Robbert H. Cool

7.1k total citations · 2 hit papers
84 papers, 5.7k citations indexed

About

Robbert H. Cool is a scholar working on Molecular Biology, Immunology and Genetics. According to data from OpenAlex, Robbert H. Cool has authored 84 papers receiving a total of 5.7k indexed citations (citations by other indexed papers that have themselves been cited), including 62 papers in Molecular Biology, 18 papers in Immunology and 17 papers in Genetics. Recurrent topics in Robbert H. Cool's work include Protein Kinase Regulation and GTPase Signaling (19 papers), Bacterial Genetics and Biotechnology (16 papers) and Cell death mechanisms and regulation (13 papers). Robbert H. Cool is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (19 papers), Bacterial Genetics and Biotechnology (16 papers) and Cell death mechanisms and regulation (13 papers). Robbert H. Cool collaborates with scholars based in Netherlands, Germany and France. Robbert H. Cool's co-authors include Alfred Wittinghofer, Johannes L. Bos, Johan de Rooij, Wim J. Quax, Fried Zwartkruis, Sebastian Nijman, Mark H. G. Verheijen, Gudrun Koch, Pol Nadal‐Jimenez and Karina B. Xavier and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Robbert H. Cool

84 papers receiving 5.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

1998 1.6k citations Johan de Rooij, Robbert H. Cool et al. profile →
The Multiple Signaling Systems Regulating Virulence in Pseudomonas aeruginosa

2012 551 citations Pol Nadal‐Jimenez, Gudrun Koch et al. Microbiology and Molecular Biology Reviews profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Robbert H. Cool Netherlands	37	4.5k	693	673	654	521	84	5.7k
Shuji Takahashi Japan	37	3.2k 0.7×	464 0.7×	438 0.7×	538 0.8×	304 0.6×	212	5.4k
Noelle S. Williams United States	45	4.3k 1.0×	479 0.7×	348 0.5×	994 1.5×	284 0.5×	113	6.9k
Marjan Guček United States	45	4.5k 1.0×	241 0.3×	839 1.2×	577 0.9×	437 0.8×	117	6.8k
Robert Schwarzenbacher United States	33	4.8k 1.1×	579 0.8×	641 1.0×	989 1.5×	759 1.5×	51	6.7k
Swadesh K. Das United States	44	3.2k 0.7×	629 0.9×	667 1.0×	858 1.3×	575 1.1×	153	6.3k
Nicholas J. G. Webster United States	42	3.7k 0.8×	1.7k 2.4×	311 0.5×	700 1.1×	532 1.0×	116	6.7k
Axel H. Schönthal United States	54	4.6k 1.0×	679 1.0×	1.7k 2.5×	701 1.1×	399 0.8×	170	8.1k
Xingming Deng United States	52	5.5k 1.2×	253 0.4×	873 1.3×	641 1.0×	274 0.5×	103	7.4k
Erwin Knecht Spain	40	3.1k 0.7×	713 1.0×	1.7k 2.5×	323 0.5×	195 0.4×	104	5.8k
Takeshi Nagasu Japan	30	3.7k 0.8×	288 0.4×	442 0.7×	253 0.4×	302 0.6×	60	5.7k

Countries citing papers authored by Robbert H. Cool

Since Specialization

Citations

This map shows the geographic impact of Robbert H. Cool's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robbert H. Cool with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robbert H. Cool more than expected).

Fields of papers citing papers by Robbert H. Cool

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robbert H. Cool. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robbert H. Cool. The network helps show where Robbert H. Cool may publish in the future.

Co-authorship network of co-authors of Robbert H. Cool

This figure shows the co-authorship network connecting the top 25 collaborators of Robbert H. Cool. A scholar is included among the top collaborators of Robbert H. Cool based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robbert H. Cool. Robbert H. Cool is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

1.

Chen, Deng, Maxim Gureev, Zhangping Xiao, et al.. (2023). Allosteric Inhibitors of Macrophage Migration Inhibitory Factor (MIF) Interfere with Apoptosis-Inducing Factor (AIF) Co-Localization to Prevent Parthanatos. Journal of Medicinal Chemistry. 66(13). 8767–8781. 6 indexed citations

2.

Xiao, Zhangping, Shanshan Song, Deng Chen, et al.. (2021). Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti‐Proliferative Activity in Lung Cancer Cells. Angewandte Chemie. 133(32). 17655–17662. 3 indexed citations

3.

Xiao, Zhangping, Shanshan Song, Deng Chen, et al.. (2021). Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti‐Proliferative Activity in Lung Cancer Cells. Angewandte Chemie International Edition. 60(32). 17514–17521. 37 indexed citations

4.

