Ignacio I. Wistuba

104.1k total citations · 10 hit papers
687 papers, 36.0k citations indexed

About

Ignacio I. Wistuba is a scholar working on Oncology, Pulmonary and Respiratory Medicine and Molecular Biology. According to data from OpenAlex, Ignacio I. Wistuba has authored 687 papers receiving a total of 36.0k indexed citations (citations by other indexed papers that have themselves been cited), including 321 papers in Oncology, 294 papers in Pulmonary and Respiratory Medicine and 277 papers in Molecular Biology. Recurrent topics in Ignacio I. Wistuba's work include Lung Cancer Treatments and Mutations (201 papers), Cancer Genomics and Diagnostics (144 papers) and Cancer Immunotherapy and Biomarkers (87 papers). Ignacio I. Wistuba is often cited by papers focused on Lung Cancer Treatments and Mutations (201 papers), Cancer Genomics and Diagnostics (144 papers) and Cancer Immunotherapy and Biomarkers (87 papers). Ignacio I. Wistuba collaborates with scholars based in United States, Netherlands and Chile. Ignacio I. Wistuba's co-authors include Adi F. Gazdar, Carmen Behrens, John D. Minna, J. Jack Lee, Jaime Rodriguez‐Canales, Ximing Tang, Junya Fujimoto, Jack A. Roth, César A. Moran and John V. Heymach and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Ignacio I. Wistuba

663 papers receiving 35.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

PD-L1 as a biomarker of response to immune-checkpoint inhibitors

2021 980 citations Ignacio I. Wistuba et al. profile →
Epidemiology and Molecular Pathology of Gallbladder Cancer

2001 635 citations Ignacio I. Wistuba et al. profile →
Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer

2019 616 citations Junya Fujimoto, Jing Wang et al. Cancer Discovery profile →
A Prospective, Multi-institutional, Pathologist-Based Assessment of 4 Immunohistochemistry Assays for PD-L1 Expression in Non–Small Cell Lung Cancer

2017 576 citations Junya Fujimoto, Ignacio I. Wistuba et al. profile →
NRF2 regulates serine biosynthesis in non–small cell lung cancer

2015 560 citations Hao Tang, Yang Xie et al. profile →
Somatic Mutations of the HER2 Kinase Domain in Lung Adenocarcinomas

2005 517 citations Ignacio I. Wistuba, John D. Minna et al. Cancer Research profile →
KRASMutation Is an Important Predictor of Resistance to Therapy with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer

2007 500 citations Marileila Varella‐Garcia, Ximing Tang et al. Clinical Cancer Research profile →
VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer

2017 455 citations Ignacio I. Wistuba, Jorge Blando et al. profile →
Epithelial–Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma

2016 349 citations Edwin R. Parra, Jing Wang et al. Clinical Cancer Research profile →
Cancer biomarkers: Emerging trends and clinical implications for personalized treatment

2024 235 citations Ignacio I. Wistuba et al. profile →

Peers

Countries citing papers authored by Ignacio I. Wistuba

Since Specialization

Citations

This map shows the geographic impact of Ignacio I. Wistuba's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ignacio I. Wistuba with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ignacio I. Wistuba more than expected).

Fields of papers citing papers by Ignacio I. Wistuba

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ignacio I. Wistuba. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ignacio I. Wistuba. The network helps show where Ignacio I. Wistuba may publish in the future.

