Jacques Neefjes

39.1k citations

339 papers · 29.6k indexed · 9 hit papers · h-index 91

Impact in

Immunology top 0.05%
- Immunotherapy and Immune Responses
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
Physiology top 0.1%

Papers in

Immunology 149
- Immunotherapy and Immune Responses 112
- Immune Cell Function and Interaction 77
- T-cell and B-cell Immunology 76
Physiology 18

Co-authors: Eric A. Reits Hidde L. Ploegh Lennert Janssen Frank Momburg Marlieke L.M. Jongsma Petra Paul Günter J. Hämmerling Hans Janssen
Journals: The Journal of Immunology (27 papers)European Journal of Immunology (22 papers)Journal of Cell Science (16 papers)The Journal of Experimental Medicine (12 papers)Immunity (9 papers)
Partner nations: Netherlands United States United Kingdom

In The Last Decade

Jacques Neefjes

334 papers receiving 29.1k citations

Hit Papers

9 papers align trajectories log scale

New insights into the activities and toxicities of the old anticancer drug doxorubicin 2020 · 266 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2020 FEBS Journal
2016 Trends in Immunology
2011 Nature reviews. Immunology
2009 The Journal of Cell Biology
2006 The Journal of Experimental Medicine
2001 Current Biology
1991 Nature
1990 Nature
1987 Nature

Peers

Countries citing papers authored by Jacques Neefjes

Since Specialization

Citations

This map shows the geographic impact of Jacques Neefjes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jacques Neefjes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jacques Neefjes more than expected).

