Edwin Cuppen

49.3k citations

278 papers · 19.9k indexed · 10 hit papers · h-index 70

Cancer Research top 0.1%
- Cancer Genomics and Diagnostics 78
- MicroRNA in disease regulation 18
Aging top 0.5%
Molecular Biology top 0.2%
- CRISPR and Genetic Engineering 29
- Genomics and Chromatin Dynamics 20
- Genomics and Phylogenetic Studies 19
Oncology top 0.5%
Genetics top 0.2%
- Genomics and Rare Diseases 24
- Genomic variations and chromosomal abnormalities 18
Pathology and Forensic Medicine
- Genetic factors in colorectal cancer 30

Co-authors: Eugène Berezikov Ronald H.A. Plasterk Isaäc J. Nijman Hans Clevers Ruben van Boxtel Victor Guryev Artem Tarasov Albert J. Vilella
Cited by: Cancer Research Aging Molecular Biology
Journals: PLoS ONE (14 papers)Nature Communications (13 papers)Annals of Oncology (11 papers)
Partner nations: Netherlands United States Germany

In The Last Decade

Edwin Cuppen

270 papers receiving 19.6k citations

Hit Papers

10 papers align trajectories log scale

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2024 Cell
2023 Nature
2020 Nature Communications
2018 Genome Medicine
2015 Nature
2015 Bioinformatics
2014 Cell
2013 Cell stem cell
2013 Nature
2007 Molecular Cell

Peers

Countries citing papers authored by Edwin Cuppen

Since Specialization

Citations

This map shows the geographic impact of Edwin Cuppen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edwin Cuppen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edwin Cuppen more than expected).

