Christiaan Klijn

4.6k total citations · 1 hit paper
30 papers, 1.8k citations indexed

About

Christiaan Klijn is a scholar working on Molecular Biology, Genetics and Cancer Research. According to data from OpenAlex, Christiaan Klijn has authored 30 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 23 papers in Molecular Biology, 11 papers in Genetics and 11 papers in Cancer Research. Recurrent topics in Christiaan Klijn's work include Cancer Genomics and Diagnostics (10 papers), DNA Repair Mechanisms (6 papers) and BRCA gene mutations in cancer (6 papers). Christiaan Klijn is often cited by papers focused on Cancer Genomics and Diagnostics (10 papers), DNA Repair Mechanisms (6 papers) and BRCA gene mutations in cancer (6 papers). Christiaan Klijn collaborates with scholars based in Netherlands, United Kingdom and France. Christiaan Klijn's co-authors include Jos Jonkers, Richard Bourgon, Lodewyk F.A. Wessels, Zora Modrušan, Hartmut Koeppen, Sören Müller, Melissa R. Junttila, Yasin Şenbabaoğlu, Shannon J. Turley and Sarah Gierke and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Christiaan Klijn

29 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy

2019 522 citations Claudia X. Dominguez, Sören Müller et al. Cancer Discovery profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Christiaan Klijn Netherlands	20	1.2k	813	407	342	239	30	1.8k
Andrey Khramtsov United States	18	983 0.8×	886 1.1×	494 1.2×	340 1.0×	222 0.9×	34	1.8k
Somaia Elsheikh United Kingdom	16	1.0k 0.8×	791 1.0×	636 1.6×	248 0.7×	182 0.8×	25	1.8k
Béatrice Orsetti France	26	953 0.8×	591 0.7×	483 1.2×	286 0.8×	108 0.5×	43	1.5k
Trevor G. Shepherd Canada	26	1.1k 0.9×	644 0.8×	406 1.0×	173 0.5×	157 0.7×	64	1.8k
Kienan I. Savage United Kingdom	20	1.6k 1.3×	739 0.9×	339 0.8×	243 0.7×	259 1.1×	44	2.1k
Simon S. McDade United Kingdom	24	992 0.8×	589 0.7×	362 0.9×	161 0.5×	181 0.8×	55	1.6k
Deborah A. Zajchowski United States	26	1.3k 1.0×	708 0.9×	319 0.8×	594 1.7×	224 0.9×	38	2.0k
Eline van der Burg Netherlands	13	1.2k 0.9×	1.3k 1.6×	262 0.6×	342 1.0×	134 0.6×	19	1.7k
Haihui Lu United States	17	1.6k 1.3×	793 1.0×	355 0.9×	152 0.4×	370 1.5×	27	2.1k
Puay Leng Lee Singapore	17	1.6k 1.3×	512 0.6×	525 1.3×	126 0.4×	248 1.0×	18	2.1k

Countries citing papers authored by Christiaan Klijn

Since Specialization

Citations

This map shows the geographic impact of Christiaan Klijn's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christiaan Klijn with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christiaan Klijn more than expected).

Fields of papers citing papers by Christiaan Klijn

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christiaan Klijn. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christiaan Klijn. The network helps show where Christiaan Klijn may publish in the future.

Co-authorship network of co-authors of Christiaan Klijn

This figure shows the co-authorship network connecting the top 25 collaborators of Christiaan Klijn. A scholar is included among the top collaborators of Christiaan Klijn based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christiaan Klijn. Christiaan Klijn is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Hagenbeek, Thijs J., Ho-June Lee, Jason Li, et al.. (2020). Machine-Learning and Chemicogenomics Approach Defines and Predicts Cross-Talk of Hippo and MAPK Pathways. Cancer Discovery. 11(3). 778–793. 37 indexed citations

Dominguez, Claudia X., Sören Müller, Shilpa Keerthivasan, et al.. (2019). Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy. Cancer Discovery. 10(2). 232–253. 522 indexed citations breakdown →

Yen, Ivana, Fergus Shanahan, Mark Merchant, et al.. (2018). Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors. Cancer Cell. 34(4). 611–625.e7. 47 indexed citations

Dompe, Nicholas, Christiaan Klijn, Jenna Port, et al.. (2018). A CRISPR screen identifies MAPK7 as a target for combination with MEK inhibition in KRAS mutant NSCLC. PLoS ONE. 13(6). e0199264–e0199264. 22 indexed citations

Lee, Ho-June, Yi Cao, Victoria C. Pham, et al.. (2017). Ras–MEK Signaling Mediates a Critical Chk1-Dependent DNA Damage Response in Cancer Cells. Molecular Cancer Therapeutics. 16(4). 694–704. 16 indexed citations

Foster, Scott A., Christiaan Klijn, & Shiva Malek. (2016). Tissue-Specific Mutations in BRAF and EGFR Necessitate Unique Therapeutic Approaches. Trends in cancer. 2(12). 699–701. 4 indexed citations

Yu, Mamie, Suresh Selvaraj, Genee Lee, et al.. (2015). A resource for cell line authentication, annotation and quality control. Nature. 520(7547). 307–311. 143 indexed citations

Vollebergh, Marieke A., Christiaan Klijn, Philip C. Schouten, et al.. (2014). Lack of Genomic Heterogeneity at High-Resolution aCGH between Primary Breast Cancers and Their Paired Lymph Node Metastases. PLoS ONE. 9(8). e103177–e103177. 7 indexed citations

Bouwman, Peter, Hanneke van der Gulden, Ingrid van der Heijden, et al.. (2013). A High-Throughput Functional Complementation Assay for Classification of BRCA1 Missense Variants. Cancer Discovery. 3(10). 1142–1155. 92 indexed citations

10.

Klijn, Christiaan, Marco J. Koudijs, Jaap Kool, et al.. (2013). Analysis of Tumor Heterogeneity and Cancer Gene Networks Using Deep Sequencing of MMTV-Induced Mouse Mammary Tumors. PLoS ONE. 8(5). e62113–e62113. 18 indexed citations

11.

Bowman-Colin, Christian, Bing Xia, Samuel F. Bunting, et al.. (2013). Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer. Proceedings of the National Academy of Sciences. 110(21). 8632–8637. 52 indexed citations

12.

Doornebal, Chris W., Sjoerd Klarenbeek, Tanya M. Braumuller, et al.. (2012). A Preclinical Mouse Model of Invasive Lobular Breast Cancer Metastasis. Cancer Research. 73(1). 353–363. 55 indexed citations

13.

Drost, Rinske, Peter Bouwman, Sven Rottenberg, et al.. (2011). BRCA1 RING Function Is Essential for Tumor Suppression but Dispensable for Therapy Resistance. Cancer Cell. 20(6). 797–809. 197 indexed citations

14.

Koudijs, Marco J., Christiaan Klijn, Jaap Kool, et al.. (2011). High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors. Genome Research. 21(12). 2181–2189. 32 indexed citations

15.

Bouwman, Peter, Rinske Drost, Christiaan Klijn, et al.. (2011). Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression. The Journal of Pathology. 224(1). 10–21. 26 indexed citations

16.

Bruin, S., Yao He, Gerrit‐Jan Liefers, et al.. (2011). Molecular alterations associated with liver metastases development in colorectal cancer patients. British Journal of Cancer. 105(2). 281–287. 27 indexed citations

17.

Horlings, Hugo M., Carmen Lai, Dimitry S.A. Nuyten, et al.. (2010). Integration of DNA Copy Number Alterations and Prognostic Gene Expression Signatures in Breast Cancer Patients. Clinical Cancer Research. 16(2). 651–663. 48 indexed citations

18.

Holstege, Henne, Arno Velds, Xiaoling Liu, et al.. (2010). Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers. BMC Cancer. 10(1). 455–455. 32 indexed citations

19.

Varela, Ignacio, Christiaan Klijn, P. J. Stephens, et al.. (2010). Somatic structural rearrangements in genetically engineered mouse mammary tumors. Genome biology. 11(10). R100–R100. 19 indexed citations

20.

Klijn, Christiaan, Jan Bot, David J. Adams, et al.. (2009). Identification of Networks of Co-Occurring, Tumor-Related DNA Copy Number Changes Using a Genome-Wide Scoring Approach. PLoS Computational Biology. 6(1). e1000631–e1000631. 25 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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