Maarten van Lohuizen

25.4k total citations · 7 hit papers
143 papers, 20.4k citations indexed

About

Maarten van Lohuizen is a scholar working on Molecular Biology, Genetics and Oncology. According to data from OpenAlex, Maarten van Lohuizen has authored 143 papers receiving a total of 20.4k indexed citations (citations by other indexed papers that have themselves been cited), including 135 papers in Molecular Biology, 25 papers in Genetics and 20 papers in Oncology. Recurrent topics in Maarten van Lohuizen's work include Epigenetics and DNA Methylation (79 papers), Genomics and Chromatin Dynamics (42 papers) and Cancer-related gene regulation (32 papers). Maarten van Lohuizen is often cited by papers focused on Epigenetics and DNA Methylation (79 papers), Genomics and Chromatin Dynamics (42 papers) and Cancer-related gene regulation (32 papers). Maarten van Lohuizen collaborates with scholars based in Netherlands, United States and United Kingdom. Maarten van Lohuizen's co-authors include Jacqueline J.L. Jacobs, Anton Berns, Anke Sparmann, Anders H. Lund, Silvia Marino, Sophia W.M. Bruggeman, Ronald A. DePinho, Jan Willem Voncken, Ellen Wientjens and Ellen Tanger and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Maarten van Lohuizen

143 papers receiving 20.2k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

1999 1.3k citations Jacqueline J.L. Jacobs, Silvia Marino et al. profile →
Polycomb silencers control cell fate, development and cancer

2006 1.0k citations Maarten van Lohuizen et al. profile →
Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF

1999 906 citations Jacqueline J.L. Jacobs, Anton Berns et al. Genes & Development profile →
Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

2010 763 citations Sophia W.M. Bruggeman, Maarten van Lohuizen et al. Molecular Cell profile →
Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene.

1994 644 citations Maarten van Lohuizen et al. Genes & Development profile →
Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging

1991 640 citations Maarten van Lohuizen, Anton Berns et al. profile →
Stem Cells and Cancer

2004 595 citations Sophia W.M. Bruggeman, Maarten van Lohuizen et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Maarten van Lohuizen Netherlands	73	17.4k	4.0k	2.6k	2.4k	1.4k	143	20.4k
John G. Doench United States	51	15.7k 0.9×	3.2k 0.8×	2.1k 0.8×	3.8k 1.6×	2.6k 1.9×	145	20.0k
Martin Eilers Germany	77	16.1k 0.9×	6.9k 1.7×	1.7k 0.7×	3.1k 1.3×	2.2k 1.6×	193	20.6k
Robert Benezra United States	63	14.6k 0.8×	5.2k 1.3×	1.7k 0.7×	3.8k 1.6×	1.9k 1.4×	118	19.3k
Peggy Farnham United States	77	17.5k 1.0×	3.6k 0.9×	3.7k 1.4×	4.7k 2.0×	1.8k 1.3×	184	21.1k
Peter Marynen Belgium	67	6.8k 0.4×	2.3k 0.6×	3.1k 1.2×	2.0k 0.9×	2.0k 1.5×	289	14.9k
David A. Largaespada United States	57	7.8k 0.4×	1.9k 0.5×	2.6k 1.0×	1.6k 0.7×	2.1k 1.5×	213	11.8k
Ad Geurts van Kessel Netherlands	63	8.0k 0.5×	2.0k 0.5×	4.8k 1.8×	1.9k 0.8×	1.2k 0.9×	256	15.6k
Thomas W. Glover United States	60	10.3k 0.6×	3.6k 0.9×	4.5k 1.7×	1.8k 0.8×	352 0.3×	159	15.8k
Frank Speleman Belgium	60	7.9k 0.5×	2.2k 0.6×	2.1k 0.8×	4.6k 1.9×	732 0.5×	285	12.9k
Toru Nakano Japan	68	12.9k 0.7×	1.8k 0.4×	2.7k 1.0×	1.8k 0.8×	4.6k 3.3×	208	18.9k

Countries citing papers authored by Maarten van Lohuizen

Since Specialization

Citations

This map shows the geographic impact of Maarten van Lohuizen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Maarten van Lohuizen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Maarten van Lohuizen more than expected).

Fields of papers citing papers by Maarten van Lohuizen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Maarten van Lohuizen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Maarten van Lohuizen. The network helps show where Maarten van Lohuizen may publish in the future.

