David W. Melton

9.1k citations

106 papers · 6.3k indexed · 2 hit papers · h-index 45

Co-authors: Jim Selfridge C. Thomas Caskey Martin Hooper Jim McWhir Simon Thompson Thomas M. Magin David Konecki John Brennand
Topics: DNA Repair Mechanisms (32 papers)CRISPR and Genetic Engineering (24 papers)Biochemical and Molecular Research (16 papers)
Cited by: Molecular Biology Genetics Cancer Research
Journals: Nature Cell Proceedings of the National Academy of Sciences
Partner nations: United Kingdom United States France

In The Last Decade

David W. Melton

104 papers receiving 6.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Targetted correction of a mutant HPRT gene in mouse embryonic stem cells

1987 550 citations Thomas Doetschman, Ronald G. Gregg et al. Nature profile →
Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene.

1984 396 citations David W. Melton et al. profile →

Peers

Countries citing papers authored by David W. Melton

Since Specialization

Citations

This map shows the geographic impact of David W. Melton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David W. Melton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David W. Melton more than expected).

Fields of papers citing papers by David W. Melton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David W. Melton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David W. Melton. The network helps show where David W. Melton may publish in the future.

Co-authorship network of co-authors of David W. Melton

This figure shows the co-authorship network connecting the top 25 collaborators of David W. Melton. A scholar is included among the top collaborators of David W. Melton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David W. Melton. David W. Melton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Demographic changes in COVID-19 mortality during the pandemic: analysis of trends in disparities among workers using California’s mortality surveillance system 2024 ·BMC Public Health ·(unknown),David Bui,Kristin J. Cummings,(unknown),Alyssa Nguyen,(unknown),David W. Melton,(unknown),Seema Jain,Ximena Vergara	0
2	CalScope: methodology and lessons learned for conducting a remote statewide SARS-CoV-2 seroprevalence study in California using an at-home dried blood spot collection kit and online survey 2024 ·BMC Medical Research Methodology ·Esther Lim,Megha Mehrotra,Katherine Lamba,Amanda Kamali,Kristina Lai,(unknown),(unknown),(unknown),Catherine Ley,Andrew Martin,Julie Parsonnet,Peter N. Robinson,(unknown),(unknown),Cheng‐ting Tsai,David Seftel,(unknown),David W. Melton,Seema Jain	2
3	Identifying and overcoming a mechanism of resistance to WEE1 kinase inhibitor AZD1775 in high grade serous ovarian cancer cells 2022 ·European Journal of Gynaecological Oncology ·(unknown),John P. Thomson,Graeme R. Grimes,Anderson T. Wang,Michael Churchman,Mark J. O’Connor,Charlie Gourley,David W. Melton	11
4	Extracellular mitochondria drive CD8 T cell dysfunction in trauma by upregulating CD39 2022 ·Thorax ·Shilpa Tiwari‐Heckler,(unknown),(unknown),Carola Ledderose,Eva Csizmadia,David W. Melton,Quan‐Zhi Zhang,Wolfgang G. Junger,Guanqing Chen,Carl J. Hauser,Leo E. Otterbein,Maria Serena Longhi,Simon C. Robson	7
5	Deriving a Boolean dynamics to reveal macrophage activation with in vitro temporal cytokine expression profiles 2019 ·BMC Bioinformatics ·Ricardo J. Ramirez,(unknown),(unknown),Chunjiang Qian,David W. Melton,Paula K. Shireman,Yu-Fang Jin	10
6	Inhibition of the ERCC1–XPF structure-specific endonuclease to overcome cancer chemoresistance 2015 ·DNA repair ·Ewan M. McNeil,Katy R. Astell,(unknown),Steven Shave,Douglas R. Houston,Preeti Bakrania,(unknown),(unknown),Claire Wallace,Tim Chapman,Martin A. Wear,Malcolm D. Walkinshaw,Barbara Saxty,David W. Melton	61
7	Increased Adipocyte Area in Injured Muscle With Aging and Impaired Remodeling in Female Mice 2015 ·The Journals of Gerontology Series A ·(unknown),David W. Melton,Xiufen Lei,(unknown),Hanzhou Wang,Zaheer Sarwar,(unknown),(unknown),Linda M. McManus,Paula K. Shireman	11
