Kym N. Lowes

3.8k citations

29 papers · 1.4k indexed · h-index 15

Molecular Biology
Hepatology top 2%
Epidemiology top 10%
Surgery top 10%
Public Health, Environmental and Occupational Health top 10%

Co-authors: George C. Yeoh John K. Olynyk Barbara A. Brennan Lawrence J. Abraham Brad E. Sleebs David C.S. Huang Emma Croager Alan F. Cowman
Topics: Malaria Research and Control (12 papers)Computational Drug Discovery Methods (6 papers)Cell death mechanisms and regulation (5 papers)
Cited by: Hepatology Molecular Biology Immunology
Journals: Nature Communications Molecular Cell Gut
Partner nations: Australia United States Switzerland

In The Last Decade

Kym N. Lowes

28 papers receiving 1.4k citations

Peers

Countries citing papers authored by Kym N. Lowes

Since Specialization

Citations

This map shows the geographic impact of Kym N. Lowes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kym N. Lowes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kym N. Lowes more than expected).

Fields of papers citing papers by Kym N. Lowes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kym N. Lowes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kym N. Lowes. The network helps show where Kym N. Lowes may publish in the future.

Co-authorship network of co-authors of Kym N. Lowes

This figure shows the co-authorship network connecting the top 25 collaborators of Kym N. Lowes. A scholar is included among the top collaborators of Kym N. Lowes based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kym N. Lowes. Kym N. Lowes is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Mutational profiling of SARS-CoV-2 papain-like protease reveals requirements for function, structure, and drug escape 2024 ·Nature Communications ·(unknown),(unknown),(unknown),Nathan W. Kuchel,Bernadine G.C. Lu,(unknown),Kym N. Lowes,Dale J. Calleja,Jeffrey P. Mitchell,Guillaume Lessène,David Komander,Matthew E. Call,Melissa Call	5
2	Structure-based development of potent Plasmodium falciparum M1 and M17 aminopeptidase selective and dual inhibitors via S1′-region optimisation 2022 ·European Journal of Medicinal Chemistry ·(unknown),(unknown),Chaille T. Webb,(unknown),Anna Ngo,Kym N. Lowes,Nyssa Drinkwater,Sheena McGowan,Peter J. Scammells	4
3	The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL 2022 ·Cell Death and Disease ·Annette V. Jacobsen,(unknown),Kym N. Lowes,Amanda E. Au,Ying Zhang,Nima Etemadi,Cheree Fitzgibbon,Wilhelmus J. A. Kersten,André L. Samson,Mark F. van Delft,David C.S. Huang,Hélène Jousset Sabroux,Guillaume Lessène,John Silke,James M. Murphy	14
4	The Invention of WM382, a Highly Potent PMIX/X Dual Inhibitor toward the Treatment of Malaria 2022 ·ACS Medicinal Chemistry Letters ·Manuel de Lera Ruiz,Paola Favuzza,Zhuyan Guo,Lianyun Zhao,Bin Hu,Zhiyu Lei,(unknown),Nicholas Murgolo,Christopher W. Boyce,Marissa Vavrek,Jennifer K. Thompson,Anna Ngo,Kate E. Jarman,(unknown),Justin A. Boddey,Brad E. Sleebs,Kym N. Lowes,Alan F. Cowman,David B. Olsen,John A. McCauley	12
5	Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax 2022 ·Structure ·Anthony N. Hodder,(unknown),S.W. Scally,Tony Triglia,Anna Ngo,Richard W. Birkinshaw,(unknown),Paola Favuzza,Melanie H. Dietrich,Wai‐Hong Tham,Peter E. Czabotar,Kym N. Lowes,Zhuyan Guo,Nicholas Murgolo,Manuel de Lera Ruiz,John A. McCauley,Brad E. Sleebs,David B. Olsen,Alan F. Cowman	19
6	Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion 2021 ·European Journal of Medicinal Chemistry ·William Nguyen,Madeline G. Dans,Anna Ngo,(unknown),(unknown),Sandra Duffy,Tania F. de Koning‐Ward,Kym N. Lowes,Hélène Jousset Sabroux,Vicky M. Avery,Danny W. Wilson,Paul R. Gilson,Brad E. Sleebs	14
7	Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3 2019 ·Cell Reports ·Emma J. Petrie,Jarrod J. Sandow,(unknown),Lung‐Yu Liang,(unknown),Samuel N. Young,Wilhelmus J. A. Kersten,Cheree Fitzgibbon,André L. Samson,Annette V. Jacobsen,Kym N. Lowes,Amanda E. Au,Hélène Jousset Sabroux,Najoua Lalaoui,Andrew I. Webb,Guillaume Lessène,Gerard Manning,Isabelle S. Lucet,James M. Murphy	88
8	Exploration of the P3 region of PEXEL peptidomimetics leads to a potent inhibitor of the Plasmodium protease, plasmepsin V 2016 ·Bioorganic & Medicinal Chemistry ·Michelle Gazdik,Kate E. Jarman,Matthew T. O’Neill,Anthony N. Hodder,Kym N. Lowes,Hélène Jousset Sabroux,Alan F. Cowman,Justin A. Boddey,Brad E. Sleebs	10
