Jerry W. Shay

76.2k total citations · 19 hit papers
522 papers, 58.0k citations indexed

About

Jerry W. Shay is a scholar working on Molecular Biology, Physiology and Oncology. According to data from OpenAlex, Jerry W. Shay has authored 522 papers receiving a total of 58.0k indexed citations (citations by other indexed papers that have themselves been cited), including 291 papers in Molecular Biology, 278 papers in Physiology and 80 papers in Oncology. Recurrent topics in Jerry W. Shay's work include Telomeres, Telomerase, and Senescence (272 papers), DNA Repair Mechanisms (66 papers) and Cancer Research and Treatments (54 papers). Jerry W. Shay is often cited by papers focused on Telomeres, Telomerase, and Senescence (272 papers), DNA Repair Mechanisms (66 papers) and Cancer Research and Treatments (54 papers). Jerry W. Shay collaborates with scholars based in United States, Japan and Saudi Arabia. Jerry W. Shay's co-authors include Woodring E. Wright, Mieczyslaw A. Piatyszek, Silvia Bacchetti, Calvin B. Harley, Shawn E. Holt, Scott L. Weinrich, Michael D. West, Nam W. Kim, Karen R. Prowse and Gregg B. Morin and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Jerry W. Shay

518 papers receiving 56.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1994 6.0k citations Mieczyslaw A. Piatyszek, Calvin B. Harley et al. profile →
Extension of Life-Span by Introduction of Telomerase into Normal Human Cells

1998 3.9k citations Calvin B. Harley, Jerry W. Shay et al. profile →
A survey of telomerase activity in human cancer

1997 2.3k citations Jerry W. Shay et al. profile →
BRAFE600-associated senescence-like cell cycle arrest of human naevi

2005 1.6k citations Jerry W. Shay et al. profile →
Telomerase activity in human germline and embryonic tissues and cells

1996 1.1k citations Woodring E. Wright, Mieczyslaw A. Piatyszek et al. profile →
Activation of telomerase in human lymphocytes and hematopoietic progenitor cells

1995 757 citations Mieczyslaw A. Piatyszek, Jerry W. Shay et al. profile →
Human Telomerase and Its Regulation

2002 689 citations Woodring E. Wright, Jerry W. Shay et al. profile →
A transcriptionally active DNA-binding site for human p53 protein complexes.

1992 645 citations Woodring E. Wright, Jerry W. Shay et al. Molecular and Cellular Biology profile →
Absence of cancer–associated changes in human fibroblasts immortalized with telomerase

1999 641 citations Woodring E. Wright, Jerry W. Shay et al. profile →
Adult-onset pulmonary fibrosis caused by mutations in telomerase

2007 624 citations Kalliopi Tsakiri, Jennifer T. Cronkhite et al. Proceedings of the National Academy of Sciences profile →
Telomeres and telomerase: three decades of progress

2019 600 citations Jerry W. Shay, Woodring E. Wright profile →
Normal human chromosomes have long G-rich telomeric overhangs at one end

1997 586 citations Woodring E. Wright, Jerry W. Shay et al. profile →
A role for both RB and p53 in the regulation of human cellular senescence*1

1991 573 citations Jerry W. Shay profile →
Senescence and immortalization: role of telomeres and telomerase

2004 564 citations Jerry W. Shay, Woodring E. Wright profile →
Hayflick, his limit, and cellular ageing

2000 509 citations Jerry W. Shay, Woodring E. Wright profile →
Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies

2016 489 citations Jerry W. Shay et al. profile →
Role of Telomeres and Telomerase in Aging and Cancer

2016 470 citations Jerry W. Shay Cancer Discovery profile →
Telomerase, Cell Immortality, and Cancer

1994 342 citations Calvin B. Harley, Mieczyslaw A. Piatyszek et al. profile →
Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues.

1996 340 citations Mieczyslaw A. Piatyszek, Jerry W. Shay et al. profile →

Peers

Jerry W. Shay

PHYSI

ONCOL

BIOTE

GENET

Woodring E. Wright United States

Manuel Serrano Spain

Ronald A. DePinho United States

Calvin B. Harley United States

Alfred L. Goldberg United States

Carol W. Greider United States

Carlos López-Otı́n Spain

Randal J. Kaufman United States

Scott W. Lowe United States

Peter M. Lansdorp Canada

Woodring E. Wright United States

Jerry W. Shay

28.4k ×0.8

24.4k ×0.8

PHYSI

4.9k ×0.6

ONCOL

4.1k ×0.7

BIOTE

4.1k ×0.8

GENET

Citations per year, relative to Jerry W. Shay Jerry W. Shay (= 1×) peers Woodring E. Wright

Countries citing papers authored by Jerry W. Shay

Since Specialization

Citations

This map shows the geographic impact of Jerry W. Shay's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jerry W. Shay with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jerry W. Shay more than expected).

Fields of papers citing papers by Jerry W. Shay

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jerry W. Shay. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jerry W. Shay. The network helps show where Jerry W. Shay may publish in the future.

