Channing J. Der

71.6k citations

406 papers · 48.3k indexed · 18 hit papers · h-index 111

Impact in

Cell Biology top 0.01%
- Cellular transport and secretion
- Cellular Mechanics and Interactions
Molecular Biology top 0.02%
- Protein Kinase Regulation and GTPase Signaling
- PI3K/AKT/mTOR signaling in cancer
- Melanoma and MAPK Pathways
- Cell death mechanisms and regulation

Papers in

Cell Biology 85
- Cellular transport and secretion 27
Molecular Biology 348
- Protein Kinase Regulation and GTPase Signaling 223
- Melanoma and MAPK Pathways 86
- PI3K/AKT/mTOR signaling in cancer 73
- Cell death mechanisms and regulation 71
- Ubiquitin and proteasome pathways 25

Co-authors: Adrienne D. Cox Kent L. Rossman Patrick J. Roberts Roya Khosravi‐Far Patricia A. Solski Geoffrey Clark Krister Wennerberg John Sondek
Journals: Journal of Biological Chemistry (72 papers)Molecular and Cellular Biology (41 papers)Proceedings of the National Academy of Sciences (21 papers)Methods in enzymology on CD-ROM/Methods in enzymology (20 papers)Cancer Research (18 papers)
Partner nations: United States Germany Australia

In The Last Decade

Channing J. Der

390 papers receiving 47.4k citations

Hit Papers

15 papers align trajectories log scale

KRAS inhibitors: resistance drivers and combinatorial strategies 2024 · 52 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2024 Trends in cancer
2017 Cold Spring Harbor Perspectives in Medicine
2016 Journal of Cell Science
2014 Nature Reviews Drug Discovery
2014 Trends in Biochemical Sciences
2010 Small GTPases
2010 Nature reviews. Cancer
2007 Oncogene
2005 Journal of Cell Science
2005 Nature Reviews Molecular Cell Biology
2000 Trends in Cell Biology
1998 Oncogene
1997 Science
1997 Nature
1995 Molecular and Cellular Biology
1993 Cell
1989 Proceedings of the National Academy of Sciences
1982 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Channing J. Der

Since Specialization

Citations

This map shows the geographic impact of Channing J. Der's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Channing J. Der with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Channing J. Der more than expected).

Fields of papers citing papers by Channing J. Der

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Channing J. Der. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Channing J. Der. The network helps show where Channing J. Der may publish in the future.

Co-authors

The 25 scholars most cited alongside Channing J. Der, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Channing J. Der Line = papers co-authored together Channing J. Der links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	“Undruggable KRAS”: druggable after all Genes & Development ·Adrienne D. Cox, Channing J. Der	2024	6
2	Concurrent Inhibition of ERK and Farnesyltransferase Suppresses the Growth of HRAS Mutant Head and Neck Squamous Cell Carcinoma Molecular Cancer Therapeutics ·Maud Z Muosieyiri, Antje Schaefer, Craig M. Goodwin, ヨシカズナガイ, Courtney Castronovo, Mariaelena Pierobon, 森健吉, Andrew M. Waters, S. Kriplani, J. Nathaniel Diehl, G. Aaron Hobbs, Kris C. Wood, Emanuel F. Petricoin, Channing J. Der, Adrienne D. Cox	2022	10
3	Phase Ib Study of Ulixertinib Plus Gemcitabine and Nab-Paclitaxel in Patients with Metastatic Pancreatic Adenocarcinoma The Oncologist ·Patrick Grierson, Benjamin Tan, Katrina S. Pedersen, Haeseong Park, Rama Suresh, Manik Amin, Nikolaos A. Trikalinos, Deborah Knoerzer, Brent L. Kreider, Anupama Reddy, Jingxia Liu, Channing J. Der, Andrea Wang‐Gillam, Kian‐Huat Lim	2022	24
4	Silencing of Oncogenic KRAS by Mutant-Selective Small Interfering RNA ACS Pharmacology & Translational Science ·Bjoern Papke, Salma H. Azam, Puruṣottamacaraṇagosvāmin, Raegen Schott, Duane Altheide, Pradeep S. Pallan, Amanda E.D. Van Swearingen, Martin Egli, Adrienne D. Cox, Channing J. Der, Chad V. Pecot	2021	10
5	The ERK mitogen-activated protein kinase signaling network: the final frontier in RAS signal transduction Biochemical Society Transactions ·Jennifer E. Klomp, Jeffrey A. Klomp, Channing J. Der	2021	30
6	Analysis of RAS protein interactions in living cells reveals a mechanism for pan-RAS depletion by membrane-targeted RAS binders Proceedings of the National Academy of Sciences ·CATHERINE MORGAN, Nikki K. Lytle, Seth T. Gammon, Amanda de Farias Santos, Tikvah K. Hayes, Margie N. Sutton, Robert C. Bast, Channing J. Der, David Piwnica‐Worms, Frank McCormick, Geoffrey M. Wahl	2020	12
7	ERK/MAPK Signaling Drives Overexpression of the Rac-GEF, PREX1, in BRAF- and NRAS-Mutant Melanoma Molecular Cancer Research ·Meagan B. Ryan, Alexander J. Finn, Sajjad M. Yousafzai, Nancy E. Thomas, Channing J. Der, Adrienne D. Cox	2016	28
8	Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers Cancer Research ·Campbell D. Lawson, Cheng Fan, Natalia Mitin, Nicole M. Baker, Samuel D. George, David M. Graham, Charles M. Perou, Keith Burridge, Channing J. Der, Kent L. Rossman	2016	61
9	Response to MLN8237 in Pancreatic Cancer Is Not Dependent on RalA Phosphorylation Molecular Cancer Therapeutics ·Nicole F. Neel, Jeran K. Stratford, Vaishali Shinde, Jeffrey Ecsedy, Timothy D. Martin, Channing J. Der, Jen Jen Yeh	2013	14
10	Mutant N-RAS Protects Colorectal Cancer Cells from Stress-Induced Apoptosis and Contributes to Cancer Development and Progression Cancer Discovery ·Yufang Wang, Sérgia Velho, Efsevia Vakiani, Shouyong Peng, Adam J. Bass, Gerald C. Chu, Jessica J. Gierut, James M. Bugni, Channing J. Der, Mark R. Philips, David B. Solit, Kevin M. Haigis	2012	42
11	ROCK1 and ROCK2 Are Required for Non-Small Cell Lung Cancer Anchorage-Independent Growth and Invasion Cancer Research ·Dominico Vigil, Tai Young Kim, Alfred M. Lubell, Andrew J. Garton, Jianbo Jian, Jonathan A. Pachter, Hanqing Dong, Xin Chen, Georges Hervé, Sharon L. Campbell, Channing J. Der	2012	109
12	Activation and Involvement of Ral GTPases in Colorectal Cancer Cancer Research ·Timothy D. Martin, Jonathan C. Samuel, Elizabeth D. Routh, Channing J. Der, Jen Jen Yeh	2011	70
13	K-Ras Promotes Angiogenesis Mediated by Immortalized Human Pancreatic Epithelial Cells through Mitogen-Activated Protein Kinase Signaling Pathways Molecular Cancer Research ·Yoichi Matsuo, Paul M. Campbell, Rolf A. Brekken, Bokyung Sung, Michel M. Ouellette, Jason B. Fleming, Bharat B. Aggarwal, Channing J. Der, Sushovan Guha	2009	68
14	K-Ras Promotes Growth Transformation and Invasion of Immortalized Human Pancreatic Cells by Raf and Phosphatidylinositol 3-Kinase Signaling Cancer Research ·Paul M. Campbell, Yasuo Mimura, Kwang M. Lee, Michel M. Ouellette, Vladimir Khazak, Channing J. Der	2007	171
15	Lack of Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Signaling Shows a New Type of Melanoma Cancer Research ·Janiel M. Shields, Nancy E. Thomas, Melissa A. Cregger, Aaron J. Berger, Renny Amelia, Chad Torrice, Honglin Hao, Shannon Penland, Jack L. Arbiser, Glynis Scott, Tong Zhou, Menashe Bar‐Eli, James E. Bear, Channing J. Der, William K. Kaufmann, David L. Rimm, Norman E. Sharpless	2007	66
16	GTPases regulating membrane dynamics Elsevier eBooks ·William E. Balch, Channing J. Der, Andrew G. Hall	2005	1
17	Role of MLK3-mediated Activation of p70 S6 Kinase in Rac1 Transformation Journal of Biological Chemistry ·John M. Lambert, Antoine E. Karnoub, Lee M. Graves, Sharon L. Campbell, Channing J. Der	2002	19
18	Critical but Distinct Roles for the Pleckstrin Homology and Cysteine-Rich Domains as Positive Modulators of Vav2 Signaling and Transformation Molecular and Cellular Biology ·Michelle A. Booden, Sharon L. Campbell, Channing J. Der	2002	40
19	[40] Biological assays for Ras transformation Methods in enzymology on CD-ROM/Methods in enzymology ·Geoffrey Clark, Adrienne D. Cox, Suzanne Graham, Channing J. Der	1995	179
20	[23] Transcriptional activation analysis of oncogene function Methods in enzymology on CD-ROM/Methods in enzymology ·Craig A. Hauser, Channing J. Der, Adrienne D. Cox	1994	11

About Channing J. Der

Channing J. Der is a scholar working on Cell Biology, Molecular Biology, Oncology, Aging and Immunology and Allergy, having authored 406 papers that have together received 48.3k indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (223 papers), Melanoma and MAPK Pathways (86 papers), PI3K/AKT/mTOR signaling in cancer (73 papers), Cell death mechanisms and regulation (71 papers), Cancer-related Molecular Pathways (68 papers), Cellular transport and secretion (27 papers), Ubiquitin and proteasome pathways (25 papers) and Pancreatic and Hepatic Oncology Research (22 papers). The work is most often cited by research in Cell Biology (10.6k citations), Molecular Biology (36.2k citations), Immunology and Allergy (2.9k citations), Oncology (12.7k citations) and Cancer Research (6.1k citations). Channing J. Der has collaborated with scholars based in United States, Germany and Australia. Frequent co-authors include Adrienne D. Cox, Kent L. Rossman, Patrick J. Roberts, Roya Khosravi‐Far, Patricia A. Solski, Geoffrey Clark, Krister Wennerberg, John Sondek, Sharon L. Campbell and Geoffrey M. Cooper. Their work appears in journals such as Journal of Biological Chemistry, Molecular and Cellular Biology, Proceedings of the National Academy of Sciences, Methods in enzymology on CD-ROM/Methods in enzymology and Cancer Research.

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