Christopher A. Benetatos

2.9k total citations · 2 hit papers
18 papers, 2.1k citations indexed

About

Christopher A. Benetatos is a scholar working on Molecular Biology, Oncology and Immunology. According to data from OpenAlex, Christopher A. Benetatos has authored 18 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 6 papers in Oncology and 6 papers in Immunology. Recurrent topics in Christopher A. Benetatos's work include Cell death mechanisms and regulation (8 papers), Ubiquitin and proteasome pathways (6 papers) and interferon and immune responses (4 papers). Christopher A. Benetatos is often cited by papers focused on Cell death mechanisms and regulation (8 papers), Ubiquitin and proteasome pathways (6 papers) and interferon and immune responses (4 papers). Christopher A. Benetatos collaborates with scholars based in United States, Australia and Switzerland. Christopher A. Benetatos's co-authors include John Silke, Stephen M. Condon, Srinivas K. Chunduru, W. Wei‐Lynn Wong, James E. Vince, David L. Vaux, Nufail Khan, Mark A. McKinlay, Diep Chau and Robert Brink and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Nature Communications.

In The Last Decade

Christopher A. Benetatos

18 papers receiving 2.0k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

2007 879 citations James E. Vince, W. Wei‐Lynn Wong et al. Cell profile →
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

2015 510 citations Kate E. Lawlor, Nufail Khan et al. Nature Communications profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Christopher A. Benetatos United States	13	1.6k	823	482	364	254	18	2.1k
Xuefeng Wu United States	25	1.2k 0.7×	953 1.2×	684 1.4×	445 1.2×	268 1.1×	42	2.0k
Junming Yie United States	16	1.7k 1.1×	873 1.1×	467 1.0×	460 1.3×	208 0.8×	21	2.5k
Soizic Daniel United States	24	684 0.4×	619 0.8×	296 0.6×	165 0.5×	161 0.6×	36	1.4k
Hannah Nguyen Canada	18	1.1k 0.7×	1.3k 1.5×	414 0.9×	1.1k 3.0×	242 1.0×	22	2.5k
C L Verweij Netherlands	25	757 0.5×	1.3k 1.6×	540 1.1×	456 1.3×	159 0.6×	33	2.9k
Robin Humphreys United States	29	1.5k 0.9×	461 0.6×	367 0.8×	903 2.5×	188 0.7×	55	2.2k
Guanhua Song China	19	829 0.5×	516 0.6×	386 0.8×	284 0.8×	139 0.5×	43	1.4k
Xin‐Yuan Fu United States	19	1.6k 1.0×	1.5k 1.8×	540 1.1×	1.8k 4.8×	177 0.7×	34	3.2k
Roshan J. Thapa United States	15	1.2k 0.8×	885 1.1×	228 0.5×	262 0.7×	290 1.1×	19	1.7k
Keishi Fujiwara Japan	21	983 0.6×	316 0.4×	248 0.5×	319 0.9×	840 3.3×	38	2.0k

Countries citing papers authored by Christopher A. Benetatos

Since Specialization

Citations

This map shows the geographic impact of Christopher A. Benetatos's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher A. Benetatos with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher A. Benetatos more than expected).

Fields of papers citing papers by Christopher A. Benetatos

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher A. Benetatos. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher A. Benetatos. The network helps show where Christopher A. Benetatos may publish in the future.

Co-authorship network of co-authors of Christopher A. Benetatos

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher A. Benetatos. A scholar is included among the top collaborators of Christopher A. Benetatos based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher A. Benetatos. Christopher A. Benetatos is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

Tanzer, Maria C., Nufail Khan, James Rickard, et al.. (2017). Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways. Cell Death and Differentiation. 24(3). 481–491. 38 indexed citations

Lawlor, Kate E., Nufail Khan, Motti Gerlic, et al.. (2015). RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL. Nature Communications. 6(1). 6282–6282. 510 indexed citations breakdown →

Kapoor, Gurpreet S., Christopher A. Benetatos, Yasuhiro Mitsuuchi, et al.. (2014). Abstract 2278: The SMAC-mimetic birinapant regulates autocrine TNF production by caspase-8:RIPK1 complex via p38MAPK pathway. Cancer Research. 74(19_Supplement). 2278–2278. 1 indexed citations

