Philippa Marrack

61.7k total citations · 21 hit papers
425 papers, 51.7k citations indexed

About

Philippa Marrack is a scholar working on Immunology, Radiology, Nuclear Medicine and Imaging and Oncology. According to data from OpenAlex, Philippa Marrack has authored 425 papers receiving a total of 51.7k indexed citations (citations by other indexed papers that have themselves been cited), including 354 papers in Immunology, 93 papers in Radiology, Nuclear Medicine and Imaging and 58 papers in Oncology. Recurrent topics in Philippa Marrack's work include T-cell and B-cell Immunology (284 papers), Immune Cell Function and Interaction (259 papers) and Immunotherapy and Immune Responses (140 papers). Philippa Marrack is often cited by papers focused on T-cell and B-cell Immunology (284 papers), Immune Cell Function and Interaction (259 papers) and Immunotherapy and Immune Responses (140 papers). Philippa Marrack collaborates with scholars based in United States, China and France. Philippa Marrack's co-authors include John W. Kappler, J W Kappler, Neal W. Roehm, Janice White, Brian L. Kotzin, Ann M. Pullen, David A. Hildeman, Ralph T. Kubo, Andrew Herman and Frances Crawford and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Philippa Marrack

422 papers receiving 49.9k citations

Hit Papers

T cell tolerance by clonal elimination in the thymus 1981 2026 1996 2011 1987 1990 1983 1989 1981 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. T cell tolerance by clonal elimination in the thymus
    1987 1.8k citations John W. Kappler, Philippa Marrack et al. profile →
  2. The Staphylococcal Enterotoxins and Their Relatives
    1990 1.6k citations Philippa Marrack et al. Science profile →
  3. Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity
    1983 962 citations Philippa Marrack, John W. Kappler et al. profile →
  4. The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice
    1989 936 citations John W. Kappler, Philippa Marrack et al. profile →
  5. Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition
    1981 910 citations Philippa Marrack et al. The Journal of Experimental Medicine profile →
  6. Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex
    1988 901 citations John W. Kappler, Janice White et al. profile →
  7. Interaction of Staphylococcus aureus toxin "superantigens" with human T cells.
    1989 873 citations Brian L. Kotzin, Philippa Marrack et al. Proceedings of the National Academy of Sciences profile →
  8. Normal Development of Mice Deficient in β 2 M, MCClass I Proteins, and CD8 + T Cells
    1990 781 citations Philippa Marrack, John W. Kappler et al. Science profile →
  9. The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody.
    1983 751 citations John W. Kappler, Philippa Marrack et al. The Journal of Experimental Medicine profile →
  10. Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors.
    1989 715 citations John W. Kappler, Philippa Marrack et al. profile →
  11. Control of Homeostasis of CD8 + Memory T Cells by Opposing Cytokines
    2000 702 citations Masaaki Murakami, Akemi Sakamoto et al. Science profile →
  12. Superantigens: Mechanism of T-Cell Stimulation and Role in Immune Responses
    1991 683 citations Philippa Marrack et al. profile →
  13. Towards an understanding of the adjuvant action of aluminium
    2009 652 citations Philippa Marrack, Amy S. McKee et al. profile →
  14. Type I Interferons Keep Activated T Cells Alive
    1999 631 citations Philippa Marrack, John W. Kappler et al. The Journal of Experimental Medicine profile →
  15. Vβ-Specific Stimulation of Human T Cells by Staphylococcal Toxins
    1989 611 citations Brian L. Kotzin, Philippa Marrack et al. Science profile →
  16. Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing.
    1983 593 citations John W. Kappler, Philippa Marrack et al. The Journal of Experimental Medicine profile →
  17. Toll-like receptor 7 (TLR7)–driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity
    2011 559 citations Anatoly V. Rubtsov, Kira Rubtsova et al. Blood profile →
  18. Evidence for the Effects of a Superantigen in Rheumatoid Arthritis
    1991 548 citations John W. Kappler, Philippa Marrack et al. Science profile →
  19. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder
    2004 534 citations Michael B. Jordan, David A. Hildeman et al. Blood profile →
  20. Superantigens and Their Potential Role in Human Disease
    1993 509 citations Brian L. Kotzin, John W. Kappler et al. profile →
  21. Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen
    1987 306 citations John W. Kappler, Philippa Marrack et al. profile →

Peers

Philippa Marrack
John W. Kappler United States
Charles A. Janeway United States
Thomas A. Waldmann United States
William E. Paul United States
Emil R. Unanue United States
Ronald N. Germain United States
Rolf M. Zinkernagel Switzerland
Ethan M. Shevach United States
Michel C. Nussenzweig United States
Jeffrey V. Ravetch United States
John W. Kappler United States
Philippa Marrack
Citations per year, relative to Philippa Marrack Philippa Marrack (= 1×) peers John W. Kappler

Countries citing papers authored by Philippa Marrack

Since Specialization
Citations

This map shows the geographic impact of Philippa Marrack's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Philippa Marrack with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Philippa Marrack more than expected).

