Daniel W. Nebert

57.9k total citations · 20 hit papers
488 papers, 45.9k citations indexed

About

Daniel W. Nebert is a scholar working on Molecular Biology, Pharmacology and Cancer Research. According to data from OpenAlex, Daniel W. Nebert has authored 488 papers receiving a total of 45.9k indexed citations (citations by other indexed papers that have themselves been cited), including 207 papers in Molecular Biology, 198 papers in Pharmacology and 162 papers in Cancer Research. Recurrent topics in Daniel W. Nebert's work include Pharmacogenetics and Drug Metabolism (189 papers), Carcinogens and Genotoxicity Assessment (148 papers) and Drug Transport and Resistance Mechanisms (80 papers). Daniel W. Nebert is often cited by papers focused on Pharmacogenetics and Drug Metabolism (189 papers), Carcinogens and Genotoxicity Assessment (148 papers) and Drug Transport and Resistance Mechanisms (80 papers). Daniel W. Nebert collaborates with scholars based in United States, Cameroon and Hungary. Daniel W. Nebert's co-authors include Frank J. Gonzalez, Timothy P. Dalton, Harry V. Gelboin, Vasilis Vasiliou, Alvaro Puga, David W. Russell, David R. Nelson, Howard G. Shertzer, Shioko Kimura and Minor J. Coon and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Daniel W. Nebert

486 papers receiving 43.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature

1996 2.4k citations David R. Nelson, Michael R. Waterman et al. profile →
Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

1968 1.6k citations Daniel W. Nebert, Harry V. Gelboin profile →
P450 GENES: STRUCTURE, EVOLUTION, AND REGULATION

1987 1.3k citations Daniel W. Nebert, Frank J. Gonzalez profile →
Clinical importance of the cytochromes P450

2002 1.1k citations Daniel W. Nebert et al. profile →
The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

1997 985 citations Ida S. Owens, Daniel W. Nebert et al. profile →
Role of Aryl Hydrocarbon Receptor-mediated Induction of the CYP1 Enzymes in Environmental Toxicity and Cancer

2004 953 citations Daniel W. Nebert, Timothy P. Dalton et al. profile →
The P450 Superfamily: Update on New Sequences, Gene Mapping, and Recommended Nomenclature

1991 904 citations Daniel W. Nebert, David R. Nelson et al. profile →
Immune System Impairment and Hepatic Fibrosis in Mice Lacking the Dioxin-Binding Ah Receptor

1995 898 citations Shioko Kimura, Daniel W. Nebert et al. profile →
Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis

2000 813 citations Daniel W. Nebert, Timothy P. Dalton et al. profile →
Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants

2003 785 citations David R. Nelson, Daniel W. Nebert et al. profile →
The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis

2006 756 citations Daniel W. Nebert, Timothy P. Dalton profile →
The P450 Gene Superfamily: Recommended Nomenclature

1987 657 citations Daniel W. Nebert, Milton Adesnik et al. DNA profile →
Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily

2005 653 citations Ida S. Owens, Daniel W. Nebert et al. profile →
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents.

1989 620 citations Daniel W. Nebert et al. profile →
Human ATP-binding cassette (ABC) transporter family

2008 572 citations Daniel W. Nebert et al. profile →
Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

1988 548 citations Frank J. Gonzalez, Shioko Kimura et al. profile →
The P450 Superfamily: Updated Listing of All Genes and Recommended Nomenclature for the Chromosomal Loci

1989 521 citations Daniel W. Nebert, David R. Nelson et al. DNA profile →
Feedback control of AHR signalling regulates intestinal immunity

2017 403 citations Daniel W. Nebert et al. profile →
Human cytochromes P450 in health and disease

2013 376 citations Daniel W. Nebert et al. profile →
The in vivo and in vitro induction of aryl hydrocarbon hydroxylase in mammalian cells of different species, tissues, strains, and developmental and hormonal states

1969 362 citations Daniel W. Nebert, Harry V. Gelboin profile →

Peers

Countries citing papers authored by Daniel W. Nebert

Since Specialization

Citations

This map shows the geographic impact of Daniel W. Nebert's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Daniel W. Nebert with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Daniel W. Nebert more than expected).

Fields of papers citing papers by Daniel W. Nebert

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Daniel W. Nebert. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Daniel W. Nebert. The network helps show where Daniel W. Nebert may publish in the future.

