Srinivas K. Chunduru

3.3k citations

42 papers · 2.3k indexed · 1 hit paper · h-index 18

Co-authors: Mark A. McKinlay Christopher A. Benetatos Stephen M. Condon John Silke David L. Vaux James E. Vince W. Wei‐Lynn Wong Diep Chau
Topics: Cell death mechanisms and regulation (11 papers)Ubiquitin and proteasome pathways (7 papers)Hepatitis B Virus Studies (7 papers)
Cited by: Cancer Research Immunology Hepatology
Journals: Cell Proceedings of the National Academy of Sciences Journal of Biological Chemistry
Partner nations: United States Australia Switzerland

In The Last Decade

Srinivas K. Chunduru

42 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

2007 879 citations James E. Vince, W. Wei‐Lynn Wong et al. Cell profile →

Peers

Countries citing papers authored by Srinivas K. Chunduru

Since Specialization

Citations

This map shows the geographic impact of Srinivas K. Chunduru's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Srinivas K. Chunduru with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Srinivas K. Chunduru more than expected).

Fields of papers citing papers by Srinivas K. Chunduru

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Srinivas K. Chunduru. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Srinivas K. Chunduru. The network helps show where Srinivas K. Chunduru may publish in the future.

Co-authorship network of co-authors of Srinivas K. Chunduru

This figure shows the co-authorship network connecting the top 25 collaborators of Srinivas K. Chunduru. A scholar is included among the top collaborators of Srinivas K. Chunduru based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Srinivas K. Chunduru. Srinivas K. Chunduru is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Phase III randomized trial evaluating tilsotolimod in combination with ipilimumab versus ipilimumab alone in patients with advanced refractory melanoma (ILLUMINATE 301). 2024 ·Journal of Clinical Oncology ·Adi Diab,Paolo A. Ascierto,Reham Abdel‐Wahab,Michele Maio,Sylvie Négrier,Laurent Mortier,Stéphane Dalle,Ivana Krajsová,Luis de la Cruz‐Merino,M.‐T. Leccia,Michele Guida,Célèste Lebbé,Jean‐Jacques Grob,Marcus O. Butler,Gino K. In,Srinivas K. Chunduru,(unknown),Caroline Robert	2
2	1031P Tilsotolimod engages the TLR9 pathway to promote antigen presentation and type I IFN signaling in solid tumours 2020 ·Annals of Oncology ·Hani M. Babiker,Erkut Borazanci,Vivek Subbiah,Alain P. Algazi,Jacob Schachter,Michal Lotem,Daniel Hendler,(unknown),Hans Minderman,Cara Haymaker,Chantale Bernatchez,Ravi Murthy,(unknown),Nadia Caplan,Gregory Woodhead,(unknown),Srinivas K. Chunduru,Peter M. Anderson,Adi Diab,Igor Puzanov	2
3	A phase 2, double-blinded, placebo-controlled trial of toll-like receptor 7/8/9 antagonist, IMO-8400, in dermatomyositis 2020 ·Journal of the American Academy of Dermatology ·Yoo Jung Kim,Elena Schiopu,Katalin Dankó,Tahseen Mozaffar,Srinivas K. Chunduru,(unknown),Namita Goyal,(unknown),David Fiorentino,Kavita Y. Sarin	13
4	LB1115 A double-blind, placebo-controlled, phase 2 trial of IMO-8400, a novel toll-like receptor 7/8/9 antagonist, in dermatomyositis 2019 ·Journal of Investigative Dermatology ·(unknown),Elena Schiopu,Tahseen Mozaffar,Srinivas K. Chunduru,(unknown),Namita Goyal,Kavita Y. Sarin,David Fiorentino	2
5	Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways 2017 ·Cell Death and Differentiation ·Maria C. Tanzer,Nufail Khan,James Rickard,Nima Etemadi,Najoua Lalaoui,Sukhdeep K. Spall,Joanne M. Hildebrand,David Segal,Maria Miasari,Diep Chau,W. Wei‐Lynn Wong,Mark A. McKinlay,Srinivas K. Chunduru,Christopher A. Benetatos,Stephen M. Condon,James E. Vince,Marco J. Herold,John Silke	38
6	Abstract 2278: The SMAC-mimetic birinapant regulates autocrine TNF production by caspase-8:RIPK1 complex via p38MAPK pathway 2014 ·Cancer Research ·Gurpreet S. Kapoor,Christopher A. Benetatos,Yasuhiro Mitsuuchi,Eric M. Neiman,Guangyao Yu,Mark A. McKinlay,Jennifer M. Burns,John Silke,Stephen M. Condon,Srinivas K. Chunduru	1
7	The Novel SMAC Mimetic Birinapant Exhibits Potent Activity against Human Melanoma Cells 2013 ·Clinical Cancer Research ·Clemens Krepler,Srinivas K. Chunduru,Molly B. Halloran,He Xu,Min Xiao,Adina Vultur,Jessie Villanueva,Yasuhiro Mitsuuchi,Eric M. Neiman,Christopher A. Benetatos,Katherine L. Nathanson,Ravi K. Amaravadi,Hubert Pehamberger,Mark A. McKinlay,Meenhard Herlyn	79
8	Smac Mimetics Activate the E3 Ligase Activity of cIAP1 Protein by Promoting RING Domain Dimerization 2011 ·Journal of Biological Chemistry ·Rebecca Feltham,(unknown),Rhesa Budhidarmo,Peter D. Mace,Sarah Shirley,Stephen M. Condon,Srinivas K. Chunduru,Mark A. McKinlay,David L. Vaux,John Silke,Catherine L. Day	120
