C. Roland Wolf

32.4k total citations · 3 hit papers
460 papers, 24.8k citations indexed

About

C. Roland Wolf is a scholar working on Molecular Biology, Pharmacology and Oncology. According to data from OpenAlex, C. Roland Wolf has authored 460 papers receiving a total of 24.8k indexed citations (citations by other indexed papers that have themselves been cited), including 245 papers in Molecular Biology, 239 papers in Pharmacology and 130 papers in Oncology. Recurrent topics in C. Roland Wolf's work include Pharmacogenetics and Drug Metabolism (236 papers), Glutathione Transferases and Polymorphisms (103 papers) and Drug Transport and Resistance Mechanisms (96 papers). C. Roland Wolf is often cited by papers focused on Pharmacogenetics and Drug Metabolism (236 papers), Glutathione Transferases and Polymorphisms (103 papers) and Drug Transport and Resistance Mechanisms (96 papers). C. Roland Wolf collaborates with scholars based in United Kingdom, United States and Germany. C. Roland Wolf's co-authors include Colin J. Henderson, John D. Hayes, Gillian Smith, Thomas Friedberg, Aileen McLaren, Mark J. I. Paine, Gordon C. K. Roberts, Xiu Jun Wang, Lesley M. Forrester and Lesley I. McLellan and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

C. Roland Wolf

456 papers receiving 24.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes.

2001 560 citations Michael McMahon, Colin J. Henderson et al. profile →
Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver

1994 511 citations M.D. Burke, C. Roland Wolf et al. profile →
Feedback control of AHR signalling regulates intestinal immunity

2017 403 citations Colin J. Henderson, C. Roland Wolf et al. profile →

Peers

Countries citing papers authored by C. Roland Wolf

Since Specialization

Citations

This map shows the geographic impact of C. Roland Wolf's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by C. Roland Wolf with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites C. Roland Wolf more than expected).

Fields of papers citing papers by C. Roland Wolf

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by C. Roland Wolf. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by C. Roland Wolf. The network helps show where C. Roland Wolf may publish in the future.

