John D. Lambris

62.4k total citations · 15 hit papers
570 papers, 47.8k citations indexed

About

John D. Lambris is a scholar working on Immunology, Hematology and Molecular Biology. According to data from OpenAlex, John D. Lambris has authored 570 papers receiving a total of 47.8k indexed citations (citations by other indexed papers that have themselves been cited), including 417 papers in Immunology, 130 papers in Hematology and 118 papers in Molecular Biology. Recurrent topics in John D. Lambris's work include Complement system in diseases (317 papers), Monoclonal and Polyclonal Antibodies Research (79 papers) and Blood groups and transfusion (51 papers). John D. Lambris is often cited by papers focused on Complement system in diseases (317 papers), Monoclonal and Polyclonal Antibodies Research (79 papers) and Blood groups and transfusion (51 papers). John D. Lambris collaborates with scholars based in United States, Germany and Greece. John D. Lambris's co-authors include Daniel Ricklin, George Hajishengallis, Dimitrios C. Mastellos, Maciej M. Markiewski, Kun Yang, Edimara S. Reis, Arvind Sahu, Bo Nilsson, Markus Huber‐Lang and Tom Eirik Mollnes and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

John D. Lambris

562 papers receiving 46.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Complement: a key system for immune surveillance and homeostasis

2010 2.8k citations Daniel Ricklin, George Hajishengallis et al. profile →
The Classical Complement Cascade Mediates CNS Synapse Elimination

2007 2.4k citations John D. Lambris et al. profile →
Low-Abundance Biofilm Species Orchestrates Inflammatory Periodontal Disease through the Commensal Microbiota and Complement

2011 903 citations George Hajishengallis, John D. Lambris et al. profile →
Generation of C5a in the absence of C3: a new complement activation pathway

2006 776 citations Markus Huber‐Lang, J. Vidya Sarma et al. profile →
Modulation of the antitumor immune response by complement

2008 598 citations Maciej M. Markiewski, Robert A. DeAngelis et al. profile →
Complement evasion by human pathogens

2008 573 citations John D. Lambris, Daniel Ricklin et al. profile →
Molecular Intercommunication between the Complement and Coagulation Systems

2010 571 citations Bo Nilsson, John D. Lambris et al. The Journal of Immunology profile →
Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

2020 545 citations Dimitrios C. Mastellos, John D. Lambris et al. Journal of Clinical Investigation profile →
The complement system in teleosts

2002 538 citations John D. Lambris et al. profile →
Drusen complement components C3a and C5a promote choroidal neovascularization

2006 531 citations J. Vidya Sarma, John D. Lambris et al. Proceedings of the National Academy of Sciences profile →
The Role of Complement in Inflammatory Diseases From Behind the Scenes into the Spotlight

2007 525 citations Maciej M. Markiewski, John D. Lambris profile →
Complement in disease: a defence system turning offensive

2016 410 citations Daniel Ricklin, Edimara S. Reis et al. profile →
Innate immune responses to trauma

2018 391 citations Markus Huber‐Lang, John D. Lambris et al. profile →
Current understanding of periodontal disease pathogenesis and targets for host‐modulation therapy

2020 299 citations George Hajishengallis, John D. Lambris et al. profile →
A guide to complement biology, pathology and therapeutic opportunity

2023 135 citations Dimitrios C. Mastellos, George Hajishengallis et al. profile →

Peers

Countries citing papers authored by John D. Lambris

Since Specialization

Citations

This map shows the geographic impact of John D. Lambris's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John D. Lambris with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John D. Lambris more than expected).

Fields of papers citing papers by John D. Lambris

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John D. Lambris. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John D. Lambris. The network helps show where John D. Lambris may publish in the future.