Fields of papers citing papers by Philippa Marrack

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philippa Marrack. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philippa Marrack. The network helps show where Philippa Marrack may publish in the future.

Co-authorship network of co-authors of Philippa Marrack

This figure shows the co-authorship network connecting the top 25 collaborators of Philippa Marrack. A scholar is included among the top collaborators of Philippa Marrack based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Philippa Marrack. Philippa Marrack is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Liu, Haolin, Pengcheng Wei, Qianqian Zhang, et al.. (2021). 501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to bamlanivimab in vitro. mAbs. 13(1). 1919285–1919285. 56 indexed citations
2.
Gray, Joshua I., Fraser Morton, Eric T. Clambey, et al.. (2020). Tolerance induction in memory CD4 T cells is partial and reversible. Immunology. 162(1). 68–83. 4 indexed citations
3.
Crawford, Frances, Ryan C. Hill, Niyun Jin, et al.. (2020). Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation. The Journal of Experimental Medicine. 218(2). 46 indexed citations
4.
Wang, Yang, Tomasz Sosinowski, Frances Crawford, et al.. (2019). How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Science Immunology. 4(34). 40 indexed citations
5.
Jin, Niyun, Yang Wang, Frances Crawford, et al.. (2015). N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes. Proceedings of the National Academy of Sciences. 112(43). 13318–13323. 42 indexed citations
6.
David, Alexandria, Frances Crawford, Paul Garside, et al.. (2014). Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation. Proceedings of the National Academy of Sciences. 111(21). 7735–7740. 15 indexed citations
7.
Falta, Michael T., Clemencia Pinilla, Douglas G. Mack, et al.. (2013). Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease. The Journal of Experimental Medicine. 210(7). 1403–1418. 49 indexed citations
8.
McKee, Amy S., Matthew A. Burchill, Michael W. Munks, et al.. (2013). Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells. Proceedings of the National Academy of Sciences. 110(12). E1122–31. 112 indexed citations
9.
Rubtsova, Kira, Anatoly V. Rubtsov, Linda F. van Dyk, John W. Kappler, & Philippa Marrack. (2013). T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance. Proceedings of the National Academy of Sciences. 110(34). E3216–24. 210 indexed citations
10.
Thurman, Joshua M., Anatoly V. Rubtsov, Philippa Marrack, et al.. (2012). Murine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity. Proceedings of the National Academy of Sciences. 109(18). E1092–100. 28 indexed citations
11.
Yin, Lei, Frances Crawford, Philippa Marrack, John W. Kappler, & Shaodong Dai. (2012). T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proceedings of the National Academy of Sciences. 109(45). 18517–18522. 39 indexed citations
12.
Rubtsov, Anatoly V., Kira Rubtsova, Aryeh Fischer, et al.. (2011). Toll-like receptor 7 (TLR7)–driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity. Blood. 118(5). 1305–1315. 559 indexed citations breakdown →
13.
Stadinski, Brian D., Li Zhang, Frances Crawford, et al.. (2010). Diabetogenic T cells recognize insulin bound to IA g7 in an unexpected, weakly binding register. Proceedings of the National Academy of Sciences. 107(24). 10978–10983. 164 indexed citations
14.
Murakami, Masaaki, Chika Kitabayashi, Naoko Ueda, et al.. (2007). Homeostatically proliferating CD4+ T cells are involved in the pathogenesis of an Omenn syndrome murine model. Journal of Clinical Investigation. 117(5). 1270–1281. 58 indexed citations
15.
Willis, Richard A., John W. Kappler, & Philippa Marrack. (2006). CD8 T cell competition for dendritic cells in vivo is an early event in activation. Proceedings of the National Academy of Sciences. 103(32). 12063–12068. 74 indexed citations
16.
Peyerl, Fred W., Shaodong Dai, Guinevere A. Murphy, et al.. (2006). Elucidation of some Bax conformational changes through crystallization of an antibody–peptide complex. Cell Death and Differentiation. 14(3). 447–452. 43 indexed citations
17.
Zhu, Yanan, Bradley Jay Swanson, Michael Wang, et al.. (2004). Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells. Proceedings of the National Academy of Sciences. 101(20). 7681–7686. 104 indexed citations
18.
Jordan, Michael B., David M. Mills, John W. Kappler, Philippa Marrack, & John C. Cambier. (2004). Promotion of B Cell Immune Responses via an Alum-Induced Myeloid Cell Population. Science. 304(5678). 1808–1810. 188 indexed citations
19.
Hildeman, David A., Thomas C. Mitchell, John W. Kappler, & Philippa Marrack. (2003). T cell apoptosis and reactive oxygen species. Journal of Clinical Investigation. 111(5). 575–581. 127 indexed citations
20.
Liu, Xinqi, et al.. (2002). Alternate interactions define the binding of peptides to the MHC molecule IA b. Proceedings of the National Academy of Sciences. 99(13). 8820–8825. 62 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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