9	Abstract LB-406: Phase 1 study of the Smac mimetic TL32711 in adult subjects with advanced solid tumors and lymphoma to evaluate safety, pharmacokinetics, pharmacodynamics, and antitumor activity 2011 ·Cancer Research ·Ravi K. Amaravadi,Russell J. Schilder,Grace K. Dy,Wen Wang,Gerald J. Fetterly,David Weng,Martin A. Graham,Jennifer Burns,Srinivas K. Chunduru,Stephen M. Condon,Mark A. McKinlay,Alex A. Adjei	17
10	The discovery and structure–activity relationships of pyrano[3,4-b]indole-based inhibitors of hepatitis C virus NS5B polymerase 2011 ·Bioorganic & Medicinal Chemistry Letters ·Randy W. Jackson,Matthew G. LaPorte,Torsten Herbertz,(unknown),(unknown),Susan R. Rippin,Ravi M. Patel,Srinivas K. Chunduru,Christopher A. Benetatos,Dorothy C. Young,Christopher J. Burns,Stephen M. Condon	17
11	The discovery and structure–activity relationships of pyrano[3,4-b]indole based inhibitors of hepatitis C virus NS5B polymerase 2010 ·Bioorganic & Medicinal Chemistry Letters ·Matthew G. LaPorte,(unknown),(unknown),Charles W. Blackledge,Lara K. Leister,(unknown),(unknown),Dorothy C. Young,Srinivas K. Chunduru,Christopher A. Benetatos,Gerry Rhodes,Ariamala Gopalsamy,Torsten Herbertz,Christopher J. Burns,Stephen M. Condon	33
12	TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα 2008 ·The Journal of Cell Biology ·James E. Vince,Diep Chau,Bernard A. Callus,W. Wei‐Lynn Wong,Christine J. Hawkins,Pascal Schneider,Mark A. McKinlay,Christopher A. Benetatos,Stephen M. Condon,Srinivas K. Chunduru,George C. Yeoh,Robert Brink,David L. Vaux,John Silke	209
13	IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosisbreakdown → 2007 ·Cell ·James E. Vince,W. Wei‐Lynn Wong,Nufail Khan,Rebecca Feltham,Diep Chau,Afsar U. Ahmed,Christopher A. Benetatos,Srinivas K. Chunduru,Stephen M. Condon,Mark A. McKinlay,Robert Brink,Martin Leverkus,Vinay Tergaonkar,Pascal Schneider,Bernard A. Callus,Frank Köentgen,David L. Vaux,John Silke	879
14	Tetrahydrobenzothiophene inhibitors of hepatitis C virus NS5B polymerase 2005 ·Bioorganic & Medicinal Chemistry Letters ·Matthew G. LaPorte,(unknown),Lara K. Leister,(unknown),(unknown),Charles Faust,(unknown),(unknown),Theodore J. Nitz,Srinivas K. Chunduru,Dorothy C. Young,Christine Burns	8
15	Methotrexate-resistant Variants of Human Dihydrofolate Reductase with Substitutions of Leucine 22 1995 ·Journal of Biological Chemistry ·William S. Lewis,Vivian Cody,Nikolai Galitsky,Joseph R. Luft,Walter Pangborn,Srinivas K. Chunduru,H. Trent Spencer,James R. Appleman,Raymond L. Blakley	124
16	Kinetic Investigation of Methotrexate Resistant Human Dihydrofolate Reductase (hDHFR) Mutants at PHE31 1993 ·Advances in experimental medicine and biology ·Srinivas K. Chunduru,James R. Appleman,Raymond L. Blakley	2
17	Activity of Human DNA Polymerases α and β with 2-Chloro-2′-deoxyadenosine 5′-Triphosphate as a Substrate and Quantitative Effects of Incorporation on Chain Extension 1993 ·Archives of Biochemistry and Biophysics ·Srinivas K. Chunduru,James R. Appleman,Raymond L. Blakley	20
18	Mutations of Human Dihydrofolate Reductase Causing Decreased Inhibition by Methotrexate 1993 ·Advances in experimental medicine and biology ·Raymond L. Blakley,James R. Appleman,Srinivas K. Chunduru,Takayuki Nakano,William S. Lewis,Susan E. Harris	2
19	The pH dependence of the kinetic parameters of ketol acid reductoisomerase indicates a proton shuttle mechanism for alkyl migration 1992 ·Archives of Biochemistry and Biophysics ·Gregory T. Mrachko,Srinivas K. Chunduru,(unknown)	15
20	Mechanism of ketol acid reductoisomerase. Steady-state analysis and metal ion requirement 1989 ·Biochemistry ·Srinivas K. Chunduru,Gregory T. Mrachko,(unknown)	70

About Srinivas K. Chunduru

Srinivas K. Chunduru is a scholar working on Hepatology, Immunology and Cancer Research, having authored 42 papers that have together received 2.3k indexed citations. Recurring topics across this work include Cell death mechanisms and regulation (11 papers), Ubiquitin and proteasome pathways (7 papers) and Hepatitis B Virus Studies (7 papers). The work is most often cited by research in Cancer Research (460 citations), Immunology (640 citations) and Hepatology (190 citations). Srinivas K. Chunduru has collaborated with scholars based in United States, Australia and Switzerland. Frequent co-authors include Mark A. McKinlay, Christopher A. Benetatos, Stephen M. Condon, John Silke, David L. Vaux, James E. Vince, W. Wei‐Lynn Wong, Diep Chau, Pascal Schneider and Bernard A. Callus. Their work appears in journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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