Jerry W. Shay

76.2k citations

522 papers · 58.0k indexed · 19 hit papers · h-index 118

Molecular Biology top 0.02%
Physiology top 0.01%
Oncology top 0.1%
Biotechnology top 0.01%
Genetics top 0.1%

Co-authors: Woodring E. Wright Mieczyslaw A. Piatyszek Silvia Bacchetti Calvin B. Harley Shawn E. Holt Scott L. Weinrich Michael D. West Nam W. Kim
Topics: Telomeres, Telomerase, and Senescence (272 papers)DNA Repair Mechanisms (66 papers)Cancer Research and Treatments (54 papers)
Cited by: Aging Physiology Biotechnology
Journals: Nature Science Cell
Partner nations: United States Japan Saudi Arabia

In The Last Decade

Jerry W. Shay

518 papers receiving 56.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1994 6.0k citations Mieczyslaw A. Piatyszek, Calvin B. Harley et al. profile →
Extension of Life-Span by Introduction of Telomerase into Normal Human Cells

1998 3.9k citations Calvin B. Harley, Jerry W. Shay et al. profile →
A survey of telomerase activity in human cancer

1997 2.3k citations Jerry W. Shay et al. profile →
BRAFE600-associated senescence-like cell cycle arrest of human naevi

2005 1.6k citations Jerry W. Shay et al. profile →
Telomerase activity in human germline and embryonic tissues and cells

1996 1.1k citations Woodring E. Wright, Mieczyslaw A. Piatyszek et al. profile →
Activation of telomerase in human lymphocytes and hematopoietic progenitor cells

1995 757 citations Mieczyslaw A. Piatyszek, Jerry W. Shay et al. profile →
Human Telomerase and Its Regulation

2002 689 citations Woodring E. Wright, Jerry W. Shay et al. profile →
A transcriptionally active DNA-binding site for human p53 protein complexes.

1992 645 citations Woodring E. Wright, Jerry W. Shay et al. Molecular and Cellular Biology profile →
Absence of cancer–associated changes in human fibroblasts immortalized with telomerase

1999 641 citations Woodring E. Wright, Jerry W. Shay et al. profile →
Adult-onset pulmonary fibrosis caused by mutations in telomerase

2007 624 citations Kalliopi Tsakiri, Jennifer T. Cronkhite et al. Proceedings of the National Academy of Sciences profile →
Telomeres and telomerase: three decades of progress

2019 600 citations Jerry W. Shay, Woodring E. Wright profile →
Normal human chromosomes have long G-rich telomeric overhangs at one end

1997 586 citations Woodring E. Wright, Jerry W. Shay et al. profile →
A role for both RB and p53 in the regulation of human cellular senescence*1

1991 573 citations Jerry W. Shay profile →
Senescence and immortalization: role of telomeres and telomerase

2004 564 citations Jerry W. Shay, Woodring E. Wright profile →
Hayflick, his limit, and cellular ageing

2000 509 citations Jerry W. Shay, Woodring E. Wright profile →
Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies

2016 489 citations Jerry W. Shay et al. profile →
Role of Telomeres and Telomerase in Aging and Cancer

2016 470 citations Jerry W. Shay Cancer Discovery profile →
Telomerase, Cell Immortality, and Cancer

1994 342 citations Calvin B. Harley, Mieczyslaw A. Piatyszek et al. profile →
Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues.

1996 340 citations Mieczyslaw A. Piatyszek, Jerry W. Shay et al. profile →

Peers

Countries citing papers authored by Jerry W. Shay

Since Specialization

Citations

This map shows the geographic impact of Jerry W. Shay's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jerry W. Shay with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jerry W. Shay more than expected).

Fields of papers citing papers by Jerry W. Shay

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jerry W. Shay. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jerry W. Shay. The network helps show where Jerry W. Shay may publish in the future.

