Calvin B. Harley

42.2k total citations · 14 hit papers
112 papers, 33.5k citations indexed

About

Calvin B. Harley is a scholar working on Physiology, Molecular Biology and Immunology. According to data from OpenAlex, Calvin B. Harley has authored 112 papers receiving a total of 33.5k indexed citations (citations by other indexed papers that have themselves been cited), including 77 papers in Physiology, 57 papers in Molecular Biology and 18 papers in Immunology. Recurrent topics in Calvin B. Harley's work include Telomeres, Telomerase, and Senescence (71 papers), Genetics, Aging, and Longevity in Model Organisms (17 papers) and RNA Interference and Gene Delivery (15 papers). Calvin B. Harley is often cited by papers focused on Telomeres, Telomerase, and Senescence (71 papers), Genetics, Aging, and Longevity in Model Organisms (17 papers) and RNA Interference and Gene Delivery (15 papers). Calvin B. Harley collaborates with scholars based in United States, Canada and United Kingdom. Calvin B. Harley's co-authors include Carol W. Greider, A. B. Futcher, Woodring E. Wright, Jerry W. Shay, Scott L. Weinrich, Richard Allsopp, Michael D. West, Gregg B. Morin, Nam W. Kim and Mieczyslaw A. Piatyszek and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Calvin B. Harley

109 papers receiving 32.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1994 6.0k citations Nam W. Kim, Mieczyslaw A. Piatyszek et al. Science profile →
Telomeres shorten during ageing of human fibroblasts

1990 4.5k citations Calvin B. Harley, A. B. Futcher et al. Nature profile →
Extension of Life-Span by Introduction of Telomerase into Normal Human Cells

1998 3.9k citations Choy‐Pik Chiu, Calvin B. Harley et al. Science profile →
Telomerase Catalytic Subunit Homologs from Fission Yeast and Human

1997 1.9k citations Scott L. Weinrich, William H. Andrews et al. Science profile →
The RNA Component of Human Telomerase

1995 1.9k citations Walter D. Funk, Scott L. Weinrich et al. Science profile →
Telomere length predicts replicative capacity of human fibroblasts.

1992 1.8k citations Richard Allsopp, A. B. Futcher et al. profile →
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

1992 1.8k citations Carol W. Greider, Calvin B. Harley et al. profile →
Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

1994 915 citations Richard Allsopp, Calvin B. Harley et al. profile →
Analysis of E.Coli Pormoter sequences

1987 905 citations Calvin B. Harley et al. profile →
Telomere end-replication problem and cell aging

1992 834 citations Michael Z. Levy, Richard Allsopp et al. Journal of Molecular Biology profile →
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

1997 812 citations Scott L. Weinrich, Nam W. Kim et al. profile →
Telomerase and cancer therapeutics

2008 571 citations Calvin B. Harley profile →
Telomere length and replicative aging in human vascular tissues.

1995 515 citations Calvin B. Harley et al. profile →
Telomerase, Cell Immortality, and Cancer

1994 342 citations Calvin B. Harley, Karen R. Prowse et al. profile →

Peers

Countries citing papers authored by Calvin B. Harley

Since Specialization

Citations

This map shows the geographic impact of Calvin B. Harley's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Calvin B. Harley with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Calvin B. Harley more than expected).

Fields of papers citing papers by Calvin B. Harley

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Calvin B. Harley. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Calvin B. Harley. The network helps show where Calvin B. Harley may publish in the future.