Co-authorship network of co-authors of Jerry W. Shay

This figure shows the co-authorship network connecting the top 25 collaborators of Jerry W. Shay. A scholar is included among the top collaborators of Jerry W. Shay based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jerry W. Shay. Jerry W. Shay is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Walser, Tonya C., Zhe Jing, Linh M. Tran, et al.. (2018). Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells. Cancer Research. 78(8). 1986–1999. 11 indexed citations

Zhang, Lu, Sang Bum Kim, Krishna Luitel, & Jerry W. Shay. (2018). Cholesterol Depletion by TASIN-1 Induces Apoptotic Cell Death through the ER Stress/ROS/JNK Signaling in Colon Cancer Cells. Molecular Cancer Therapeutics. 17(5). 943–951. 25 indexed citations

Pandita, Raj K., Tracy T. Chow, Durga Udayakumar, et al.. (2015). Single-Strand DNA-Binding Protein SSB1 Facilitates TERT Recruitment to Telomeres and Maintains Telomere G-Overhangs. Cancer Research. 75(5). 858–869. 14 indexed citations

Delgado, Oliver, Kimberly Batten, James A. Richardson, et al.. (2014). Radiation-Enhanced Lung Cancer Progression in a Transgenic Mouse Model of Lung Cancer Is Predictive of Outcomes in Human Lung and Breast Cancer. Clinical Cancer Research. 20(6). 1610–1622. 23 indexed citations

Mender, İlgen, Sergei Gryaznov, Z. Günnur Dikmen, Woodring E. Wright, & Jerry W. Shay. (2014). Induction of Telomere Dysfunction Mediated by the Telomerase Substrate Precursor 6-Thio-2′-Deoxyguanosine. Cancer Discovery. 5(1). 82–95. 114 indexed citations

Sullivan, James P., Luc Girard, Alexander Augustyn, et al.. (2014). Essential Role of Aldehyde Dehydrogenase 1A3 for the Maintenance of Non–Small Cell Lung Cancer Stem Cells Is Associated with the STAT3 Pathway. Clinical Cancer Research. 20(15). 4154–4166. 135 indexed citations

Sato, Mitsuo, Jill E. Larsen, Woochang Lee, et al.. (2013). Human Lung Epithelial Cells Progressed to Malignancy through Specific Oncogenic Manipulations. Molecular Cancer Research. 11(6). 638–650. 156 indexed citations

Singel, Stina Mui, Crystal Cornelius, Kimberly Batten, et al.. (2013). A Targeted RNAi Screen of the Breast Cancer Genome Identifies KIF14 and TLN1 as Genes That Modulate Docetaxel Chemosensitivity in Triple-Negative Breast Cancer. Clinical Cancer Research. 19(8). 2061–2070. 54 indexed citations

Fishbein, Michael C., Kostyantyn Krysan, John D. Minna, et al.. (2013). A Novel Molecular Pathway for Snail-Dependent, SPARC-Mediated Invasion in Non–Small Cell Lung Cancer Pathogenesis. Cancer Prevention Research. 7(1). 150–160. 31 indexed citations

10.

Eskiocak, Uğur, Sang Bum Kim, Peter Ly, et al.. (2011). Functional Parsing of Driver Mutations in the Colorectal Cancer Genome Reveals Numerous Suppressors of Anchorage-Independent Growth. Cancer Research. 71(13). 4359–4365. 22 indexed citations

11.

Sullivan, James P., Monica Spinola, Michael Dodge, et al.. (2010). Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling. Cancer Research. 70(23). 9937–9948. 334 indexed citations

12.

Marian, Calin O., Steve K. Cho, Brian McEllin, et al.. (2010). The Telomerase Antagonist, Imetelstat, Efficiently Targets Glioblastoma Tumor-Initiating Cells Leading to Decreased Proliferation and Tumor Growth. Clinical Cancer Research. 16(1). 154–163. 178 indexed citations

13.

Tressler, Robert, Ekaterina Bassett, Calvin B. Harley, et al.. (2010). The Telomerase Inhibitor Imetelstat Depletes Cancer Stem Cells in Breast and Pancreatic Cancer Cell Lines. Cancer Research. 70(22). 9494–9504. 107 indexed citations

14.

Shultz, Jacqueline C., Rachel W. Goehe, Dayanjan S. Wijesinghe, et al.. (2010). Alternative Splicing of Caspase 9 Is Modulated by the Phosphoinositide 3-Kinase/Akt Pathway via Phosphorylation of SRp30a. Cancer Research. 70(22). 9185–9196. 109 indexed citations

15.

Agarwal, Manjula, Shruti Pandita, Clayton R. Hunt, et al.. (2008). Inhibition of Telomerase Activity Enhances Hyperthermia-Mediated Radiosensitization. Cancer Research. 68(9). 3370–3378. 24 indexed citations

16.

Tsakiri, Kalliopi, Jennifer T. Cronkhite, Chao Xing, et al.. (2007). Adult-onset pulmonary fibrosis caused by mutations in telomerase. Proceedings of the National Academy of Sciences. 104(18). 7552–7557. 624 indexed citations breakdown →

17.

Das, Amit Kumar, Mitsuo Sato, Michael D. Story, et al.. (2006). Non–Small Cell Lung Cancers with Kinase Domain Mutations in the Epidermal Growth Factor Receptor Are Sensitive to Ionizing Radiation. Cancer Research. 66(19). 9601–9608. 178 indexed citations

18.

Nishi, Hirotaka, Toshihide Nakada, Satoru Kyo, et al.. (2004). Hypoxia-Inducible Factor 1 Mediates Upregulation of Telomerase (hTERT). Molecular and Cellular Biology. 24(13). 6076–6083. 164 indexed citations

19.

Troester, Melissa A., Katherine A. Hoadley, Thérese Sørlie, et al.. (2004). Cell-Type-Specific Responses to Chemotherapeutics in Breast Cancer. Cancer Research. 64(12). 4218–4226. 143 indexed citations

20.

Shay, Jerry W., Gail E. Tomlinson, Mieczyslaw A. Piatyszek, & Lauren Gollahon. (1995). Spontaneous In Vitro Immortalization of Breast Epithelial Cells from a Patient with Li-Fraumeni Syndrome. Molecular and Cellular Biology. 15(1). 425–432. 128 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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