Co-authorship network of co-authors of Jerry W. Shay

This figure shows the co-authorship network connecting the top 25 collaborators of Jerry W. Shay. A scholar is included among the top collaborators of Jerry W. Shay based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jerry W. Shay. Jerry W. Shay is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells 2018 ·Cancer Research ·Tonya C. Walser,Zhe Jing,Linh M. Tran,Ying Q. Lin,(unknown),Gerald Wang,Kostyantyn Krysan,Li Zhu,Sherven Sharma,(unknown),John A. Belperio,Aik T. Ooi,Brigitte N. Gomperts,Jerry W. Shay,Jill E. Larsen,John D. Minna,(unknown),Michael C. Fishbein,Steven M. Dubinett	11
2	Cholesterol Depletion by TASIN-1 Induces Apoptotic Cell Death through the ER Stress/ROS/JNK Signaling in Colon Cancer Cells 2018 ·Molecular Cancer Therapeutics ·Lu Zhang,Sang Bum Kim,Krishna Luitel,Jerry W. Shay	25
3	Single-Strand DNA-Binding Protein SSB1 Facilitates TERT Recruitment to Telomeres and Maintains Telomere G-Overhangs 2015 ·Cancer Research ·Raj K. Pandita,Tracy T. Chow,Durga Udayakumar,Amanda L. Bain,Liza Cubeddu,Clayton R. Hunt,Wei Shi,Nobuo Horikoshi,Yong Zhao,Woodring E. Wright,Kum Kum Khanna,Jerry W. Shay,Tej K. Pandita	14
4	Radiation-Enhanced Lung Cancer Progression in a Transgenic Mouse Model of Lung Cancer Is Predictive of Outcomes in Human Lung and Breast Cancer 2014 ·Clinical Cancer Research ·Oliver Delgado,Kimberly Batten,James A. Richardson,(unknown),Adi F. Gazdar,(unknown),Luc Girard,Carmen Behrens,Milind Suraokar,(unknown),Woodring E. Wright,Michael D. Story,Ignacio I. Wistuba,John D. Minna,Jerry W. Shay	23
5	Induction of Telomere Dysfunction Mediated by the Telomerase Substrate Precursor 6-Thio-2′-Deoxyguanosine 2014 ·Cancer Discovery ·İlgen Mender,Sergei Gryaznov,Z. Günnur Dikmen,Woodring E. Wright,Jerry W. Shay	114
6	Essential Role of Aldehyde Dehydrogenase 1A3 for the Maintenance of Non–Small Cell Lung Cancer Stem Cells Is Associated with the STAT3 Pathway 2014 ·Clinical Cancer Research ·(unknown),James P. Sullivan,Luc Girard,Alexander Augustyn,Paul Yenerall,Jaime Rodriguez‐Canales,Hui Liu,Carmen Behrens,Jerry W. Shay,Ignacio I. Wistuba,John D. Minna	135
7	Human Lung Epithelial Cells Progressed to Malignancy through Specific Oncogenic Manipulations 2013 ·Molecular Cancer Research ·Mitsuo Sato,Jill E. Larsen,Woochang Lee,Han Sun,David S. Shames,Maithili P. Dalvi,Ruben D. Ramirez,Hao Tang,J. Michael DiMaio,Boning Gao,Yang Xie,Ignacio I. Wistuba,Adi F. Gazdar,Jerry W. Shay,John D. Minna	156
8	A Targeted RNAi Screen of the Breast Cancer Genome Identifies KIF14 and TLN1 as Genes That Modulate Docetaxel Chemosensitivity in Triple-Negative Breast Cancer 2013 ·Clinical Cancer Research ·Stina Mui Singel,Crystal Cornelius,Kimberly Batten,(unknown),Woodring E. Wright,Lawrence Lum,Jerry W. Shay	54
9	A Novel Molecular Pathway for Snail-Dependent, SPARC-Mediated Invasion in Non–Small Cell Lung Cancer Pathogenesis 2013 ·Cancer Prevention Research ·(unknown),Michael C. Fishbein,(unknown),Kostyantyn Krysan,John D. Minna,Jerry W. Shay,Tonya C. Walser,Steven M. Dubinett	31
10	Functional Parsing of Driver Mutations in the Colorectal Cancer Genome Reveals Numerous Suppressors of Anchorage-Independent Growth 2011 ·Cancer Research ·Uğur Eskiocak,Sang Bum Kim,Peter Ly,Andres I. Roig,(unknown),Kakajan Komurov,Crystal Cornelius,Woodring E. Wright,Michael A. White,Jerry W. Shay	22
11	Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling 2010 ·Cancer Research ·James P. Sullivan,Monica Spinola,Michael Dodge,Maria Gabriela Raso,Carmen Behrens,Boning Gao,Katja Schuster,Chunli Shao,Jill E. Larsen,Laura A. Sullivan,Sofia Honorio,Yang Xie,Pier Paolo Scaglioni,J. Michael DiMaio,Adi F. Gazdar,Jerry W. Shay,Ignacio I. Wistuba,John D. Minna	334
12	The Telomerase Antagonist, Imetelstat, Efficiently Targets Glioblastoma Tumor-Initiating Cells Leading to Decreased Proliferation and Tumor Growth 2010 ·Clinical Cancer Research ·Calin O. Marian,Steve K. Cho,Brian McEllin,Elizabeth A. Maher,Kimmo J. Hatanpaa,Christopher J. Madden,Bruce Mickey,Woodring E. Wright,Jerry W. Shay,Robert Bachoo	178
13	The Telomerase Inhibitor Imetelstat Depletes Cancer Stem Cells in Breast and Pancreatic Cancer Cell Lines 2010 ·Cancer Research ·(unknown),Robert Tressler,Ekaterina Bassett,Calvin B. Harley,Christen M. Buseman,(unknown),Woodring E. Wright,Jerry W. Shay,Ning Go	107
14	Alternative Splicing of Caspase 9 Is Modulated by the Phosphoinositide 3-Kinase/Akt Pathway via Phosphorylation of SRp30a 2010 ·Cancer Research ·Jacqueline C. Shultz,Rachel W. Goehe,Dayanjan S. Wijesinghe,(unknown),Amy J. Hawkins,Jerry W. Shay,John D. Minna,Charles E. Chalfant	109
15	Inhibition of Telomerase Activity Enhances Hyperthermia-Mediated Radiosensitization 2008 ·Cancer Research ·Manjula Agarwal,Shruti Pandita,Clayton R. Hunt,Arun Gupta,Yue Xuan,Saira Khan,Raj K. Pandita,David Pratt,Jerry W. Shay,John‐Stephen Taylor,Tej K. Pandita	24
16	Adult-onset pulmonary fibrosis caused by mutations in telomerasebreakdown → 2007 ·Proceedings of the National Academy of Sciences ·Kalliopi Tsakiri,Jennifer T. Cronkhite,(unknown),Chao Xing,Ganesh Raghu,Jonathan C. Weissler,Randall L. Rosenblatt,Jerry W. Shay,Christine Kim Garcia	624
17	Non–Small Cell Lung Cancers with Kinase Domain Mutations in the Epidermal Growth Factor Receptor Are Sensitive to Ionizing Radiation 2006 ·Cancer Research ·Amit Kumar Das,Mitsuo Sato,Michael D. Story,Michael Peyton,Robert J. Graves,Stella Redpath,Luc Girard,Adi F. Gazdar,Jerry W. Shay,John D. Minna,Chaitanya S. Nirodi	178
18	Hypoxia-Inducible Factor 1 Mediates Upregulation of Telomerase (hTERT) 2004 ·Molecular and Cellular Biology ·Hirotaka Nishi,Toshihide Nakada,Satoru Kyo,Masaki Inoue,Jerry W. Shay,Keiichi Isaka	164
19	Cell-Type-Specific Responses to Chemotherapeutics in Breast Cancer 2004 ·Cancer Research ·Melissa A. Troester,Katherine A. Hoadley,Thérese Sørlie,Brittney‐Shea Herbert,Anne‐Lise Børresen‐Dale,Per Eystein Lønning,Jerry W. Shay,William K. Kaufmann,Charles M. Perou	143
20	Spontaneous In Vitro Immortalization of Breast Epithelial Cells from a Patient with Li-Fraumeni Syndrome 1995 ·Molecular and Cellular Biology ·Jerry W. Shay,Gail E. Tomlinson,Mieczyslaw A. Piatyszek,Lauren Gollahon	128

About Jerry W. Shay

Jerry W. Shay is a scholar working on Aging, Physiology and Biotechnology, having authored 522 papers that have together received 58.0k indexed citations. Recurring topics across this work include Telomeres, Telomerase, and Senescence (272 papers), DNA Repair Mechanisms (66 papers) and Cancer Research and Treatments (54 papers). The work is most often cited by research in Aging (5.1k citations), Physiology (32.2k citations) and Biotechnology (6.0k citations). Jerry W. Shay has collaborated with scholars based in United States, Japan and Saudi Arabia. Frequent co-authors include Woodring E. Wright, Mieczyslaw A. Piatyszek, Silvia Bacchetti, Calvin B. Harley, Shawn E. Holt, Scott L. Weinrich, Michael D. West, Nam W. Kim, Karen R. Prowse and Gregg B. Morin. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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