Len Stephens

24.5k total citations · 7 hit papers
177 papers, 19.1k citations indexed

About

Len Stephens is a scholar working on Molecular Biology, Cell Biology and Immunology. According to data from OpenAlex, Len Stephens has authored 177 papers receiving a total of 19.1k indexed citations (citations by other indexed papers that have themselves been cited), including 117 papers in Molecular Biology, 54 papers in Cell Biology and 45 papers in Immunology. Recurrent topics in Len Stephens's work include Protein Kinase Regulation and GTPase Signaling (77 papers), PI3K/AKT/mTOR signaling in cancer (42 papers) and Cellular transport and secretion (41 papers). Len Stephens is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (77 papers), PI3K/AKT/mTOR signaling in cancer (42 papers) and Cellular transport and secretion (41 papers). Len Stephens collaborates with scholars based in United Kingdom, United States and Canada. Len Stephens's co-authors include Phillip T. Hawkins, Karen E. Anderson, Trevor Jackson, Roger Williams, Olga Perišić, Edward H. Walker, John Coadwell, Keith Davidson, Bart Vanhaesebroeck and Robin F. Irvine and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Len Stephens

175 papers receiving 18.9k citations

Hit Papers

Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in ... 1994 2026 2004 2015 1997 2000 1998 2012 1994 250 500 750 1000
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B
    1997 1.0k citations Len Stephens, Phillip T. Hawkins et al. profile →
  2. Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine
    2000 991 citations Michael E. Pacold, Olga Perišić et al. profile →
  3. Protein Kinase B Kinases That Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Activation of Protein Kinase B
    1998 909 citations Len Stephens, Karen E. Anderson et al. profile →
  4. PI3K signalling: the path to discovery and understanding
    2012 744 citations Len Stephens, Phillip T. Hawkins et al. profile →
  5. A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits
    1994 504 citations Len Stephens, Phillip T. Hawkins et al. profile →
  6. Crystal Structure and Functional Analysis of Ras Binding to Its Effector Phosphoinositide 3-Kinase γ
    2000 504 citations Michael E. Pacold, Sabine Suire et al. profile →
  7. PI3K signalling in inflammation
    2014 410 citations Phillip T. Hawkins, Len Stephens profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Len Stephens United Kingdom 67 13.3k 4.7k 3.9k 2.1k 1.6k 177 19.1k
Phillip T. Hawkins United Kingdom 66 12.8k 1.0× 4.5k 1.0× 3.7k 1.0× 2.0k 1.0× 1.6k 1.0× 181 18.7k
Alex Toker United States 73 15.1k 1.1× 3.7k 0.8× 2.3k 0.6× 3.1k 1.5× 1.4k 0.9× 136 20.5k
Matthias P. Wymann Switzerland 58 9.0k 0.7× 1.7k 0.4× 3.9k 1.0× 1.9k 0.9× 1.4k 0.9× 138 14.6k
Jonathan Backer United States 71 12.6k 0.9× 4.8k 1.0× 1.7k 0.4× 1.7k 0.8× 2.0k 1.3× 147 17.4k
Bart Vanhaesebroeck United Kingdom 68 14.4k 1.1× 2.6k 0.6× 5.7k 1.5× 4.1k 2.0× 1.5k 1.0× 194 22.4k
Rony Seger Israel 70 14.9k 1.1× 3.1k 0.7× 2.5k 0.6× 4.2k 2.0× 1.3k 0.9× 206 22.2k
Bernard Payrastre France 64 7.1k 0.5× 3.3k 0.7× 1.6k 0.4× 994 0.5× 899 0.6× 270 12.9k
Marek Michalak Canada 75 11.0k 0.8× 9.3k 2.0× 5.2k 1.3× 1.2k 0.6× 1.4k 0.9× 297 20.2k
David P. Siderovski United States 62 13.7k 1.0× 2.7k 0.6× 2.3k 0.6× 1.9k 0.9× 1.2k 0.8× 176 17.9k
J. Justin Hsuan United Kingdom 52 8.0k 0.6× 3.1k 0.7× 1.7k 0.4× 1.6k 0.8× 1.7k 1.1× 97 11.9k

Countries citing papers authored by Len Stephens

Since Specialization
Citations

This map shows the geographic impact of Len Stephens's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Len Stephens with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Len Stephens more than expected).

Fields of papers citing papers by Len Stephens

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Len Stephens. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Len Stephens. The network helps show where Len Stephens may publish in the future.