Co-authorship network of co-authors of Ignacio I. Wistuba

This figure shows the co-authorship network connecting the top 25 collaborators of Ignacio I. Wistuba. A scholar is included among the top collaborators of Ignacio I. Wistuba based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ignacio I. Wistuba. Ignacio I. Wistuba is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Image Analysis–based Assessment of PD-L1 and Tumor-Associated Immune Cells Density Supports Distinct Intratumoral Microenvironment Groups in Non–small Cell Lung Carcinoma Patients 2016 ·Clinical Cancer Research ·Edwin R. Parra, Carmen Behrens, Jaime Rodriguez‐Canales, Heather Lin, Barbara Mino, Jorge Blando, Jianjun Zhang, Don L. Gibbons, John V. Heymach, Boris Sepesi, Stephen G. Swisher, Annikka Weissferdt, Neda Kalhor, Julie Izzo, Humam Kadara, César A. Moran, J. Jack Lee, Ignacio I. Wistuba	103
2	Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5 2015 ·Molecular Cancer Research ·Hui Tian, Jui-Yun Lu, (unknown), Kenneth E. Huffman, (unknown), Jill E. Larsen, Luc Girard, Hui Liu, Jaime Rodriguez‐Canales, Eugene P. Frenkel, Ignacio I. Wistuba, John D. Minna, Sandra L. Hofmann	37
3	ETS2 Mediated Tumor Suppressive Function and MET Oncogene Inhibition in Human Non–Small Cell Lung Cancer 2013 ·Clinical Cancer Research ·Mohamed Kabbout, Melinda Garcia, Junya Fujimoto, Diane D. Liu, Denise M. Woods, Chi‐Wan Chow, Gabriela Mendoza, Amin A. Momin, Brian P. James, Luisa M. Solis, Carmen Behrens, J. Jack Lee, Ignacio I. Wistuba, Humam Kadara	116
4	RHOA-FAK Is a Required Signaling Axis for the Maintenance of KRAS-Driven Lung Adenocarcinomas 2013 ·Cancer Discovery ·Georgia Konstantinidou, Giorgio Ramadori, Francesca Torti, Kim Kangasniemi, (unknown), Yiran Cai, Carmen Behrens, Michael T. Dellinger, Rolf A. Brekken, Ignacio I. Wistuba, Adriana Heguy, Julie Teruya‐Feldstein, Pier Paolo Scaglioni	91
5	Prediction of Survival in Resected Non–Small Cell Lung Cancer Using a Protein Expression–Based Risk Model: Implications for Personalized Chemoprevention and Therapy 2013 ·Clinical Cancer Research ·Kathryn A. Gold, Edward S. Kim, Diane D. Liu, Ping Yuan, Carmen Behrens, Luisa M. Solis, Humam Kadara, David C. Rice, Ignacio I. Wistuba, Stephen G. Swisher, Wayne L. Hofstetter, J. Jack Lee, Waun Ki Hong	27
6	Identification of a Subset of Human Non–Small Cell Lung Cancer Patients with High PI3Kβ and Low PTEN Expression, More Prevalent in Squamous Cell Carcinoma 2013 ·Clinical Cancer Research ·Marie Cumberbatch, Ximing Tang, Garry Beran, (unknown), Xin Wang, Rebecca Ellston, Simon Dearden, Sabina Cosulich, Paul D. Smith, Carmen Behrens, Edward S. Kim, Xinying Su, Shuqiong Fan, Neil Gray, David P. Blowers, Ignacio I. Wistuba, Chris Womack	22
7	Human Lung Epithelial Cells Progressed to Malignancy through Specific Oncogenic Manipulations 2013 ·Molecular Cancer Research ·Mitsuo Sato, Jill E. Larsen, Woochang Lee, Han Sun, David S. Shames, Maithili P. Dalvi, Ruben D. Ramirez, Hao Tang, J. Michael DiMaio, Boning Gao, Yang Xie, Ignacio I. Wistuba, Adi F. Gazdar, Jerry W. Shay, John D. Minna	156
8	Characterizing the Molecular Spatial and Temporal Field of Injury in Early-Stage Smoker Non–Small Cell Lung Cancer Patients after Definitive Surgery by Expression Profiling 2012 ·Cancer Prevention Research ·Humam Kadara, Li Shen, Junya Fujimoto, Pierre Saintigny, Chi‐Wan Chow, Wenhua Lang, (unknown), Melinda Garcia, Mohamed Kabbout, You-Hong Fan, Carmen Behrens, (unknown), Li Mao, J. Jack Lee, Kathryn A. Gold, Jing Wang, Kevin R. Coombes, Edward S. Kim, Waun Ki Hong, Ignacio I. Wistuba	26
9	Abnormalities of the TITF-1 Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis 2011 ·Clinical Cancer Research ·Ximing Tang, Humam Kadara, Carmen Behrens, Diane D. Liu, Yun Xiao, David C. Rice, Adi F. Gazdar, Junya Fujimoto, César A. Moran, Marileila Varella‐Garcia, J. Jack Lee, Waun Ki Hong, Ignacio I. Wistuba	59
