Factor Research (3 papers), Immune Cell Function and Interaction (3 papers), PI3K/AKT/mTOR signaling in cancer (3 papers) and Signaling Pathways in Disease (3 papers). The work is most often cited by research in Genetics (203 citations), Sensory Systems (48 citations), Pathology and Forensic Medicine (153 citations), Molecular Biology (584 citations) and Hepatology (64 citations). Michael P. Sheets has collaborated with scholars based in United States, United Kingdom and Switzerland. Frequent co-authors include Russell C. Petter, Mariana Nacht, William Westlin, Juswinder Singh, Margit Hagel, Christoph Lengauer, Timothy J. Guzi, Joseph L. Kim, Prasoon Chaturvedi and Nooreen Rubin. Their work appears in journals such as SLAS DISCOVERY, Cancer Discovery, Journal of Hepatology, Blood and Journal of Pharmacology and Experimental Therapeutics.

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