James R. Gillette

18.1k total citations · 5 hit papers
184 papers, 14.8k citations indexed

About

James R. Gillette is a scholar working on Pharmacology, Molecular Biology and Oncology. According to data from OpenAlex, James R. Gillette has authored 184 papers receiving a total of 14.8k indexed citations (citations by other indexed papers that have themselves been cited), including 94 papers in Pharmacology, 46 papers in Molecular Biology and 29 papers in Oncology. Recurrent topics in James R. Gillette's work include Pharmacogenetics and Drug Metabolism (82 papers), Metabolism and Genetic Disorders (28 papers) and Drug Transport and Resistance Mechanisms (27 papers). James R. Gillette is often cited by papers focused on Pharmacogenetics and Drug Metabolism (82 papers), Metabolism and Genetic Disorders (28 papers) and Drug Transport and Resistance Mechanisms (27 papers). James R. Gillette collaborates with scholars based in United States, Sweden and Czechia. James R. Gillette's co-authors include David J. Jollow, Nicola Zampaglione, John R. Mitchell, B.B. Brodie, J.R. Mitchell, Hènry A. Sasame, William Z. Potter, Ryuichi Kato, Philippe L. Gigon and Theodore E. Gram and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

James R. Gillette

182 papers receiving 13.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Bromobenzene-Induced Liver Necrosis. Protective Role of Glutathione and Evidence for 3,4-Bromobenzene Oxide as the Hepatotoxic Metabolite

1974 2.9k citations James R. Gillette et al. profile →
ACETAMINOPHEN-INDUCED HEPATIC NECROSIS. IV. PROTECTIVE ROLE OF GLUTATHIONE

1973 1.5k citations J.R. Mitchell, James R. Gillette et al. Journal of Pharmacology and Experimental Therapeutics profile →
EFFECT OF STARVATION ON NADPH-DEPENDENT ENZYMES IN LIVER MICROSOMES OF MALE AND FEMALE RATS

1965 496 citations James R. Gillette et al. Journal of Pharmacology and Experimental Therapeutics profile →
Enzymatic Metabolism of Drugs and other Foreign Compounds

1958 368 citations B.B. Brodie, James R. Gillette et al. profile →
Microsomes and drug oxidation

1969 290 citations James R. Gillette et al. profile →

Peers

Countries citing papers authored by James R. Gillette

Since Specialization

Citations

This map shows the geographic impact of James R. Gillette's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James R. Gillette with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James R. Gillette more than expected).

Fields of papers citing papers by James R. Gillette

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James R. Gillette. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James R. Gillette. The network helps show where James R. Gillette may publish in the future.

Co-authorship network of co-authors of James R. Gillette

This figure shows the co-authorship network connecting the top 25 collaborators of James R. Gillette. A scholar is included among the top collaborators of James R. Gillette based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James R. Gillette. James R. Gillette is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Keynote Address: Man, Mice, Microsomes, Metabolites, and Mathematics 40 Years after the Revolution 1995 ·Drug Metabolism Reviews ·James R. Gillette	6
2	Inactivation of horseradish peroxidase by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine 1994 ·Chemical Research in Toxicology ·Katsumi Sugiyama, Amina S. Woods, Robert J. Cotter, R. J. Highet, John F. Darbyshire, Yoichi Osawa, James R. Gillette	2
3	Deuterium Isotope Effects on A-Ring and D-Ring Metabolism of Testosterone by CYP2C11: Evidence for Dissociation of Activated Enzyme-Substrate Complexes 1994 ·Biochemistry ·John F. Darbyshire, James R. Gillette, Kiyoshi Nagata, Katsumi Sugiyama	14
4	pH-Dependent One- and Two-Electron Oxidation of 3,5-Dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine Catalyzed by Horseradish Peroxidase 1994 ·Chemical Research in Toxicology ·(unknown), Maria Almira Correia, (unknown), (unknown), John F. Darbyshire, Yoichi Osawa, James R. Gillette	1
5	Theoretical studies on the mechanism of conversion of androgens to estrogens by aromatase 1991 ·Biochemistry ·Kenneth R. Korzekwa, William Trager, (unknown), Yoichi Osawa, James R. Gillette	27
6	Insights into deuterium isotope effects on the metabolism of steroid hormones and foreign compounds by cytochrome P-450 enzymes 1991 ·Life Sciences ·James R. Gillette	11
7	Mouse pulmonary cytochrome P-450 naphthalene hydroxylase: cDNA cloning, sequence, and expression in Saccharomyces cerevisiae 1991 ·Biochemistry ·Joseph K. Ritter, Ida S. Owens, Masahiko Negishi, Kiyoshi Nagata, Yhun Yhong Sheen, James R. Gillette, Hènry A. Sasame	42
8	Metabolism of the B-Ring of Testosterone by the Rat Cytochrome P-450 System 1989 ·Drug Metabolism Reviews ·Kenneth R. Korzekwa, Kiyoshi Nagata, William Trager, James R. Gillette	5
9	Debrisoquine 4-Hydroxylase: Characterization of a New P450 Gene Subfamily, Regulation, Chromosomal Mapping, and Molecular Analysis of the DA Rat Polymorphism 1987 ·DNA ·Frank J. Gonzalez, Tamihide Matsunaga, Kiyoshi Nagata, Urs Meyer, Daniel W. Nebert, Jullia V. Pastewka, Christine A. Kozak, James R. Gillette, Harry V. Gelboin, James P. Hardwick	124
10	The Problem of Chemically Reactive Metabolites 1982 ·Drug Metabolism Reviews ·James R. Gillette	19
11	Pharmacokinetic Factors Governing the Steady‐State Concentrations of Foreign Chemicals and Their Metabolites 1980 ·Novartis Foundation symposium ·James R. Gillette	5
12	Metabolism of [p-18O]-Phenacetin: The Mechanism of Activation of Phenacetin to Reactive Metabolites in Hamsters 1979 ·Molecular Pharmacology ·Jack Hinson, Sidney D. Nelson, James R. Gillette	33
13	Oxidation of alpha-methyldopa and other catechols by cytochrome P-450-generated superoxide anion: possible mechanism of methyldopa hepatitis. 1976 ·Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·Erik Dybing, Sidney D. Nelson, J.R. Mitchell, Hènry A. Sasame, James R. Gillette	130
14	The role of biotransformation in chemical-induced liver injury. 1976 ·Environmental Health Perspectives ·J. Mitchell, Wayne R. Snodgrass, James R. Gillette	59
15	RELATIONSHIP BETWEEN NADH AND NADPH OXIDATION DURING DRUG METABOLISM 1973 ·Drug Metabolism and Disposition ·Hènry A. Sasame, Jerry R. Mitchell, Snorri S. Thorgeirsson, James R. Gillette	34
16	THE EFFECT OF STARVATION ON THE KINETICS OF DRUG OXIDATION BY HEPATIC MICROSOMAL ENZYMES FROM MALE AND FEMALE RATS 1970 ·Journal of Pharmacology and Experimental Therapeutics ·Theodore E. Gram, Anthony M. Guarino, David H. Schroeder, Donald C. Davis, Reginald L. Reagan, James R. Gillette	42
17	Microsomes and drug oxidation breakdown → 1969 ·(unknown), James R. Gillette	290
18	DISPOSITION OF THALIDOMIDE IN RABBITS AND RATS 1968 ·Journal of Pharmacology and Experimental Therapeutics ·Herbert Schumacher, David A. Blake, James R. Gillette	42
19	Drug Interaction with Hepatic Microsomal Cytochrome 1966 ·Molecular Pharmacology ·H. Remmer, John B. Schenkman, R.W. Estabrook, Hènry A. Sasame, James R. Gillette, S. B. Narasimhulu, David Y. Cooper, Otto Rosenthal	285
20	Isolation from rat brain of a metabolic product, desmethylimipramine, that mediates the antidepressant activity of imipramine (Tofranil) 1961 ·Cellular and Molecular Life Sciences ·James R. Gillette, James V. Dingell, Fridolin Sulser, R. Kuntzman, B.B. Brodie	88

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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