Co-authorship network of co-authors of Len Stephens

This figure shows the co-authorship network connecting the top 25 collaborators of Len Stephens. A scholar is included among the top collaborators of Len Stephens based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Len Stephens. Len Stephens is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Chan, Pui Ying, Victoria Harle, Victoria Offord, et al.. (2023). Genome-wide CRISPR-Cas9 screening to identify CDS2 as an essential gene in uveal melanoma.. Journal of Clinical Oncology. 41(16_suppl). e21585–e21585. 1 indexed citations
2.
Han, Xu, Yang Mei, Rama K. Mishra, et al.. (2023). Targeting pleckstrin-2/Akt signaling reduces proliferation in myeloproliferative neoplasm models. Journal of Clinical Investigation. 133(6). 11 indexed citations
3.
Barneda, David, Len Stephens, & Phillip T. Hawkins. (2022). ARFs get the BioID treatment: what have we been missing?. The EMBO Journal. 41(17). e112181–e112181. 1 indexed citations
4.
Barneda, David, Izabella Niewczas, D.M. Collins, et al.. (2022). Acyl chain selection couples the consumption and synthesis of phosphoinositides. The EMBO Journal. 41(18). e110038–e110038. 17 indexed citations
5.
Pacheco, Jonathan, Neha Chauhan, Jonathan Clark, et al.. (2022). Kinase-independent synthesis of 3-phosphorylated phosphoinositides by a phosphotransferase. Nature Cell Biology. 24(5). 708–722. 24 indexed citations
6.
Durrant, Tom N., Tamara Chessa, Sabine Suire, et al.. (2018). Quantitation of class IA PI3Ks in mice reveals p110-free-p85s and isoform-selective subunit associations and recruitment to receptors. Proceedings of the National Academy of Sciences. 115(48). 12176–12181. 38 indexed citations
7.
Durrant, Tom N., James L. Hutchinson, Kate J. Heesom, et al.. (2017). In-depth PtdIns(3,4,5)P3 signalosome analysis identifies DAPP1 as a negative regulator of GPVI-driven platelet function. Blood Advances. 1(14). 918–932. 30 indexed citations
8.
9.
Lindsay, Yvonne, Tamara Chessa, Hervé Guillou, et al.. (2015). Localizing the lipid products of PI3Kγ in neutrophils. Advances in Biological Regulation. 60. 36–45. 11 indexed citations
10.
Clark, Jonathan, Robert R. Kay, Anna Kielkowska, et al.. (2014). Dictyostelium uses ether‐linked inositol phospholipids for intracellular signalling. The EMBO Journal. 33(19). 2188–2200. 47 indexed citations
11.
Hoeller, Oliver, Parvin Bolourani, Jonathan Clark, et al.. (2013). Two distinct functions for PI3-kinases in macropinocytosis. Journal of Cell Science. 126(Pt 18). 4296–307. 80 indexed citations
12.
Du, Cheng‐Jin, John G. Ferguson, Phillip T. Hawkins, Len Stephens, & Till Bretschneider. (2012). Fast random walker for neutrophil cell segmentation in 3D. 3765. 190–193. 4 indexed citations
13.
Hawkins, Phillip T., Len Stephens, Sabine Suire, & Michael Wilson. (2010). PI3K Signaling in Neutrophils. Current topics in microbiology and immunology. 346. 183–202. 83 indexed citations
14.
Anderson, Karen E., Keith B. Boyle, Keith Davidson, et al.. (2008). CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks. Blood. 112(13). 5202–5211. 75 indexed citations
15.
Guillou, Hervé, Len Stephens, & Phillip T. Hawkins. (2007). Quantitative Measurement of Phosphatidylinositol 3,4,5-trisphosphate. Methods in enzymology on CD-ROM/Methods in enzymology. 434. 117–130. 29 indexed citations
16.
Condliffe, Alison M., Louise M. C. Webb, Gail Ferguson, et al.. (2006). RhoG Regulates the Neutrophil NADPH Oxidase. The Journal of Immunology. 176(9). 5314–5320. 32 indexed citations
17.
Perišić, Olga, Michael Wilson, Jerónimo Bravo, et al.. (2004). The role of phosphoinositides and phosphorylation in regulation of NADPH oxidase. Advances in Enzyme Regulation. 44(1). 279–298. 41 indexed citations
18.
Stephens, Len, Chris D. Ellson, & Phillip T. Hawkins. (2002). Roles of PI3Ks in leukocyte chemotaxis and phagocytosis. Current Opinion in Cell Biology. 14(2). 203–213. 209 indexed citations
19.
Cadwallader, Karen A., Alison M. Condliffe, Alex McGregor, et al.. (2002). Regulation of Phosphatidylinositol 3-Kinase Activity and Phosphatidylinositol 3,4,5-Trisphosphate Accumulation by Neutrophil Priming Agents. The Journal of Immunology. 169(6). 3336–3344. 50 indexed citations
20.
Ellson, Chris D., Karen E. Anderson, Graham Morgan, et al.. (2001). Phosphatidylinositol 3-phosphate is generated in phagosomal membranes. Current Biology. 11(20). 1631–1635. 138 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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