Joseph B. Santella

1.8k citations

19 papers · 901 indexed · 1 hit paper · h-index 11

Co-authors: John V. Duncia Michael E. Pierce Andrew T. Chiu David J. Carini William A. Price Paul E. Aldrich A.L. Johnson Gregory J. Wells
Topics: Chemical Synthesis and Analysis (5 papers)Chemokine receptors and signaling (5 papers)Synthesis of Tetrazole Derivatives (4 papers)
Cited by: Organic Chemistry Computational Theory and Mathematics Molecular Biology
Journals: Journal of Medicinal Chemistry The Journal of Organic Chemistry European Journal of Pharmacology
Partner nations: United States Germany Sweden

In The Last Decade

Joseph B. Santella

19 papers receiving 850 citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives

1991 369 citations David J. Carini, John V. Duncia et al. Journal of Medicinal Chemistry profile →

Peers

Countries citing papers authored by Joseph B. Santella

Since Specialization

Citations

This map shows the geographic impact of Joseph B. Santella's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Joseph B. Santella with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Joseph B. Santella more than expected).

Fields of papers citing papers by Joseph B. Santella

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Joseph B. Santella. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Joseph B. Santella. The network helps show where Joseph B. Santella may publish in the future.

Co-authorship network of co-authors of Joseph B. Santella

This figure shows the co-authorship network connecting the top 25 collaborators of Joseph B. Santella. A scholar is included among the top collaborators of Joseph B. Santella based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Joseph B. Santella. Joseph B. Santella is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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19 of 19 papers shown

#	Work	Indexed citations
1	Assessing the risk of drug crystallization in vivo 2018 ·Journal of Pharmacological and Toxicological Methods ·Stefan Ruepp,Evan B. Janovitz,(unknown),(unknown),Joseph B. Santella,John Hynes,Julie Carman,Duohai Pan,Wu Yang,Umesh Hanumegowda,Brian Gemzik,John R. Megill,(unknown),Dieter M. Drexler,(unknown),Michael J. Hageman	2
2	Discovery of a Potent and Orally Bioavailable Dual Antagonist of CC Chemokine Receptors 2 and 5 2015 ·ACS Medicinal Chemistry Letters ·Percy H. Carter,(unknown),Robert J. Cherney,Douglas G. Batt,Jing Chen,(unknown),Mary Ellen Cvijic,John V. Duncia,Soo S. Ko,Sandhya Mandlekar,Ruowei Mo,David J. Nelson,Jian Pang,Anne Rose,Joseph B. Santella,Andrew J. Tebben,Sarah C. Traeger,(unknown),Qihong Zhao,Joel C. Barrish	11
3	Synthesis of 3-phenylsulfonylmethyl cyclohexylaminobenzamide-derived antagonists of CC chemokine receptor 2 (CCR2) 2011 ·Bioorganic & Medicinal Chemistry Letters ·Michael G. Yang,Zili Xiao,Qing Shi,Robert J. Cherney,Andrew J. Tebben,George V. De Lucca,Joseph B. Santella,Ruowei Mo,Mary Ellen Cvijic,Qihong Zhao,Joel C. Barrish,Percy H. Carter	2
4	γ-Lactams as glycinamide replacements in cyclohexane-based CC chemokine receptor 2 (CCR2) antagonists 2010 ·Bioorganic & Medicinal Chemistry Letters ·Robert J. Cherney,Ruowei Mo,Dayton T. Meyer,Matthew E. Voss,Michael G. Yang,Joseph B. Santella,John V. Duncia,(unknown),Gengjie Yang,(unknown),Peggy Scherle,Qihong Zhao,Sandhya Mandlekar,Mary Ellen Cvijic,Joel C. Barrish,Carl P. Decicco,Percy H. Carter	15
5	DBS Sampling Can be Used to Stabilize Prodrugs in Drug Discovery Rodent Studies without the Addition of Esterase Inhibitors 2010 ·Bioanalysis ·Celia D’Arienzo,Qin Ji,Lorell Discenza,Georgia Cornelius,John Hynes,Lyndon A. M. Cornelius,Joseph B. Santella,Timothy Olah	60
6	From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part II: Acyclic replacements for the (3S)-3-benzylpiperidine in a series of potent CCR3 antagonists 2007 ·Bioorganic & Medicinal Chemistry Letters ·Daniel S. Gardner,Joseph B. Santella,Andrew J. Tebben,Douglas G. Batt,Soo S. Ko,Sarah C. Traeger,(unknown),Eric Wadman,Paul Davies,Percy H. Carter,John V. Duncia	9
7	N-Arylalkylpiperidine urea derivatives as CC chemokine receptor-3 (CCR3) antagonists 2004 ·Bioorganic & Medicinal Chemistry Letters ·Douglas G. Batt,(unknown),John Roderick,Joseph B. Santella,Dean A. Wacker,(unknown),(unknown),Eric Wadman,James M. Trzăskos,Paul Davies,Carl P. Decicco,Percy H. Carter	12
8	Beyond U0126. Dianion chemistry leading to the rapid synthesis of a series of potent MEK inhibitors 2004 ·Bioorganic & Medicinal Chemistry Letters ·John Wityak,Frank W. Hobbs,Daniel S. Gardner,Joseph B. Santella,Joseph J. Petraitis,Jung‐Hui Sun,Margaret Favata,(unknown),Kurumi Y. Horiuchi,Robert A. Copeland,Peggy Scherle,(unknown),James M. Trzăskos,Ronald L. Magolda,George L. Trainor,John V. Duncia	24
9	Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonists 2004 ·Bioorganic & Medicinal Chemistry Letters ·Jeffrey Varnes,Daniel S. Gardner,Joseph B. Santella,John V. Duncia,(unknown),Paul S. Watson,(unknown),Soo S. Ko,(unknown),Maryanne Covington,Nicole Stowell,Eric Wadman,Paul Davies,(unknown),Robert Newton,George L. Trainor,Carl P. Decicco,Dean A. Wacker	21
10	CCR3 antagonists: a potential new therapy for the treatment of asthma. Discovery and structure–activity relationships 2002 ·Bioorganic & Medicinal Chemistry Letters ·Dean A. Wacker,Joseph B. Santella,Daniel S. Gardner,Jeffrey Varnes,(unknown),(unknown),Soo S. Ko,(unknown),Paul S. Watson,(unknown),Maryanne Covington,Nicole Stowell,Eric Wadman,Paul Davies,Kimberly A. Solomon,Robert Newton,George L. Trainor,Steven Friedman,Carl P. Decicco,John V. Duncia	35
11	Pyrazoles, 1,2,4-triazoles, and tetrazoles as surrogates for cis-amide bonds in boronate ester thrombin inhibitors 1998 ·Bioorganic & Medicinal Chemistry Letters ·John V. Duncia,Joseph B. Santella,C. Anne Higley,(unknown),Patricia C Weber,Richard Alexander,Charles A. Kettner,James R. Pruitt,(unknown),Mimi L. Quan,Robert M. Knabb,Ruth R. Wexler	32
12	Biaryl substituted alkylboronate esters as thrombin inhibitors 1997 ·Bioorganic & Medicinal Chemistry Letters ·Mimi L. Quan,John Wityak,Celia Dominguez,John V. Duncia,Charles A. Kettner,Christopher D. Ellis,Ann Y. Liauw,(unknown),Joseph B. Santella,Robert M. Knabb,Martin Thoolen,P.C. Weber,Ruth R. Wexler	8
13	Dibenzobicyclo[2.2.2.]octane angiotensin II receptor antagonists 1995 ·Bioorganic & Medicinal Chemistry Letters ·John V. Duncia,Joseph B. Santella,Andrew T. Chiu,Pancras C. Wong,Ruth R. Wexler	2
14	Balanced angiotensin II receptor antagonists. III. The effects of substitution at the imidazole 5-position. 1994 ·Bioorganic & Medicinal Chemistry Letters ·Joseph B. Santella,John V. Duncia,Carol L. Ensinger,(unknown),David J. Carini,Ruth R. Wexler,Andrew T. Chiu,Pancras C. Wong,Pieter B.M.W.M. Timmermans	14
15	EXP597, a nonpeptide angiotensin II receptor antagonist with high affinities for the angiotensin AT1 and AT2 receptor subtypes 1994 ·European Journal of Pharmacology ·Pancras C. Wong,John V. Duncia,Joseph B. Santella,Ronald D. Smith,Ruth R. Wexler,Pieter B.M.W.M. Timmermans,Andrew T. Chiu	3
16	Three synthetic routes to a sterically hindered tetrazole. A new one-step mild conversion of an amide into a tetrazole 1991 ·The Journal of Organic Chemistry ·John V. Duncia,Michael E. Pierce,Joseph B. Santella	274
17	ChemInform Abstract: Three Synthetic Route to a Sterically Hindered Tetrazole. A New One‐Step Mild Conversion of an Amide into a Tetrazole. 1991 ·ChemInform ·John V. Duncia,Michael E. Pierce,Joseph B. Santella	7
18	ChemInform Abstract: Nonpeptide Angiotensin II Receptor Antagonists: The Discovery of a Series of N‐(Biphenylylmethyl)imidazoles as Potent, Orally Active Antihypertensives. 1991 ·ChemInform ·David J. Carini,John V. Duncia,Paul E. Aldrich,Andrew T. Chiu,A.L. Johnson,Michael E. Pierce,William A. Price,Joseph B. Santella,Gregory J. Wells,Ruth R. Wexler,Pancras C. Wong,Sung‐Eun Yoo,Pieter B.M.W.M. Timmermans	1
19	Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensivesbreakdown → 1991 ·Journal of Medicinal Chemistry ·David J. Carini,John V. Duncia,Paul E. Aldrich,Andrew T. Chiu,A.L. Johnson,Michael E. Pierce,William A. Price,Joseph B. Santella,Gregory J. Wells	369

About Joseph B. Santella

Joseph B. Santella is a scholar working on Organic Chemistry, Microbiology and Oncology, having authored 19 papers that have together received 901 indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (5 papers), Chemokine receptors and signaling (5 papers) and Synthesis of Tetrazole Derivatives (4 papers). The work is most often cited by research in Organic Chemistry (567 citations), Computational Theory and Mathematics (75 citations) and Molecular Biology (312 citations). Joseph B. Santella has collaborated with scholars based in United States, Germany and Sweden. Frequent co-authors include John V. Duncia, Michael E. Pierce, Andrew T. Chiu, David J. Carini, William A. Price, Paul E. Aldrich, A.L. Johnson, Gregory J. Wells, Georgia Cornelius and Lorell Discenza. Their work appears in journals such as Journal of Medicinal Chemistry, The Journal of Organic Chemistry and European Journal of Pharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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