Joseph B. Santella

1.8k total citations · 1 hit paper
19 papers, 901 citations indexed

About

Joseph B. Santella is a scholar working on Organic Chemistry, Molecular Biology and Oncology. According to data from OpenAlex, Joseph B. Santella has authored 19 papers receiving a total of 901 indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Organic Chemistry, 8 papers in Molecular Biology and 7 papers in Oncology. Recurrent topics in Joseph B. Santella's work include Chemical Synthesis and Analysis (5 papers), Chemokine receptors and signaling (5 papers) and Synthesis of Tetrazole Derivatives (4 papers). Joseph B. Santella is often cited by papers focused on Chemical Synthesis and Analysis (5 papers), Chemokine receptors and signaling (5 papers) and Synthesis of Tetrazole Derivatives (4 papers). Joseph B. Santella collaborates with scholars based in United States, Germany and Sweden. Joseph B. Santella's co-authors include John V. Duncia, Michael E. Pierce, David J. Carini, Andrew T. Chiu, A.L. Johnson, William A. Price, Gregory J. Wells, Paul E. Aldrich, John Hynes and Lyndon A. M. Cornelius and has published in prestigious journals such as Journal of Medicinal Chemistry, The Journal of Organic Chemistry and European Journal of Pharmacology.

In The Last Decade

Joseph B. Santella

19 papers receiving 850 citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives

1991 369 citations David J. Carini, John V. Duncia et al. Journal of Medicinal Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Joseph B. Santella United States	11	567	312	92	88	86	19	901
Ila Sircar United States	17	809 1.4×	432 1.4×	87 0.9×	86 1.0×	30 0.3×	33	1.1k
Elena Carceller Spain	18	374 0.7×	283 0.9×	27 0.3×	53 0.6×	55 0.6×	42	828
John S. Major United Kingdom	13	163 0.3×	282 0.9×	84 0.9×	42 0.5×	33 0.4×	27	578
Steven A. Boyd United States	18	320 0.6×	322 1.0×	71 0.8×	45 0.5×	18 0.2×	34	739
Herman H. Stein United States	20	548 1.0×	652 2.1×	264 2.9×	105 1.2×	25 0.3×	59	1.3k
Robert T. Lum United States	16	329 0.6×	332 1.1×	37 0.4×	135 1.5×	20 0.2×	19	759
Arvind Mathur United States	18	657 1.2×	243 0.8×	19 0.2×	75 0.9×	58 0.7×	87	983
Roger P. Dickinson United Kingdom	15	266 0.5×	215 0.7×	83 0.9×	65 0.7×	16 0.2×	26	636
Dennis Colussi United States	20	236 0.4×	328 1.1×	124 1.3×	64 0.7×	20 0.2×	44	827
Vı́ctor Segarra Spain	16	500 0.9×	385 1.2×	14 0.2×	62 0.7×	42 0.5×	41	899

Countries citing papers authored by Joseph B. Santella

Since Specialization

Citations

This map shows the geographic impact of Joseph B. Santella's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Joseph B. Santella with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Joseph B. Santella more than expected).

Fields of papers citing papers by Joseph B. Santella

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Joseph B. Santella. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Joseph B. Santella. The network helps show where Joseph B. Santella may publish in the future.

Co-authorship network of co-authors of Joseph B. Santella

This figure shows the co-authorship network connecting the top 25 collaborators of Joseph B. Santella. A scholar is included among the top collaborators of Joseph B. Santella based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Joseph B. Santella. Joseph B. Santella is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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19 of 19 papers shown

Ruepp, Stefan, Evan B. Janovitz, Joseph B. Santella, et al.. (2018). Assessing the risk of drug crystallization in vivo. Journal of Pharmacological and Toxicological Methods. 96. 1–8. 2 indexed citations

Carter, Percy H., Robert J. Cherney, Douglas G. Batt, et al.. (2015). Discovery of a Potent and Orally Bioavailable Dual Antagonist of CC Chemokine Receptors 2 and 5. ACS Medicinal Chemistry Letters. 6(4). 439–444. 11 indexed citations

Yang, Michael G., Zili Xiao, Qing Shi, et al.. (2011). Synthesis of 3-phenylsulfonylmethyl cyclohexylaminobenzamide-derived antagonists of CC chemokine receptor 2 (CCR2). Bioorganic & Medicinal Chemistry Letters. 22(3). 1384–1387. 2 indexed citations

