Alex G. Papageorge

6.8k total citations · 3 hit papers
53 papers, 5.4k citations indexed

About

Alex G. Papageorge is a scholar working on Molecular Biology, Cell Biology and Genetics. According to data from OpenAlex, Alex G. Papageorge has authored 53 papers receiving a total of 5.4k indexed citations (citations by other indexed papers that have themselves been cited), including 43 papers in Molecular Biology, 11 papers in Cell Biology and 11 papers in Genetics. Recurrent topics in Alex G. Papageorge's work include Protein Kinase Regulation and GTPase Signaling (15 papers), Virus-based gene therapy research (11 papers) and PI3K/AKT/mTOR signaling in cancer (7 papers). Alex G. Papageorge is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (15 papers), Virus-based gene therapy research (11 papers) and PI3K/AKT/mTOR signaling in cancer (7 papers). Alex G. Papageorge collaborates with scholars based in United States, Denmark and Malaysia. Alex G. Papageorge's co-authors include Douglas R. Lowy, Edward M. Scolnick, William C. Vass, Berthe M. Willumsen, N L Hubbert, Thomas Y. Shih, Clifford J. Tabin, Cornelia I. Bargmann, Scott M. Bradley and Robert A. Weinberg and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Alex G. Papageorge

52 papers receiving 5.0k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mechanism of activation of a human oncogene

1982 1.1k citations Alex G. Papageorge, Edward M. Scolnick et al. Nature profile →
The p21 ras C-terminus is required for transformation and membrane association

1984 501 citations Berthe M. Willumsen, Alex G. Papageorge et al. Nature profile →
Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

1992 482 citations Alex G. Papageorge, William C. Vass et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Alex G. Papageorge United States	33	4.1k	1.4k	974	836	580	53	5.4k
Dennis W. Stacey United States	39	4.5k 1.1×	1.8k 1.3×	908 0.9×	705 0.8×	514 0.9×	96	5.9k
David F. Barker United States	33	2.7k 0.7×	1.3k 0.9×	712 0.7×	1.4k 1.7×	703 1.2×	77	6.5k
Alessandra Eva Italy	35	3.5k 0.9×	1.0k 0.7×	1.1k 1.1×	579 0.7×	744 1.3×	111	5.5k
Jill M. Lahti United States	46	4.3k 1.1×	1.8k 1.3×	877 0.9×	481 0.6×	926 1.6×	88	5.9k
Nobuo Nomura Japan	31	3.4k 0.8×	1.2k 0.8×	871 0.9×	619 0.7×	270 0.5×	70	4.7k
John P. McGrath United States	22	4.5k 1.1×	2.3k 1.6×	681 0.7×	907 1.1×	411 0.7×	41	6.3k
Berthe M. Willumsen Denmark	28	4.2k 1.0×	1.4k 1.0×	1.0k 1.1×	355 0.4×	446 0.8×	47	5.1k
Anna T. Riegel United States	35	3.0k 0.7×	1.4k 1.0×	826 0.8×	1.3k 1.6×	771 1.3×	110	4.8k
Elizabeth M. Blackwood United States	18	3.9k 1.0×	1.2k 0.9×	429 0.4×	507 0.6×	620 1.1×	25	4.8k
Roseline Godbout Canada	44	4.9k 1.2×	1.7k 1.2×	439 0.5×	1.1k 1.4×	1.5k 2.5×	132	6.9k

Countries citing papers authored by Alex G. Papageorge

Since Specialization

Citations

This map shows the geographic impact of Alex G. Papageorge's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alex G. Papageorge with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alex G. Papageorge more than expected).

Fields of papers citing papers by Alex G. Papageorge

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alex G. Papageorge. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alex G. Papageorge. The network helps show where Alex G. Papageorge may publish in the future.

Co-authorship network of co-authors of Alex G. Papageorge

This figure shows the co-authorship network connecting the top 25 collaborators of Alex G. Papageorge. A scholar is included among the top collaborators of Alex G. Papageorge based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alex G. Papageorge. Alex G. Papageorge is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Tripathi, Brajendra K., Xiaolan Qian, Marian E. Durkin, et al.. (2024). The pro-oncogenic noncanonical activity of a RAS•GTP:RanGAP1 complex facilitates nuclear protein export. Nature Cancer. 5(12). 1902–1918. 1 indexed citations

Tripathi, Brajendra K., Xiaolan Qian, Dunrui Wang, et al.. (2021). Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein. Nature Communications. 12(1). 6941–6941. 12 indexed citations