10	Differential Impacts of Insulin-Like Growth Factor-Binding Protein-3 (IGFBP-3) in Epithelial IGF-Induced Lung Cancer Development 2011 ·Endocrinology ·Woo‐Young Kim, Mi-Jung Kim, Hojin Moon, Ping Yuan, Jin‐Soo Kim, Jong Kyu Woo, Guangcheng Zhang, Young‐Ah Suh, Lei Feng, Carmen Behrens, Carolyn S. Van Pelt, Hyunseok Kang, J. Jack Lee, (unknown), Ignacio I. Wistuba, Ho‐Young Lee	19
11	Robust Gene Expression Signature from Formalin-Fixed Paraffin-Embedded Samples Predicts Prognosis of Non–Small-Cell Lung Cancer Patients 2011 ·Clinical Cancer Research ·Yang Xie, Guanghua Xiao, Kevin R. Coombes, Carmen Behrens, Luisa M. Solis, Gabriela Raso, Luc Girard, Heidi S. Erickson, Jack A. Roth, John V. Heymach, César A. Moran, K. D. Danenberg, John D. Minna, Ignacio I. Wistuba	130
12	Biological Activity of Celecoxib in the Bronchial Epithelium of Current and Former Smokers 2010 ·Cancer Prevention Research ·Edward S. Kim, Waun Ki Hong, J. Jack Lee, Li Mao, Rodolfo C. Morice, Diane D. Liu, Carlos A. Jiménez, Georgie A. Eapen, Reuben Lotan, Ximing Tang, Robert A. Newman, Ignacio I. Wistuba, Jonathan M. Kurie	39
13	Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling 2010 ·Cancer Research ·James P. Sullivan, Monica Spinola, Michael Dodge, Maria Gabriela Raso, Carmen Behrens, Boning Gao, Katja Schuster, Chunli Shao, Jill E. Larsen, Laura A. Sullivan, Sofia Honorio, Yang Xie, Pier Paolo Scaglioni, J. Michael DiMaio, Adi F. Gazdar, Jerry W. Shay, Ignacio I. Wistuba, John D. Minna	334
14	A Five-Gene and Corresponding Protein Signature for Stage-I Lung Adenocarcinoma Prognosis 2010 ·Clinical Cancer Research ·Humam Kadara, Carmen Behrens, Ping Yuan, Luisa M. Solis, Diane Liu, Xuemin Gu, John D. Minna, J. Jack Lee, Edward Kim, (unknown), Ignacio I. Wistuba, Reuben Lotan	68
15	Collagen XXIII: A Potential Biomarker for the Detection of Primary and Recurrent Non–Small Cell Lung Cancer 2010 ·Cancer Epidemiology Biomarkers & Prevention ·(unknown), Jacqueline Banyard, Luisa M. Solis, Ignacio I. Wistuba, Justine A. Barletta, Leena Gandhi, Henry A. Feldman, Scott J. Rodig, Lucian R. Chirieac, Bruce R. Zetter	29
16	Elevated Epithelial Insulin-like Growth Factor Expression Is a Risk Factor for Lung Cancer Development 2009 ·Cancer Research ·Woo-Young Kim, Quanri Jin, (unknown), Edward S. Kim, (unknown), Dong Hoon Lee, Lei Feng, Carmen Behrens, Ludmila Prudkin, York E. Miller, J. Jack Lee, Scott M. Lippman, Waun Ki Hong, Ignacio I. Wistuba, Ho‐Young Lee	60
17	Phase II Randomized, Placebo-Controlled Trial of Green Tea Extract in Patients with High-Risk Oral Premalignant Lesions 2009 ·Cancer Prevention Research ·Anne S. Tsao, Diane Liu, Jack W. Martin, (unknown), J. Jack Lee, Adel K. El‐Naggar, Ignacio I. Wistuba, Kirk S. Culotta, Li Mao, Ann M. Gillenwater, Yuko M. Sagesaka, Waun Ki Hong, Vassiliki A. Papadimitrakopoulou	182
18	Identification of Gene Signatures and Molecular Markers for Human Lung Cancer Prognosis using an In vitro Lung Carcinogenesis System 2009 ·Cancer Prevention Research ·Humam Kadara, Ludovic Lacroix, Carmen Behrens, Luisa M. Solis, Xuemin Gu, J. Jack Lee, E Tahara, Dafna Lotan, Waun Ki Hong, Ignacio I. Wistuba, Reuben Lotan	49
19	Loss and Reduction of Fus1 Protein Expression is a Frequent Phenomenon in the Pathogenesis of Lung Cancer 2008 ·Clinical Cancer Research ·Ludmila Prudkin, Carmen Behrens, Diane D. Liu, (unknown), Natalie Ozburn, B. Nebiyou Bekele, John D. Minna, César A. Moran, Jack A. Roth, Lin Ji, Ignacio I. Wistuba	68
20	High Expression of Ligands for Chemokine Receptor CXCR2 in Alveolar Epithelial Neoplasia Induced by Oncogenic Kras 2006 ·Cancer Research ·Marie Wislez, Nobukazu Fujimoto, Julie Izzo, Amy E. Hanna, Dianna D. Cody, Robert R. Langley, Hongli Tang, Marie D. Burdick, Mitsuo Sato, John D. Minna, Li Mao, Ignacio I. Wistuba, Robert M. Strieter, Jonathan M. Kurie	130

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