Christiaan Klijn

4.6k citations

30 papers · 1.8k indexed · 1 hit paper · h-index 20

Oncology top 5%
Cancer Research top 5%
- Cancer Genomics and Diagnostics 10
Molecular Biology top 10%
- DNA Repair Mechanisms 6
- Gene expression and cancer classification 4
- Genomics and Chromatin Dynamics 4
- Epigenetics and DNA Methylation 3
Genetics top 5%
- BRCA gene mutations in cancer 6
- Genomic variations and chromosomal abnormalities 5
Immunology top 10%
Pathology and Forensic Medicine
- Genetic factors in colorectal cancer 3

Co-authors: Jos Jonkers Richard Bourgon Lodewyk F.A. Wessels Zora Modrušan Hartmut Koeppen Sarah Gierke Melissa R. Junttila Shannon J. Turley
Cited by: Oncology Cancer Research Molecular Biology
Journals: PLoS ONE (4 papers)Cancer Discovery (3 papers)Cancer Cell (2 papers)
Partner nations: Netherlands United Kingdom France

In The Last Decade

Christiaan Klijn

29 papers receiving 1.8k citations

Hit Papers

align trajectories log scale

Peers

Countries citing papers authored by Christiaan Klijn

Since Specialization

Citations

This map shows the geographic impact of Christiaan Klijn's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christiaan Klijn with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christiaan Klijn more than expected).

