Ian R. Mackenzie

52.4k citations

209 papers · 19.5k indexed · 4 hit papers · h-index 67

Neurology top 0.01%
Molecular Biology top 0.5%
Physiology top 0.1%
Genetics top 0.05%
Neurology top 0.05%

Co-authors: Manuela Neumann Rosa Rademakers Howard Feldman Hans A. Kretzschmar John Q. Trojanowski Linda K. Kwong David G. Muñoz Bruce L. Miller
Topics: Amyotrophic Lateral Sclerosis Research (113 papers)Alzheimer's disease research and treatments (78 papers)Parkinson's Disease Mechanisms and Treatments (56 papers)
Cited by: Neurology Genetics
Journals: Science Proceedings of the National Academy of Sciences Journal of Biological Chemistry
Partner nations: Canada United States Germany

In The Last Decade

Ian R. Mackenzie

200 papers receiving 19.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

2006 4.8k citations Manuela Neumann, Deepak M. Sampathu et al. Science profile →
Pathological TDP‐43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations

2007 761 citations Ian R. Mackenzie, Eileen H. Bigio et al. Annals of Neurology profile →
TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia

2010 718 citations Ian R. Mackenzie, Rosa Rademakers et al. profile →
ALS‐associated fused in sarcoma (FUS) mutations disrupt Transportin‐mediated nuclear import

2010 644 citations Ian R. Mackenzie, Manuela Neumann et al. profile →

Peers

Countries citing papers authored by Ian R. Mackenzie

Since Specialization

Citations

This map shows the geographic impact of Ian R. Mackenzie's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ian R. Mackenzie with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ian R. Mackenzie more than expected).

Fields of papers citing papers by Ian R. Mackenzie

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ian R. Mackenzie. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ian R. Mackenzie. The network helps show where Ian R. Mackenzie may publish in the future.