Castel, Pau, Alice Cheng, Antonio Cuevas-Navarro, et al.. (2019). RIT1 oncoproteins escape LZTR1-mediated proteolysis. Science. 363(6432). 1226–1230. 57 indexed citations

Tripathi, Brajendra K., Xiaolan Qian, Ming Zhou, et al.. (2019). SRC and ERK cooperatively phosphorylate DLC1 and attenuate its Rho-GAP and tumor suppressor functions. The Journal of Cell Biology. 218(9). 3060–3076. 11 indexed citations

Tripathi, Brajendra K., Xiaolan Qian, Ming Zhou, et al.. (2017). Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1. The Journal of Cell Biology. 216(12). 4255–4270. 30 indexed citations

Du, Xiaoli, Xiaolan Qian, Alex G. Papageorge, et al.. (2012). Functional Interaction of Tumor Suppressor DLC1 and Caveolin-1 in Cancer Cells. Cancer Research. 72(17). 4405–4416. 42 indexed citations

Qian, Xiaolan, Guorong Li, William C. Vass, et al.. (2009). The Tensin-3 Protein, Including its SH2 Domain, Is Phosphorylated by Src and Contributes to Tumorigenesis and Metastasis. Cancer Cell. 16(3). 246–258. 75 indexed citations

Lowy, Douglas R., Jeffrey E. DeClue, Ke Zhang, et al.. (2007). Cell Transformation by ras and Regulation of its Protein Product. Novartis Foundation symposium. 176. 67–84. 1 indexed citations

Crawford, Nigel P.S., Xiaolan Qian, Argyrios Ziogas, et al.. (2007). Rrp1b, a New Candidate Susceptibility Gene for Breast Cancer Progression and Metastasis. PLoS Genetics. 3(11). e214–e214. 68 indexed citations

10.

Qian, Xiaolan, Luis Miguel Pedrero Esteban, William C. Vass, et al.. (2000). The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties. The EMBO Journal. 19(4). 642–654. 89 indexed citations

11.

Papageorge, Alex G., et al.. (1993). Regulated and Constitutive Activity by CDC25 ^Mm (GRF), a Ras-Specific Exchange Factor. Molecular and Cellular Biology. 13(12). 7718–7724. 45 indexed citations

12.

Cen, Han, et al.. (1992). Isolation of multiple mouse cDNAs with coding homology to Saccharomyces cerevisiae CDC25: identification of a region related to Bcr, Vav, Dbl and CDC24.. The EMBO Journal. 11(11). 4007–4015. 97 indexed citations

13.

Willumsen, Berthe M., William C. Vass, Thierry Velu, et al.. (1991). The Bovine Papillomavirus E5 Oncogene Can Cooperate with ras: Identification of p21 Amino Acids Critical for Transformation by c-ras ^H but Not v-ras ^H. Molecular and Cellular Biology. 11(12). 6026–6033. 19 indexed citations

14.

Zhang, Ke, Alex G. Papageorge, Patrick Martin, et al.. (1991). Heterogeneous Amino Acids in Ras and Rap1A Specifying Sensitivity to GAP Proteins. Science. 254(5038). 1630–1634. 32 indexed citations

15.

DeClue, Jeffrey E., James C. Stone, Alex G. Papageorge, et al.. (1991). A ras Effector Domain Mutant Which Is Temperature Sensitive for Cellular Transformation: Interactions with GTPase-Activating Protein and NF-1. Molecular and Cellular Biology. 11(6). 3132–3138. 28 indexed citations

16.

DeClue, Jeffrey E., et al.. (1991). A ras effector domain mutant which is temperature sensitive for cellular transformation: interactions with GTPase-activating protein and NF-1.. Molecular and Cellular Biology. 11(6). 3132–3138. 19 indexed citations

17.

Collin, Carlos, et al.. (1990). Early regulation of membrane excitability by ras oncogene proteins. Biophysical Journal. 58(3). 785–790. 13 indexed citations

18.

Zhang, Ke, Jeffrey E. DeClue, William C. Vass, et al.. (1990). Suppression of c-ras transformation by GTPase-activating protein. Nature. 346(6286). 754–756. 141 indexed citations

19.

Willumsen, Berthe M., Alex G. Papageorge, H F Kung, et al.. (1986). Mutational analysis of a ras catalytic domain.. Molecular and Cellular Biology. 6(7). 2646–2654. 180 indexed citations

20.

Papageorge, Alex G., et al.. (1984). Saccharomyces cerevisiae Synthesizes Proteins Related to the p21 Gene Product of ras Genes Found in Mammals. Molecular and Cellular Biology. 4(1). 23–29. 13 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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