Cool, Robbert H., et al.. (2018). Small-molecule inhibitors of macrophage migration inhibitory factor (MIF) as an emerging class of therapeutics for immune disorders. Drug Discovery Today. 23(11). 1910–1918. 48 indexed citations

5.

Sloot, Almer M. van der, Carlos R. Reis, Shane Deegan, et al.. (2015). Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity. Oncogene. 35(10). 1261–1270. 51 indexed citations

6.

Koch, Gudrun, Pol Nadal‐Jimenez, Robbert H. Cool, & Wim J. Quax. (2014). Assessing Pseudomonas Virulence with Nonmammalian Host: Galleria mellonella. Methods in molecular biology. 1149. 681–688. 36 indexed citations

7.

Nadal‐Jimenez, Pol, Gudrun Koch, Jessica A. Thompson, et al.. (2012). The Multiple Signaling Systems Regulating Virulence in Pseudomonas aeruginosa. Microbiology and Molecular Biology Reviews. 76(1). 46–65. 551 indexed citations breakdown →

8.

Szegezdi, Éva, Carlos R. Reis, Almer M. van der Sloot, et al.. (2010). Targeting AML through DR4 with a novel variant of rhTRAIL. Journal of Cellular and Molecular Medicine. 15(10). 2216–2231. 19 indexed citations

9.

Duiker, Evelien W., Elisabeth G.E. de Vries, Devalingam Mahalingam, et al.. (2009). Enhanced Antitumor Efficacy of a DR5-Specific TRAIL Variant over Recombinant Human TRAIL in a Bioluminescent Ovarian Cancer Xenograft Model. Clinical Cancer Research. 15(6). 2048–2057. 41 indexed citations

10.

Sio, Charles F., Linda G. Otten, Robbert H. Cool, et al.. (2006). Quorum Quenching by an N -Acyl-Homoserine Lactone Acylase from Pseudomonas aeruginosa PAO1. Infection and Immunity. 74(3). 1673–1682. 244 indexed citations

11.

Sloot, Almer M. van der, Éva Szegezdi, Margaret M. Mullally, et al.. (2006). Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor. Proceedings of the National Academy of Sciences. 103(23). 8634–8639. 136 indexed citations

12.

Sio, Charles F., Linda G. Otten, Robbert H. Cool, & Wim J. Quax. (2003). Analysis of a substrate specificity switch residue of cephalosporin acylase. Biochemical and Biophysical Research Communications. 312(3). 755–760. 17 indexed citations

13.

Kraemer, Astrid, Holger Rehmann, Robbert H. Cool, et al.. (2001). Dynamic interaction of cAMP with the rap guanine-nucleotide exchange factor epac1. Journal of Molecular Biology. 306(5). 1167–1177. 58 indexed citations

14.

Görlach, Agnes, Isabel Diebold, Robbert H. Cool, et al.. (2000). Activation of hypoxia-inducible factor-1 is modulated by Rac1 in endothelial cells. Circulation. 102(18). 87–87. 1 indexed citations

15.

Rooij, Johan de, Holger Rehmann, Miranda van Triest, et al.. (2000). Mechanism of Regulation of the Epac Family of cAMP-dependent RapGEFs. Journal of Biological Chemistry. 275(27). 20829–20836. 324 indexed citations

16.

Bauer, Bettina, Gladys Mirey, Ingrid R. Vetter, et al.. (1999). Effector Recognition by the Small GTP-binding Proteins Ras and Ral. Journal of Biological Chemistry. 274(25). 17763–17770. 71 indexed citations

17.

Wolthuis, Rob M.F., Barbara Franke, Miranda van Triest, et al.. (1998). Activation of the Small GTPase Ral in Platelets. Molecular and Cellular Biology. 18(5). 2486–2491. 127 indexed citations

18.

Mistou, Michel‐Yves, Robbert H. Cool, & Andrea Parmeggiani. (1992). Effects of ions on the intrinsic activities of c‐H‐ras protein p21. European Journal of Biochemistry. 204(1). 179–185. 23 indexed citations

19.

Anborgh, Pieter H., Robbert H. Cool, K. Harmark, et al.. (1991). Structure-function relationships of elongation factor Tu as studied by mutagenesis. Biochimie. 73(7-8). 1051–1059. 9 indexed citations

20.

Zuidema, D., Robbert H. Cool, & E.M.J. Jaspars. (1984). Minimum requirements for specific binding of RNA and coat protein of alfalfa mosaic virus. Virology. 136(2). 282–292. 9 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact