Klaus Schulze‐Osthoff

37.3k total citations · 8 hit papers
311 papers, 29.8k citations indexed

About

Klaus Schulze‐Osthoff is a scholar working on Molecular Biology, Immunology and Oncology. According to data from OpenAlex, Klaus Schulze‐Osthoff has authored 311 papers receiving a total of 29.8k indexed citations (citations by other indexed papers that have themselves been cited), including 198 papers in Molecular Biology, 97 papers in Immunology and 62 papers in Oncology. Recurrent topics in Klaus Schulze‐Osthoff's work include Cell death mechanisms and regulation (105 papers), NF-κB Signaling Pathways (45 papers) and Immune Response and Inflammation (31 papers). Klaus Schulze‐Osthoff is often cited by papers focused on Cell death mechanisms and regulation (105 papers), NF-κB Signaling Pathways (45 papers) and Immune Response and Inflammation (31 papers). Klaus Schulze‐Osthoff collaborates with scholars based in Germany, United States and France. Klaus Schulze‐Osthoff's co-authors include Sebastian Wesselborg, Marek Łoś, Reiner U. Jänicke, Wulf Dröge, Davide Ferrari, Frank Eßmann, Ute Fischer, Christian Schwerk, Christopher Stroh and Heike Schenk and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Klaus Schulze‐Osthoff

306 papers receiving 29.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Many cuts to ruin: a comprehensive update of caspase substrates

2003 852 citations Reiner U. Jänicke, Klaus Schulze‐Osthoff et al. profile →
Apoptosis signaling by death receptors

1998 815 citations Klaus Schulze‐Osthoff, Marek Łoś et al. profile →
Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation.

1992 811 citations Klaus Schulze‐Osthoff et al. Journal of Biological Chemistry profile →
Apoptotic Cells Induce Migration of Phagocytes via Caspase-3-Mediated Release of a Lipid Attraction Signal

2003 756 citations Kirsten Lauber, Klaus Schulze‐Osthoff et al. profile →
Distinct effects of thioredoxin and antioxidants onthe activation of transcription factors NF-kappa B and AP-1.

1994 589 citations Wulf Dröge, Klaus Schulze‐Osthoff et al. profile →
Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

1995 567 citations Marek Łoś, Wulf Dröge et al. profile →
Small Stress Proteins as Novel Regulators of Apoptosis

1996 533 citations Klaus Schulze‐Osthoff et al. Journal of Biological Chemistry profile →
Transdifferentiation of Vascular Smooth Muscle Cells to Macrophage-Like Cells During Atherogenesis

2014 413 citations Frank Eßmann, Klaus Schulze‐Osthoff et al. profile →

Peers

Countries citing papers authored by Klaus Schulze‐Osthoff

Since Specialization

Citations

This map shows the geographic impact of Klaus Schulze‐Osthoff's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Klaus Schulze‐Osthoff with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Klaus Schulze‐Osthoff more than expected).

Fields of papers citing papers by Klaus Schulze‐Osthoff

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Klaus Schulze‐Osthoff. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Klaus Schulze‐Osthoff. The network helps show where Klaus Schulze‐Osthoff may publish in the future.

Co-authorship network of co-authors of Klaus Schulze‐Osthoff

This figure shows the co-authorship network connecting the top 25 collaborators of Klaus Schulze‐Osthoff. A scholar is included among the top collaborators of Klaus Schulze‐Osthoff based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Klaus Schulze‐Osthoff. Klaus Schulze‐Osthoff is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Constitutive expression of the transcriptional co-activator IκBζ promotes melanoma growth and immunotherapy resistance 2025 ·Nature Communications ·(unknown), (unknown), Matthias Klein, (unknown), Maximilian Haist, (unknown), (unknown), Tobias Sinnberg, Antje Sucker, (unknown), (unknown), Alpaslan Tasdogan, Andrea Tuettenberg, Matthias M. Gaida, Carsten Deppermann, Henner Stege, Dirk Schadendorf, Stephan Grabbe, Klaus Schulze‐Osthoff, (unknown)	0
2	BRD4 inhibition sensitizes diffuse large B-cell lymphoma cells to ferroptosis 2023 ·Blood ·Anja Schmitt, Melanie Grimm, (unknown), (unknown), (unknown), (unknown), Caroline Schönfeld, (unknown), (unknown), Kerstin Menck, Annalen Bleckmann, Claudia Lengerke, Frank Rosenbauer, Michael Grau, Mattia Zampieri, Klaus Schulze‐Osthoff, Pavel Klener, (unknown), Georg Lenz, Stephan Hailfinger	38
3	Hepatokine‐based identification of fibrotic NASH and improved risk stratification in a multicentre cohort of NAFLD patients 2023 ·Liver International ·Martin Franck, Katharina John, (unknown), Monika Rau, Andreas Geier, Jörn M. Schattenberg, Heiner Wedemeyer, Klaus Schulze‐Osthoff, Heike Bantel	6
4	Non-Invasive Detection of Fibrotic NASH in NAFLD Patients with Low or Intermediate FIB-4 2022 ·Journal of Clinical Medicine ·Katharina John, Martin Franck, (unknown), Monika Rau, Yvonne Huber, Jörn M. Schattenberg, Andreas Geier, Mathias Bähr, Heiner Wedemeyer, Klaus Schulze‐Osthoff, Heike Bantel	7
5	Distinct immune evasion in APOBEC ‐enriched, HPV ‐negative HNSCC 2020 ·International Journal of Cancer ·(unknown), Benedikt Obermayer, Konrad Klinghammer, Sebastian Ochsenreither, Denise Treue, Albrecht Stenzinger, Hanno Glimm, Stefan Fröhling, Thomas Kindler, Christian Brandts, Klaus Schulze‐Osthoff, Wilko Weichert, Ingeborg Tinhofer, Frederick Klauschen, Ulrich Keilholz, Dieter Beule, Damian Rieke	12
6	Targeting chronic NFAT activation with calcineurin inhibitors in diffuse large B-cell lymphoma 2019 ·Blood ·Philip Bucher, Tabea Erdmann, (unknown), Wendan Xu, Anja Schmitt, (unknown), Myroslav Zapukhlyak, Caroline Schönfeld, Edgar Serfling, Daniela Kramer, Michael Grau, Pavel Klener, Claudia Lengerke, Klaus Schulze‐Osthoff, Georg Lenz, Stephan Hailfinger	27
7	Prominent Oncogenic Roles of EVI1 in Breast Carcinoma 2017 ·Cancer Research ·Hui Wang, Thorsten Schaefer, Martina Konantz, Martin Braun, Zsuzsanna Varga, Anna Paczulla, Selina Reich, Francis Jacob, Sven Perner, Holger Moch, Tanja Fehm, Lothar Kanz, Klaus Schulze‐Osthoff, Claudia Lengerke	31
8	The Atypical Inhibitor of NF-kappa B, I kappa B zeta, Controls Macrophage Interleukin-10 Expression 2016 ·Journal of Biological Chemistry ·(unknown), Stephan Hailfinger, Klaus Schulze‐Osthoff, Frank Eßmann, Sebastian Hörber, Dominic G. Hildebrand, Wolfgang Lieb	1
