Tony Tiganis

11.5k total citations · 2 hit papers
118 papers, 8.8k citations indexed

About

Tony Tiganis is a scholar working on Molecular Biology, Immunology and Physiology. According to data from OpenAlex, Tony Tiganis has authored 118 papers receiving a total of 8.8k indexed citations (citations by other indexed papers that have themselves been cited), including 82 papers in Molecular Biology, 48 papers in Immunology and 22 papers in Physiology. Recurrent topics in Tony Tiganis's work include Protein Tyrosine Phosphatases (52 papers), Galectins and Cancer Biology (31 papers) and Adipose Tissue and Metabolism (19 papers). Tony Tiganis is often cited by papers focused on Protein Tyrosine Phosphatases (52 papers), Galectins and Cancer Biology (31 papers) and Adipose Tissue and Metabolism (19 papers). Tony Tiganis collaborates with scholars based in Australia, United States and Canada. Tony Tiganis's co-authors include Nicholas K. Tonks, Andrew Flint, Bruce E. Kemp, Florian Wiede, Garron T. Dodd, Anton M. Bennett, David Barford, Sandra Galić, Belinda J. Michell and Zhong‐Yin Zhang and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Tony Tiganis

116 papers receiving 8.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Development of “substrate-trapping” mutants to identify physiological substrates of protein tyrosine phosphatases

1997 661 citations Tony Tiganis, Nicholas K. Tonks et al. profile →
Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC

2018 280 citations Florian Wiede, Garron T. Dodd et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Tony Tiganis Australia	52	5.4k	2.7k	1.8k	1.3k	893	118	8.8k
Yehiel Zick Israel	48	6.1k 1.1×	1.8k 0.7×	1.8k 1.0×	654 0.5×	835 0.9×	124	9.5k
Xiao‐Jian Sun United States	51	8.1k 1.5×	1.1k 0.4×	1.7k 0.9×	1.4k 1.1×	872 1.0×	127	11.4k
Andrea Graziani Italy	34	3.9k 0.7×	907 0.3×	1.3k 0.7×	999 0.8×	509 0.6×	97	7.3k
Jay H. Chung United States	34	5.1k 0.9×	774 0.3×	1.5k 0.8×	1.1k 0.9×	824 0.9×	73	7.7k
Anton M. Bennett United States	42	5.3k 1.0×	1.6k 0.6×	644 0.4×	857 0.7×	535 0.6×	97	6.9k
Jack van Horssen Netherlands	58	4.2k 0.8×	2.0k 0.7×	1.5k 0.8×	925 0.7×	447 0.5×	116	10.2k
Tamera Barrett United States	28	7.0k 1.3×	1.6k 0.6×	1.2k 0.7×	1.8k 1.4×	915 1.0×	28	9.9k
Derek Yang United States	25	4.7k 0.9×	1.5k 0.6×	567 0.3×	1.2k 0.9×	466 0.5×	40	7.4k
Fumikazu Okajima Japan	59	7.1k 1.3×	1.2k 0.4×	1.6k 0.9×	569 0.5×	451 0.5×	197	9.9k
Ana Cuenda Spain	43	7.9k 1.4×	1.9k 0.7×	1.3k 0.7×	2.1k 1.7×	516 0.6×	76	11.5k

Countries citing papers authored by Tony Tiganis

Since Specialization

Citations

This map shows the geographic impact of Tony Tiganis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tony Tiganis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tony Tiganis more than expected).

Fields of papers citing papers by Tony Tiganis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tony Tiganis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tony Tiganis. The network helps show where Tony Tiganis may publish in the future.

Co-authorship network of co-authors of Tony Tiganis

This figure shows the co-authorship network connecting the top 25 collaborators of Tony Tiganis. A scholar is included among the top collaborators of Tony Tiganis based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Tony Tiganis. Tony Tiganis is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Tiganis, Tony & Nicholas K. Tonks. (2025). Mechanisms, functions and therapeutic targeting of protein tyrosine phosphatases. Nature Reviews Molecular Cell Biology. 27(2). 129–152. 1 indexed citations

Du, Xin, Pei Kee Goh, Chenkai Ma, et al.. (2025). Targeting PTPN2 enhances human CAR T cell efficacy and the development of long-term memory in mouse xenograft models. Science Translational Medicine. 17(822). eadk0627–eadk0627.

Fernández‐Tussy, Pablo, Magdalena P. Cardelo, Hanming Zhang, et al.. (2024). miR-33 deletion in hepatocytes attenuates MASLD-MASH-HCC progression. JCI Insight. 9(19). 10 indexed citations

Bennett, Anton M. & Tony Tiganis. (2024). Protein Tyrosine Phosphatases in Metabolism: A New Frontier for Therapeutics. Annual Review of Physiology. 87(1). 301–324. 3 indexed citations

Kaur, Supreet, Chrysovalantou E. Xirouchaki, Pei Kee Goh, et al.. (2023). Mitochondria- and NOX4-dependent antioxidant defense mitigates progression to nonalcoholic steatohepatitis in obesity. Journal of Clinical Investigation. 134(3). 25 indexed citations

Goh, Pei Kee, Florian Wiede, Mara N. Zeissig, et al.. (2022). PTPN2 elicits cell autonomous and non–cell autonomous effects on antitumor immunity in triple-negative breast cancer. Science Advances. 8(8). eabk3338–eabk3338. 34 indexed citations

Charnley, Mirren, Andrea Newbold, Florian Wiede, et al.. (2022). Stepwise progression of β-selection during T cell development involves histone deacetylation. Life Science Alliance. 6(1). e202201645–e202201645. 2 indexed citations

Wiede, Florian, Kun‐Hui Lu, Xin Du, et al.. (2021). PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity. Cancer Discovery. 12(3). 752–773. 90 indexed citations

Willoughby, Lee, et al.. (2021). PTP61F Mediates Cell Competition and Mitigates Tumorigenesis. International Journal of Molecular Sciences. 22(23). 12732–12732. 5 indexed citations

10.

Xirouchaki, Chrysovalantou E., Yaoyao Jia, Meagan J. McGrath, et al.. (2021). Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance. Science Advances. 7(51). eabl4988–eabl4988. 66 indexed citations

11.

Yip, Hon Yan Kelvin, Annabel Chee, Ching‐Seng Ang, et al.. (2020). Control of Glucocorticoid Receptor Levels by PTEN Establishes a Failsafe Mechanism for Tumor Suppression. Molecular Cell. 80(2). 279–295.e8. 17 indexed citations

12.

Wiede, Florian, Kun‐Hui Lu, Xin Du, et al.. (2019). PTPN 2 phosphatase deletion in T cells promotes anti‐tumour immunity and CAR T‐cell efficacy in solid tumours. The EMBO Journal. 39(2). e103637–e103637. 92 indexed citations

13.

Wiede, Florian, Thomas C. Brodnicki, Pei Kee Goh, et al.. (2019). T-Cell–Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities. Diabetes. 68(6). 1251–1266. 38 indexed citations

14.

Koyama, Takashi, Travis K. Johnson, James C. Whisstock, et al.. (2018). Torso-Like Is a Component of the Hemolymph and Regulates the Insulin Signaling Pathway in Drosophila. Genetics. 208(4). 1523–1533. 8 indexed citations

15.

Kyriakou, Eleni, Stefanie Schmidt, Garron T. Dodd, et al.. (2018). Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus. Journal of Medicinal Chemistry. 61(24). 11144–11157. 60 indexed citations

16.

Pfuhlmann, Katrin, Sonja C. Schriever, Peter Baumann, et al.. (2018). Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1. Diabetes. 67(11). 2456–2465. 37 indexed citations

17.

Berry, Richard, Lars Kjer‐Nielsen, Matthew A. Perugini, et al.. (2012). The structural basis for autonomous dimerization of the pre-T-cell antigen receptor. Queensland's institutional digital repository (The University of Queensland). 9 indexed citations

18.

Ivetac, Ivan, Rajendra Gurung, Sandra Hakim, et al.. (2009). Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4‐phosphatase‐1. EMBO Reports. 10(5). 487–493. 62 indexed citations

19.

Shimizu, Takatsune, Yoshitaka Miyakawa, Satoshi Iwata, et al.. (2004). A novel mechanism for imatinib mesylate (STI571) resistance in CML cell line KT-1: role of TC-PTP in modulating signals downstream from the BCR-ABL fusion protein. Experimental Hematology. 32(11). 1057–1063. 23 indexed citations

20.

Price, John T., Tony Tiganis, Anika Agarwal, Daniel Djakiew, & Erik W. Thompson. (1999). Epidermal growth factor promotes MDA-MB-231 breast cancer cell migration through a phosphatidylinositol 3'-kinase and phospholipase C-dependent mechanism.. QUT ePrints (Queensland University of Technology). 59(21). 5475–8. 199 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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