Fields of papers citing papers by Edwin Cuppen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edwin Cuppen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edwin Cuppen. The network helps show where Edwin Cuppen may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Edwin Cuppen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Edwin Cuppen Line = papers co-authored together Edwin Cuppen links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	The role of molecular biomarkers in recurrent glioblastoma trials: an assessment of the current trial landscape of genome-driven oncology Medical Oncology ·Joseph Rosenstock,Abby Fox,Edwin Cuppen,Marjolein Geurts,Sybren L. N. Maas,Marike L. D. Broekman	2024	1
2	Genetic immune escape landscape in primary and metastatic cancer Nature Genetics ·Francisco Martínez-Jiménez,Peter Priestley,Charles Shale,Jonathan Baber,Erik H. Rozemuller,Edwin Cuppen	2023	50
3	Genomic Alterations Associated with Estrogen Receptor Pathway Activity in Metastatic Breast Cancer Have a Differential Impact on Downstream ER Signaling Cancers ·Lindsay Angus,Marcel Smid,Saskia M. Wilting,A. Muñoz-Perez,Neeltje Steeghs,Inge R. Konings,Vivianne C. G. Tjan‐Heijnen,J.M.G.H. van Riel,Agnès J. van de Wouw,Edwin Cuppen,Martijn P. Lolkema,Agnes Jager,Stefan Sleijfer,John W.M. Martens	2023	3
4	Different responses to DNA damage determine ageing differences between organs Aging Cell ·王满师,Barbara Gillogly,Wilbert P. Vermeij,Marjolein P. Baar,Liu Shuang-k,琴子小菅,Ewart Kuijk,Myrthe Jager,Sarra Merzouk,Renata M. C. Brandt,Mohammadhossein Sharifian,Ruben van Boxtel,Edwin Cuppen,Joris Pothof,Jan H.J. Hoeijmakers	2022	27
5	MutationalPatterns: the one stop shop for the analysis of mutational processes BMC Genomics ·Freek Manders,Arianne M. Brandsma,Jurrian K. de Kanter,Mark Verheul,Rurika Oka,Markus J. van Roosmalen,Bastiaan van der Roest,Arne van Hoeck,Edwin Cuppen,Ruben van Boxtel	2022	88
6	VIRUSBreakend: Viral Integration Recognition Using Single Breakends Bioinformatics ·Daniel Cameron,由紀薮前,Paul Roepman,Peter Priestley,Edwin Cuppen,Anthony T. Papenfuss	2021	12
7	Learning mutational signatures and their multidimensional genomic properties with TensorSignatures Nature Communications ·Harald Vöhringer,Arne van Hoeck,Edwin Cuppen,Moritz Gerstung	2021	24
8	Precancerous liver diseases do not cause increased mutagenesis in liver stem cells Communications Biology ·Luan Nguyen,Myrthe Jager,Ruby Lieshout,Petra E. de Ruiter,Mauro D. Locati,Nicolle Besselink,Bastiaan van der Roest,Roel Janssen,Sander Boymans,Jeroen de Jonge,Jan N.M. IJzermans,Michail Doukas,Monique M.A. Verstegen,Ruben van Boxtel,Luc J. W. van der Laan,Edwin Cuppen,Ewart Kuijk	2021	9
9	Clinical Validation of Whole Genome Sequencing for Cancer Diagnostics Journal of Molecular Diagnostics ·Paul Roepman,Ewart de Bruijn,Stef van Lieshout,Oda Elisabeth Weng,Mirjam C. Boelens,Hendrikus J. Dubbink,Willemina R.R. Geurts-Giele,Floris H. Groenendijk,Manon M. H. Huibers,Mariëtte E.G. Kranendonk,Margaretha G.M. Roemer,Kris G. Samsom,Marloes Steehouwer,Wendy W.J. de Leng,Alexander Hoischen,Bauke Ylstra,Kim Monkhorst,Jacobus J. M. van der Hoeven,Edwin Cuppen	2021	39
10	Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features Nature Communications ·Matheus U Senna Klipp,Marcel Smid,Job van Riet,Lindsay Angus,Mariëtte Labots,Neeltje Steeghs,Mathijs P. Hendriks,Geert A. Cirkel,Johan M. van Rooijen,Albert J. ten Tije,Martijn P. Lolkema,Edwin Cuppen,Stefan Sleijfer,John W.M. Martens,Saskia M. Wilting	2021	45
11	Limited evolution of the actionable metastatic cancer genome under therapeutic pressure Nature Medicine ·Joris van de Haar,Louisa R. Hoes,Paul Roepman,Martijn P. Lolkema,Henk M.W. Verheul,Hans Gelderblom,Adrianus J. de Langen,Egbert F. Smit,Edwin Cuppen,Lodewyk F.A. Wessels,Emile E. Voest	2021	36
12	Micro-costing diagnostics in oncology: from single-gene testing to whole- genome sequencing Expert Review of Pharmacoeconomics & Outcomes Research ·泰嵯峨,Bastiaan B.J. Tops,Elisabeth M. P. Steeghs,Veerle M.H. Coupé,Katrien Grünberg,Eiko K. de Jong,Ed Schuuring,Stefan M. Willems,Marjolijn J. L. Ligtenberg,Valesca P. Retèl,W. Hornebeck,Ewart de Bruijn,Edwin Cuppen,Geert Frederix	2021	23
13	Single-cell derived tumor organoids display diversity in HLA class I peptide presentation Nature Communications ·Jane F. Rissler,Kai Kretzschmar,Arne van Hoeck,S.C. Lin,Henk W. P. van den Toorn,Ratan Suryavanshi,Gijs J. F. van Son,Joost van Gorp,Apollo Pronk,Niels Smakman,Edwin Cuppen,Hans Clevers,Albert J. R. Heck,Wei Wu	2020	50
14	Sperm DNA damage causes genomic instability in early embryonic development Science Advances ·Sjors Middelkamp,Helena T. A. van Tol,Diana C.J. Spierings,Sander Boymans,Victor Guryev,Bernard A. J. Roelen,Peter M. Lansdorp,Edwin Cuppen,Ewart Kuijk	2020	54
15	5-Fluorouracil treatment induces characteristic T>G mutations in human cancer Nature Communications ·Ruth Eaves,Bastiaan van der Roest,Nicolle Besselink,Roel Janssen,Sander Boymans,John W.M. Martens,Marie‐Laure Yaspo,Peter Priestley,Ewart Kuijk,Edwin Cuppen,Arne van Hoeck	2019	138
16	Mapping and phasing of structural variation in patient genomes using nanopore sequencing Nature Communications ·R.H. Maatman,Markus J. van Roosmalen,Ivo Renkens,Marleen M. Nieboer,Sjors Middelkamp,Joep de Ligt,Giulia Pregno,Daniela Giachino,Giorgia Mandrile,Jose Espejo Valle-Inclán,Jerome Korzelius,Ewart de Bruijn,Edwin Cuppen,Michael E. Talkowski,Tobias Marschall,Jeroen de Ridder,Wigard P. Kloosterman	2017	249
17	Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer Science ·Jarno Drost,Ruben van Boxtel,Francis Blokzijl,Tomohiro Mizutani,Nobuo Sasaki,Valentina Sasselli,Joep de Ligt,Sam Behjati,Judith E. Grolleman,Tom van Wezel,Serena Nik‐Zainal,Roland P. Kuiper,Edwin Cuppen,Hans Clevers	2017	312
18	Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure Scientific Reports ·Ewart Kuijk,Nanako Miura,Francis Blokzijl,Meritxell Huch,Helmuth Gehart,Pim W. Toonen,Harry Begthel,Hans Clevers,Aron M. Geurts,Edwin Cuppen	2016	47
19	Primary Colorectal Cancers and Their Subsequent Hepatic Metastases Are Genetically Different: Implications for Selection of Patients for Targeted Treatment Clinical Cancer Research ·Joost S.P. Vermaat,Isaäc J. Nijman,Marco J. Koudijs,Lauren F Bowen,Stefan Scherer,Michal Mokrý,Wijnand Roessingh,Nico Lansu,Ewart de Bruijn,Richard van Hillegersberg,P. J. van Diest,Edwin Cuppen,Emile E. Voest	2011	119
20	Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b Development ·Carolien Wansleeben,Harma Feitsma,Mireille Montcouquiol,C.C.M. Kroon,Edwin Cuppen,Frits Meijlink	2010	78

About Edwin Cuppen

Edwin Cuppen is a scholar working on Cancer Research, Aging, Genetics, Molecular Biology and Pathology and Forensic Medicine, having authored 278 papers that have together received 19.9k indexed citations. Recurring topics across this work include Cancer Genomics and Diagnostics (78 papers), Genetic factors in colorectal cancer (30 papers), CRISPR and Genetic Engineering (29 papers), Genomics and Rare Diseases (24 papers), Genomics and Chromatin Dynamics (20 papers), Genomics and Phylogenetic Studies (19 papers), Genomic variations and chromosomal abnormalities (18 papers) and MicroRNA in disease regulation (18 papers). The work is most often cited by research in Cancer Research (5.6k citations), Aging (386 citations), Molecular Biology (11.8k citations), Oncology (3.9k citations) and Genetics (3.7k citations). Edwin Cuppen has collaborated with scholars based in Netherlands, United States and Germany. Frequent co-authors include Eugène Berezikov, Ronald H.A. Plasterk, Isaäc J. Nijman, Hans Clevers, Ruben van Boxtel, Victor Guryev, Artem Tarasov, Albert J. Vilella, Pjotr Prins and Ewart de Bruijn. Their work appears in journals such as PLoS ONE, Nature Communications, Annals of Oncology, Genome Research and BMC Genomics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact