Chaitan Khosla

33.4k total citations · 3 hit papers
387 papers, 24.7k citations indexed

About

Chaitan Khosla is a scholar working on Pharmacology, Molecular Biology and Organic Chemistry. According to data from OpenAlex, Chaitan Khosla has authored 387 papers receiving a total of 24.7k indexed citations (citations by other indexed papers that have themselves been cited), including 214 papers in Pharmacology, 212 papers in Molecular Biology and 73 papers in Organic Chemistry. Recurrent topics in Chaitan Khosla's work include Microbial Natural Products and Biosynthesis (213 papers), Celiac Disease Research and Management (69 papers) and Genomics and Phylogenetic Studies (59 papers). Chaitan Khosla is often cited by papers focused on Microbial Natural Products and Biosynthesis (213 papers), Celiac Disease Research and Management (69 papers) and Genomics and Phylogenetic Studies (59 papers). Chaitan Khosla collaborates with scholars based in United States, Norway and United Kingdom. Chaitan Khosla's co-authors include David E. Cane, Ludvig M. Sollid, Gary M. Gray, Christopher T. Walsh, David A. Hopwood, Robert McDaniel, Lu Shan, Blaine A. Pfeifer, Susanne Ebert‐Khosla and Felix Hausch and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Chaitan Khosla

384 papers receiving 24.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structural Basis for Gluten Intolerance in Celiac Sprue

2002 1.2k citations Chaitan Khosla et al. Science profile →
A new enzyme superfamily — the phosphopantetheinyl transferases

1996 677 citations Chaitan Khosla et al. profile →
Biosynthesis of Complex Polyketides in a Metabolically Engineered Strain of E. coli

2001 598 citations David E. Cane, Chaitan Khosla et al. Science profile →

Peers

Countries citing papers authored by Chaitan Khosla

Since Specialization

Citations

This map shows the geographic impact of Chaitan Khosla's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Chaitan Khosla with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Chaitan Khosla more than expected).

Fields of papers citing papers by Chaitan Khosla

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Chaitan Khosla. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Chaitan Khosla. The network helps show where Chaitan Khosla may publish in the future.

