Karl H. Jakobs

11.8k total citations · 2 hit papers
175 papers, 10.0k citations indexed

About

Karl H. Jakobs is a scholar working on Molecular Biology, Cell Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Karl H. Jakobs has authored 175 papers receiving a total of 10.0k indexed citations (citations by other indexed papers that have themselves been cited), including 150 papers in Molecular Biology, 37 papers in Cell Biology and 24 papers in Cellular and Molecular Neuroscience. Recurrent topics in Karl H. Jakobs's work include Receptor Mechanisms and Signaling (73 papers), Protein Kinase Regulation and GTPase Signaling (61 papers) and Cellular transport and secretion (31 papers). Karl H. Jakobs is often cited by papers focused on Receptor Mechanisms and Signaling (73 papers), Protein Kinase Regulation and GTPase Signaling (61 papers) and Cellular transport and secretion (31 papers). Karl H. Jakobs collaborates with scholars based in Germany, United States and Netherlands. Karl H. Jakobs's co-authors include Klaus Aktories, Dagmar Meyer zu Heringdorf, Martina Schmidt, Günter Schultz, Thomas Wieland, Peter Gierschik, Silvia Bauer, Chris J. van Koppen, Yasuhiro Watanabe and Paschal A. Oude Weernink and has published in prestigious journals such as Nature, Journal of Biological Chemistry and Nature Genetics.

In The Last Decade

Karl H. Jakobs

174 papers receiving 9.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Protein kinase C phosphorylates the inhibitory guanine‐nucleotide‐binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase

1985 641 citations Karl H. Jakobs et al. European Journal of Biochemistry profile →
Association of a human G-protein β3 subunit variant with hypertension

1998 612 citations Winfried Siffert, Dieter Rosskopf et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Karl H. Jakobs Germany	58	7.7k	2.1k	2.0k	1.3k	865	175	10.0k
Peter Gierschik Germany	57	6.9k 0.9×	1.6k 0.8×	1.6k 0.8×	923 0.7×	881 1.0×	173	9.7k
Eva J. Neer United States	47	10.1k 1.3×	3.1k 1.5×	2.3k 1.1×	825 0.6×	1.2k 1.4×	102	12.2k
Elliott M. Ross United States	54	9.6k 1.3×	3.5k 1.7×	2.0k 1.0×	1.0k 0.8×	362 0.4×	114	11.6k
Juan Codina United States	57	9.8k 1.3×	4.6k 2.2×	1.4k 0.7×	1.2k 0.9×	1.4k 1.6×	143	11.8k
M Ui Japan	53	9.2k 1.2×	2.5k 1.2×	2.2k 1.1×	1.5k 1.1×	647 0.7×	99	12.1k
Paul C. Sternweis United States	63	12.7k 1.7×	3.4k 1.6×	3.5k 1.8×	1.3k 1.0×	510 0.6×	103	15.2k
Yehia Daaka United States	45	7.6k 1.0×	3.1k 1.5×	1.2k 0.6×	1.1k 0.8×	725 0.8×	97	10.0k
Shirish Shenolikar United States	57	9.6k 1.3×	3.1k 1.5×	2.6k 1.3×	920 0.7×	604 0.7×	172	13.0k
Dermot M.F. Cooper United States	61	7.8k 1.0×	3.6k 1.7×	987 0.5×	1.5k 1.2×	952 1.1×	163	10.7k
Donal A. Walsh United States	47	7.1k 0.9×	995 0.5×	1.6k 0.8×	1.1k 0.8×	480 0.6×	131	9.5k

Countries citing papers authored by Karl H. Jakobs

Since Specialization

Citations

This map shows the geographic impact of Karl H. Jakobs's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Karl H. Jakobs with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Karl H. Jakobs more than expected).

Fields of papers citing papers by Karl H. Jakobs

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Karl H. Jakobs. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Karl H. Jakobs. The network helps show where Karl H. Jakobs may publish in the future.

Co-authorship network of co-authors of Karl H. Jakobs

This figure shows the co-authorship network connecting the top 25 collaborators of Karl H. Jakobs. A scholar is included among the top collaborators of Karl H. Jakobs based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Karl H. Jakobs. Karl H. Jakobs is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Rosskopf, Dieter, et al.. (2003). Interaction of Gβ3s, a splice variant of the G-protein Gβ3, with Gγ- and Gα-proteins. Cellular Signalling. 15(5). 479–488. 36 indexed citations

Heringdorf, Dagmar Meyer zu, Károly Liliom, Michael Schaefer, et al.. (2003). Photolysis of intracellular caged sphingosine‐1‐phosphate causes Ca²⁺ mobilization independently of G‐protein‐coupled receptors. FEBS Letters. 554(3). 443–449. 84 indexed citations

Hippe, Hans‐Joerg, Susanne Lutz, Friederike Cuello, et al.. (2003). Activation of Heterotrimeric G Proteins by a High Energy Phosphate Transfer via Nucleoside Diphosphate Kinase (NDPK) B and Gβ Subunits. Journal of Biological Chemistry. 278(9). 7227–7233. 80 indexed citations

Heringdorf, Dagmar Meyer zu, et al.. (2003). Sphingosylphosphorylcholine, a naturally occurring lipid mediator, inhibits human platelet function. British Journal of Pharmacology. 138(3). 435–444. 12 indexed citations

Schmidt, Martina, Sandrine Evellin, Paschal A. Oude Weernink, et al.. (2001). A new phospholipase-C–calcium signalling pathway mediated by cyclic AMP and a Rap GTPase. Nature Cell Biology. 3(11). 1020–1024. 287 indexed citations

Alemany, Regina, et al.. (2000). Stimulation of Sphingosine-1-phosphate Formation by the P2Y₂Receptor in HL-60 Cells: Ca²⁺Requirement and Implication in Receptor-Mediated Ca²⁺Mobilization, but Not MAP Kinase Activation. Molecular Pharmacology. 58(3). 491–497. 33 indexed citations

Rümenapp, Ulrich, et al.. (1999). Rho‐specific binding and guanine nucleotide exchange catalysis by KIAA0380, a Dbl family member. FEBS Letters. 459(3). 313–318. 49 indexed citations

Schmidt, Martina, et al.. (1996). Chapter 20 Participation of small GTP-binding proteins in m3 muscarinic acetylcholine receptor signalling to phospholipase D and C. Progress in brain research. 109. 209–216. 4 indexed citations

Schmidt, Martina, et al.. (1995). Rapid and Persistent Desensitization of m3 Muscarinic Acetylcholine Receptor-stimulated Phospholipase D. Journal of Biological Chemistry. 270(34). 19949–19956. 39 indexed citations

10.

Wieland, Thomas & Karl H. Jakobs. (1994). [1] Measurement of receptor-stimulated guanosine 5′-O-(γ-thio)triphosphate binding by G proteins. Methods in enzymology on CD-ROM/Methods in enzymology. 237. 3–13. 125 indexed citations

11.

Wieland, Thomas, et al.. (1993). Receptor-stimulated dissociation of GTP[S] from Gi-proteins in membranes of HL-60 cells. Cellular Signalling. 5(4). 425–433. 11 indexed citations

12.

Ligeti, Erzsébet, Véronique Pizon, Alfred Wittinghofer, Peter Gierschik, & Karl H. Jakobs. (1993). GTPase activity of small GTP‐binding proteins in HL‐60 membranes is stimulated by arachidonic acid. European Journal of Biochemistry. 216(3). 813–820. 15 indexed citations

13.

Liebmann, Claus, et al.. (1991). High-affinity bradykinin receptor-catalyzed G protein activation in rat myometrium. European Journal of Pharmacology Molecular Pharmacology. 207(1). 67–71. 11 indexed citations

14.

Wieland, Thomas, Isabel Ulibarri, Peter Gierschik, & Karl H. Jakobs. (1991). Activation of signal‐transducing guanine‐nucleotide‐binding regulatory proteins by guanosine 5′‐[γ‐thio]triphosphate. European Journal of Biochemistry. 196(3). 707–716. 44 indexed citations

15.

Reithmann, Christopher, Peter Gierschik, Karl Werdan, & Karl H. Jakobs. (1991). Tumor necrosis factor α up-regulates Giα and Gß proteins and adenylyl cyclase responsiveness in rat cardiomyocytes. European Journal of Pharmacology Molecular Pharmacology. 206(1). 53–60. 42 indexed citations

16.

Wieland, Thomas & Karl H. Jakobs. (1989). Receptor‐regulated formation of GTP[γS] with subsequent persistent G_s‐protein activation in membranes of human platelets. FEBS Letters. 245(1-2). 189–193. 33 indexed citations

17.

Gierschik, Peter, et al.. (1989). Muscarinic acetylcholine receptor‐stimulated binding of guanosine 5′‐O‐(3‐thiotriphosphate) to guanine‐nucleotide‐binding proteins in cardiac membranes. European Journal of Biochemistry. 186(3). 725–731. 165 indexed citations

18.

Böhm, Michael, Peter Gierschik, Karl H. Jakobs, et al.. (1989). Localization of a “postreceptor” defect in human dilated cardiomyopathy. The American Journal of Cardiology. 64(12). 812–814. 32 indexed citations

19.

Aktories, Klaus, Günter Schultz, & Karl H. Jakobs. (1982). Adenosine receptor-mediated stimulation of GTP hydrolysis in adipocyte membranes. Life Sciences. 30(3). 269–275. 20 indexed citations

20.

Jakobs, Karl H., et al.. (1978). Metal and Metal-ATP Interactions with Human Platelet Adenylate Cyclase: Effects of Alpha Adrenergic Inhibition. Molecular Pharmacology. 14(6). 1073–1078. 17 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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