Co-authorship network of co-authors of Calvin B. Harley

This figure shows the co-authorship network connecting the top 25 collaborators of Calvin B. Harley. A scholar is included among the top collaborators of Calvin B. Harley based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Calvin B. Harley. Calvin B. Harley is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	A Novel Telomerase Activator Suppresses Lung Damage in a Murine Model of Idiopathic Pulmonary Fibrosis 2013 ·PLoS ONE ·Claude Jourdan Le Saux, Philip Davy, Christopher Brampton, Seema S. Ahuja, (unknown), Pooja Shivshankar, (unknown), Mahesh Ramaseshan, Robert Tressler, (unknown), Calvin B. Harley, Richard Allsopp	60
2	Neural Tumor-Initiating Cells Have Distinct Telomere Maintenance and Can be Safely Targeted for Telomerase Inhibition 2011 ·Clinical Cancer Research ·Pedro Castelo‐Branco, Cindy Zhang, Tatiana Lipman, (unknown), Loen M. Hansford, Ian D. Clarke, Calvin B. Harley, Robert Tressler, David Malkin, Erin J. Walker, David R. Kaplan, Peter B. Dirks, Uri Tabori	35
3	Astragaloside IV and Cycloastragenol Stimulate the Phosphorylation of Extracellular Signal-Regulated Protein Kinase in Multiple Cell Types 2011 ·Planta Medica ·Lisa Y. Yung, Wing Lam, Maurice K.C. Ho, Yue‐Qing Hu, Fanny C.F. Ip, (unknown), Allison C. Chin, Calvin B. Harley, Nancy Y. Ip, Yung Hou Wong	38
4	The Telomerase Inhibitor Imetelstat Depletes Cancer Stem Cells in Breast and Pancreatic Cancer Cell Lines 2010 ·Cancer Research ·(unknown), Robert Tressler, Ekaterina Bassett, Calvin B. Harley, Christen M. Buseman, (unknown), Woodring E. Wright, Jerry W. Shay, Ning Go	107
5	A Natural Product Telomerase Activator As Part of a Health Maintenance Program 2010 ·Rejuvenation Research ·Calvin B. Harley, Wei‐Min Liu, Marı́a A. Blasco, Elsa Vera, William H. Andrews, Laura Briggs, (unknown)	138
6	Telomerase-Based Pharmacologic Enhancement of Antiviral Function of Human CD8+ T Lymphocytes 2008 ·The Journal of Immunology ·(unknown), Beth D. Jamieson, Allison C. Chin, Ronald T. Mitsuyasu, (unknown), Hwee L. Ng, Christina M. Ramirez, Otto O. Yang, Calvin B. Harley, Rita B. Effros	135
7	Human Ageing and Telomeres 2007 ·Novartis Foundation symposium ·Calvin B. Harley	30
8	The novel telomerase inhibitor GRN163L targets drug-resistant cancer stem cells in multiple myeloma 2007 ·Molecular Cancer Therapeutics ·William Matsui, Qiuju Wang, Sarah Brennan, Alan K. Meeker, Robert Tressler, Calvin B. Harley, Carol Ann Huff, B. Douglas Smith, Richard Jones	1
9	Telomerase Therapeutics for Degenerative Diseases 2005 ·Current Molecular Medicine ·Calvin B. Harley	39
10	Lipid modification of GRN163, an N3′ → P5′ thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition 2005 ·Oncogene ·Brittney‐Shea Herbert, Ginelle C. Gellert, Amelia E. Hochreiter, Krisztina Pongracz, Woodring E. Wright, Daria Zielińska, Allison C. Chin, Calvin B. Harley, Jerry W. Shay, Sergei Gryaznov	184
11	Telomerase Antagonists GRN163 and GRN163L Inhibit Tumor Growth and Increase Chemosensitivity of Human Hepatoma * 2005 ·Hepatology ·Meta W. Djojosubroto, Allison C. Chin, Ning Go, Sonja Schaetzlein, Michael P. Manns, Sergei Gryaznov, Calvin B. Harley, K. Lenhard Rudolph	111
12	Telomere length assessment in tissue sections by quantitative FISH: Image analysis algorithms 2004 ·Cytometry Part A ·Jacintha O’Sullivan, Jennifer C. Finley, (unknown), (unknown), Katherine A. Gollahon, Alexander H. Moskovitz, Sergei Gryaznov, Calvin B. Harley, Peter S. Rabinovitch	71
13	Telomerase Expression Restores Dermal Integrity to in Vitro-Aged Fibroblasts in a Reconstituted Skin Model 2000 ·Experimental Cell Research ·Walter D. Funk, (unknown), Dawne N. Shelton, Calvin B. Harley, (unknown), Warren K. Hoeffler	115
14	Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis 1996 ·AIDS ·Rita B. Effros, Richard Allsopp, Choy‐Pik Chiu, Mary Ann Hausner, Karim F. Hirji, Lili Wang, Calvin B. Harley, Bryant Villeponteau, Michael D. West, Janis V. Giorgi	371
15	9 Telomeres and Aging 1995 ·Cold Spring Harbor Monograph Archive ·Calvin B. Harley	66
16	Specific Association of Human Telomerase Activity with Immortal Cells and Cancer breakdown → 1994 ·Science ·Nam W. Kim, Mieczyslaw A. Piatyszek, Karen R. Prowse, Calvin B. Harley, Michael D. West, (unknown), (unknown), Woodring E. Wright, Scott L. Weinrich, Jerry W. Shay	5978
17	Wild-Type Coat Protein Gene of Tobacco Mosaic Virus Mutant Ni 2519 1993 ·Journal of General Virology ·David Zimmern, (unknown), Calvin B. Harley	3
18	Telomere end-replication problem and cell aging breakdown → 1992 ·Journal of Molecular Biology ·Michael Z. Levy, Richard Allsopp, A. B. Futcher, Carol W. Greider, Calvin B. Harley	834
19	Fetal bovine serum contains an inhibitor of interleukin-1 1990 ·Journal of Immunological Methods ·Roderick C. McKenzie, Calvin B. Harley, (unknown), Daniel N. Sauder	10
20	Molecular cloning and expression of the major protein kinase C substrate of platelets 1988 ·Nature ·Michael Tyers, Richard A. Rachubinski, (unknown), Angela Varrichio, Robert Shorr, Richard J. Haslam, Calvin B. Harley	210

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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