Alfonso Bellacosa

18.9k total citations · 9 hit papers
118 papers, 14.4k citations indexed

About

Alfonso Bellacosa is a scholar working on Molecular Biology, Oncology and Pathology and Forensic Medicine. According to data from OpenAlex, Alfonso Bellacosa has authored 118 papers receiving a total of 14.4k indexed citations (citations by other indexed papers that have themselves been cited), including 96 papers in Molecular Biology, 30 papers in Oncology and 29 papers in Pathology and Forensic Medicine. Recurrent topics in Alfonso Bellacosa's work include PI3K/AKT/mTOR signaling in cancer (24 papers), DNA Repair Mechanisms (20 papers) and Genetic factors in colorectal cancer (20 papers). Alfonso Bellacosa is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (24 papers), DNA Repair Mechanisms (20 papers) and Genetic factors in colorectal cancer (20 papers). Alfonso Bellacosa collaborates with scholars based in United States, Italy and France. Alfonso Bellacosa's co-authors include Joseph R. Testa, Philip N. Tsichlis, Lionel Larue, P N Tsichlis, Tung O. Chan, Stephen Staal, H. Leighton Grimes, C. Chandra Kumar, Antonio Di Cristofano and Nissim Hay and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Alfonso Bellacosa

116 papers receiving 14.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Epithelial–mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways

2005 983 citations Lionel Larue, Alfonso Bellacosa Oncogene profile →
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

1997 972 citations Alfonso Bellacosa et al. profile →
AKT plays a central role in tumorigenesis

2001 764 citations Joseph R. Testa, Alfonso Bellacosa profile →
A Retroviral Oncogene, akt , Encoding a Serine-Threonine Kinase Containing an SH2-Like Region

1991 720 citations Alfonso Bellacosa, Joseph R. Testa et al. profile →
Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas

1995 691 citations Alfonso Bellacosa, Andrew K. Godwin et al. International Journal of Cancer profile →
Activation of AKT Kinases in Cancer: Implications for Therapeutic Targeting

2005 664 citations Alfonso Bellacosa, Joseph R. Testa et al. profile →
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.

1992 582 citations Andrew K. Godwin, Alfonso Bellacosa et al. profile →
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27Kip1 by PKB/Akt-mediated phosphorylation in breast cancer

2002 562 citations Philip N. Tsichlis, Alfonso Bellacosa et al. profile →
The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines.

2003 537 citations Alfonso Bellacosa, John J. Upson et al. PubMed profile →

Peers

Countries citing papers authored by Alfonso Bellacosa

Since Specialization

Citations

This map shows the geographic impact of Alfonso Bellacosa's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alfonso Bellacosa with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alfonso Bellacosa more than expected).

Fields of papers citing papers by Alfonso Bellacosa

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alfonso Bellacosa. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alfonso Bellacosa. The network helps show where Alfonso Bellacosa may publish in the future.

