Simon Messing

1.8k citations

27 papers · 814 indexed · h-index 15

Molecular Biology
- Protein Kinase Regulation and GTPase Signaling 9
- Protein Tyrosine Phosphatases 3
- PI3K/AKT/mTOR signaling in cancer 3
- Receptor Mechanisms and Signaling 3
- RNA and protein synthesis mechanisms 3
Biochemistry top 10%
Cell Biology
Plant Science
Infectious Diseases
- SARS-CoV-2 and COVID-19 Research 2
Materials Chemistry
- Enzyme Structure and Function 4
Oncology
- Peptidase Inhibition and Analysis 3

Co-authors: Dominic Esposito Frank McCormick Dwight V. Nissley Andrew G. Stephen L. Mario Amzel Sandra B. Gabelli Dhirendra K. Simanshu Troy Taylor
Cited by: Molecular Biology Biochemistry Cell Biology
Journals: Protein Expression and Purification (5 papers)Nature Communications (3 papers)Journal of Biological Chemistry (3 papers)
Partner nations: United States South Korea Canada

In The Last Decade

Simon Messing

26 papers receiving 809 citations

Peers

Countries citing papers authored by Simon Messing

Since Specialization

Citations

This map shows the geographic impact of Simon Messing's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon Messing with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon Messing more than expected).