Cherney, Robert J., Ruowei Mo, Dayton T. Meyer, et al.. (2010). γ-Lactams as glycinamide replacements in cyclohexane-based CC chemokine receptor 2 (CCR2) antagonists. Bioorganic & Medicinal Chemistry Letters. 20(8). 2425–2430. 15 indexed citations

D’Arienzo, Celia, Qin Ji, Lorell Discenza, et al.. (2010). DBS Sampling Can be Used to Stabilize Prodrugs in Drug Discovery Rodent Studies without the Addition of Esterase Inhibitors. Bioanalysis. 2(8). 1415–1422. 60 indexed citations

Gardner, Daniel S., Joseph B. Santella, Andrew J. Tebben, et al.. (2007). From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part II: Acyclic replacements for the (3S)-3-benzylpiperidine in a series of potent CCR3 antagonists. Bioorganic & Medicinal Chemistry Letters. 18(2). 586–595. 9 indexed citations

Batt, Douglas G., John Roderick, Joseph B. Santella, et al.. (2004). N-Arylalkylpiperidine urea derivatives as CC chemokine receptor-3 (CCR3) antagonists. Bioorganic & Medicinal Chemistry Letters. 15(3). 787–791. 12 indexed citations

Wityak, John, Frank W. Hobbs, Daniel S. Gardner, et al.. (2004). Beyond U0126. Dianion chemistry leading to the rapid synthesis of a series of potent MEK inhibitors. Bioorganic & Medicinal Chemistry Letters. 14(6). 1483–1486. 24 indexed citations

Varnes, Jeffrey, Daniel S. Gardner, Joseph B. Santella, et al.. (2004). Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonists. Bioorganic & Medicinal Chemistry Letters. 14(7). 1645–1649. 21 indexed citations

10.

Wacker, Dean A., Joseph B. Santella, Daniel S. Gardner, et al.. (2002). CCR3 antagonists: a potential new therapy for the treatment of asthma. Discovery and structure–activity relationships. Bioorganic & Medicinal Chemistry Letters. 12(13). 1785–1789. 35 indexed citations

11.

Duncia, John V., Joseph B. Santella, C. Anne Higley, et al.. (1998). Pyrazoles, 1,2,4-triazoles, and tetrazoles as surrogates for cis-amide bonds in boronate ester thrombin inhibitors. Bioorganic & Medicinal Chemistry Letters. 8(7). 775–780. 32 indexed citations

12.

Quan, Mimi L., John Wityak, Celia Dominguez, et al.. (1997). Biaryl substituted alkylboronate esters as thrombin inhibitors. Bioorganic & Medicinal Chemistry Letters. 7(13). 1595–1600. 8 indexed citations

13.

Duncia, John V., Joseph B. Santella, Andrew T. Chiu, Pancras C. Wong, & Ruth R. Wexler. (1995). Dibenzobicyclo[2.2.2.]octane angiotensin II receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 5(3). 241–246. 2 indexed citations

14.

Santella, Joseph B., John V. Duncia, Carol L. Ensinger, et al.. (1994). Balanced angiotensin II receptor antagonists. III. The effects of substitution at the imidazole 5-position.. Bioorganic & Medicinal Chemistry Letters. 4(18). 2235–2240. 14 indexed citations

15.

Wong, Pancras C., John V. Duncia, Joseph B. Santella, et al.. (1994). EXP597, a nonpeptide angiotensin II receptor antagonist with high affinities for the angiotensin AT1 and AT2 receptor subtypes. European Journal of Pharmacology. 260(2-3). 261–264. 3 indexed citations

16.

Duncia, John V., Michael E. Pierce, & Joseph B. Santella. (1991). ChemInform Abstract: Three Synthetic Route to a Sterically Hindered Tetrazole. A New One‐Step Mild Conversion of an Amide into a Tetrazole.. ChemInform. 22(34). 7 indexed citations

17.

Duncia, John V., Michael E. Pierce, & Joseph B. Santella. (1991). Three synthetic routes to a sterically hindered tetrazole. A new one-step mild conversion of an amide into a tetrazole. The Journal of Organic Chemistry. 56(7). 2395–2400. 274 indexed citations

18.

Carini, David J., John V. Duncia, Paul E. Aldrich, et al.. (1991). ChemInform Abstract: Nonpeptide Angiotensin II Receptor Antagonists: The Discovery of a Series of N‐(Biphenylylmethyl)imidazoles as Potent, Orally Active Antihypertensives.. ChemInform. 22(52). 1 indexed citations

19.

Carini, David J., John V. Duncia, Paul E. Aldrich, et al.. (1991). Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives. Journal of Medicinal Chemistry. 34(8). 2525–2547. 369 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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