Regine S. Bohacek

4.0k citations

49 papers · 2.6k indexed · 1 hit paper · h-index 23

Computational Theory and Mathematics top 0.5%
- Computational Drug Discovery Methods 9
Organic Chemistry top 2%
- Click Chemistry and Applications 7
Molecular Biology top 5%
- Chemical Synthesis and Analysis 14
- Protein Kinase Regulation and GTPase Signaling 10
- Biochemical and Structural Characterization 8
- Protein Structure and Dynamics 5
- Protein Tyrosine Phosphatases 5
Hematology top 5%
Genetics top 5%
Oncology
- Peptidase Inhibition and Analysis 6

Co-authors: Colin McMartin Wayne C. Guida Tomi K. Sawyer William C. Shakespeare David C. Dalgarno Daniel H. Rich Chester A. Metcalf Amy S. Ripka
Cited by: Computational Theory and Mathematics Organic Chemistry Molecular Biology
Journals: Bioorganic & Medicinal Chemistry Letters (7 papers)Journal of Medicinal Chemistry (7 papers)Journal of the American Chemical Society (2 papers)
Partner nations: United States Switzerland Canada

In The Last Decade

Regine S. Bohacek

48 papers receiving 2.4k citations

Hit Papers

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Peers

Countries citing papers authored by Regine S. Bohacek

Since Specialization

Citations

This map shows the geographic impact of Regine S. Bohacek's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Regine S. Bohacek with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Regine S. Bohacek more than expected).