Co-authorship network of co-authors of C. Roland Wolf

This figure shows the co-authorship network connecting the top 25 collaborators of C. Roland Wolf. A scholar is included among the top collaborators of C. Roland Wolf based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with C. Roland Wolf. C. Roland Wolf is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals 2025 ·Archives of Toxicology ·Colin J. Henderson, Aileen McLaren, Andrew K. MacLeod, De‐Chen Lin, Amy Cameron, (unknown), Jonathan G. Moggs, Francisco Iñesta-Vaquera, John P. Thomson, Richard R. Meehan, Probir Chakravarty, Michael Schwarz, C. Roland Wolf	1
2	Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism 2024 ·Proceedings of the National Academy of Sciences ·Annette MacLeod, (unknown), (unknown), Frederick R. C. Simeons, Jennifer Riley, (unknown), (unknown), (unknown), (unknown), Érika G. Pinto, Liam Ferguson, (unknown), (unknown), Yoko Shishikura, Colin J. Henderson, David Cebrián, C. Roland Wolf, Kevin D. Read	9
3	Novel in vivo TDP-43 stress reporter models to accelerate drug development in ALS 2024 ·Open Biology ·(unknown), C. Roland Wolf, Christopher M. Henstridge, Francisco Iñesta-Vaquera	1
4	Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity 2020 ·Environmental Pollution ·Francisco Iñesta-Vaquera, Panida Navasumrit, Colin J. Henderson, (unknown), Tadashi Honda, Albena T. Dinkova‐Kostova, Mathuros Ruchirawat, C. Roland Wolf	11
5	Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice 2019 ·Drug Metabolism and Disposition ·Yury Kapelyukh, Colin J. Henderson, Nico Scheer, Anja Rode, C. Roland Wolf	38
6	Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion 2019 ·Life Science Alliance ·Antonio Vitobello, Juliane Perner, (unknown), Jiang Zhu, Alberto Del Río-Espínola, (unknown), (unknown), Valérie Dubost, (unknown), Ulrike Naumann, Arne Mueller, Karen Kapur, Mark L. Borowsky, Colin J. Henderson, C. Roland Wolf, Michael Schwarz, Jonathan G. Moggs, Rémi Terranova	9
7	Identification of Novel Pathways of Osimertinib Disposition and Potential Implications for the Outcome of Lung Cancer Therapy 2018 ·Clinical Cancer Research ·Annette MacLeod, De Lin, Jeffrey Huang, Lesley A. McLaughlin, Colin J. Henderson, C. Roland Wolf	25
8	Measuring in vivo responses to endogenous and exogenous oxidative stress using a novel haem oxygenase 1 reporter mouse 2017 ·The Journal of Physiology ·Michael McMahon, (unknown), (unknown), (unknown), Colin J. Henderson, C. Roland Wolf	18
9	Olaparib, Monotherapy or with Ionizing Radiation, Exacerbates DNA Damage in Normal Tissues: Insights from a New p21 Reporter Mouse 2016 ·Molecular Cancer Research ·Michael McMahon, (unknown), Colin J. Henderson, C. Roland Wolf	21
10	Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer 2016 ·Cancer Research ·John P. Thomson, Raffaele Ottaviano, (unknown), Harri Lempiäinen, Arne Müller, Rémi Terranova, Robert S. Illingworth, Shaun Webb, Alastair Kerr, Marcus J. Lyall, Amanda J. Drake, C. Roland Wolf, Jonathan G. Moggs, Michael Schwarz, Richard R. Meehan	69
11	Aryl hydrocarbon receptor is required for optimal B‐cell proliferation 2016 ·The EMBO Journal ·Matteo Villa, Manolis Gialitakis, Mauro Tolaini, Helena Ahlfors, Colin J. Henderson, C. Roland Wolf, Robert Brink, Brigitta Stockinger	74
12	Application of Mice Humanized for CYP2D6 to the Study of Tamoxifen Metabolism and Drug–Drug Interaction with Antidepressants 2016 ·Drug Metabolism and Disposition ·(unknown), Lesley A. McLaughlin, Colin J. Henderson, C. Roland Wolf	12
13	Activation Status of the Pregnane X Receptor Influences Vemurafenib Availability in Humanized Mouse Models 2015 ·Cancer Research ·(unknown), Lesley A. McLaughlin, Colin J. Henderson, C. Roland Wolf	19
14	In Vivo Regulation of Human Glutathione Transferase GSTP by Chemopreventive Agents 2014 ·Cancer Research ·Colin J. Henderson, Aileen McLaren, C. Roland Wolf	23
15	Conditional Expression of Human PPARδand a Dominant Negative Variant of hPPARδ In Vivo 2012 ·PPAR Research ·Larry G. Higgins, Wojciech G. Garbacz, Mattias C. U. Gustafsson, (unknown), Peter R. Ashby, C. Roland Wolf, (unknown)	5
16	Increased Skin Papilloma Formation in Mice Lacking Glutathione Transferase GSTP 2011 ·Cancer Research ·Colin J. Henderson, Kenneth J. Ritchie, Aileen McLaren, Probir Chakravarty, C. Roland Wolf	18
17	Peroxiredoxin Gene Expression Signatures in Liver Reflect Toxic Insult 2010 ·Assay and Drug Development Technologies ·Rachel Young, John D. Hayes, (unknown), C. Roland Wolf, Bruce Whitelaw	7
18	Generation of a Stable Antioxidant Response Element–Driven Reporter Gene Cell Line and Its Use to Show Redox-Dependent Activation of Nrf2 by Cancer Chemotherapeutic Agents 2006 ·Cancer Research ·Xiu Jun Wang, John D. Hayes, C. Roland Wolf	269
19	Environmental Pollutant and Potent Mutagen 3-Nitrobenzanthrone Forms DNA Adducts after Reduction by NAD(P)H:Quinone Oxidoreductase and Conjugation by Acetyltransferases and Sulfotransferases in Human Hepatic Cytosols 2005 ·Cancer Research ·Volker M. Arlt, Marie Stiborová, Colin J. Henderson, Martin R. Osborne, Christian A. Bieler, Eva Frei, Václav Martínek, Bruno Sopko, C. Roland Wolf, Heinz H. Schmeiser, David H. Phillips	109
20	Multiple forms of cytochrome P-450 related to forms induced marginally by phenobarbital. Differences in structure and in the metabolism of alkoxyresorufins 1986 ·Biochemical Journal ·C. Roland Wolf, (unknown), Franz Oesch, Richard T. Mayer, M.D. Burke	85

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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