Fields of papers citing papers by Simon Messing

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon Messing. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon Messing. The network helps show where Simon Messing may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Simon Messing, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Simon Messing Line = papers co-authored together Simon Messing links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Structural insights into isoform-specific RAS-PI3Kα interactions and the role of RAS in PI3Kα activation Nature Communications ·성건석,William Cross Crosse,Simon Messing,Э. Сафаров,Takashi Tsuji,Mitsuhiro Yamaguchi,Jan Schwartz,Spina Julieta,Dominic Esposito,Dwight V. Nissley,Frank McCormick,Dhirendra K. Simanshu	2025	8
2	Improved production of class I phosphatidylinositol 4,5-bisphosphate 3-kinase Protein Expression and Purification ·Simon Messing,N. I. Itinskaya,John-Paul Denson,Jennifer Mehalko,Vanessa Wall,Matthew Drew,Kelly Snead,Min Jee Hong,Jr. Otis Brown,Dominic Esposito,William Gillette	2024	1
3	A Top-Down Proteomic Assay to Evaluate KRAS4B-Compound Engagement Analytical Chemistry ·Sun Kyoung Un,Yanhui Li,Koto Shoji,Itul Anca,Matthew Drew,Claire Josey,Yalabik Muhendislik,N. I. Itinskaya,貞治熊谷,Simon Messing,David P. Turner,Michelle R. Arkin,Anna Maciąg,Andrew G. Stephen,Dominic Esposito,Frank McCormick,Dwight V. Nissley,Caroline J. DeHart	2024	5
4	Improvements in large-scale production of tobacco etch virus protease Protein Expression and Purification ·Simon Messing,Cheolwoong Kim,Matthew Drew,T. M. R. SCHOEDER,Jr. Otis Brown,Victor Mascarenhas,Min Jee Hong,Jeffrey S. Hull,Clémance Dellaire,Anna Szmytkowska,Claire Josey,Bo Pieter Johannes Andrée,Troy Taylor,Vanessa Wall,Nicholas J. Wright,Э. Сафаров,Dominic Esposito	2024	0
5	Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties Science Advances ·Matthew J. Whitley,Timothy H. Tran,Sohair T. Hamed,Ming Yi,Srisathiyanarayanan Dharmaiah,Timothy J. Waybright,Claire Josey,Clémance Dellaire,Troy Taylor,Simon Messing,Dominic Esposito,Dwight V. Nissley,Frank McCormick,Andrew G. Stephen,Thomas J. Turbyville,Gabriel Cornilescu,Dhirendra K. Simanshu	2024	14
6	Adapting recombinant bacterial alkaline phosphatase for nucleotide exchange of small GTPases Protein Expression and Purification ·Peter Frank,Min Jee Hong,Victor Mascarenhas,Clémance Dellaire,Troy Taylor,Vanessa Wall,Matthew Drew,Timothy J. Waybright,William Gillette,Dominic Esposito,Simon Messing	2024	2
7	RAS-dependent RAF-MAPK hyperactivation by pathogenic RIT1 is a therapeutic target in Noonan syndrome–associated cardiac hypertrophy Science Advances ·Antonio Cuevas-Navarro,Juan Pablo Afanador,Kendry Socovoski,Monalisa Swain,Gülzade Uysal,John Columbus,徐绍史,Alice Cheng,Simon Messing,Thomas J. Turbyville,Dhirendra K. Simanshu,Matthew J. Sale,Frank McCormick,Andrew G. Stephen,Pau Castel	2023	12
8	Structure of the SHOC2–MRAS–PP1C complex provides insights into RAF activation and Noonan syndrome Nature Structural & Molecular Biology ·Daniel A. Bonsor,Patrick Alexander,Kelly Snead,Nicole Hartig,Matthew Drew,Simon Messing,Lorenzo I. Finci,Dwight V. Nissley,Frank McCormick,Dominic Esposito,Pablo Rodriguez‐Viciana,Andrew G. Stephen,Dhirendra K. Simanshu	2022	27
9	Insights into the Cross Talk between Effector and Allosteric Lobes of KRAS from Methyl Conformational Dynamics Journal of the American Chemical Society ·Fa-An Chao,Srisathiyanarayanan Dharmaiah,Troy Taylor,Simon Messing,William Gillette,Dominic Esposito,Dwight V. Nissley,Frank McCormick,R. Andrew Byrd,Dhirendra K. Simanshu,Gabriel Cornilescu	2022	17
10	KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation Nature Communications ·Timothy H. Tran,Albert H. Chan,Lucy C. Young,Lakshman Bindu,Chris Neale,Simon Messing,Srisathiyanarayanan Dharmaiah,Troy Taylor,John-Paul Denson,Dominic Esposito,Dwight V. Nissley,Andrew G. Stephen,Frank McCormick,Dhirendra K. Simanshu	2021	139
11	Production and Membrane Binding of N-Terminally Acetylated, C-Terminally Farnesylated and Carboxymethylated KRAS4b Methods in molecular biology ·Simon Messing,Constance Agamasu,H.J.M. Zegers,Caroline J. DeHart,Andrew G. Stephen,William Gillette	2021	3
12	RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity Proceedings of the National Academy of Sciences ·Pau Castel,Srisathiyanarayanan Dharmaiah,Matthew J. Sale,Simon Messing,Gabrielle Rizzuto,Antonio Cuevas-Navarro,Alice Cheng,Michael J. Trnka,Anatoly Urisman,Dominic Esposito,Dhirendra K. Simanshu,Frank McCormick	2021	26
13	Fully Processed Recombinant KRAS4b: Isolating and Characterizing the Farnesylated and Methylated Protein Journal of Visualized Experiments ·Constance Agamasu,Peter Frank,Clémance Dellaire,Timothy J. Waybright,Simon Messing,William Gillette,Andrew G. Stephen	2020	1
14	Optimizing high-yield production of SARS-CoV-2 soluble spike trimers for serology assays Protein Expression and Purification ·Dominic Esposito,Jennifer Mehalko,Matthew Drew,Kelly Snead,Vanessa Wall,Troy Taylor,Peter Frank,K V Milyaev,Min Jee Hong,Gülçin Gülten,Kaitlyn Sadtler,Simon Messing,William Gillette	2020	52
15	Improved production of SARS-CoV-2 spike receptor-binding domain (RBD) for serology assays Protein Expression and Purification ·Jennifer Mehalko,Matthew Drew,Kelly Snead,John-Paul Denson,Vanessa Wall,Troy Taylor,Kaitlyn Sadtler,Simon Messing,William Gillette,Dominic Esposito	2020	19
16	Anionic Lipids Impact RAS-Binding Site Accessibility and Membrane Binding Affinity of CRAF RBD-CRD Biophysical Journal ·Timothy Travers,César A. López,Constance Agamasu,Jeevapani J. Hettige,Simon Messing,Angel E. Garcı́a,Andrew G. Stephen,S. Gnanakaran	2020	11
17	Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer Journal of Biological Chemistry ·正範中山,Sae‐Won Han,Rodolfo Ghirlando,Simon Messing,Matthew Drew,Yanhui Li,Timothy J. Waybright,Puneet Juneja,Hugh O’Neill,Christopher B. Stanley,Debsindhu Bhowmik,Arvind Ramanathan,Sriram Subramaniam,Dwight V. Nissley,William Gillette,Frank McCormick,Dominic Esposito	2019	32
18	Quantitative biophysical analysis defines key components modulating recruitment of the GTPase KRAS to the plasma membrane Journal of Biological Chemistry ·G. I. Sivak,Simon Messing,Eva M. Schmid,Jeffrey D. Clogston,William Gillette,Dominic Esposito,Bailey Kessing,Daniel A. Fletcher,Dwight V. Nissley,Frank McCormick,Andrew G. Stephen,Frantz Jean-François	2018	31
19	A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes Nature Communications ·Ivana Grabundžija,Simon Messing,Jainy Thomas,Rachel Cosby,Ilija Bilić,Csaba Miskey,Andreas Gogol‐Döring,Vladimir V. Kapitonov,Masaya Seki,J Rotman,Jerzy Jurka,Ellen J. Pritham,Fred Dyda,Zsuzsanna Izsvák,Zoltán Ivics	2016	82
20	The processing of repetitive extragenic palindromes: the structure of a repetitive extragenic palindrome bound to its associated nuclease Nucleic Acids Research ·Simon Messing,Bao Ton‐Hoang,Alison B. Hickman,Andrew J. McCubbin,G. F. Peaslee,Rodolfo Ghirlando,Michaël Chandler,Fred Dyda	2012	29

About Simon Messing

Simon Messing is a scholar working on Cell Biology, Molecular Biology and Oncology, having authored 27 papers that have together received 814 indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (9 papers), Enzyme Structure and Function (4 papers), Protein Tyrosine Phosphatases (3 papers), PI3K/AKT/mTOR signaling in cancer (3 papers), Peptidase Inhibition and Analysis (3 papers), Receptor Mechanisms and Signaling (3 papers), RNA and protein synthesis mechanisms (3 papers) and SARS-CoV-2 and COVID-19 Research (2 papers). The work is most often cited by research in Molecular Biology (634 citations), Biochemistry (44 citations) and Cell Biology (106 citations). Simon Messing has collaborated with scholars based in United States, South Korea and Canada. Frequent co-authors include Dominic Esposito, Frank McCormick, Dwight V. Nissley, Andrew G. Stephen, L. Mario Amzel, Sandra B. Gabelli, Dhirendra K. Simanshu, Troy Taylor, Srisathiyanarayanan Dharmaiah and Timothy H. Tran. Their work appears in journals such as Protein Expression and Purification, Nature Communications, Journal of Biological Chemistry, Science Advances and Biophysical Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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