Co-authorship network of co-authors of John D. Lambris

This figure shows the co-authorship network connecting the top 25 collaborators of John D. Lambris. A scholar is included among the top collaborators of John D. Lambris based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John D. Lambris. John D. Lambris is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	The role of intracellular and cell-autonomous C3 in NF-κB priming in human macrophages 2025 ·Immunobiology ·(unknown), (unknown), Harald Husebye, Terje Espevik, Liv Ryan, Tom Eirik Mollnes, John D. Lambris, Trude Helen Flo	0
2	In vitro evaluation of iron oxide nanoparticle-induced thromboinflammatory response using a combined human whole blood and endothelial cell model 2023 ·Frontiers in Immunology ·Alexandra Gerogianni, (unknown), Camilla Mohlin, Trent M. Woodruff, John D. Lambris, Tom Eirik Mollnes, (unknown), Per H. Nilsson	12
3	Complement‐targeted therapeutics: An emerging field enabled by academic drug discovery 2023 ·American Journal of Hematology ·Christina Lamers, Daniel Ricklin, John D. Lambris	18
4	Complement Is Required for Microbe-Driven Induction of Th17 and Periodontitis 2022 ·The Journal of Immunology ·Hui Wang, (unknown), Tetsuhiro Kajikawa, Dimitrios C. Mastellos, John D. Lambris, George Hajishengallis	13
5	Erythrocytes identify complement activation in patients with COVID-19 2021 ·American Journal of Physiology-Lung Cellular and Molecular Physiology ·Lian Lam, John P. Reilly, Ann H. Rux, (unknown), Leticia Kuri-Cervantes, Ariel R. Weisman, C.A.G. Ittner, M. Betina Pampena, Michael R. Betts, E. John Wherry, Wen‐Chao Song, John D. Lambris, Nuala J. Meyer, Douglas B. Cines, Nilam S. Mangalmurti	43
6	C3 complement inhibition prevents antibody-mediated rejection and prolongs renal allograft survival in sensitized non-human primates 2021 ·Nature Communications ·Robin Schmitz, Zachary W. Fitch, Paul M. Schroder, Ashley Y. Choi, Miriam Manook, Janghoon Yoon, Mingqing Song, John S. Yi, Sanjay Khandelwal, Gowthami M. Arepally, Alton B. Farris, Edimara S. Reis, John D. Lambris, Jean Kwun, Stuart J. Knechtle	38
7	Complement mediates binding and procoagulant effects of ultralarge HIT immune complexes 2021 ·Blood ·Sanjay Khandelwal, (unknown), Lubica Rauova, Amrita Sarkar, Ann H. Rux, Serge Yarovoi, (unknown), John D. Lambris, (unknown), (unknown), Grace M. Lee, (unknown), Mortimer Poncz, Gowthami M. Arepally, Douglas B. Cines	24
8	Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood 2021 ·The Journal of Immunology ·(unknown), Dorte Christiansen, Hilde Fure, Judith Krey Ludviksen, Corinna Lau, John D. Lambris, Trent M. Woodruff, Ole‐Lars Brekke, Tonje Braaten, Erik Waage Nielsen, Tom Eirik Mollnes	10
9	CD14 inhibition improves survival and attenuates thrombo‐inflammation and cardiopulmonary dysfunction in a baboon model of Escherichia coli sepsis 2020 ·Journal of Thrombosis and Haemostasis ·Ravi S. Keshari, Robert Silasi‐Mansat, Narcis I. Popescu, (unknown), Hala Chaaban, John D. Lambris, Cristina Lupu, Tom Eirik Mollnes, Florea Lupu	18
10	Complement Activation via a C3a Receptor Pathway Alters CD4+ T Lymphocytes and Mediates Lung Cancer Progression 2017 ·Cancer Research ·Jeff Kwak, Jennifer Laskowski, Howard Li, Maria McSharry, Trisha R. Sippel, Bonnie Bullock, Amber M. Johnson, Joanna M. Poczobutt, Alexander Neuwelt, Stephen P. Malkoski, Mary C. Weiser-Evans, John D. Lambris, Eric T. Clambey, Joshua M. Thurman, Raphael A. Nemenoff	103
11	Complement-activation fragment C4a mediates effector functions by binding as untethered agonist to protease-activated receptors 1 and 4 2017 ·Proceedings of the National Academy of Sciences ·Hongbin Wang, Daniel Ricklin, John D. Lambris	84
12	High-Fat Diet-Induced Complement Activation Mediates Intestinal Inflammation and Neoplasia, Independent of Obesity 2016 ·Molecular Cancer Research ·(unknown), Edimara S. Reis, (unknown), (unknown), Jason D. Heaney, Nathan A. Berger, John D. Lambris, Joseph H. Nadeau	34
13	Regulators of complement activity mediate inhibitory mechanisms through a common C3b‐binding mode 2016 ·The EMBO Journal ·Federico Forneris, Jin Wu, (unknown), Daniel Ricklin, Zhuoer Lin, Georgia Sfyroera, Αποστολία Τζέκου, Elena B. Volokhina, J.C.M. Granneman, Richard E. Hauhart, Paula Bertram, M. Kathryn Liszewski, John P. Atkinson, John D. Lambris, Piet Gros	88
14	Systems Analysis of the Complement-Induced Priming Phase of Liver Regeneration 2016 ·The Journal of Immunology ·Jun Min, Robert A. DeAngelis, Edimara S. Reis, Shakti Gupta, Mano R. Maurya, Charles R. Evans, Arun K. Das, Charles Burant, John D. Lambris, Shankar Subramaniam	23
15	Compstatin: a C3‐targeted complement inhibitor reaching its prime for bedside intervention 2015 ·European Journal of Clinical Investigation ·Dimitrios C. Mastellos, Despina Yancopoulou, Petros Kokkinos, Markus Huber‐Lang, George Hajishengallis, (unknown), Florea Lupu, Bo Nilsson, Antonio M. Risitano, Daniel Ricklin, John D. Lambris	170
16	Immune responses to biosurfaces : mechanisms and therapeutic interventions 2015 ·Springer eBooks ·John D. Lambris	3
17	The Role of Complement in Retina Regeneration 2011 ·Investigative Ophthalmology & Visual Science ·Katia Del Rio‐Tsonis, Tracy Haynes, Αποστολία Τζέκου, (unknown), (unknown), Panagiotis A. Tsonis, John D. Lambris	1
18	The complement inhibitory protein DAF (CD55) suppresses T cell immunity in vivo 2005 ·The Journal of Experimental Medicine ·(unknown), Takashi Miwa, Brendan Hilliard, Youhai Chen, John D. Lambris, Andrew D. Wells, Wen-Chao Song	198
19	Protective Effects of IL-6 Blockade in Sepsis Are Linked to Reduced C5a Receptor Expression 2003 ·The Journal of Immunology ·Niels C. Riedemann, Thomas A. Neff, Ren-Feng Guo, Kurt D. Bernacki, Ines J. Laudes, J. Vidya Sarma, John D. Lambris, Peter A. Ward	256
20	Increased C5a receptor expression in sepsis 2002 ·Journal of Clinical Investigation ·Niels C. Riedemann, Renfeng Guo, Thomas A. Neff, Ines J. Laudes, (unknown), Vidya Sarma, Maciej M. Markiewski, Dimitrios C. Mastellos, Christoph W. Strey, Carl L. Pierson, John D. Lambris, Firas S. Zetoune, Peter A. Ward	18

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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