Fields of papers citing papers by Regine S. Bohacek

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Regine S. Bohacek. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Regine S. Bohacek. The network helps show where Regine S. Bohacek may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Regine S. Bohacek, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Regine S. Bohacek Line = papers co-authored together Regine S. Bohacek links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Novel therapeutic candidates, identified by molecular modeling, induce γ-globin gene expression in vivo Blood Cells Molecules and Diseases ·Michael S. Boosalis,Serguei A. Castañeda,Marie Trudel,Rodwell Mabaera,Gary L. White,Christopher H. Lowrey,David W. Emery,F. Padilla,Ling Shen,William A. Wargin,Regine S. Bohacek,Douglas V. Faller,Susan P. Perrine	2011	15
2	Identification of Novel Small‐molecule Inducers of Fetal Hemoglobin Using Pharmacophore and ‘PSEUDO’ Receptor Models Chemical Biology & Drug Design ·Regine S. Bohacek,Michael S. Boosalis,Colin McMartin,Douglas V. Faller,Susan P. Perrine	2006	20
3	Structural Basis of Src Tyrosine Kinase Inhibition with a New Class of Potent and Selective Trisubstituted Purine‐based Compounds Chemical Biology & Drug Design ·David C. Dalgarno,Thilo Stehle,Surinder S. Narula,P. Schelling,Marie Rose van Schravendijk,Susan Adams,Lawrence Andrade,Jeff Keats,Mary K. Ram,Lei Jin,Trudy H. Grossman,Ian A. MacNeil,Chester A. Metcalf,William C. Shakespeare,Yihan Wang,E. N. Monteiro,Raji Sundaramoorthi,Regine S. Bohacek,Manfred Weigele,Tomi K. Sawyer	2005	65
4	Structure-based design of AP23573, a phosphorus-containing analog of rapamycin for anti-tumor therapy. Cancer Research ·Chester A. Metcalf,Regine S. Bohacek,Leonard W. Rozamus,Олексій Михайлович Сітков,B Lima-santana,Victor M. Rivera,Hao Tang,Jeffrey Keats,David C. Dalgarno,J. T. Snodgrass,J. Holmen,Manfred Weigele,Tim Clackson	2004	19
5	Bone-Targeted Src kinase inhibitors: novel pyrrolo- and pyrazolopyrimidine analogues Bioorganic & Medicinal Chemistry Letters ·Raji Sundaramoorthi,William C. Shakespeare,Terence P. Keenan,Chester A. Metcalf,Yihan Wang,G. Rosenbaum,J W Hadfield,Shuangying Liu,Regine S. Bohacek,Surinder S. Narula,David C. Dalgarno,YuanzongLai,Wentao Niu,Shuenn Liou,Susan Adams,Mary K. Ram,Jeffrey Keats,Manfred Weigele,Tomi K. Sawyer	2003	14
6	Src Homology-2 Inhibitors: Peptidomimetic and Nonpeptide Mini-Reviews in Medicinal Chemistry ·Tomi K. Sawyer,Regine S. Bohacek,David C. Dalgarno,Charles J. Eyermann,Agnieszka Nowinska,Chester A. Metcalf,William C. Shakespeare,Raji Sundaramoorthi,Yihan Wang,Michael G. Yang	2002	42
7	A novel phosphotyrosine mimetic 4′-carboxymethyloxy-3′-phosphonophenylalanine (cpp): exploitation in the design of nonpeptide inhibitors of pp60Src SH2 domain Bioorganic & Medicinal Chemistry Letters ·Agnieszka Nowinska,Michael G. Yang,George P. Luke,William C. Shakespeare,Raji Sundaramoorthi,Yihan Wang,D. T. Johnson,Amir Hadizadeh,Shelia M. Violette,Wei Guan,Catherine Bartlett,Jeremy A. Smith,Marcos Hatada,Xiaode Lu,David C. Dalgarno,Charles J. Eyermann,Regine S. Bohacek,Tomi K. Sawyer	2001	16
8	A Src SH2 selective binding compound inhibits osteoclast-mediated resorption Chemistry & Biology ·Shelia M. Violette,William C. Shakespeare,Catherine Bartlett,Wei Guan,Jeremy A. Smith,Richard J. Rickles,Regine S. Bohacek,Dennis A. Holt,Roland Baron,Tomi K. Sawyer	2000	47
9	Exploring the Universe of Organic Molecules for Potent New Drugs TechConnect Briefs ·Regine S. Bohacek,Peter W. Glunz,Colin McMartin,D. H. RICH,Yingguo Fang	1999	0
10	Structure-based design and synthesis of a novel class of Src SH2 inhibitors Bioorganic & Medicinal Chemistry Letters ·John L. Buchanan,Regine S. Bohacek,George P. Luke,Marcos Hatada,Xiaode Lu,David C. Dalgarno,Surinder S. Narula,Cara Byrne,Dennis A. Holt	1999	23
11	An efficient synthesis of a 4′-phosphonodifluoromethyl-3′-formyl-phenylalanine containing Src SH2 ligand Bioorganic & Medicinal Chemistry Letters ·William C. Shakespeare,Regine S. Bohacek,Surinder S. Narula,Mihai Azimioara,Yang-Yi Fan,David C. Dalgarno,Hyeri Ahn,Martyn C. Botfield,Dennis A. Holt	1999	10
12	Synthesis of novel cyclic protease inhibitors using Grubbs olefin metathesis Bioorganic & Medicinal Chemistry Letters ·Amy S. Ripka,Regine S. Bohacek,Daniel H. Rich	1998	56
13	QXP: Powerful, rapid computer algorithms for structure-based drug design Journal of Computer-Aided Molecular Design ·Colin McMartin,Regine S. Bohacek	1997	414
14	Modern computational chemistry and drug discovery: structure generating programs Current Opinion in Chemical Biology ·Regine S. Bohacek,Colin McMartin	1997	26
15	The art and practice of structure-based drug design: A molecular modeling perspectivebreakdown → Medicinal Research Reviews ·Regine S. Bohacek,Colin McMartin,Wayne C. Guida	1996	753
16	Exploring the universe of molecules for new drugs Nature Medicine ·Regine S. Bohacek,Colin McMartin	1995	4
17	Flexible matching of test ligands to a 3D pharmacophore using a molecular superposition force field: Comparison of predicted and experimental conformations of inhibitors of three enzymes Journal of Computer-Aided Molecular Design ·Colin McMartin,Regine S. Bohacek	1995	34
18	Solvent effects on the conformation of cyclo(‐D‐Trp‐D‐Asp‐Pro‐D‐val‐Leu‐) An NMR spectroscopy and molecular modeling study International journal of peptide & protein research ·Nina C. Gonnella,Xiaolu Zhang,Yong Jin,Om Prakash,C. Paris,István Kolossváry,Wayne C. Guida,Regine S. Bohacek,Isidoros Vlattas,Hariharan Subramani	1994	11
19	Definition and display of steric, hydrophobic, and hydrogen bonding properties of ligand binding sites in proteins using Lee and Richards accessible surface: validation of a high-resolution graphical tool for drug design Journal of Medicinal Chemistry ·Regine S. Bohacek,Colin McMartin	1992	92
20	A rapid method for the computation, comparison and display of molecular volumes Journal of Molecular Graphics ·Regine S. Bohacek,Wayne C. Guida	1989	8

About Regine S. Bohacek

Regine S. Bohacek is a scholar working on Computational Theory and Mathematics, Molecular Biology, Organic Chemistry, Genetics and Oncology, having authored 49 papers that have together received 2.6k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (14 papers), Protein Kinase Regulation and GTPase Signaling (10 papers), Computational Drug Discovery Methods (9 papers), Biochemical and Structural Characterization (8 papers), Click Chemistry and Applications (7 papers), Peptidase Inhibition and Analysis (6 papers), Protein Structure and Dynamics (5 papers) and Protein Tyrosine Phosphatases (5 papers). The work is most often cited by research in Computational Theory and Mathematics (975 citations), Organic Chemistry (800 citations), Molecular Biology (1.6k citations), Hematology (263 citations) and Genetics (227 citations). Regine S. Bohacek has collaborated with scholars based in United States, Switzerland and Canada. Frequent co-authors include Colin McMartin, Wayne C. Guida, Tomi K. Sawyer, William C. Shakespeare, David C. Dalgarno, Daniel H. Rich, Chester A. Metcalf, Amy S. Ripka, Raji Sundaramoorthi and Yihan Wang. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Journal of the American Chemical Society, Organic Letters and Medicinal Research Reviews.

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