Co-authorship network of co-authors of Chaitan Khosla

This figure shows the co-authorship network connecting the top 25 collaborators of Chaitan Khosla. A scholar is included among the top collaborators of Chaitan Khosla based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Chaitan Khosla. Chaitan Khosla is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A dendritic cell population responsible for transglutaminase 2–mediated gluten antigen presentation in celiac disease 2025 ·JCI Insight ·(unknown), Harrison A. Besser, (unknown), Megan A. Albertelli, Nielsen Fernandez‐Becker, Bana Jabrì, Chaitan Khosla	0
2	Past, Present, and Future of Noninvasive Tests to Assess Gluten Exposure, Celiac Disease Activity, and End-Organ Damage 2024 ·Gastroenterology ·Jocelyn A. Silvester, Luca Elli, Chaitan Khosla, (unknown)	5
3	Discovery and Characterization of the Fully Decorated Nocardiosis-Associated Polyketide Natural Product 2024 ·Journal of the American Chemical Society ·(unknown), Antonio Del Rio Flores, Stephen R. Lynch, Kai P. Yuet, Chaitan Khosla	3
4	Structural basis for intermodular communication in assembly-line polyketide biosynthesis 2024 ·Nature Chemical Biology ·D.P. Cogan, (unknown), Muyuan Chen, Yan Liu, (unknown), Chaitan Khosla	6
5	Characterization of the Flavin-Dependent Monooxygenase Involved in the Biosynthesis of the Nocardiosis-Associated Polyketide 2024 ·Biochemistry ·Antonio Del Rio Flores, Chaitan Khosla	1
6	Targeted Lysosomal Degradation of Secreted and Cell Surface Proteins through the LRP-1 Pathway 2023 ·Journal of the American Chemical Society ·(unknown), Harrison A. Besser, (unknown), Wei Zhang, Bianxiao Cui, Chaitan Khosla	29
7	Challenges in Harnessing Shared Within-Host Severe Acute Respiratory Syndrome Coronavirus 2 Variation for Transmission Inference 2023 ·Open Forum Infectious Diseases ·Katharine S. Walter, (unknown), Renu Verma, Jonathan Altamirano, (unknown), (unknown), Prasanna Jagannathan, Upinder Singh, Marisa Holubar, Aruna Subramanian, Chaitan Khosla, Yvonne Maldonado, Jason R. Andrews	2
8	LRP-1 links post-translational modifications to efficient presentation of celiac disease-specific T cell antigens 2023 ·Cell chemical biology ·(unknown), Harrison A. Besser, (unknown), (unknown), Bana Jabrì, Chaitan Khosla	13
9	Structure-Based Prototyping of Allosteric Inhibitors of Human Uridine/Cytidine Kinase 2 (UCK2) 2022 ·Biochemistry ·(unknown), (unknown), (unknown), Irimpan I. Mathews, Chaitan Khosla	1
10	In vivo visualization and molecular targeting of the cardiac conduction system 2022 ·Journal of Clinical Investigation ·William R. Goodyer, Benjamin Beyersdorf, Lauren Duan, Nynke S. van den Berg, Sruthi Mantri, Francisco X. Galdos, Nazan Puluca, Jan W. Buikema, Soah Lee, (unknown), Elise Robinson, Stephan Rogalla, D.P. Cogan, Chaitan Khosla, Eben L. Rosenthal, Sean M. Wu	8
11	Mapping the catalytic conformations of an assembly-line polyketide synthase module 2021 ·Science ·D.P. Cogan, Kaiming Zhang, Xiuyuan Li, Shanshan Li, Grigore Pintilie, Soung‐Hun Roh, Charles S. Craik, Wah Chiu, Chaitan Khosla	51
12	Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction 2020 ·Journal of the American Chemical Society ·D.P. Cogan, Xiuyuan Li, Natalia Sevillano, Irimpan I. Mathews, Tsutomu Matsui, Charles S. Craik, Chaitan Khosla	10
13	Cystamine and Disulfiram Inhibit Human Transglutaminase 2 via an Oxidative Mechanism 2018 ·Biochemistry ·Brad A. Palanski, Chaitan Khosla	28
14	Celiac Disease: Lessons for and from Chemical Biology 2017 ·ACS Chemical Biology ·Chaitan Khosla	9
15	Elucidation of the Cryptic Methyl Group Epimerase Activity of Dehydratase Domains from Modular Polyketide Synthases Using a Tandem Modules Epimerase Assay 2017 ·Journal of the American Chemical Society ·Xinqiang Xie, (unknown), Chaitan Khosla, David E. Cane	17
16	Mechanism and Stereochemistry of Polyketide Chain Elongation and Methyl Group Epimerization in Polyether Biosynthesis 2017 ·Journal of the American Chemical Society ·Xinqiang Xie, (unknown), Chaitan Khosla, David E. Cane	20
17	Expanding the Fluorine Chemistry of Living Systems Using Engineered Polyketide Synthase Pathways 2013 ·Science ·Mark C. Walker, B W. Thuronyi, Louise K. Charkoudian, Brian Lowry, Chaitan Khosla, Michelle C. Y. Chang	149
18	The 2.7-Å crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase 2006 ·Proceedings of the National Academy of Sciences ·Yinyan Tang, Chu‐Young Kim, Irimpan I. Mathews, David E. Cane, Chaitan Khosla	226
19	Engineered biosynthesis of an ansamycin polyketide precursor in Escherichia coli 2003 ·Proceedings of the National Academy of Sciences ·Kenji Watanabe, Mathew A. Rude, Christopher T. Walsh, Chaitan Khosla	70
20	Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel 2001 ·Proceedings of the National Academy of Sciences ·Shiou‐Chuan Tsai, Larry J. W. Miercke, J. Krucinski, Rajesh S. Gokhale, Julian C.‐H. Chen, Paul Foster, David E. Cane, Chaitan Khosla, Robert M. Stroud	179

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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