Fields of papers citing papers by Jacques Neefjes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jacques Neefjes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jacques Neefjes. The network helps show where Jacques Neefjes may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jacques Neefjes, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jacques Neefjes Line = papers co-authored together Jacques Neefjes links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The trajectory of fatigue over time in breast cancer patients treated with chemotherapy: exploring the effect of anthracycline-based chemotherapy The Breast ·PATRICIA M. GOFF, Laura Kervezee, Claudia A. Bargon, Daniel J. Evers, А. Л. Бурдяло, V. S. Kadyrova, Ashima Singal, Hans Gelderblom, Jacques Neefjes, Dave Neilipovitz, Shavonne Coleman	2026	0
2	The Impact of Chemotherapy and Body Mass Index on Cancer‐Related Fatigue in Colon Cancer Patients: A PROFILES ‐Registry Study Cancer Medicine ·PATRICIA M. GOFF, Floortje Mols, Laura Kervezee, Niels H. Chavannes, Hans Gelderblom, Jacques Neefjes, Chris Hinnen	2025	2
3	The ORP9-ORP11 dimer promotes sphingomyelin synthesis eLife ·Birol Cabukusta, Daniel J. Siegwart, Jimmy J.L.L. Akkermans, Carol F. Nicholson, Aat A. Mulder, Roman I. Koning, Martin Giera, Jacques Neefjes	2024	5
4	The ORP9-ORP11 dimer promotes sphingomyelin synthesis eLife ·Birol Cabukusta, Daniel J. Siegwart, Jimmy J.L.L. Akkermans, Carol F. Nicholson, Aat A. Mulder, Roman I. Koning, Martin Giera, Jacques Neefjes	2023	1
5	SKIP ‐ HOPS recruits TBC 1D15 for a Rab7‐to‐Arl8b identity switch to control late endosome transport The EMBO Journal ·Marlieke L.M. Jongsma, Jeroen Bakker, Birol Cabukusta, Nalan Liv, Daphne M. van Elsland, Job Fermie, Y Raffray, Coenraad Kuijl, Sabina Y. van der Zanden, Lennert Janssen, 裕義内藤, Rik van der Kant, Ruud H. Wijdeven, Judith Klumperman, Ilana Berlin, Jacques Neefjes	2020	86
6	The journey of Ca2+ through the cell – pulsing through the network of ER membrane contact sites Journal of Cell Science ·Tom Cremer, Jacques Neefjes, Ilana Berlin	2020	23
7	Modulation of TAP-dependent antigen compartmentalization during human monocyte-to-DC differentiation Blood Advances ·Marius Döring, H. Blees, Nicole Koller, Hitosi SAGAWA, Mathias Müsken, Jozef Vakula, Stephan Becker, Elena Grabski, Junxi Wang, Hans Janssen, Werner Zuschratter, Jacques Neefjes, Frank Klawonn, Britta Eiz‐Vesper, Robert Tampé, Ulrich Kalinke	2019	16
8	Chemical and genetic control of IFN γ‐induced MHCII expression EMBO Reports ·Ruud H. Wijdeven, Marvin M. van Luijn, Annet F. Wierenga‐Wolf, Jimmy J.L.L. Akkermans, Peter J. van den Elsen, Rogier Q. Hintzen, Jacques Neefjes	2018	25
9	Drug Discovery Maps, a Machine Learning Model That Visualizes and Predicts Kinome–Inhibitor Interaction Landscapes Journal of Chemical Information and Modeling ·Antonius P. A. Janssen, Rita Ann Walker, Ruud H. Wijdeven, Eelke B. Lenselink, Jacques Neefjes, C. A. A. VAN BOECKEL, Gerard J. P. van Westen, Mario van der Stelt	2018	54
10	Creating molecules that modulate immune responses Nature Reviews Chemistry ·Sander I. van Kasteren, Jacques Neefjes, Huib Ovaa	2018	17
11	A flexible MHC class I multimer loading system for large-scale detection of antigen-specific T cells The Journal of Experimental Medicine ·Zamani Arman, Malgorzata Garstka, C M NAWALAGATTI, Anke Redeker, George M. C. Janssen, Peter A. van Veelen, Ramon Arens, J.H. Frederik Falkenburg, Jacques Neefjes, Huib Ovaa	2018	27
12	Chemical Profiling of Primary Mesothelioma Cultures Defines Subtypes with Different Expression Profiles and Clinical Responses Clinical Cancer Research ·Keita Hiidome, Josine M.M.F. Quispel-Janssen, Yongsoo Kim, Constantine Alifrangis, Wilbert Zwart, Paul Baas, Jacques Neefjes	2017	9
13	Comprehensive Pharmacogenomic Profiling of Malignant Pleural Mesothelioma Identifies a Subgroup Sensitive to FGFR Inhibition Clinical Cancer Research ·Josine M.M.F. Quispel-Janssen, Jitendra Badhai, Keita Hiidome, Stacey Price, Jonathan Brammeld, Francesco Iorio, Krishna K. Kolluri, Matthew Garnett, Anton Berns, Paul Baas, Ultan McDermott, Jacques Neefjes, Constantine Alifrangis	2017	32
14	Photo-crosslinking of clinically relevant kinases using H89-derived photo-affinity probes Molecular BioSystems ·Sara Christina Stolze, Guo Xuejiao, Ruud H. Wijdeven, Adriaan W. Tuin, Adrianus M. C. H. van den Nieuwendijk, Bogdan I. Florea, Mario van der Stelt, Gijsbert A. van der Marel, Jacques Neefjes, Herman S. Overkleeft	2016	1
15	The first step of peptide selection in antigen presentation by MHC class I molecules Proceedings of the National Academy of Sciences ·Malgorzata Garstka, Alexander Fish, Patrick H. N. Celie, Robbie P. Joosten, George M. C. Janssen, Ilana Berlin, Melanie Köhler, Quan Z. Sheng, Lennert Janssen, Huib Ovaa, Peter A. van Veelen, Anastassis Perrakis, Jacques Neefjes	2015	66
16	Genome-Wide Identification and Characterization of Novel Factors Conferring Resistance to Topoisomerase II Poisons in Cancer Cancer Research ·Ruud H. Wijdeven, Baoxu Pang, Sabina Y. van der Zanden, Xiaohang Qiao, Vincent A. Blomen, Marlous Hoogstraat, Esther H. Lips, Lennert Janssen, Lodewyk F.A. Wessels, Thijn R. Brummelkamp, Jacques Neefjes	2015	56
17	Reciprocal chemical genetics for swift lead and target identification Molecular BioSystems ·Coenraad Kuijl, Adriaan W. Tuin, Herman S. Overkleeft, Jacques Neefjes	2008	2
18	A CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates The Journal of Experimental Medicine ·Andrew D. Hislop, Maaike E. Ressing, Daphne van Leeuwen, Anning Wen, Daniëlle Horst, Danijela Koppers‐Lalic, Nathan P. Croft, Jacques Neefjes, Alan B. Rickinson, Emmanuel J. H. J. Wiertz	2007	145
19	Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy The Journal of Experimental Medicine ·Eric A. Reits, James W. Hodge, Carla Herberts, Tom A. Groothuis, Mala Chakraborty, Elizabeth K. Wansley, Kevin Camphausen, Rosalie M. Luiten, Reski Rumondang, Joost Neijssen, Alexander Griekspoor, Elly Mesman, Frank A. W. Verreck, Hergen Spits, Jeffrey Schlom, Peter A. van Veelen, Jacques Neefjes Hit paper breakdown →	2006	1346
20	HFE cross-talks with the MHC class I antigen presentation pathway Blood ·Sérgio F. de Almeida, Isabel Fidalgo-Carvalho, Carla Cardoso, João V. Cordeiro, Jorge E. Azevedo, Jacques Neefjes, Maria de Sousa	2005	49

About Jacques Neefjes

Jacques Neefjes is a scholar working on Immunology, Physiology, Cell Biology, Molecular Biology and Oncology, having authored 339 papers that have together received 29.6k indexed citations. Recurring topics across this work include Immunotherapy and Immune Responses (112 papers), Immune Cell Function and Interaction (77 papers), T-cell and B-cell Immunology (76 papers), Cellular transport and secretion (46 papers), Ubiquitin and proteasome pathways (40 papers), Glycosylation and Glycoproteins Research (24 papers), Monoclonal and Polyclonal Antibodies Research (22 papers) and RNA Interference and Gene Delivery (21 papers). The work is most often cited by research in Immunology (13.9k citations), Physiology (1.2k citations), Cell Biology (4.2k citations), Virology (1.1k citations) and Oncology (5.5k citations). Jacques Neefjes has collaborated with scholars based in Netherlands, United States and United Kingdom. Frequent co-authors include Eric A. Reits, Hidde L. Ploegh, Lennert Janssen, Frank Momburg, Marlieke L.M. Jongsma, Petra Paul, Günter J. Hämmerling, Hans Janssen, Oddmund Bakke and Tom A. Groothuis. Their work appears in journals such as The Journal of Immunology, European Journal of Immunology, Journal of Cell Science, The Journal of Experimental Medicine and Immunity.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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