Henning Walczak

43.7k total citations · 15 hit papers
207 papers, 26.5k citations indexed

About

Henning Walczak is a scholar working on Molecular Biology, Immunology and Cancer Research. According to data from OpenAlex, Henning Walczak has authored 207 papers receiving a total of 26.5k indexed citations (citations by other indexed papers that have themselves been cited), including 149 papers in Molecular Biology, 109 papers in Immunology and 58 papers in Cancer Research. Recurrent topics in Henning Walczak's work include Cell death mechanisms and regulation (106 papers), NF-κB Signaling Pathways (54 papers) and interferon and immune responses (47 papers). Henning Walczak is often cited by papers focused on Cell death mechanisms and regulation (106 papers), NF-κB Signaling Pathways (54 papers) and interferon and immune responses (47 papers). Henning Walczak collaborates with scholars based in Germany, United Kingdom and United States. Henning Walczak's co-authors include Peter H. Krammer, Klaus‐Michael Debatin, Jens Dhein, Andreas Linkermann, Eva Rieser, Caroline Bäumler, Martin R. Sprick, Silvia von Karstedt, Antonella Montinaro and Peter Vandenabeele and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and The Lancet.

In The Last Decade

Henning Walczak

204 papers receiving 26.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

1999 2.2k citations Henning Walczak et al. profile →
Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1995 1.5k citations Henning Walczak, Klaus‐Michael Debatin et al. Nature profile →
Regulated necrosis: the expanding network of non-apoptotic cell death pathways

2014 1.3k citations Andreas Linkermann, Henning Walczak et al. profile →
TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL

1997 972 citations Henning Walczak profile →
Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120

1995 844 citations Henning Walczak, Klaus‐Michael Debatin et al. Nature profile →
Linear ubiquitination prevents inflammation and regulates immune signalling

2011 725 citations Eva Rieser, Tobias L. Haas et al. Nature profile →
FADD/MORT1 and Caspase-8 Are Recruited to TRAIL Receptors 1 and 2 and Are Essential for Apoptosis Mediated by TRAIL Receptor 2

2000 678 citations Martin R. Sprick, Eva Rieser et al. profile →
Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

1997 653 citations Henning Walczak, Wolfgang Stremmel et al. profile →
CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes

2003 634 citations Henning Walczak et al. profile →
Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction

2009 596 citations Tobias L. Haas, Eva Rieser et al. profile →
Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage.

1995 586 citations Henning Walczak, Wolfgang Stremmel et al. The Journal of Experimental Medicine profile →
Cloning and Characterization of TRAIL-R3, a Novel Member of the Emerging TRAIL Receptor Family

1997 543 citations Henning Walczak et al. The Journal of Experimental Medicine profile →
The CD95 (APO-1/Fas) and the TRAIL (APO-2L) Apoptosis Systems

2000 507 citations Henning Walczak et al. profile →
Two independent pathways of regulated necrosis mediate ischemia–reperfusion injury

2013 452 citations Andreas Linkermann, Henning Walczak et al. Proceedings of the National Academy of Sciences profile →
Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy

2017 436 citations Silvia von Karstedt, Antonella Montinaro et al. profile →

Peers

Countries citing papers authored by Henning Walczak

Since Specialization

Citations

This map shows the geographic impact of Henning Walczak's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Henning Walczak with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Henning Walczak more than expected).

Fields of papers citing papers by Henning Walczak

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Henning Walczak. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Henning Walczak. The network helps show where Henning Walczak may publish in the future.