Co-authorship network of co-authors of Alfonso Bellacosa

This figure shows the co-authorship network connecting the top 25 collaborators of Alfonso Bellacosa. A scholar is included among the top collaborators of Alfonso Bellacosa based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alfonso Bellacosa. Alfonso Bellacosa is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Alterations of the AKT Pathway in Sporadic Human Tumors, Inherited Susceptibility to Cancer, and Overgrowth Syndromes 2024 ·Current topics in microbiology and immunology ·Craig W. Menges, (unknown), Mitchell Cheung, Alfonso Bellacosa, Joseph R. Testa	1
2	MBD4 loss results in global reactivation of promoters and retroelements with low methylated CpG density 2023 ·Journal of Experimental & Clinical Cancer Research ·Christophe Papin, Abdulkhaleg Ibrahim, Jamal S. M. Sabir, Stéphanie Le Gras, Isabelle Stoll, Raed Albiheyri, (unknown), Ahmed Bahieldin, Alfonso Bellacosa, Christian Bronner, Ali Hamiche	3
3	The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells 2022 ·Science Signaling ·Alison Kurimchak, (unknown), Sara Montserrat‐Sangrà, Daniela Araiza‐Olivera, Jianping Hu, (unknown), Mathew Kuruvilla, Alfonso Bellacosa, Joseph R. Testa, Jian Jin, James S. Duncan	64
4	Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells 2021 ·Genome biology ·Atsushi Onodera, Edahí González‐Avalos, Chan‐Wang Jerry Lio, Romain O. Georges, Alfonso Bellacosa, Toshinori Nakayama, Anjana Rao	51
5	Alfred G. Knudson (1922–2016) 2016 ·Cell ·Alfonso Bellacosa, Jonathan Chernoff, Joseph R. Testa	0
6	Role of base excision repair in maintaining the genetic and epigenetic integrity of CpG sites 2015 ·DNA repair ·Alfonso Bellacosa, Alexander C. Drohat	71
7	Beta-catenin inhibits melanocyte migration but induces melanoma metastasis 2012 ·Oncogene ·Stuart Gallagher, Florian Rambow, Mayuko Y. Kumasaka, Delphine Champeval, Alfonso Bellacosa, Véronique Delmas, Lionel Larue	84
8	Altered Gene Expression in Morphologically Normal Epithelial Cells from Heterozygous Carriers of BRCA1 or BRCA2 Mutations 2010 ·Cancer Prevention Research ·Alfonso Bellacosa, Andrew K. Godwin, Suraj Peri, Karthik Devarajan, Elena Caretti, Lisa Vanderveer, Betsy Bove, Carolyn Slater, Yan Zhou, Mary B. Daly, (unknown), Kerry S. Campbell, Émmanuelle Nicolas, Anthony T. Yeung, Margie L. Clapper, James A. Crowell, Henry T. Lynch, Eric A. Ross, Levy Kopelovich, Alfred G. Knudson	41
9	One-Hit Effects in Cancer: Altered Proteome of Morphologically Normal Colon Crypts in Familial Adenomatous Polyposis 2008 ·Cancer Research ·Anthony T. Yeung, (unknown), Xinming Li, Steven H. Seeholzer, Renata A. Coudry, Harry S. Cooper, Alfonso Bellacosa, Bruce M. Boman, Tao Zhang, Samuel Litwin, Eric A. Ross, Peggy Conrad, James A. Crowell, Levy Kopelovich, Alfred G. Knudson	34
10	Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4 2008 ·Developmental Biology ·Salvatore Cortellino, Chengbing Wang, (unknown), Maria Rosaria Bassi, Elena Caretti, Delphine Champeval, Amélie Calmont, Michal Jarník, John B.E. Burch, Kenneth S. Zaret, Lionel Larue, Alfonso Bellacosa	97
11	Activation of NF-κB by Akt upregulates Snail expression and induces epithelium mesenchyme transition 2007 ·Oncogene ·Sylvia Julien, Isabel Puig, Elena Caretti, Jacky Bonaventure, L Nelles, Frans van Roy, Catherine Dargemont, Antonio Garcı́a de Herreros, Alfonso Bellacosa, Lionel Larue	399
12	Induction of Deoxyribonucleic Acid Damage by γ Irradiation 2004 ·Humana Press eBooks ·Salvatore Cortellino, David P. Turner, Alfonso Bellacosa	3
13	A Portrait of AKT Kinases: Human Cancer and Animal Models Depict a Family with Strong Individualities 2004 ·Cancer Biology & Therapy ·Alfonso Bellacosa, Joseph R. Testa, Robert J. Moore, Lionel Larue	105
14	The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. breakdown → 2003 ·PubMed ·(unknown), Alfonso Bellacosa, John J. Upson, Andres J. Klein–Szanto, Frans van Roy, Whaseon Lee‐Kwon, Mark Donowitz, Philip N. Tsichlis, Lionel Larue	537
15	RNA Repair: Damage Control 2003 ·Current Biology ·Alfonso Bellacosa, Eric G. Moss	66
16	Biphasic Kinetics of the Human DNA Repair Protein MED1 (MBD4), a Mismatch-specific DNA N-Glycosylase 2000 ·Journal of Biological Chemistry ·Fiorella Petronzelli, Antonio Riccio, George D. Markham, Steven H. Seeholzer, Jay Stoerker, Maurizio Genuardi, Anthony T. Yeung, Yoshihiro Matsumoto, Alfonso Bellacosa	139
17	Survival analysis in families affected by hereditary non-polyposis colorectal cancer 1997 ·International Journal of Cancer ·Antonio Percesepe, Piero Benatti, Luca Roncucci, Romano Sassatelli, Rossella Fante, D. Ganazzi, Alfonso Bellacosa, Maurizio Genuardi, Giovanni Neri, Alessandra Viel, Maurizio Ponz de Leòn	49
18	Prognostic significance of ras/p21 alterations in human ovarian cancer 1997 ·British Journal of Cancer ·Giovanni Scambia, Valeria Masciullo, P. Benedetti Panici, Maria Marone, Gabriella Ferrandina, (unknown), Alfonso Bellacosa, (unknown), Giovanni Neri, A Piffanelli, Stefano Mancuso	19
19	Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas breakdown → 1995 ·International Journal of Cancer ·Alfonso Bellacosa, (unknown), Andrew K. Godwin, Daphne W. Bell, Jin Q. Cheng, Deborah A. Altomare, Minghong Wan, Louis Dubeau, Giovanni Scambia, Valeria Masciullo, Gabriella Ferrandina, Pierluigi Benedetti Panici, Salvatore Mancuso, Giovanni Neri, Joseph R. Testa	691
20	The Rat Leukocyte Antigen MRC OX-44 Is a Member of a New Family of Cell Surface Proteins Which Appear To Be Involved in Growth Regulation 1991 ·Molecular and Cellular Biology ·Alfonso Bellacosa, Pedro A. Lazo, S E Bear, Philip N. Tsichlis	13

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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