Shawn E. Holt

11.6k total citations · 3 hit papers
63 papers, 9.4k citations indexed

About

Shawn E. Holt is a scholar working on Physiology, Molecular Biology and Genetics. According to data from OpenAlex, Shawn E. Holt has authored 63 papers receiving a total of 9.4k indexed citations (citations by other indexed papers that have themselves been cited), including 45 papers in Physiology, 30 papers in Molecular Biology and 10 papers in Genetics. Recurrent topics in Shawn E. Holt's work include Telomeres, Telomerase, and Senescence (44 papers), Cancer Research and Treatments (10 papers) and Mesenchymal stem cell research (10 papers). Shawn E. Holt is often cited by papers focused on Telomeres, Telomerase, and Senescence (44 papers), Cancer Research and Treatments (10 papers) and Mesenchymal stem cell research (10 papers). Shawn E. Holt collaborates with scholars based in United States, Canada and Poland. Shawn E. Holt's co-authors include Woodring E. Wright, Jerry W. Shay, Gregg B. Morin, Michel Ouellette, Serge Lichtsteiner, Andrea Bodnár, Calvin B. Harley, Choy‐Pik Chiu, Lynne W. Elmore and David A. Gewirtz and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Shawn E. Holt

63 papers receiving 9.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Extension of Life-Span by Introduction of Telomerase into Normal Human Cells

1998 3.9k citations Andrea Bodnár, Michel Ouellette et al. profile →
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

1997 812 citations Scott L. Weinrich, R. Pruzan et al. Nature Genetics profile →
Absence of cancer–associated changes in human fibroblasts immortalized with telomerase

1999 641 citations Shawn E. Holt, Michel M. Ouellette et al. Nature Genetics profile →

Peers

Countries citing papers authored by Shawn E. Holt

Since Specialization

Citations

This map shows the geographic impact of Shawn E. Holt's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shawn E. Holt with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shawn E. Holt more than expected).

Fields of papers citing papers by Shawn E. Holt

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shawn E. Holt. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shawn E. Holt. The network helps show where Shawn E. Holt may publish in the future.