Co-authorship network of co-authors of Daniel W. Nebert

This figure shows the co-authorship network connecting the top 25 collaborators of Daniel W. Nebert. A scholar is included among the top collaborators of Daniel W. Nebert based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Daniel W. Nebert. Daniel W. Nebert is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Cytochrome P450 1A1 (CYP1A1) protects against nonalcoholic fatty liver disease caused by Western diet containing benzo[a]pyrene in mice 2018 ·Food and Chemical Toxicology ·Shigeyuki Uno, Daniel W. Nebert, Makoto Makishima	51
2	Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes 2013 ·Proceedings of the National Academy of Sciences ·Jameel Iqbal, Li Sun, Jay Cao, Tony Yuen, Ping Lü, Itai Bab, N. Adrian Leu, Satish Srinivasan, Sagie Wagage, Christopher A. Hunter, Daniel W. Nebert, Mone Zaidi, Narayan G. Avadhani	99
3	The Aryl Hydrocarbon Receptor Functions as a Tumor Suppressor of Liver Carcinogenesis 2009 ·Cancer Research ·Yunxia Fan, Gregory P. Boivin, Erik S. Knudsen, Daniel W. Nebert, Ying Xia, Alvaro Puga	149
4	Olfactory Receptor Gene Polymorphisms and Nonallergic Vasomotor Rhinitis 2008 ·Journal of Asthma ·Jonathan A. Bernstein, Ge Zhang, Jin Li, (unknown), Daniel W. Nebert	9
5	The Vascular System as a Target of Metal Toxicity 2007 ·Toxicological Sciences ·Walter C. Prozialeck, Joshua Edwards, Daniel W. Nebert, James M. Woods, Aaron Barchowsky, William D. Atchison	251
6	Uroporphyria and hepatic carcinogenesis induced by polychlorinated biphenyls–iron interaction: Absence in the Cyp1a2(−/−) knockout mouse 2005 ·Biochemical and Biophysical Research Communications ·Peter Greaves, Bruce Clothier, Reginald Davies, (unknown), Richard Edwards, Timothy P. Dalton, Daniel W. Nebert, Andrew G. Smith	7
7	A novel allele in the promoter of the hepatic lipase is associated with increased concentration of HDL-C and decreased promoter activity 2002 ·Journal of Lipid Research ·Zhiguang Su, Sizhong Zhang, Daniel W. Nebert, Li Zhang, Dejia Huang, Yiping Hou, (unknown), Cuiying Xiao	16
8	Genetic Polymorphisms in Human Drug-Metabolizing Enzymes: Potential Uses of Reverse Genetics to Identify Genes of Toxicological Relevance 1997 ·Critical Reviews in Toxicology ·Alvaro Puga, Daniel W. Nebert, Ross A. McKinnon, Anil G. Menon	45
9	[1] P450 gene nomenclature based on evolution 1991 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Daniel W. Nebert, David R. Nelson	51
10	The P450 Superfamily: Updated Listing of All Genes and Recommended Nomenclature for the Chromosomal Loci breakdown → 1989 ·DNA ·Daniel W. Nebert, David R. Nelson, Milton Adesnik, Minor J. Coon, Ronald W. Estabrook, Frank J. Gonzalez, F. Peter Guengerich, I. C. Gunsalus, Eric F. Johnson, Byron Kemper, Wayne Levin, Ian Phillips, Ryo Sato, Michael R. Waterman	521
11	Transcriptional Start Site in the Mouse Cyp1a1 (Cytochrome P ₁ 450) Gene 1989 ·DNA ·John E. Jones, Daniel W. Nebert	1
12	Trout P450IA1: cDNA and Deduced Protein Sequence, Expression in Liver, and Evolutionary Significance 1988 ·DNA ·Larry J. Heilmann, (unknown), Sanford W. Bigelow, Daniel W. Nebert	186
13	Debrisoquine 4-Hydroxylase: Characterization of a New P450 Gene Subfamily, Regulation, Chromosomal Mapping, and Molecular Analysis of the DA Rat Polymorphism 1987 ·DNA ·Frank J. Gonzalez, Tamihide Matsunaga, Kiyoshi Nagata, Urs Meyer, Daniel W. Nebert, Jullia V. Pastewka, Christine A. Kozak, James R. Gillette, Harry V. Gelboin, James P. Hardwick	124
14	The P450 Gene Superfamily: Recommended Nomenclature breakdown → 1987 ·DNA ·Daniel W. Nebert, Milton Adesnik, Minor J. Coon, Ronald W. Estabrook, Frank J. Gonzalez, F. Peter Guengerich, I. C. Gunsalus, Eric F. Johnson, Byron Kemper, Wayne Levin, Ian Phillips, Ryo Sato, Michael R. Waterman	657
15	Dioxin-Inducible Enhancer Region Upstream from the Mouse P ₁ 450 Gene and Interaction with a Heterologous SV40 Promoter 1986 ·DNA ·(unknown), Frank J. Gonzalez, Anil K. Jaiswal, Daniel W. Nebert	49
16	Comparison of the Mouse P1450 Gene and Flanking Sequences from a MOPC 41 Plasmacytoma and Normal Liver 1985 ·DNA ·Shioko Kimura, Daniel W. Nebert	5
17	Characterization of a cDNA Clone for Mouse Phenobarbital-Inducible Cytochrome P-450b 1984 ·DNA ·Ieva Stupans, Toshihiko Ikeda, D. J. Kessler, Daniel W. Nebert	17
18	Cytochrome P ₁ -450 Structural Gene in Mouse, Rat, and Rabbit: Differences in DNA Methylation and Developmental Expression of mRNA* 1982 ·DNA ·Yuan‐Tsong Chen, Masahiko Negishi, Daniel W. Nebert	21
19	The Ah Locus, A Multigene Family Necessary for Survival in A Chemically Adverse Environment: Comparison With the Immune System 1982 ·Advances in genetics ·Daniel W. Nebert, Masahiko Negishi, Matti A. Lang, Leonard M. Hjelmeland, Howard J. Eisen	92
20	2,3,7,8-tetrachlorodibenzo-p-dioxin as cocarcinogen causing 3-methylcholanthrene-initiated subcutaneous tumors in mice genetically "nonresponsive" at Ah locus. 1978 ·Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·Richard E. Kouri, Thomas H. Rude, (unknown), Patrick M. Dansette, Donald M. Jerina, Steven A. Atlas, Ida S. Owens, Daniel W. Nebert	54

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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