Krepler, Clemens, Srinivas K. Chunduru, Molly B. Halloran, et al.. (2013). The Novel SMAC Mimetic Birinapant Exhibits Potent Activity against Human Melanoma Cells. Clinical Cancer Research. 19(7). 1784–1794. 79 indexed citations

Kapoor, Gurpreet S., Brian Geier, Eric M. Neiman, et al.. (2013). Abstract 599: Potential biomarkers of Smac mimetic tumor sensitivity: inhibitor of apoptosis protein DNA copy number.. Cancer Research. 73(8_Supplement). 599–599. 1 indexed citations

Mitsuuchi, Yasuhiro, Stephen M. Condon, Eric M. Neiman, et al.. (2013). Abstract 3333: Birinapant, a novel bivalent Smac mimetic drug, is superior to monovalent Smac mimetics in inhibition of NF-kB by targeting TRAF2-bound cIAP1 and cIAP2.. Cancer Research. 73(8_Supplement). 3333–3333. 1 indexed citations

Darding, Maurice, Rebecca Feltham, Tencho Tenev, et al.. (2011). Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2. Cell Death and Differentiation. 18(8). 1376–1386. 81 indexed citations

Jackson, Randy W., Matthew G. LaPorte, Torsten Herbertz, et al.. (2011). The discovery and structure–activity relationships of pyrano[3,4-b]indole-based inhibitors of hepatitis C virus NS5B polymerase. Bioorganic & Medicinal Chemistry Letters. 21(11). 3227–3231. 17 indexed citations

Graham, Martin A., Jennifer Burns, Srinivas K. Chunduru, et al.. (2011). Abstract A25: Phase 1 PK/PD analysis of the Smac-mimetic TL32711 demonstrates potent and sustained cIAP1 suppression in patient PBMCs and tumor biopsies.. Molecular Cancer Therapeutics. 10(11_Supplement). A25–A25. 5 indexed citations

10.

LaPorte, Matthew G., Charles W. Blackledge, Lara K. Leister, et al.. (2010). The discovery and structure–activity relationships of pyrano[3,4-b]indole based inhibitors of hepatitis C virus NS5B polymerase. Bioorganic & Medicinal Chemistry Letters. 20(9). 2968–2973. 33 indexed citations

11.

Griffith, Thomas S., Tamara A. Kucaba, Michael A. O’Donnell, et al.. (2010). Sensitization of human bladder tumor cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis with a small molecule IAP antagonist. APOPTOSIS. 16(1). 13–26. 25 indexed citations

12.

Vince, James E., Diep Chau, Bernard A. Callus, et al.. (2008). TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα. The Journal of Cell Biology. 182(1). 171–184. 209 indexed citations

13.

Vince, James E., Diep Chau, Bernard A. Callus, et al.. (2008). TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα. The Journal of Experimental Medicine. 205(8). i18–i18. 1 indexed citations

14.

Vince, James E., W. Wei‐Lynn Wong, Nufail Khan, et al.. (2007). IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis. Cell. 131(4). 682–693. 879 indexed citations breakdown →

15.

Yang, Guang, Daniel C. Pevear, Marc S. Collett, et al.. (2004). Newly Synthesized Hepatitis C Virus Replicon RNA Is Protected from Nuclease Activity by a Protease-Sensitive Factor(s). Journal of Virology. 78(18). 10202–10205. 15 indexed citations

16.

Baginski, Scott G., Daniel C. Pevear, Christopher A. Benetatos, et al.. (2000). Mechanism of action of a pestivirus antiviral compound. Proceedings of the National Academy of Sciences. 97(14). 7981–7986. 89 indexed citations

17.

Ranganathan, Sulabha, et al.. (1998). Cloning and sequencing of human βIII-tubulin cDNA: induction of βIII isotype in human prostate carcinoma cells by acute exposure to antimicrotubule agents. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1395(2). 237–245. 42 indexed citations

18.

Ranganathan, Sulabha, Hernando Salazar, Christopher A. Benetatos, & Gary R. Hudes. (1997). Immunohistochemical analysis of β-tubulin isotypes in human prostate carcinoma and benign prostatic hypertrophy. The Prostate. 30(4). 263–268. 36 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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