9	Differential Induction of Apoptosis and Senescence by the DNA Methyltransferase Inhibitors 5-Azacytidine and 5-Aza-2′-Deoxycytidine in Solid Tumor Cells 2013 ·Molecular Cancer Therapeutics ·Sascha Venturelli, Alexander Berger, Timo Weiland, Frank Eßmann, Michaela Waibel, Tina Nuebling, Sabine Häcker, Martin Schenk, Klaus Schulze‐Osthoff, Helmut R. Salih, Simone Fulda, Bence Sipos, Ricky W. Johnstone, Ulrich M. Lauer, Michael Bitzer	86
10	SOX2 Expression Associates with Stem Cell State in Human Ovarian Carcinoma 2013 ·Cancer Research ·Petra M. Bareiss, Anna Paczulla, Hui Wang, Rebekka Schairer, Stefan Wiehr, Ursula Kohlhofer, Oliver C. Rothfuss, Anna Fischer, Sven Perner, Annette Staebler, D. Wallwiener, Falko Fend, Tanja Fehm, Bernd J. Pichler, Lothar Kanz, Leticia Quintanilla-Martı́nez, Klaus Schulze‐Osthoff, Frank Eßmann, Claudia Lengerke	126
11	I kappa B zeta Is a Transcriptional Key Regulator of CCL2/MCP-1 2013 ·The Journal of Immunology ·Dominic G. Hildebrand, Eva Alexander, (unknown), Simon Lehle, (unknown), (unknown), Oliver C. Rothfuss, Julia-Stefanie Frick, Masami Morimatsu, Ingo Schmitz, (unknown), Jan Ehrchen, Frank Eßmann, Klaus Schulze‐Osthoff	3
12	Mechanisms of Cell Death in Acute Liver Failure 2012 ·Frontiers in Physiology ·Heike Bantel, Klaus Schulze‐Osthoff	89
13	Thioredoxin in human and experimental sepsis* 2009 ·Critical Care Medicine ·Stefan Hofer, (unknown), Hajime Nakamura, Junji Yodoi, Christian Bopp, Johannes B. Zimmermann, (unknown), Peter Schemmer, (unknown), Klaus Schulze‐Osthoff, Raoul Breitkreutz, Markus A. Weigand	29
14	Cell Surface Externalization of Annexin A1 as a Failsafe Mechanism Preventing Inflammatory Responses during Secondary Necrosis 2009 ·The Journal of Immunology ·(unknown), Szabolcs Soeroes, Michaela Waibel, Hildegard Keppeler, Sebastian Wesselborg, Martin Herrmann, Klaus Schulze‐Osthoff, Kirsten Lauber	65
15	Cancer stem cell markers in common cancers – therapeutic implications 2008 ·Trends in Molecular Medicine ·Thomas Klonisch, Emilia Wiecheć, Sabine Hombach‐Klonisch, Sudharsana Rao Ande, Sebastian Wesselborg, Klaus Schulze‐Osthoff, Marek Łoś	321
16	Lidocaine Induces Apoptosis via the Mitochondrial Pathway Independently of Death Receptor Signaling 2007 ·Anesthesiology ·Robert Werdehausen, Sebastian Braun, Frank Eßmann, Klaus Schulze‐Osthoff, Henning Walczak, P. Lipfert, Markus F. Stevens	111
17	p21 Blocks Irradiation-Induced Apoptosis Downstream of Mitochondria by Inhibition of Cyclin-Dependent Kinase–Mediated Caspase-9 Activation 2006 ·Cancer Research ·Dennis Sohn, Frank Eßmann, Klaus Schulze‐Osthoff, Reiner U. Jänicke	103
18	Role of the CD95/CD95 Ligand System in Glucocorticoid-Induced Monocyte Apoptosis 2001 ·The Journal of Immunology ·Michael Schmidt, Norbert Lügering, Andreas Lügering, Hans‐Gerd Pauels, Klaus Schulze‐Osthoff, W Domschke, Torsten Kucharzik	56
19	Enhancement of T Cell Receptor Signaling by a Mild Oxidative Shift in the Intracellular Thiol Pool 2000 ·The Journal of Immunology ·Steffen P. Hehner, Raoul Breitkreutz, George Shubinsky, (unknown), Klaus Schulze‐Osthoff, M. Lienhard Schmitz, Wulf Dröge	134
20	転写因子NF‐κBとAP‐1の活性化に及ぼすチオレドキシンと抗酸化剤の異なった効果 1994 ·Proc Natl Acad Sci USA ·(unknown), (unknown), (unknown), (unknown), Klaus Schulze‐Osthoff	228

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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