Co-authorship network of co-authors of Shawn E. Holt

This figure shows the co-authorship network connecting the top 25 collaborators of Shawn E. Holt. A scholar is included among the top collaborators of Shawn E. Holt based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Shawn E. Holt. Shawn E. Holt is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Defining essential stem cell characteristics in adipose-derived stromal cells extracted from distinct anatomical sites 2012 ·Cell and Tissue Research ·Patrick C. Sachs, Michael P. Francis, Min Zhao, Jenni Brumelle, Raj R. Rao, Lynne W. Elmore, Shawn E. Holt	57
2	Electrospinning adipose tissue‐derived extracellular matrix for adipose stem cell culture 2012 ·Journal of Biomedical Materials Research Part A ·Michael P. Francis, Patrick C. Sachs, Parthasarathy Madurantakam, Scott A. Sell, Lynne W. Elmore, Gary L. Bowlin, Shawn E. Holt	42
3	Multipotent adipose stromal cells and breast cancer development: Think globally, act locally 2010 ·Molecular Carcinogenesis ·Min Zhao, (unknown), Shawn E. Holt, Matthew J. Beckman, Lynne W. Elmore	50
4	Elevated TRF2 in advanced breast cancers with short telomeres 2010 ·Breast Cancer Research and Treatment ·Malissa Diehl, Michael O. Idowu, (unknown), Timothy P. York, Colleen Jackson‐Cook, (unknown), Shawn E. Holt, Lynne W. Elmore	33
5	Elevated expression of nuclear Hsp90 in invasive breast tumors 2009 ·Cancer Biology & Therapy ·Malissa Diehl, Michael O. Idowu, (unknown), Timothy P. York, Lynne W. Elmore, Shawn E. Holt	28
6	Initiation of a Zebrafish Blastula Cell Line on Rainbow Trout Stromal Cells and Subsequent Development Under Feeder-Free Conditions into a Cell Line, ZEB2J 2008 ·Zebrafish ·(unknown), Lucy E. J. Lee, Lianchun Fan, Paul Collodi, Shawn E. Holt, Niels C. Bols	31
7	Recovery from stress is a function of age and telomere length 2008 ·Cell Stress and Chaperones ·Graham M. Strub, (unknown), Lynne W. Elmore, Shawn E. Holt	6
8	Ectopic telomerase expression inhibits neuronal differentiation of NT2 neural progenitor cells 2007 ·Neuroscience Letters ·R. Mark Richardson, Binh Nguyen, Shawn E. Holt, William C. Broaddus, Helen L. Fillmore	18
9	A Cell Line (HEW) from Embryos of Haddock (Melanogrammus aeglefinius) and Its Capacity to Tolerate Environmental Extremes 2006 ·Marine Biotechnology ·(unknown), Elizabeth Joyce, (unknown), Lucy E. J. Lee, Shawn E. Holt, (unknown), Kazuhiro Fujiki, Brian Dixon, Niels C. Bols	33
10	Vertebrate Marine Species as Model Systems for Studying Telomeres and Telomerase 2005 ·Zebrafish ·Patricia A. McChesney, Lynne W. Elmore, Shawn E. Holt	22
11	erbB-2/neu Transformed Rat Cholangiocytes Recapitulate Key Cellular and Molecular Features of Human Bile Duct Cancer 2005 ·Gastroenterology ·Guan‐Hua Lai, Zichen Zhang, Xue‐Ning Shen, (unknown), (unknown), Shawn E. Holt, (unknown), Douglas C. Hixson, Alphonse E. Sirica	55
12	Telomere Maintenance: At the Crossroads of Mismatch Repair 2004 ·Cancer Biology & Therapy ·Binh Nguyen, Lynne W. Elmore, Shawn E. Holt	2
13	Telomerase Resets the Homeostatic Telomere Length and Prevents Telomere Dysfunction in Immortalized Human Cells 2004 ·DNA and Cell Biology ·Patricia A. McChesney, (unknown), Colleen Jackson‐Cook, Lynne W. Elmore, Shawn E. Holt	1
14	Human chromosomes with shorter telomeres and large heterochromatin regions have a higher frequency of acquired somatic cell aneuploidy 2004 ·Mechanisms of Ageing and Development ·Natalia T. Leach, Catherine Rehder, (unknown), Shawn E. Holt, Colleen Jackson‐Cook	43
15	Adriamycin-induced Senescence in Breast Tumor Cells Involves Functional p53 and Telomere Dysfunction 2002 ·Journal of Biological Chemistry ·Lynne W. Elmore, Catherine Rehder, Xu Di, Patricia A. McChesney, Colleen Jackson‐Cook, David A. Gewirtz, Shawn E. Holt	207
16	Stable Association of hsp90 and p23, but Not hsp70, with Active Human Telomerase 2001 ·Journal of Biological Chemistry ·(unknown), (unknown), John W. Turner, Lynne W. Elmore, Shawn E. Holt	183
17	Subsenescent Telomere Lengths in Fibroblasts Immortalized by Limiting Amounts of Telomerase 2000 ·Journal of Biological Chemistry ·Michel M. Ouellette, (unknown), Brittney‐Shea Herbert, (unknown), Shawn E. Holt, (unknown), Jerry W. Shay, Woodring E. Wright	223
18	Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT breakdown → 1997 ·Nature Genetics ·Scott L. Weinrich, R. Pruzan, Libin Ma, Michel Ouellette, (unknown), Shawn E. Holt, Andrea Bodnár, Serge Lichtsteiner, Nam W. Kim, James Trager, Rebecca D. Taylor, (unknown), William H. Andrews, Woodring E. Wright, Jerry W. Shay, Calvin B. Harley, Gregg B. Morin	812
19	Refining the telomere-telomerase hypothesis of aging and cancer 1996 ·Nature Biotechnology ·Shawn E. Holt, Jerry W. Shay, Woodring E. Wright	139
20	An accessory protein enhances both DNA binding and activity of DNA polymerase α isolated from normal, but not transformed, human fibroblasts 1996 ·Mutation Research/DNAging ·(unknown), Susan M. Miller, Vinod K. Srivastava, (unknown), Shawn E. Holt, Van G. Wilson, David L. Busbee	6

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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