Co-authorship network of co-authors of Henning Walczak

This figure shows the co-authorship network connecting the top 25 collaborators of Henning Walczak. A scholar is included among the top collaborators of Henning Walczak based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Henning Walczak. Henning Walczak is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Deep immune profiling delineates hallmarks of disease heterogeneity in extrapulmonary tuberculosis 2025 ·Nature Communications ·Sebastian J. Theobald, K. Dahm, (unknown), (unknown), Sandra Winter, (unknown), Lisa Holsten, Alexander Simonis, Elena De Domenico, Henning Walczak, Martina van Uelft, Joachim L. Schultze, Marc Beyer, Thomas Ulas, (unknown), Jan Rybniker	0
2	STING induces ZBP1-mediated necroptosis independently of TNFR1 and FADD 2025 ·Nature ·(unknown), (unknown), (unknown), (unknown), Federica Locci, (unknown), (unknown), (unknown), Martin Peifer, (unknown), Antonella Montinaro, (unknown), Aleksandra Trifunović, Giusi Prencipe, Antonella Insalaco, Fabrizio De Benedetti, Henning Walczak, Gianmaria Liccardi	4
3	The importance of murine phospho-MLKL-S345 in situ detection for necroptosis assessment in vivo 2024 ·Cell Death and Differentiation ·(unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Iratxe Uranga-Murillo, Maykel Arias, Julián Pardo, Wulf Tonnus, Andreas Linkermann, Alessandro Annibaldi, Henning Walczak, Gianmaria Liccardi	6
4	Orbi‐SIMS Mediated Metabolomics Analysis of Pathogenic Tissue up to Cellular Resolution 2024 ·Chemistry - Methods ·(unknown), (unknown), (unknown), Mariia Yuneva, Henning Walczak, Gianmaria Liccardi, (unknown), Peter Kreuzaler, Marcus Rohnke	4
5	Laparoscopic ischemic conditioning of the stomach prior to esophagectomy induces gastric neo-angiogenesis 2023 ·European Journal of Surgical Oncology ·Lars M. Schiffmann, Esther de Groot, Michael Albert, Alexander Quaas, Daniel Pinto dos Santos, Benjamin Babic, Hans F. Fuchs, Henning Walczak, Seung‐Hun Chon, Jelle P. Ruurda, Hamid Kashkar, Christiane J. Bruns, Wolfgang Schröder, Richard van Hillegersberg	2
6	A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets 2022 ·Proceedings of the National Academy of Sciences ·(unknown), Chun‐Hao Huang, Francisco J. Sánchez‐Rivera, Margaret C. Kennedy, Darjus F. Tschaharganeh, John P. Morris, Antonella Montinaro, Kevin P. O’Rourke, Ana Banito, John E. Wilkinson, Chi-Chao Chen, Yu-Jui Ho, Lukas E. Dow, Sha Tian, Wei Luan, Elisa de Stanchina, Tinghu Zhang, Nathanael S. Gray, Henning Walczak, Scott W. Lowe	8
7	TRAIL-receptor 2—a novel negative regulator of p53 2021 ·Cell Death and Disease ·(unknown), (unknown), (unknown), (unknown), (unknown), Torsten Hartwig, (unknown), Jürgen Fritsch, Steven Singh, Henning Walczak, Silvia von Karstedt, H. Schäfer, Anna Trauzold	10
8	RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury 2019 ·Cell Death and Differentiation ·(unknown), Stephan Singer, Marietta Armaka, Jesús M. Bañales, Kerstin Hölzer, Peter Schirmacher, Henning Walczak, George Kollias, Manolis Pasparakis, Vangelis Kondylis	25
9	TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation 2018 ·Nature Cell Biology ·Élodie Lafont, Peter Dráber, Eva Rieser, Matthias Reichert, Sebastian Kupka, Diego de Miguel, Helena Draberova, Anne von Mäßenhausen, Amandeep Bhamra, Stephen Henderson, Katarzyna Wojdyła, (unknown), Silvia Šurinová, Andreas Linkermann, Henning Walczak	205
10	CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling 2009 ·The Journal of Experimental Medicine ·Gudrun Strauß, Jonathan A. Lindquist, Nathalie J. Arhel, Edward Felder, Sabine Karl, Tobias L. Haas, Simone Fulda, Henning Walczak, Frank Kirchhoff, Klaus‐Michael Debatin	28
11	Small Molecule XIAP Inhibitors Enhance TRAIL-Induced Apoptosis and Antitumor Activity in Preclinical Models of Pancreatic Carcinoma 2009 ·Cancer Research ·Meike Vogler, Henning Walczak, Dominic Stadel, Tobias L. Haas, Felicitas Genze, (unknown), Umesh Bhanot, Cornelia Hasel, Peter Möller, Jürgen E. Gschwend, Thomas Simmet, Klaus‐Michael Debatin, Simone Fulda	121
12	Prognostic Value of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (TRAIL) and TRAIL Receptors in Renal Cell Cancer 2009 ·Clinical Cancer Research ·Stephan Macher‐Goeppinger, Sebastian Aulmann, Katrin E. Tagscherer, Nina Wagener, Axel Haferkamp, Roland Penzel, (unknown), Markus Hohenfellner, Jaromir Sykora, Henning Walczak, Bin Tean Teh, Frank Autschbach, Esther Herpel, Peter Schirmacher, Wilfried Roth	56
13	Targeting XIAP Bypasses Bcl-2–Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo 2008 ·Cancer Research ·Meike Vogler, Henning Walczak, Dominic Stadel, Tobias L. Haas, Felicitas Genze, (unknown), Jürgen E. Gschwend, Thomas Simmet, Klaus‐Michael Debatin, Simone Fulda	135
14	Lidocaine Induces Apoptosis via the Mitochondrial Pathway Independently of Death Receptor Signaling 2007 ·Anesthesiology ·Robert Werdehausen, Sebastian Braun, Frank Eßmann, Klaus Schulze‐Osthoff, Henning Walczak, P. Lipfert, Markus F. Stevens	111
15	TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window 2007 ·Hepatology ·Ronald Koschny, Tom M. Ganten, Jaromir Sykora, Tobias L. Haas, Martin R. Sprick, Armin Kolb, Wolfgang Stremmel, Henning Walczak	102
16	Proteasome Inhibition Results in TRAIL Sensitization of Primary Keratinocytes by Removing the Resistance-Mediating Block of Effector Caspase Maturation 2003 ·Molecular and Cellular Biology ·Martin Leverkus, Martin R. Sprick, (unknown), Thilo Mengling, Bernd Baumann, Edgar Serfling, (unknown), Matthias Goebeler, Manfred Neumann, Henning Walczak	3
17	TNF-Related Apoptosis-Inducing Ligand Mediates Tumoricidal Activity of Human Monocytes Stimulated by Newcastle Disease Virus 2003 ·The Journal of Immunology ·(unknown), Markus A. Weigand, Anne Große-Wilde, Markus Janke, Heiko Stahl, Eva Rieser, Martin R. Sprick, Volker Schirrmacher, Henning Walczak	93
18	The interplay between the Bcl-2 family and death receptor-mediated apoptosis 2003 ·Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·Martin R. Sprick, Henning Walczak	178
19	TRAIL enhances thymidine kinase/ganciclovir gene therapy of neuroblastoma cells 2002 ·Cancer Gene Therapy ·Christian Beltinger, Simone Fulda, Henning Walczak, Klaus‐Michael Debatin	17
20	Cutting Edge: Resistance to Apoptosis and Continuous Proliferation of Dendritic Cells Deficient for TNF Receptor-1 2000 ·The Journal of Immunology ·Jens Oliver Funk, Henning Walczak, (unknown), Susanne Berchtold, Thomas Baumeister, Pia Rauch, Susanne Rößner, Alexander Steinkasserer, Gerold Schuler, Manfred B. Lutz	30

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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