David Stokoe

24.5k citations

96 papers · 15.7k indexed · 8 hit papers · h-index 53

Impact in

Genetics top 0.2%
- Glioma Diagnosis and Treatment
Molecular Biology top 0.2%
- PI3K/AKT/mTOR signaling in cancer
- Protein Kinase Regulation and GTPase Signaling
- Melanoma and MAPK Pathways

Papers in

Molecular Biology 84
- PI3K/AKT/mTOR signaling in cancer 46
- Protein Kinase Regulation and GTPase Signaling 24
- Melanoma and MAPK Pathways 12
- Cell death mechanisms and regulation 5
- Protein Degradation and Inhibitors 5
- DNA Repair Mechanisms 4
Genetics 9

Co-authors: Frank McCormick Phillip T. Hawkins Len Stephens Marc Symons Larry Kane Arthur Weiss Daphne A. Haas‐Kogan Andrew B. Holmes
Journals: Biochemical Journal (9 papers)Current Biology (6 papers)Molecular and Cellular Biology (6 papers)Journal of Biological Chemistry (4 papers)Cancer Research (4 papers)
Partner nations: United States United Kingdom France

In The Last Decade

David Stokoe

95 papers receiving 15.4k citations

Hit Papers

8 papers align trajectories log scale

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity 2012 · 479 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2012 Proceedings of the National Academy of Sciences
2006 Cell
2006 Nature Medicine
2000 Genes & Development
1999 Current Biology
1998 Science
1997 Science
1994 Science

Peers

Countries citing papers authored by David Stokoe

Since Specialization

Citations

This map shows the geographic impact of David Stokoe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Stokoe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Stokoe more than expected).

Fields of papers citing papers by David Stokoe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Stokoe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Stokoe. The network helps show where David Stokoe may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David Stokoe, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David Stokoe Line = papers co-authored together David Stokoe links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	BiDAC-dependent degradation of plasma membrane proteins by the endolysosomal system Nature Communications ·William P. S. Mckay, 英器本山, 史格斯, Nguyen Hoang Chung, Niclas Olsson, Austin E.Y.T. Lefebvre, Mark E. Fitzgerald, Katrina L. Jackson, B Privett, Brian Y. Feng, Aaron H. Nile, David Stokoe, Kirill Bersuker	2025	1
2	Inhibition of Aurora Kinase Induces Endogenous Retroelements to Induce a Type I/III IFN Response via RIG-I Cancer Research Communications ·Lisa Choy, Stephen R. Norris, Xiumin Wu, Ganesh Kolumam, Ari J. Firestone, Jeffrey Settleman, David Stokoe	2024	4
3	Ras–MEK Signaling Mediates a Critical Chk1-Dependent DNA Damage Response in Cancer Cells Molecular Cancer Therapeutics ·Ho-June Lee, Yi Cao, Victoria C. Pham, Elizabeth Blackwood, Catherine Wilson, Marie Evangelista, Christiaan Klijn, David Stokoe, Jeff Settleman	2017	16
4	Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes Cancer Research ·John P. McGrath, Kaylyn E. Williamson, Srividya Balasubramanian, Shobu Odate, Shilpi Arora, Charlie Hatton, Thomas M. Edwards, Thomas O’Brien, Steven Magnuson, David Stokoe, Danette L. Daniels, Barbara M. Bryant, Patrick Trojer	2016	70
5	The relationship between malnutrition risk and clinical outcomes in a cohort of frail older hospital patients Clinical Nutrition ESPEN ·Adrian Slee, C. Mascarella, David Stokoe	2016	30
6	Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes Cancer Research ·Genee Y. Lee, Peter M. Haverty, Li Li, Noelyn M. Kljavin, Richard Bourgon, James Lee, Howard M. Stern, Zora Modrušan, Somasekar Seshagiri, Zemin Zhang, A Atabo, David Stokoe, Jeffrey Settleman, Frédéric J. de Sauvage, Richard M. Neve	2014	125
7	Selective Inhibition of Mutant Ras Protein through Covalent Binding Angewandte Chemie International Edition ·Joachim Rudolph, David Stokoe	2014	26
8	Oncogenic Activating Mutations Are Associated with Local Copy Gain Molecular Cancer Research ·Barmak Modrek, Lin Ge, Ajay Pandita, Eva Lin, Sankar Mohan, Peng Yue, Steve Guerrero, William M. Lin, Thinh Q. Pham, Zora Modrušan, Somasekar Seshagiri, Howard M. Stern, Paul Waring, Levi A. Garraway, John Chant, David Stokoe, Guy Cavet	2009	51
9	Genetic Alterations and Oncogenic Pathways Associated with Breast Cancer Subtypes Molecular Cancer Research ·Xiaolan Hu, Howard M. Stern, Lin Ge, Carol O’Brien, Lauren E. Haydu, Gallaba Mudiyanselage Anuradha Dhananjaya, Peter M. Haverty, Brock A. Peters, Thomas D. Wu, Lukas C. Amler, John Chant, David Stokoe, Mark R. Lackner, Guy Cavet	2009	177
10	Activation of PI3K/mTOR pathway occurs in most adult low-grade gliomas and predicts patient survival Journal of Neuro-Oncology ·Sean M. McBride, Daniel Pérez, Mei‐Yin C. Polley, Scott R. VandenBerg, Justin S. Smith, Shichun Zheng, Kathleen R. Lamborn, John K. Wiencke, Susan M. Chang, Michael D. Prados, Mitchel S. Berger, David Stokoe, Daphne A. Haas-Kogan	2009	59
11	PIK3CA Cooperates with Other Phosphatidylinositol 3′-Kinase Pathway Mutations to Effect Oncogenic Transformation Cancer Research ·Katsutoshi Oda, Sun Liqin, Luika Timmerman, Pablo Rodriguez‐Viciana, David Stokoe, Keiko Shoji, Yuji Taketani, Hiroyuki Kuramoto, Zachary A. Knight, Kevan M. Shokat, Frank McCormick	2008	136
12	Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells Experimental Cell Research ·Tanja Tamgüney, Chao Zhang, Dorothea Fiedler, Kevan M. Shokat, David Stokoe	2008	25
13	Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma Neuro-Oncology ·John K. Wiencke, Shichun Zheng, Allen Ao Guo, Tarık Tihan, Scott R. VandenBerg, Tanja Tamgüney, Júlio Flávio Conrado Santos, Ramon Parsons, Kathleen R. Lamborn, Mitchel S. Berger, Margaret Wrensch, Daphne A. Haas-Kogan, David Stokoe	2007	123
14	mTOR-Independent Translational Control of the Extrinsic Cell Death Pathway by RalA Molecular and Cellular Biology ·Amith Panner, Jean L. Nakamura, Andrew T. Parsa, Pablo Rodriguez‐Viciana, Mitchel S. Berger, David Stokoe, Russell O. Pieper	2006	23
15	High Frequency of Coexistent Mutations of PIK3CA and PTEN Genes in Endometrial Carcinoma Cancer Research ·Katsutoshi Oda, David Stokoe, Yuji Taketani, Frank McCormick	2005	345
16	ZNF217 suppresses cell death associated with chemotherapy and telomere dysfunction Human Molecular Genetics ·Guiqing Huang, Sheryl R. Krig, David Kowbel, Hongmei Xu, Joseph McComb, Stas Volik, Burt G. Feuerstein, Gordon B. Mills, David Stokoe, Paul Yaswen, Colin C. Collins	2005	53
17	Adenovirus Overrides Cellular Checkpoints for Protein Translation Cell Cycle ·Clodagh C. O’Shea, Serah Choi, Frank McCormick, David Stokoe	2005	39
18	Phosphorylation of p16 Correlates with Cdk4 Association Journal of Biological Chemistry ·三四吾木村, David Stokoe, Frank McCormick	2003	35
19	Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival Current Biology ·Peter F. Flynn, M. Guru Prasad, 李广文, Nicholas M. Dean, David Stokoe	2000	73
20	Regulation of Tiam1 Nucleotide Exchange Activity by Pleckstrin Domain Binding Ligands Journal of Biological Chemistry ·Anne Crompton, Louise H. Foley, Alexander W. Wood, Telukuntla Naga Vijayeswara Sailesh, David Stokoe, Frank McCormick, Marc Symons, Gideon Bollag	2000	46

About David Stokoe

David Stokoe is a scholar working on Molecular Biology, Genetics, Oncology, Geriatrics and Gerontology and Cell Biology, having authored 96 papers that have together received 15.7k indexed citations. Recurring topics across this work include PI3K/AKT/mTOR signaling in cancer (46 papers), Protein Kinase Regulation and GTPase Signaling (24 papers), Melanoma and MAPK Pathways (12 papers), Cancer Mechanisms and Therapy (11 papers), Cancer-related Molecular Pathways (10 papers), Cell death mechanisms and regulation (5 papers), Protein Degradation and Inhibitors (5 papers) and DNA Repair Mechanisms (4 papers). The work is most often cited by research in Genetics (1.8k citations), Molecular Biology (11.5k citations), Cancer Research (2.5k citations), Oncology (3.5k citations) and Immunology (2.1k citations). David Stokoe has collaborated with scholars based in United States, United Kingdom and France. Frequent co-authors include Frank McCormick, Phillip T. Hawkins, Len Stephens, Marc Symons, Larry Kane, Arthur Weiss, Daphne A. Haas‐Kogan, Andrew B. Holmes, Gavin F. Painter and Piers R. J. Gaffney. Their work appears in journals such as Biochemical Journal, Current Biology, Molecular and Cellular Biology, Journal of Biological Chemistry and Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact