Wibke E. Diederich

2.0k citations

55 papers · 1.6k indexed · h-index 22

Cancer Research top 10%
Molecular Biology top 10%
- Chemical Synthesis and Analysis 10
- Peroxisome Proliferator-Activated Receptors 9
Computational Theory and Mathematics top 5%
- Computational Drug Discovery Methods 11
Virology top 10%
- HIV Research and Treatment 6
Organic Chemistry top 10%
- Click Chemistry and Applications 4
- Synthetic Organic Chemistry Methods 4
Infectious Diseases
- HIV/AIDS drug development and treatment 10
Public Health, Environmental and Occupational Health
- Malaria Research and Control 4

Co-authors: G. Klebe Michael Daude Robert Grosse Carsten Culmsee Andreas Blum Anja Jelinek Matthias Plessner H. Steuber
Cited by: Cancer Research Molecular Biology Computational Theory and Mathematics
Journals: Nucleic Acids Research (2 papers)Angewandte Chemie International Edition (2 papers)Journal of Molecular Biology (2 papers)
Partner nations: Germany United States India

In The Last Decade

Wibke E. Diederich

53 papers receiving 1.5k citations

Peers

Countries citing papers authored by Wibke E. Diederich

Since Specialization

Citations

This map shows the geographic impact of Wibke E. Diederich's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Wibke E. Diederich with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Wibke E. Diederich more than expected).