Co-authorship network of co-authors of Ian R. Mackenzie

This figure shows the co-authorship network connecting the top 25 collaborators of Ian R. Mackenzie. A scholar is included among the top collaborators of Ian R. Mackenzie based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ian R. Mackenzie. Ian R. Mackenzie is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Relationship between efficacy and preferential targeting of soluble Aβ aggregates 2025 ·Alzheimer s & Dementia Translational Research & Clinical Interventions ·Johanne Kaplan,Ebrima Gibbs,(unknown),Beibei Zhao,Ian R. Mackenzie,Steven S. Plotkin,Neil R. Cashman	0
2	Clinical decision points for two plasma p‐tau217 laboratory developed tests in neuropathology confirmed samples 2025 ·Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring ·(unknown),Ging‐Yuek Robin Hsiung,(unknown),K.G. Hallett,Ian R. Mackenzie,Veronica Hirsch‐Reinshagen,(unknown),(unknown),Mary Joy Encarnacion,(unknown)	2
3	Decoding amyloid beta clearance systems at inner blood–retina barrier using three‐dimensional ex vivo retinal imaging in Alzheimer's disease 2025 ·Alzheimer s & Dementia ·(unknown),Alireza Hosseini,Matthew Campbell,(unknown),(unknown),(unknown),Ian R. Mackenzie,Veronica Hirsch‐Reinshagen,Ging‐Yuek Robin Hsiung,Benjamin W. Spiller,Brian E. Wadzinski,Wellington Pham,Joanne A. Matsubara	0
4	Local structural preferences in shaping tau amyloid polymorphism 2024 ·Nature Communications ·Nikolaos Louros,Martin Wilkinson,(unknown),Meine Ramakers,(unknown),Teresa García,Rodrigo Gallardo,(unknown),Vera Goossens,Dominique Audenaert,Dietmar Rudolf Thal,Ian R. Mackenzie,Rosa Rademakers,Neil A. Ranson,Sheena E. Radford,Frédéric Rousseau,Joost Schymkowitz	16
5	Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase 2024 ·Nature Communications ·Hideyuki Takahashi,(unknown),(unknown),Hongping Ye,Xianlin Han,Marius Chiasseu,Guilin Wang,Ian R. Mackenzie,Stephen M. Strittmatter	13
6	Limbic-predominant age-related TDP-43 proteinopathy (LATE-NC) is associated with abundant TMEM106B pathology 2023 ·Acta Neuropathologica ·Manuela Neumann,Jolien Perneel,Simon Cheung,Marleen Van den Broeck,Haakon B. Nygaard,Ging‐Yuek Robin Hsiung,(unknown),Bavo Heeman,Rosa Rademakers,Ian R. Mackenzie	10
7	C-terminal TMEM106B fragments in human brain correlate with disease-associated TMEM106B haplotypes 2023 ·Brain ·Cristina T. Vicente,Jolien Perneel,(unknown),(unknown),Marleen Van den Broeck,Matt Baker,Simon Cheung,Júlia Faura,Ian R. Mackenzie,Rosa Rademakers	16
8	The spectrum of disease and tau pathology of nodding syndrome in Uganda 2022 ·Brain ·Michael S. Pollanen,(unknown),Paul M. McKeever,Janice Robertson,Ian R. Mackenzie,Gábor G. Kovács,(unknown),David Lagoro Kitara,(unknown)	13
9	Predicting thermal comfort for diverse populations 2021 ·Building Simulation Conference proceedings ·Nathaniel Jones,(unknown),Ian R. Mackenzie,(unknown),(unknown)	1
10	Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway 2021 ·Nature Neuroscience ·Yen‐Chen Lin,(unknown),Nandini Ramesh,Eric N. Anderson,Aivi T. Nguyen,(unknown),Simon Cheung,Justin A. McDonough,William C. Skarnes,(unknown),John E. Landers,Nicolas L. Fawzi,Ian R. Mackenzie,Edward B. Lee,Jeffrey A. Nickerson,David Grünwald,Udai Bhan Pandey,Daryl A. Bosco	63
11	Expanding the Phenotype of Frontotemporal Lobar Degeneration With FUS-Positive Pathology (FTLD-FUS) 2020 ·Journal of Neuropathology & Experimental Neurology ·(unknown),Veronica Hirsch‐Reinshagen,Mari Perez‐Rosendahl,Howard Feldman,Freddi Segal‐Gidan,Harry V. Vinters,Ian R. Mackenzie	6
12	Clinicopathologic correlations in a family with aTBK1mutation presenting as primary progressive aphasia and primary lateral sclerosis 2019 ·Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration ·Veronica Hirsch‐Reinshagen,(unknown),Ging‐Yuek Robin Hsiung,Cyril Pottier,Matt Baker,Ralph B. Perkerson,Rosa Rademakers,(unknown),Dean Foti,Ian R. Mackenzie	23
13	Rabies Encephalitis:AIRP Best Cases in Radiologic-Pathologic Correlation 2015 ·Radiographics ·(unknown),Ian R. Mackenzie,Jason R. Shewchuk	7
14	Targeted manipulation of the sortilin–progranulin axis rescues progranulin haploinsufficiency 2013 ·Human Molecular Genetics ·Chris W. Lee,Sandra Almeida,Mercedes Prudencio,Thomas R. Caulfield,Yong‐Jie Zhang,William M. Tay,Peter Bauer,Jeannie Chew,Hiroki Sasaguri,Karen Jansen‐West,Tania F. Gendron,Caroline Stetler,NiCole A. Finch,Ian R. Mackenzie,Rosa Rademakers,Fen‐Biao Gao,Leonard Petrucelli	78
15	Progranulin Deficiency Decreases Gross Neural Connectivity But Enhances Transmission at Individual Synapses 2011 ·Journal of Neuroscience ·Lucı́a Tapia,Austen J. Milnerwood,(unknown),Fergil Mills,(unknown),Cristina Vasuta,Ian R. Mackenzie,Lynn A. Raymond,Max S. Cynader,William Jia,Shernaz X. Bamji	73
16	The spectrum and severity of FUS-immunoreactive inclusions in the frontal and temporal lobes of ten cases of neuronal intermediate filament inclusion disease 2010 ·Acta Neuropathologica ·Richard A. Armstrong,Marla Gearing,Eileen H. Bigio,Felix Cruz-Sánchez,Charles Duyckaerts,Ian R. Mackenzie,Robert H. Perry,Kari Skullerud,(unknown),Nigel J. Cairns	19
17	FUS pathology in basophilic inclusion body disease 2009 ·Acta Neuropathologica ·David G. Muñoz,Manuela Neumann,Hirofumi Kusaka,Osamu Yokota,Kenji Ishihara,Seishi Terada,Shigetoshi Kuroda,Ian R. Mackenzie	189
18	Pathological TDP‐43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutationsbreakdown → 2007 ·Annals of Neurology ·Ian R. Mackenzie,Eileen H. Bigio,Paul G. Ince,Felix Geser,Manuela Neumann,Nigel J. Cairns,Linda K. Kwong,Mark S. Forman,John Ravits,Heather Stewart,Andrew Eisen,(unknown),Hans A. Kretzschmar,Camelia Maria Monoranu,J. Robin Highley,Janine Kirby,Teepu Siddique,Pamela J. Shaw,(unknown),John Q. Trojanowski	761
19	Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosisbreakdown → 2006 ·Science ·Manuela Neumann,Deepak M. Sampathu,Linda K. Kwong,(unknown),Matthew C. Micsenyi,Thomas T. Chou,Jennifer Bruce,Theresa Schuck,Murray Grossman,Christopher M. Clark,Leo McCluskey,Bruce L. Miller,Eliezer Masliah,Ian R. Mackenzie,Howard Feldman,W. Feiden,Hans A. Kretzschmar,John Q. Trojanowski,Virginia M.‐Y. Lee	4830
20	Die frontotemporale Demenz 2003 ·Der Nervenarzt ·Janine Diehl,Ian R. Mackenzie,Hans Förstl,Alexander Kurz	0

About Ian R. Mackenzie

Ian R. Mackenzie is a scholar working on Neurology, Neurology and Physiology, having authored 209 papers that have together received 19.5k indexed citations. Recurring topics across this work include Amyotrophic Lateral Sclerosis Research (113 papers), Alzheimer's disease research and treatments (78 papers) and Parkinson's Disease Mechanisms and Treatments (56 papers). The work is most often cited by research in Neurology (13.6k citations), Genetics (5.4k citations) and Neurology (4.1k citations). Ian R. Mackenzie has collaborated with scholars based in Canada, United States and Germany. Frequent co-authors include Manuela Neumann, Rosa Rademakers, Howard Feldman, Hans A. Kretzschmar, John Q. Trojanowski, Linda K. Kwong, David G. Muñoz, Bruce L. Miller, Virginia M.‐Y. Lee and Deepak M. Sampathu. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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