Fields of papers citing papers by Christiaan Klijn

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christiaan Klijn. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christiaan Klijn. The network helps show where Christiaan Klijn may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Christiaan Klijn, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Christiaan Klijn Line = papers co-authored together Christiaan Klijn links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Machine-Learning and Chemicogenomics Approach Defines and Predicts Cross-Talk of Hippo and MAPK Pathways Cancer Discovery ·Gregory Woolston,Thijs J. Hagenbeek,Ho-June Lee,Jason Li,Christopher M. Rose,Eva Lin,Mamie Yu,Scott E. Martin,Robert Piskol,Jennifer A. Lacap,Deepak Sampath,Victoria C. Pham,Zora Modrušan,Jennie R. Lill,Christiaan Klijn,Shiva Malek,Matthew T. Chang,Anwesha Dey	2020	37
2	Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapybreakdown → Cancer Discovery ·Claudia X. Dominguez,Sören Müller,Shilpa Keerthivasan,Hartmut Koeppen,Jeffrey Hung,Sarah Gierke,Nitin S Deshpande,Oded Foreman,Travis W. Bainbridge,Alessandra Castiglioni,Yasin Şenbabaoğlu,Zora Modrušan,Yuxin Liang,Melissa R. Junttila,Christiaan Klijn,Richard Bourgon,Shannon J. Turley	2019	522
3	A CRISPR screen identifies MAPK7 as a target for combination with MEK inhibition in KRAS mutant NSCLC PLoS ONE ·Nicholas Dompe,Christiaan Klijn,Anthony Akuribire Ayambire,Z. Li,Jenna Port,Trinna Cuellar,Colin Watanabe,Benjamin Haley,Richard M. Neve,Marie Evangelista,David Stokoe	2018	22
4	Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors Cancer Cell ·Ivana Yen,Fergus Shanahan,Mark Merchant,Christine Orr,Thomas Hunsaker,Matthew R. Durk,Hank La,Xiaolin Zhang,Scott E. Martin,Eva Lin,John S.D. Chan,Yihong Yu,Dhara N. Amin,Richard M. Neve,Amy Gustafson,Avinashnarayan Venkatanarayan,Scott A. Foster,Joachim Rudolph,Christiaan Klijn,Shiva Malek	2018	47
5	Ras–MEK Signaling Mediates a Critical Chk1-Dependent DNA Damage Response in Cancer Cells Molecular Cancer Therapeutics ·Ho-June Lee,Yi Cao,Victoria C. Pham,Elizabeth Blackwood,Catherine Wilson,Marie Evangelista,Christiaan Klijn,David Stokoe,Jeff Settleman	2017	16
6	Tissue-Specific Mutations in BRAF and EGFR Necessitate Unique Therapeutic Approaches Trends in cancer ·Scott A. Foster,Christiaan Klijn,Shiva Malek	2016	4
7	A resource for cell line authentication, annotation and quality control Nature ·Mamie Yu,Suresh Selvaraj,L. P. Garrod,Gabriel Fernandez Santos,川畑隆之,利行厚美,Genee Lee,Franklin Peale,Christiaan Klijn,Richard Bourgon,Joshua S. Kaminker,Richard M. Neve	2015	143
8	Lack of Genomic Heterogeneity at High-Resolution aCGH between Primary Breast Cancers and Their Paired Lymph Node Metastases PLoS ONE ·Marieke A. Vollebergh,Christiaan Klijn,Philip C. Schouten,Jelle Wesseling,R. N. Rocha,Bauke Ylstra,Lodewyk F.A. Wessels,Jos Jonkers,Sabine C. Linn	2014	7
9	A High-Throughput Functional Complementation Assay for Classification of BRCA1 Missense Variants Cancer Discovery ·Peter Bouwman,Hanneke van der Gulden,Ingrid van der Heijden,Rinske Drost,Christiaan Klijn,Pramudita R. Prasetyanti,Mark Pieterse,Ellen Wientjens,Jost Seibler,Frans B.L. Hogervorst,Jos Jonkers	2013	92
10	Analysis of Tumor Heterogeneity and Cancer Gene Networks Using Deep Sequencing of MMTV-Induced Mouse Mammary Tumors PLoS ONE ·Christiaan Klijn,Marco J. Koudijs,Jaap Kool,Jelle ten Hoeve,Mandy Boer,P D Purwanti,Waseem Akhtar,L.F. Manuel,D. DeBeer,Marcel Reinders,David J. Adams,Maarten van Lohuizen,John Hilkens,Lodewyk F.A. Wessels,Jos Jonkers	2013	18
11	A Preclinical Mouse Model of Invasive Lobular Breast Cancer Metastasis Cancer Research ·Chris W. Doornebal,Sjoerd Klarenbeek,Tanya M. Braumuller,Christiaan Klijn,Metamia Ciampricotti,Cheei‐Sing Hau,Markus W. Hollmann,Jos Jonkers,Karin E. de Visser	2012	55
12	BRCA1 RING Function Is Essential for Tumor Suppression but Dispensable for Therapy Resistance Cancer Cell ·Rinske Drost,Peter Bouwman,Sven Rottenberg,Ute Boon,Eva Schut,Sjoerd Klarenbeek,Christiaan Klijn,Ingrid van der Heijden,Hanneke van der Gulden,Ellen Wientjens,Mark Pieterse,Aurélie Catteau,Peter Green,Ellen Solomon,Joanna R. Morris,Jos Jonkers	2011	197
13	High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors Genome Research ·Marco J. Koudijs,Christiaan Klijn,洋一郎志村,Jaap Kool,Jelle ten Hoeve,Daoud Sie,Pramudita R. Prasetyanti,Eva Schut,Sjors M. Kas,محمود رضا جعفری,Edwin Cuppen,Lodewyk F.A. Wessels,David J. Adams,Jos Jonkers	2011	32
14	Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression The Journal of Pathology ·Peter Bouwman,Rinske Drost,Christiaan Klijn,Mark Pieterse,Hanneke van der Gulden,Ji‐Ying Song,Károly Szuhai,Jos Jonkers	2011	26
15	Integration of DNA Copy Number Alterations and Prognostic Gene Expression Signatures in Breast Cancer Patients Clinical Cancer Research ·Hugo M. Horlings,Carmen Lai,Dimitry S.A. Nuyten,Hans Halfwerk,Petra Kristel,Roundtable on Obesity Solutions,Simon A. Joosse,Christiaan Klijn,Petra M. Nederlof,Marcel Reinders,Lodewyk F.A. Wessels,Marc J. van de Vijver	2010	48
16	Somatic structural rearrangements in genetically engineered mouse mammary tumors Genome biology ·Ignacio Varela,Christiaan Klijn,P. J. Stephens,Laura Mudie,Lucy Stebbings,Jonghwan Kim,Hanneke van der Gulden,Eva Schut,Sjoerd Klarenbeek,Peter J. Campbell,Lodewyk F.A. Wessels,Michael R. Stratton,Jos Jonkers,P. Andrew Futreal,David J. Adams	2010	19
17	Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers BMC Cancer ·Henne Holstege,Roundtable on Obesity Solutions,Arno Velds,Xiaoling Liu,Simon A. Joosse,Sjoerd Klarenbeek,Eva Schut,Ron Kerkhoven,Christiaan Klijn,Lodewyk F.A. Wessels,Petra M. Nederlof,Jos Jonkers	2010	32
18	Identification of Networks of Co-Occurring, Tumor-Related DNA Copy Number Changes Using a Genome-Wide Scoring Approach PLoS Computational Biology ·Christiaan Klijn,Jan Bot,David J. Adams,Marcel Reinders,Lodewyk F.A. Wessels,Jos Jonkers	2009	25
19	Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data Nucleic Acids Research ·Christiaan Klijn,Henne Holstege,Jeroen de Ridder,Xiaoling Liu,Marcel Reinders,Jos Jonkers,Lodewyk F.A. Wessels	2008	59
20	Module-Based Outcome Prediction Using Breast Cancer Compendia PLoS ONE ·Martin H. van Vliet,Christiaan Klijn,Lodewyk F.A. Wessels,Marcel Reinders	2007	15

About Christiaan Klijn

Christiaan Klijn is a scholar working on Cancer Research, Genetics, Molecular Biology, Oncology and Pathology and Forensic Medicine, having authored 30 papers that have together received 1.8k indexed citations. Recurring topics across this work include Cancer Genomics and Diagnostics (10 papers), DNA Repair Mechanisms (6 papers), BRCA gene mutations in cancer (6 papers), Genomic variations and chromosomal abnormalities (5 papers), Gene expression and cancer classification (4 papers), Genomics and Chromatin Dynamics (4 papers), Epigenetics and DNA Methylation (3 papers) and Genetic factors in colorectal cancer (3 papers). The work is most often cited by research in Oncology (813 citations), Cancer Research (407 citations), Molecular Biology (1.2k citations), Genetics (342 citations) and Immunology (239 citations). Christiaan Klijn has collaborated with scholars based in Netherlands, United Kingdom and France. Frequent co-authors include Jos Jonkers, Richard Bourgon, Lodewyk F.A. Wessels, Zora Modrušan, Hartmut Koeppen, Sarah Gierke, Melissa R. Junttila, Shannon J. Turley, Sören Müller and Yasin Şenbabaoğlu. Their work appears in journals such as PLoS ONE, Cancer Discovery, Cancer Cell, BMC Cancer and Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact