James R. Gillette

18.1k total citations · 5 hit papers
184 papers, 14.8k citations indexed

About

James R. Gillette is a scholar working on Pharmacology, Molecular Biology and Oncology. According to data from OpenAlex, James R. Gillette has authored 184 papers receiving a total of 14.8k indexed citations (citations by other indexed papers that have themselves been cited), including 94 papers in Pharmacology, 46 papers in Molecular Biology and 29 papers in Oncology. Recurrent topics in James R. Gillette's work include Pharmacogenetics and Drug Metabolism (82 papers), Metabolism and Genetic Disorders (28 papers) and Drug Transport and Resistance Mechanisms (27 papers). James R. Gillette is often cited by papers focused on Pharmacogenetics and Drug Metabolism (82 papers), Metabolism and Genetic Disorders (28 papers) and Drug Transport and Resistance Mechanisms (27 papers). James R. Gillette collaborates with scholars based in United States, Sweden and Czechia. James R. Gillette's co-authors include David J. Jollow, Nicola Zampaglione, John R. Mitchell, B.B. Brodie, J.R. Mitchell, Hènry A. Sasame, William Z. Potter, Ryuichi Kato, Philippe L. Gigon and Theodore E. Gram and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

James R. Gillette

182 papers receiving 13.6k citations

Hit Papers

Bromobenzene-Induced Live... 1958 2026 1980 2003 1974 1973 1965 1958 1969 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Bromobenzene-Induced Liver Necrosis. Protective Role of Glutathione and Evidence for 3,4-Bromobenzene Oxide as the Hepatotoxic Metabolite
    1974 2.9k citations David J. Jollow, Nicola Zampaglione et al. profile →
  2. ACETAMINOPHEN-INDUCED HEPATIC NECROSIS. IV. PROTECTIVE ROLE OF GLUTATHIONE
    1973 1.5k citations J.R. Mitchell, David J. Jollow et al. Journal of Pharmacology and Experimental Therapeutics profile →
  3. EFFECT OF STARVATION ON NADPH-DEPENDENT ENZYMES IN LIVER MICROSOMES OF MALE AND FEMALE RATS
    1965 496 citations James R. Gillette et al. Journal of Pharmacology and Experimental Therapeutics profile →
  4. Enzymatic Metabolism of Drugs and other Foreign Compounds
    1958 368 citations James R. Gillette et al. profile →
  5. Microsomes and drug oxidation
    1969 290 citations James R. Gillette et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
James R. Gillette 7.8k 4.0k 2.7k 1.6k 1.4k 184 14.8k
Tetsuya Kamataki 7.9k 1.0× 5.5k 1.4× 4.0k 1.5× 1.4k 0.9× 742 0.5× 364 13.7k
David J. Jollow 7.2k 0.9× 2.7k 0.7× 2.4k 0.9× 1.1k 0.7× 1.4k 1.0× 94 12.7k
Ryo Sato 11.8k 1.5× 6.9k 1.7× 4.7k 1.8× 2.3k 1.4× 777 0.6× 125 17.3k
Ronald W. Estabrook 5.3k 0.7× 5.0k 1.2× 1.8k 0.7× 1.5k 0.9× 410 0.3× 135 10.7k
Minor J. Coon 12.4k 1.6× 10.8k 2.7× 5.2k 2.0× 3.2k 2.0× 911 0.6× 257 24.0k
Olavi Pelkonen 6.4k 0.8× 3.9k 1.0× 2.8k 1.0× 1.0k 0.6× 740 0.5× 291 13.2k
Thomas K. H. Chang 6.4k 0.8× 3.9k 1.0× 3.0k 1.1× 1.3k 0.8× 439 0.3× 222 12.1k
Harry V. Gelboin 11.0k 1.4× 6.6k 1.6× 4.6k 1.7× 2.5k 1.5× 877 0.6× 288 19.0k
Tsuneo Omura 13.3k 1.7× 11.1k 2.8× 5.4k 2.0× 2.6k 1.6× 1.0k 0.7× 176 23.7k
Neil Kaplowitz 9.2k 1.2× 8.4k 2.1× 4.4k 1.7× 3.7k 2.3× 877 0.6× 314 30.6k

Countries citing papers authored by James R. Gillette

Since Specialization
Citations

This map shows the geographic impact of James R. Gillette's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James R. Gillette with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James R. Gillette more than expected).

Fields of papers citing papers by James R. Gillette

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James R. Gillette. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James R. Gillette. The network helps show where James R. Gillette may publish in the future.

Co-authorship network of co-authors of James R. Gillette

This figure shows the co-authorship network connecting the top 25 collaborators of James R. Gillette. A scholar is included among the top collaborators of James R. Gillette based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James R. Gillette. James R. Gillette is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Gonzalez, Frank J., Tamihide Matsunaga, Kiyoshi Nagata, et al.. (1987). Debrisoquine 4-Hydroxylase: Characterization of a New P450 Gene Subfamily, Regulation, Chromosomal Mapping, and Molecular Analysis of the DA Rat Polymorphism. DNA. 6(2). 149–161. 124 indexed citations
2.
Monks, Terrence J., S S Lau, R. J. Highet, & James R. Gillette. (1985). Glutathione conjugates of 2-bromohydroquinone are nephrotoxic.. Drug Metabolism and Disposition. 13(5). 553–559. 106 indexed citations
3.
Gillette, James R.. (1982). The Problem of Chemically Reactive Metabolites. Drug Metabolism Reviews. 13(6). 941–961. 19 indexed citations
4.
Gillette, James R.. (1980). Pharmacokinetic Factors Governing the Steady‐State Concentrations of Foreign Chemicals and Their Metabolites. Novartis Foundation symposium. 76. 191–217. 5 indexed citations
5.
Hinson, Jack, Sidney D. Nelson, & James R. Gillette. (1979). Metabolism of [p-18O]-Phenacetin: The Mechanism of Activation of Phenacetin to Reactive Metabolites in Hamsters. Molecular Pharmacology. 15(2). 419–427. 33 indexed citations
6.
Dybing, Erik, Sidney D. Nelson, J.R. Mitchell, Hènry A. Sasame, & James R. Gillette. (1976). Oxidation of alpha-methyldopa and other catechols by cytochrome P-450-generated superoxide anion: possible mechanism of methyldopa hepatitis.. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich). 12(6). 911–20. 130 indexed citations
7.
Mitchell, J., Wayne R. Snodgrass, & James R. Gillette. (1976). The role of biotransformation in chemical-induced liver injury.. Environmental Health Perspectives. 15. 27–38. 59 indexed citations
8.
Zampaglione, Nicola, David J. Jollow, J.R. Mitchell, et al.. (1973). ROLE OF DETOXIFYING ENZYMES IN BROMOBENZENE-INDUCED LIVER NECROSIS. Journal of Pharmacology and Experimental Therapeutics. 187(1). 218–227. 174 indexed citations
9.
Sasame, Hènry A., Jerry R. Mitchell, Snorri S. Thorgeirsson, & James R. Gillette. (1973). RELATIONSHIP BETWEEN NADH AND NADPH OXIDATION DURING DRUG METABOLISM. Drug Metabolism and Disposition. 1(1). 150–155. 34 indexed citations
10.
Davis, Donald C., David H. Schroeder, Theodore E. Gram, Reginald L. Reagan, & James R. Gillette. (1971). A COMPARISON OF THE EFFECTS OF HALOTHANE AND CCl4 ON THE HEPATIC DRUG METABOLIZING SYSTEM. Journal of Pharmacology and Experimental Therapeutics. 177(3). 556–566. 21 indexed citations
11.
Gram, Theodore E., Anthony M. Guarino, David H. Schroeder, et al.. (1970). THE EFFECT OF STARVATION ON THE KINETICS OF DRUG OXIDATION BY HEPATIC MICROSOMAL ENZYMES FROM MALE AND FEMALE RATS. Journal of Pharmacology and Experimental Therapeutics. 175(1). 12–21. 42 indexed citations
12.
Gillette, James R., et al.. (1969). Microsomes and drug oxidation. 290 indexed citations breakdown →
13.
Guarino, Anthony M., et al.. (1969). ALTERATIONS IN KINETIC CONSTANTS FOR HEPATIC MICROSOMAL ANILINE HYDROXYLASE AND ETHYLMORPHINE N-DEMETHYLASE ASSOCIATED WITH PREGNANCY IN RATS. Journal of Pharmacology and Experimental Therapeutics. 168(2). 224–228. 49 indexed citations
14.
Guarino, Anthony M., Theodore E. Gram, Philippe L. Gigon, Frank E. Greene, & James R. Gillette. (1969). Changes in Michaelis and Spectral Constants for Aniline in Hepatic Microsomes from Phenobarbital-Treated Rats. Molecular Pharmacology. 5(2). 131–136. 56 indexed citations
15.
Stripp, Barry R., Frank E. Greene, & James R. Gillette. (1969). DISULFIRAM IMPAIRMENT OF DRUG METABOLISM BY RAT LIVER MICROSOMES. Journal of Pharmacology and Experimental Therapeutics. 170(2). 347–354. 54 indexed citations
16.
Gillette, James R., Jerome J. Kamm, & Hènry A. Sasame. (1968). Mechanism of p-Nitrobenzoate Reduction in Liver: The Possible Role of Cytochrome P-450 in Liver Microsomes. Molecular Pharmacology. 4(6). 541–548. 24 indexed citations
17.
Schumacher, Herbert, David A. Blake, & James R. Gillette. (1968). DISPOSITION OF THALIDOMIDE IN RABBITS AND RATS. Journal of Pharmacology and Experimental Therapeutics. 160(1). 201–211. 42 indexed citations
18.
Remmer, H., John B. Schenkman, R.W. Estabrook, et al.. (1966). Drug Interaction with Hepatic Microsomal Cytochrome. Molecular Pharmacology. 2(2). 187–190. 285 indexed citations
19.
Booth, Joan & James R. Gillette. (1962). THE EFFECT OF ANABOLIC STEROIDS ON DRUG METABOLISM BY MICROSOMAL ENZYMES IN RAT LIVER. Journal of Pharmacology and Experimental Therapeutics. 137(3). 374–379. 52 indexed citations
20.
Gillette, James R. & Jerome J. Kamm. (1960). THE ENZYMATIC FORMATION OF SULFOXIDES: THE OXIDATION OF CHLORPROMAZINE AND 4,4'-DIAMINODIPHENYL SULFIDE BY GUINEA PIG LIVER MICROSOMES. Journal of Pharmacology and Experimental Therapeutics. 130(3). 262–267. 44 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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