8	Temporal phenotypic features distinguish polarized macrophagesin vitro 2015 ·Autoimmunity ·David W. Melton,Linda M. McManus,Jonathan Gelfond,Paula K. Shireman	58
9	Fascin expression is increased in metastatic lesions but does not correlate with progression nor outcome in melanoma 2015 ·Melanoma Research ·Yafeng Ma,William J. Faller,Owen J. Sansom,Ewan Brown,(unknown),David W. Melton,Laura M. Machesky	11
10	ALDH2 Mediates 5-Nitrofuran Activity in Multiple Species 2012 ·Chemistry & Biology ·Linna Zhou,Hironori Ishizaki,Michaela Spitzer,Kerrie L. Taylor,Nicholas D. Temperley,Stephen L. Johnson,P. Brear,Philippe Gautier,Zhiqiang Zeng,(unknown),Vikram Narayan,Ewan M. McNeil,David W. Melton,Terry Smith,Mike Tyers,Nicholas J. Westwood,(unknown)	40
11	Maternal germline-specific effect of DNA ligase I on CTG/CAG instability 2011 ·Human Molecular Genetics ·Santiago Tomé,Gagan B. Panigrahi,Arturo López Castel,(unknown),David W. Melton,Geneviève Gourdon,Christopher E. Pearson	28
12	A novel transcript for DNA repair gene Ercc1 in mouse skin 2010 ·Transgenic Research ·Liang Song,Andrew Winter,Jim Selfridge,David W. Melton	3
13	Improved Coinfection with Amphotropic Pseudotyped Retroviral Vectors 2009 ·BioMed Research International ·Yuehong Wu,David W. Melton,Yong Zhang,Peter J. Hornsby	11
14	Characterisation of Ercc1 deficiency in the liver and in conditional Ercc1-deficient primary hepatocytes in vitro 2006 ·DNA repair ·Kristina Kirschner,Rajinder Singh,Sandrine Prost,David W. Melton	14
15	The formation of UV-induced chromosome aberrations involves ERCC1 and XPF but not other nucleotide excision repair genes 2002 ·DNA repair ·(unknown),David W. Melton	21
16	Changing a single amino acid in the N-terminus of murine PrP alters TSE incubation time across three species barriers 2001 ·The EMBO Journal ·Rona Barron,Val Thomson,Elizabeth R. Jamieson,David W. Melton,James W. Ironside,Robert Will,Jean Manson	94
17	Use of Double-Replacement Gene Targeting to Replace the Murine α-Lactalbumin Gene with Its Human Counterpart in Embryonic Stem Cells and Mice 1994 ·Molecular and Cellular Biology ·(unknown),Angelika Schnieke,Jim McWhir,(unknown),Alan Colman,David W. Melton	29
18	Analysis of Forebrain Dopaminergic Pathways in HPRT — Mice 1991 ·Advances in experimental medicine and biology ·Dominic J. Williamson,John Sharkey,Alan R. Clarke,Allan Jamieson,Gordon W. Arbuthnott,Paul A. Kelly,David W. Melton,M.L. Hooper	13
19	Abstracts of papers presented at the 14th Mammalian Molecular and Biochemical Genetics Workshop held in London on 10th and 11th November 1987 1988 ·Genetics Research ·Michail Antoniou,Elke de Boer,(unknown),David R. Greaves,F Grosveld,Asangla Ao,Marilyn Monk,Robin Lovell‐Badge,David W. Melton	1
20	Targetted correction of a mutant HPRT gene in mouse embryonic stem cellsbreakdown → 1987 ·Nature ·Thomas Doetschman,Ronald G. Gregg,Nobuyo Maeda,Martin Hooper,David W. Melton,Simon Thompson,Oliver Smithies	550

About David W. Melton

David W. Melton is a scholar working on Molecular Biology, Genetics and Cancer Research, having authored 106 papers that have together received 6.3k indexed citations. Recurring topics across this work include DNA Repair Mechanisms (32 papers), CRISPR and Genetic Engineering (24 papers) and Biochemical and Molecular Research (16 papers). The work is most often cited by research in Molecular Biology (5.1k citations), Genetics (1.4k citations) and Cancer Research (709 citations). David W. Melton has collaborated with scholars based in United Kingdom, United States and France. Frequent co-authors include Jim Selfridge, C. Thomas Caskey, Martin Hooper, Jim McWhir, Simon Thompson, Thomas M. Magin, David Konecki, John Brennand, Ewan M. McNeil and Alan R. Clarke. Their work appears in journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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