Co-authorship network of co-authors of Maarten van Lohuizen

This figure shows the co-authorship network connecting the top 25 collaborators of Maarten van Lohuizen. A scholar is included among the top collaborators of Maarten van Lohuizen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Maarten van Lohuizen. Maarten van Lohuizen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Hulsman, Danielle, et al.. (2024). Combination of EZH2 and ATM inhibition in BAP1-deficient mesothelioma. British Journal of Cancer. 130(11). 1855–1865. 6 indexed citations

Badhai, Jitendra, Gaurav Kumar Pandey, Ji‐Ying Song, et al.. (2023). Combined Inhibition of EZH2 and FGFR is Synergistic in BAP1-deficient Malignant Mesothelioma. Cancer Research Communications. 4(1). 18–27. 5 indexed citations

Berk, Paul van den, Cesare Lancini, Michela Serresi, et al.. (2020). USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells. Cell Reports. 33(13). 108533–108533. 17 indexed citations

Kato, Yuko, Satoru Miyagi, Eriko Nitta, et al.. (2019). Bmi1 restricts the adipogenic differentiation of bone marrow stromal cells to maintain the integrity of the hematopoietic stem cell niche. Experimental Hematology. 76. 24–37. 9 indexed citations

Koppens, Martijn, Ellen Tanger, Karim Nacerddine, et al.. (2016). A new transgenic mouse model for conditional overexpression of the Polycomb Group protein EZH2. Transgenic Research. 26(2). 187–196. 7 indexed citations

Koppens, Martijn, Gergana Bounova, Paulien Cornelissen‐Steijger, et al.. (2016). Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition. Oncotarget. 7(43). 69816–69828. 21 indexed citations

Pósfai, Eszter, Vincent Brochard, Juliette Salvaing, et al.. (2012). Polycomb function during oogenesis is required for mouse embryonic development. Genes & Development. 26(9). 920–932. 107 indexed citations

Smith, Lan‐Lan, Jenny Yeung, Bernd B. Zeisig, et al.. (2011). Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells. Cell stem cell. 8(6). 649–662. 89 indexed citations

Vries, Nienke A. de, Sophia W.M. Bruggeman, Danielle Hulsman, et al.. (2010). Rapid and Robust Transgenic High-Grade Glioma Mouse Models for Therapy Intervention Studies. Clinical Cancer Research. 16(13). 3431–3441. 40 indexed citations

10.

Kool, Jaap, Anthony G. Uren, Jeroen de Ridder, et al.. (2010). Novel Candidate Cancer Genes Identified by a Large-Scale Cross-Species Comparative Oncogenomics Approach. Cancer Research. 70(3). 883–895. 34 indexed citations

11.

Kool, Jaap, Anthony G. Uren, Daoud Sie, et al.. (2010). Insertional Mutagenesis in Mice Deficient for p15Ink4b, p16Ink4a, p21Cip1 , and p27Kip1 Reveals Cancer Gene Interactions and Correlations with Tumor Phenotypes. Cancer Research. 70(2). 520–531. 25 indexed citations

12.

Uren, Anthony G., Harald Mikkers, Jaap Kool, et al.. (2009). A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites. Nature Protocols. 4(5). 789–798. 129 indexed citations

13.

Miyazaki, Masaki, Kazuko Miyazaki, Manami Itoi, et al.. (2008). Thymocyte Proliferation Induced by Pre-T Cell Receptor Signaling Is Maintained through Polycomb Gene Product Bmi-1-Mediated Cdkn2a Repression. Immunity. 28(2). 231–245. 55 indexed citations

14.

Crippa, Sylvain V., Ellen Tanger, Daniel F. Schorderet, et al.. (2007). Bmi1 Loss Delays Photoreceptor Degeneration in Rd1 Mice. Advances in experimental medicine and biology. 572. 209–215. 3 indexed citations

15.

Hosokawa, Hiroyuki, Motoko Y. Kimura, Ryo Shinnakasu, et al.. (2006). Regulation of Th2 Cell Development by Polycomb Group Gene bmi-1 through the Stabilization of GATA3. The Journal of Immunology. 177(11). 7656–7664. 47 indexed citations

16.

Bruggeman, Sophia W.M., Jacqueline J.L. Jacobs, Ellen Tanger, et al.. (2005). Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice. Genes & Development. 19(12). 1438–1443. 260 indexed citations

17.

Smith, Kevin S., Sumit K. Chanda, Douglas T. Ross, et al.. (2003). Bmi-1 Regulation of INK4A-ARF Is a Downstream Requirement for Transformation of Hematopoietic Progenitors by E2a-Pbx1. Molecular Cell. 12(2). 393–400. 75 indexed citations

18.

Jacobs, Jacqueline J.L. & Maarten van Lohuizen. (2002). Polycomb repression: from cellular memory to cellular proliferation and cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1602(2). 151–161. 178 indexed citations

19.

Itahana, Koji, Ying Zou, Yoko Itahana, et al.. (2002). Control of the Replicative Life Span of Human Fibroblasts by p16 and the Polycomb Protein Bmi-1. Molecular and Cellular Biology. 23(1). 389–401. 340 indexed citations

20.

Nusse, Roel, et al.. (1985). Retroviral insertional mutagenesis in murine mammary cancer. Proceedings of the Royal Society of London. Series B, Biological sciences. 226(1242). 3–13. 14 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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