9	HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death 2016 ·Cell Death and Disease ·Annette V. Jacobsen,Kym N. Lowes,Maria C. Tanzer,Isabelle S. Lucet,Joanne M. Hildebrand,Emma J. Petrie,Mark F. van Delft,Zikou Liu,Stephanie A. Conos,Jian‐Guo Zhang,David C.S. Huang,John Silke,Guillaume Lessène,James M. Murphy	131
10	Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes 2015 ·Nature Structural & Molecular Biology ·Anthony N. Hodder,Brad E. Sleebs,Peter E. Czabotar,Michelle Gazdik,Yibin Xu,Matthew T. O’Neill,Sash Lopaticki,Thomas Nebl,Tony Triglia,Brian J. Smith,Kym N. Lowes,Justin A. Boddey,Alan F. Cowman	73
11	Inhibition of Plasmepsin V Activity Demonstrates Its Essential Role in Protein Export, PfEMP1 Display, and Survival of Malaria Parasites 2014 ·PLoS Biology ·Brad E. Sleebs,Sash Lopaticki,Danushka S. Marapana,Matthew T. O’Neill,(unknown),Michelle Gazdik,Svenja Günther,Lachlan Whitehead,Kym N. Lowes,Lea Barfod,Lars Hviid,Philip J. Shaw,Anthony N. Hodder,Brian J. Smith,Alan F. Cowman,Justin A. Boddey	113
12	Transition State Mimetics of the Plasmodium Export Element Are Potent Inhibitors of Plasmepsin V from P. falciparum and P. vivax 2014 ·Journal of Medicinal Chemistry ·Brad E. Sleebs,Michelle Gazdik,Matthew T. O’Neill,(unknown),Sash Lopaticki,Kurt Lackovic,Kym N. Lowes,Brian J. Smith,Alan F. Cowman,Justin A. Boddey	41
13	Quinazoline Sulfonamides as Dual Binders of the Proteins B-Cell Lymphoma 2 and B-Cell Lymphoma Extra Long with Potent Proapoptotic Cell-Based Activity 2011 ·Journal of Medicinal Chemistry ·Brad E. Sleebs,Peter E. Czabotar,Wayne J. Fairbrother,W. Douglas Fairlie,John A. Flygare,David C.S. Huang,Wilhelmus J. A. Kersten,Michael F. T. Koehler,Guillaume Lessène,Kym N. Lowes,John P. Parisot,Brian J. Smith,Morey L. Smith,Andrew J. Souers,Ian P. Street,Hong Yang,Jonathan B. Baell	60
14	βTrCP- and Rsk1/2-Mediated Degradation of BimEL Inhibits Apoptosis 2009 ·Molecular Cell ·(unknown),Florian Bassermann,Daniele Guardavaccaro,Gaia Vasiliver-Shamis,Michael S. Cohen,Kym N. Lowes,Michael L. Dustin,David C.S. Huang,Jack Taunton,Michele Pagano	155
15	Effective detection of corrected dystrophin loci inmdxmouse myogenic precursors 2007 ·Human Mutation ·Marian Todaro,Anita Quigley,Magdalena Kita,(unknown),Kym N. Lowes,Andrew J. Kornberg,Mark Cook,Robert M. I. Kapsa	16
16	Hepatic expression of the tumor necrosis factor family member lymphotoxin‐β is regulated by interleukin (IL)‐6 and IL‐1β: transcriptional control mechanisms in oval cells and hepatoma cell lines 2005 ·Liver International ·Lily S. Subrata,Kym N. Lowes,John K. Olynyk,George C. Yeoh,Elizabeth Quail,Lawrence J. Abraham	23
17	DNA electroporation in vivo targets mature fibres in dystrophic mdx muscle 2005 ·Neuromuscular Disorders ·(unknown),Kym N. Lowes,Anita Quigley,Rosetta Marotta,Magdalena Kita,Edward Byrne,Andrew J. Kornberg,Mark Cook,Robert M. I. Kapsa	12
18	Upregulation of lymphotoxin β expression in liver progenitor (oval) cells in chronic hepatitis C 2003 ·Gut ·Kym N. Lowes,(unknown),(unknown),(unknown),(unknown)	47
19	Oval cell‐mediated liver regeneration: Role of cytokines and growth factors 2002 ·Journal of Gastroenterology and Hepatology ·Kym N. Lowes,Emma Croager,John K. Olynyk,Lawrence J. Abraham,George C. Yeoh	133
20	Oval Cell Numbers in Human Chronic Liver Diseases Are Directly Related to Disease Severity 1999 ·American Journal Of Pathology ·Kym N. Lowes,Barbara A. Brennan,George C. Yeoh,John K. Olynyk	353

About Kym N. Lowes

Kym N. Lowes is a scholar working on Hepatology, Public Health, Environmental and Occupational Health and Computational Theory and Mathematics, having authored 29 papers that have together received 1.4k indexed citations. Recurring topics across this work include Malaria Research and Control (12 papers), Computational Drug Discovery Methods (6 papers) and Cell death mechanisms and regulation (5 papers). The work is most often cited by research in Hepatology (427 citations), Molecular Biology (657 citations) and Immunology (201 citations). Kym N. Lowes has collaborated with scholars based in Australia, United States and Switzerland. Frequent co-authors include George C. Yeoh, John K. Olynyk, Barbara A. Brennan, Lawrence J. Abraham, Brad E. Sleebs, David C.S. Huang, Emma Croager, Alan F. Cowman, Brian J. Smith and Justin A. Boddey. Their work appears in journals such as Nature Communications, Molecular Cell and Gut.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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