Arjan Kortholt

3.5k total citations · 1 hit paper
74 papers, 2.5k citations indexed

About

Arjan Kortholt is a scholar working on Molecular Biology, Cell Biology and Neurology. According to data from OpenAlex, Arjan Kortholt has authored 74 papers receiving a total of 2.5k indexed citations (citations by other indexed papers that have themselves been cited), including 48 papers in Molecular Biology, 37 papers in Cell Biology and 25 papers in Neurology. Recurrent topics in Arjan Kortholt's work include Cellular Mechanics and Interactions (27 papers), Parkinson's Disease Mechanisms and Treatments (25 papers) and Cell Adhesion Molecules Research (14 papers). Arjan Kortholt is often cited by papers focused on Cellular Mechanics and Interactions (27 papers), Parkinson's Disease Mechanisms and Treatments (25 papers) and Cell Adhesion Molecules Research (14 papers). Arjan Kortholt collaborates with scholars based in Netherlands, Germany and United States. Arjan Kortholt's co-authors include Peter J.M. Van Haastert, Ineke Keizer‐Gunnink, Alfred Wittinghofer, Bernd K. Gilsbach, Henderikus Pots, Wim Versées, Lina Wauters, Susanne Terheyden, Asmaa Oun and Amalia M. Dolga and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Communications.

In The Last Decade

Arjan Kortholt

73 papers receiving 2.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A homologue of the Parkinson’s disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover

2017 402 citations Egon Deyaert, Lina Wauters et al. Nature Communications profile →

Peers

Countries citing papers authored by Arjan Kortholt

Since Specialization

Citations

This map shows the geographic impact of Arjan Kortholt's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Arjan Kortholt with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Arjan Kortholt more than expected).

Fields of papers citing papers by Arjan Kortholt

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Arjan Kortholt. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Arjan Kortholt. The network helps show where Arjan Kortholt may publish in the future.

Co-authorship network of co-authors of Arjan Kortholt

This figure shows the co-authorship network connecting the top 25 collaborators of Arjan Kortholt. A scholar is included among the top collaborators of Arjan Kortholt based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Arjan Kortholt. Arjan Kortholt is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Characterization of Lipopolysaccharide Effects on LRRK2 Signaling in RAW Macrophages 2023 ·International Journal of Molecular Sciences ·Asmaa Oun, (unknown), (unknown), (unknown), (unknown), Henderikus Pots, Marina Trombetta-Lima, Arjan Kortholt, Amalia M. Dolga	5
2	LRRK2 Structure-Based Activation Mechanism and Pathogenesis 2023 ·Biomolecules ·Xiaojuan Zhang, Arjan Kortholt	12
3	The beneficial effect of salubrinal on neuroinflammation and neuronal loss in intranigral LPS-induced hemi-Parkinson disease model in rats 2022 ·Immunopharmacology and Immunotoxicology ·(unknown), (unknown), Caner Günaydın, (unknown), S. Sırrı Bilge, Özlem Özmen, (unknown), Arjan Kortholt	13
4	Nanobodies as allosteric modulators of Parkinson’s disease–associated LRRK2 2022 ·Proceedings of the National Academy of Sciences ·Ranjan K. Singh, (unknown), Giambattista Guaitoli, (unknown), Felix von Zweydorf, Thomas Dal Maso, Asmaa Oun, (unknown), Sven H. Schmidt, Deep Chatterjee, (unknown), Els Pardon, Thomas Schwartz, Stefan Knapp, Eileen J. Kennedy, Jan Steyaert, Friedrich W. Herberg, Arjan Kortholt, Christian Johannes Gloeckner, Wim Versées	31
5	The Roc domain of LRRK2 as a hub for protein-protein interactions: a focus on PAK6 and its impact on RAB phosphorylation 2022 ·Brain Research ·Susanna Cogo, (unknown), Elena Tosoni, James E. Tomkins, Isabella Tessari, Lucia Iannotta, Thomas J. Montine, Claudia Manzoni, Patrick A. Lewis, Luigi Bubacco, Marie‐Christine Chartier‐Harlin, Jean‐Marc Taymans, Arjan Kortholt, (unknown), Laura Cendron, Laura Civiero, Elisa Greggio	7
6	LRRK2 protects immune cells against erastin-induced ferroptosis 2022 ·Neurobiology of Disease ·Asmaa Oun, (unknown), Marina Trombetta-Lima, (unknown), (unknown), Arjan Kortholt, Amalia M. Dolga	14
7	Allosteric Inhibition of Parkinson’s-Linked LRRK2 by Constrained Peptides 2021 ·ACS Chemical Biology ·(unknown), (unknown), Felix von Zweydorf, (unknown), (unknown), (unknown), Bernd K. Gilsbach, (unknown), Panagiotis S. Athanasopoulos, Ranjan K. Singh, (unknown), Wim Versées, Francesco Raimondi, Friedrich W. Herberg, Christian Johannes Gloeckner, Hardy J. Rideout, Arjan Kortholt, Eileen J. Kennedy	20
8	Forty-five years of cGMP research in Dictyostelium: understanding the regulation and function of the cGMP pathway for cell movement and chemotaxis 2021 ·Molecular Biology of the Cell ·Peter J.M. Van Haastert, Ineke Keizer‐Gunnink, Henderikus Pots, (unknown), Douwe M. Veltman, (unknown), Arjan Kortholt	6
9	Membrane Targeting of C2GAP1 Enables Dictyostelium discoideum to Sense Chemoattractant Gradient at a Higher Concentration Range 2021 ·Frontiers in Cell and Developmental Biology ·Xuehua Xu, (unknown), Henderikus Pots, Xi Wen, Taeck J. Jeon, Arjan Kortholt, Tian Jin	5
10	The neuroprotective action of lenalidomide on rotenone model of Parkinson's Disease: Neurotrophic and supportive actions in the substantia nigra pars compacta 2020 ·Neuroscience Letters ·(unknown), Caner Günaydın, S. Sırrı Bilge, Özlem Özmen, Arjan Kortholt	8
11	Allosteric modulation of the GTPase activity of a bacterial LRRK2 homolog by conformation-specific Nanobodies 2020 ·Biochemical Journal ·Margaux Leemans, (unknown), Egon Deyaert, Elise Daems, Linda Krause, (unknown), Els Pardon, Jan Steyaert, Arjan Kortholt, Frank Sobott, Dagmar Klostermeier, Wim Versées	11
12	A homologue of the Parkinson’s disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover breakdown → 2017 ·Nature Communications ·Egon Deyaert, Lina Wauters, Giambattista Guaitoli, Albert Konijnenberg, Margaux Leemans, Susanne Terheyden, Arsen Petrović, Rodrigo Gallardo, Laura M. Nederveen-Schippers, Panagiotis S. Athanasopoulos, Henderikus Pots, Peter J.M. Van Haastert, Frank Sobott, Christian Johannes Gloeckner, Rouslan G. Efremov, Arjan Kortholt, Wim Versées	402
13	The LRR-Roc-COR module of theChlorobium tepidumRoco protein: crystallization and X-ray crystallographic analysis 2017 ·Acta Crystallographica Section F Structural Biology Communications ·Egon Deyaert, Arjan Kortholt, Wim Versées	4
14	Activation Mechanism of LRRK2 and Its Cellular Functions in Parkinson’s Disease 2016 ·Parkinson s Disease ·(unknown), Arjan Kortholt	29
15	Homer3 regulates the establishment of neutrophil polarity 2015 ·Molecular Biology of the Cell ·Julie Wu, (unknown), (unknown), Fabrizia Fusetti, Wynand Alkema, Shanshan Liu, Steven J. Altschuler, Lani F. Wu, Arjan Kortholt, Orion D. Weiner	22
16	Structural biology of the LRRK2 GTPase and kinase domains: implications for regulation 2014 ·Frontiers in Molecular Neuroscience ·Bernd K. Gilsbach, Arjan Kortholt	60
17	Structure of the Roc–COR domain tandem of C. tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinase 2008 ·The EMBO Journal ·Katja Gotthardt, Michael Weyand, Arjan Kortholt, Peter J.M. Van Haastert, Alfred Wittinghofer	122
18	Highlighting the role of Ras and Rap during Dictyostelium chemotaxis 2008 ·Cellular Signalling ·Arjan Kortholt, Peter J.M. Van Haastert	64
19	Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis 2007 ·The Journal of Cell Biology ·Peter J.M. Van Haastert, Ineke Keizer‐Gunnink, Arjan Kortholt	95
20	Characterization of the GbpD-activated Rap1 Pathway Regulating Adhesion and Cell Polarity in Dictyostelium discoideum 2006 ·Journal of Biological Chemistry ·Arjan Kortholt, Holger Rehmann, (unknown), Leonard Bosgraaf, Ineke Keizer‐Gunnink, Gerald Weeks, Alfred Wittinghofer, Peter J.M. Van Haastert	48

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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