Fields of papers citing papers by Wibke E. Diederich

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wibke E. Diederich. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wibke E. Diederich. The network helps show where Wibke E. Diederich may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Wibke E. Diederich, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Wibke E. Diederich Line = papers co-authored together Wibke E. Diederich links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer Gut ·Anna Brichkina,Miriam Ems,Роман В. Суезов,Rajeev Singh,Veronika Lutz,Felix S.R. Picard,Andrea Nist,Thorsten Stiewe,Johannes Graumann,Michael Daude,Wibke E. Diederich,Florian Finkernagel,Ho‐Ryun Chung,Detlef K. Bartsch,Katrin Roth,Corinna U. Keber,Carsten Denkert,Magdalena Huber,Thomas M. Gress,Matthias Lauth	2024	8
2	Tumor-suppressive disruption of cancer subtype-associated super enhancer circuits by small molecule treatment NAR Cancer ·Anke Koeniger,Pierfrancesco Polo,Anna Brichkina,Florian Finkernagel,Alexander Visekruna,Andrea Nist,Thorsten Stiewe,Michael Daude,Wibke E. Diederich,Thomas M. Gress,Till Adhikary,Matthias Lauth	2023	2
3	Inhibiting Hedgehog: An Update on Pharmacological Compounds and Targeting Strategies Journal of Medicinal Chemistry ·Ilya Galperin,Lukas Dempwolff,Wibke E. Diederich,Matthias Lauth	2019	26
4	The Bacterial Product Violacein Exerts an Immunostimulatory Effect Via TLR8 Scientific Reports ·Francisco A. Venegas,Gabriele Köllisch,Kerstin Mark,Wibke E. Diederich,Andreas M. Kaufmann,Stefan Bauer,Max Chavarría,Juan J. Araya,Alfonso Garcı́a-Piñeres	2019	31
5	Structural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus Virology ·Manuel Kanitz,Sandra Blanck,A. Heine,Anastasia Gulyaeva,Alexander E. Gorbalenya,John Ziebuhr,Wibke E. Diederich	2019	11
6	Binding-Site Compatible Fragment Growing Applied to the Design of β₂-Adrenergic Receptor Ligands Journal of Medicinal Chemistry ·Florent Chevillard,Helena Rimmer,Cecilia Betti,Els Pardon,Steven Ballet,Niek van Hilten,Jan Steyaert,Wibke E. Diederich,Peter Kolb	2018	37
7	Price for Opening the Transient Specificity Pocket in Human Aldose Reductase upon Ligand Binding: Structural, Thermodynamic, Kinetic, and Computational Analysis ACS Chemical Biology ·C. Rechlin,Frithjof Scheer,Felix Terwesten,Tobias Wulsdorf,Ewa Pol,Veronica Fridh,Philipp M. Toth,Wibke E. Diederich,A. Heine,G. Klebe	2017	22
8	One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit Lists ChemMedChem ·J. Schiebel,Nedyalka Radeva,Helene Köster,A. Metz,Timo Krotzky,Maren Kuhnert,Wibke E. Diederich,A. Heine,Lars Neumann,Cédric Atmanène,Dominique Roecklin,Valérie Vivat‐Hannah,Jean‐Paul Renaud,Robert Meinecke,Nina Schlinck,Astrid Sitte,Franziska Popp,Markus Zeeb,G. Klebe	2015	52
9	The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state Nucleic Acids Research ·Till Adhikary,Annika Wortmann,Tim Schumann,Florian Finkernagel,Sonja Lieber,Katrin Roth,Philipp M. Toth,Wibke E. Diederich,Andrea Nist,Thorsten Stiewe,Lara Kleinesudeik,Silke Reinartz,Sabine Müller‐Brüsselbach,Rolf Müller	2015	66
10	Tracing Binding Modes in Hit‐to‐Lead Optimization: Chameleon‐Like Poses of Aspartic Protease Inhibitors Angewandte Chemie International Edition ·Maren Kuhnert,Helene Köster,Ruben Bartholomäus,Ah Young Park,Amir Shahim,A. Heine,H. Steuber,G. Klebe,Wibke E. Diederich	2015	25
11	Flavonoids as noncompetitive inhibitors of Dengue virus NS2B-NS3 protease: Inhibition kinetics and docking studies Bioorganic & Medicinal Chemistry ·Lorena Ramos Freitas de Sousa,Hongmei Wu,Liliane Nebo,João Batista Fernandes,Maria Fátima das Graças Fernandes da Silva,Werner Kiefer,Manuel Kanitz,Jochen Bodem,Wibke E. Diederich,Tanja Schirmeister,Paulo C. Vieira	2014	123
12	Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion Oncogene ·Till Adhikary,Dominique T. Brandt,Kerstin Kaddatz,Josefine Stockert,Simone Naruhn,Wolfgang Meißner,Florian Finkernagel,Julia Obert,Sonja Lieber,Maren Scharfe,Michael Jarek,Philipp M. Toth,Frithjof Scheer,Wibke E. Diederich,Silke Reinartz,Robert Grosse,Sabine Müller‐Brüsselbach,Rolf Müller	2012	75
13	Development of Improved PPARβ/δ Inhibitors ChemMedChem ·Philipp M. Toth,Simone Naruhn,Veronika F.S. Pape,Stefanie Dörr,G. Klebe,Rolf Müller,Wibke E. Diederich	2011	26
14	High-Affinity Peroxisome Proliferator-Activated Receptor β/δ-Specific Ligands with Pure Antagonistic or Inverse Agonistic Properties Molecular Pharmacology ·Simone Naruhn,Philipp M. Toth,Till Adhikary,Kerstin Kaddatz,Veronika F.S. Pape,Stefanie Dörr,G. Klebe,Sabine Müller‐Brüsselbach,Wibke E. Diederich,Rolf Müller	2011	35
15	Two Solutions for the Same Problem: Multiple Binding Modes of Pyrrolidine-Based HIV-1 Protease Inhibitors Journal of Molecular Biology ·Andreas Blum,Jark Böttcher,Stefanie Dörr,A. Heine,G. Klebe,Wibke E. Diederich	2011	8
16	Fragment‐Based Lead Discovery: Screening and Optimizing Fragments for Thermolysin Inhibition ChemMedChem ·Lisa Englert,Katrin Silber,H. Steuber,Sascha Brass,Björn Over,Hans‐Dieter Gerber,A. Heine,Wibke E. Diederich,G. Klebe	2010	24
17	Stability-indicating HPLC assays for the determination of piritramide and droperidol in PCA solution Journal of Clinical Pharmacy and Therapeutics ·S. Selbach,Wibke E. Diederich,S. Fett,Detlef Fründ,T. Koch,Leopold Eberhart	2010	7
18	Pyrrolidine Derivatives as Plasmepsin Inhibitors: Binding Mode Analysis Assisted by Molecular Dynamics Simulations of a Highly Flexible Protein ChemMedChem ·Torsten Luksch,Andreas Blum,Nina Klee,Wibke E. Diederich,Christoph Sotriffer,G. Klebe	2010	12
19	Targeting the Open‐Flap Conformation of HIV‐1 Protease with Pyrrolidine‐Based Inhibitors ChemMedChem ·Jark Böttcher,Andreas Blum,Stefanie Dörr,A. Heine,Wibke E. Diederich,G. Klebe	2008	27
20	KNOBLE: A Knowledge‐Based Approach for the Design and Synthesis of Readily Accessible Small‐Molecule Chemical Probes To Test Protein Binding Angewandte Chemie International Edition ·Christof Gerlach,Martin Münzel,Bernhard Baum,Hans‐Dieter Gerber,Tobias Craan,Wibke E. Diederich,G. Klebe	2007	10

About Wibke E. Diederich

Wibke E. Diederich is a scholar working on Virology, Computational Theory and Mathematics and Infectious Diseases, having authored 55 papers that have together received 1.6k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (11 papers), HIV/AIDS drug development and treatment (10 papers), Chemical Synthesis and Analysis (10 papers), Peroxisome Proliferator-Activated Receptors (9 papers), HIV Research and Treatment (6 papers), Click Chemistry and Applications (4 papers), Synthetic Organic Chemistry Methods (4 papers) and Malaria Research and Control (4 papers). The work is most often cited by research in Cancer Research (277 citations), Molecular Biology (842 citations) and Computational Theory and Mathematics (184 citations). Wibke E. Diederich has collaborated with scholars based in Germany, United States and India. Frequent co-authors include G. Klebe, Michael Daude, Robert Grosse, Carsten Culmsee, Andreas Blum, Anja Jelinek, Matthias Plessner, H. Steuber, A. Heine and Rolf Müller. Their work appears in journals such as Nucleic Acids Research, Angewandte Chemie International Edition and Journal of Molecular Biology.

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