Frank Madeo

69.7k total citations · 10 hit papers
203 papers, 23.5k citations indexed

About

Frank Madeo is a scholar working on Molecular Biology, Epidemiology and Cell Biology. According to data from OpenAlex, Frank Madeo has authored 203 papers receiving a total of 23.5k indexed citations (citations by other indexed papers that have themselves been cited), including 131 papers in Molecular Biology, 62 papers in Epidemiology and 36 papers in Cell Biology. Recurrent topics in Frank Madeo's work include Autophagy in Disease and Therapy (61 papers), Fungal and yeast genetics research (35 papers) and Polyamine Metabolism and Applications (35 papers). Frank Madeo is often cited by papers focused on Autophagy in Disease and Therapy (61 papers), Fungal and yeast genetics research (35 papers) and Polyamine Metabolism and Applications (35 papers). Frank Madeo collaborates with scholars based in Austria, France and Germany. Frank Madeo's co-authors include Guido Kroemer, Didac Carmona‐Gutiérrez, Tobias Eisenberg, Kai‐Uwe Fröhlich, Federico Pietrocola, Lorenzo Galluzzi, Sabrina Büttner, Stephan J. Sigrist, Eleonore Fröhlich and Silke Wissing and has published in prestigious journals such as Science, Cell and Journal of Biological Chemistry.

In The Last Decade

Frank Madeo

199 papers receiving 23.2k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Acetyl Coenzyme A: A Central Metabolite and Second Messenger

2015 995 citations Federico Pietrocola, Lorenzo Galluzzi et al. profile →
FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling

2012 872 citations Frank Madeo et al. profile →
Oxygen Stress: A Regulator of Apoptosis in Yeast

1999 869 citations Frank Madeo, Stephan J. Sigrist et al. profile →
Spermidine in health and disease

2018 747 citations Frank Madeo, Tobias Eisenberg et al. Science profile →
A Caspase-Related Protease Regulates Apoptosis in Yeast

2002 729 citations Frank Madeo, Stephan J. Sigrist et al. profile →
Mechanisms of pre‐apoptotic calreticulin exposure in immunogenic cell death

2009 688 citations Nicholas Joza, Frank Madeo et al. profile →
A Yeast Mutant Showing Diagnostic Markers of Early and Late Apoptosis

1997 665 citations Frank Madeo, Kai‐Uwe Fröhlich et al. profile →
Metabolic Control of Longevity

2016 523 citations Carlos López-Otı́n, Lorenzo Galluzzi et al. profile →
Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential

2019 432 citations Frank Madeo, Didac Carmona‐Gutiérrez et al. profile →
Cytosolic lipolysis and lipophagy: two sides of the same coin

2017 400 citations Frank Madeo et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Frank Madeo	14.8k	5.0k	3.7k	3.0k	2.5k	203	23.5k
Tilman Grune	12.4k 0.8×	3.4k 0.7×	6.0k 1.6×	4.3k 1.5×	1.2k 0.5×	474	26.0k
Nektarios Tavernarakis	9.7k 0.7×	6.1k 1.2×	3.4k 0.9×	2.1k 0.7×	3.4k 1.4×	240	18.3k
Reuben J. Shaw	20.6k 1.4×	7.6k 1.5×	5.1k 1.4×	2.7k 0.9×	1.1k 0.4×	85	30.3k
Andrew Dillin	13.1k 0.9×	4.7k 0.9×	5.0k 1.4×	4.7k 1.6×	7.4k 3.0×	124	21.9k
Rosario Rizzuto	31.6k 2.1×	6.2k 1.2×	6.1k 1.7×	8.0k 2.7×	690 0.3×	312	42.9k
Domenico Accili	18.8k 1.3×	4.7k 0.9×	7.8k 2.1×	2.1k 0.7×	1.5k 0.6×	271	31.5k
Ulf T. Brunk	9.0k 0.6×	4.2k 0.8×	3.4k 0.9×	2.1k 0.7×	1.0k 0.4×	253	18.2k
Kai Kaarniranta	10.0k 0.7×	3.7k 0.7×	3.6k 1.0×	1.5k 0.5×	803 0.3×	371	21.0k
Vilhelm A. Bohr	30.2k 2.0×	3.9k 0.8×	8.0k 2.2×	1.7k 0.6×	2.3k 0.9×	539	42.0k
Dale E. Bredesen	16.6k 1.1×	3.7k 0.7×	5.2k 1.4×	4.2k 1.4×	412 0.2×	232	28.9k

Countries citing papers authored by Frank Madeo

Since Specialization

Citations

This map shows the geographic impact of Frank Madeo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank Madeo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank Madeo more than expected).

Fields of papers citing papers by Frank Madeo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank Madeo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank Madeo. The network helps show where Frank Madeo may publish in the future.

Co-authorship network of co-authors of Frank Madeo

This figure shows the co-authorship network connecting the top 25 collaborators of Frank Madeo. A scholar is included among the top collaborators of Frank Madeo based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frank Madeo. Frank Madeo is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Knittelfelder, Oskar, Helmut Jungwirth, Gerald N. Rechberger, et al.. (2025). Sugar accelerates chronological aging in yeast via ceramides. PubMed. 9. 158–173.

Montégut, Léa, Mahmoud Abdellatif, Omar Motiño, et al.. (2023). Acyl coenzyme A binding protein (ACBP): An aging‐ and disease‐relevant “autophagy checkpoint”. Aging Cell. 22(9). e13910–e13910. 23 indexed citations

Zimmermann, Andreas, Frank Madeo, Abhinav Diwan, et al.. (2023). Metabolic control of mitophagy. European Journal of Clinical Investigation. 54(4). e14138–e14138. 19 indexed citations

Montégut, Léa, Adrien Joseph, Hui Chen, et al.. (2022). DBI/ACBP is a targetable autophagy checkpoint involved in aging and cardiovascular disease. Autophagy. 19(7). 2166–2169. 14 indexed citations

Liang, YongTian, Christine B. Beuschel, Laxmikanth Kollipara, et al.. (2021). eIF5A hypusination, boosted by dietary spermidine, protects from premature brain aging and mitochondrial dysfunction. Cell Reports. 35(2). 108941–108941. 79 indexed citations

Wirth, Miranka, Claudia Schwarz, Gloria Benson, et al.. (2019). Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)—study protocol for a randomized controlled trial. Alzheimer s Research & Therapy. 11(1). 36–36. 78 indexed citations

Madeo, Frank, Tobias Eisenberg, Federico Pietrocola, & Guido Kroemer. (2018). Spermidine in health and disease. Science. 359(6374). 747 indexed citations breakdown →

Madeo, Frank, Andreas Zimmermann, Maria Chiara Maiuri, & Guido Kroemer. (2015). Essential role for autophagy in life span extension. Journal of Clinical Investigation. 125(1). 85–93. 321 indexed citations

Vos, Ann De, Julia Ring, Frank Madeo, et al.. (2015). The peptidyl prolyl cis/trans isomerase Pin1/Ess1 inhibits phosphorylation and toxicity of tau in a yeast model for Alzheimer’s disease. SHILAP Revista de lepidopterología. 2(2). 144–160. 8 indexed citations

10.

Niso‐Santano, Mireia, José Manuel Bravo‐San Pedro, Maria Chiara Maiuri, et al.. (2015). Novel inducers of BECN1-independent autophagy:cis-unsaturated fatty acids. Autophagy. 11(3). 575–577. 13 indexed citations

11.

Schroeder, Sabrina, Tobias Pendl, Andreas Zimmermann, et al.. (2014). Acetyl-coenzyme A. Autophagy. 10(7). 1335–1337. 38 indexed citations

12.

Dengjel, Jörn, Maria Høyer-Hansen, Tobias Eisenberg, et al.. (2012). Identification of Autophagosome-associated Proteins and Regulators by Quantitative Proteomic Analysis and Genetic Screens. Molecular & Cellular Proteomics. 11(3). M111.014035–M111.014035. 114 indexed citations

13.

Galluzzi, Lorenzo, Ilio Vitale, Laura Senovilla, et al.. (2012). Independent transcriptional reprogramming and apoptosis induction by cisplatin. Cell Cycle. 11(18). 3472–3480. 24 indexed citations

14.

Mariño, Guillermo, Frank Madeo, & Guido Kroemer. (2010). Autophagy for tissue homeostasis and neuroprotection. Current Opinion in Cell Biology. 23(2). 198–206. 166 indexed citations

15.

Madeo, Frank, Tobias Eisenberg, Sabrina Büttner, Christoph Ruckenstuhl, & Guido Kroemer. (2010). Spermidine: A novel autophagy inducer and longevity elixir. Autophagy. 6(1). 160–162. 143 indexed citations

16.

Heeren, Gino, Mark Rinnerthaler, H. Klinger, et al.. (2009). The mitochondrial ribosomal of the large subunit, afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1. ISBN. 622–636. 1 indexed citations

17.

Heeren, Gino, Mark Rinnerthaler, Peter Laun, et al.. (2009). The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1. Aging. 1(7). 622–636. 70 indexed citations

18.

Galluzzi, Lorenzo, Nicholas Joza, Ezgi Tasdemir, et al.. (2008). No death without life: vital functions of apoptotic effectors. Cell Death and Differentiation. 15(7). 1113–1123. 206 indexed citations

19.

Lepperdinger, Günter, Peter Berger, Michael Breitenbach, et al.. (2008). The use of genetically engineered model systems for research on human aging. ISBN. 1 indexed citations

20.

Rockenfeller, Patrick & Frank Madeo. (2008). Apoptotic death of ageing yeast. Experimental Gerontology. 43(10). 876–881. 74 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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