Yadong Huang

20.0k total citations · 7 hit papers
143 papers, 13.9k citations indexed

About

Yadong Huang is a scholar working on Physiology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Yadong Huang has authored 143 papers receiving a total of 13.9k indexed citations (citations by other indexed papers that have themselves been cited), including 75 papers in Physiology, 58 papers in Molecular Biology and 37 papers in Cellular and Molecular Neuroscience. Recurrent topics in Yadong Huang's work include Alzheimer's disease research and treatments (72 papers), Neuroinflammation and Neurodegeneration Mechanisms (20 papers) and Neuroscience and Neuropharmacology Research (19 papers). Yadong Huang is often cited by papers focused on Alzheimer's disease research and treatments (72 papers), Neuroinflammation and Neurodegeneration Mechanisms (20 papers) and Neuroscience and Neuropharmacology Research (19 papers). Yadong Huang collaborates with scholars based in United States, China and Germany. Yadong Huang's co-authors include Robert W. Mahley, Lennart Mucke, Karl H. Weisgraber, Gerd Assmann, Qin Xu, David Walker, Stanley C. Rall, Walter J. Brecht, Seo Yeon Yoon and Maureen E. Balestra and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Yadong Huang

140 papers receiving 13.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Alzheimer Mechanisms and Therapeutic Strategies

2012 1.4k citations Yadong Huang, Lennart Mucke profile →
Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer’s disease

2006 726 citations Robert W. Mahley, Karl H. Weisgraber et al. profile →
High-density lipoprotein cholesterol as a predictor of coronary heart disease risk. The PROCAM experience and pathophysiological implications for reverse cholesterol transport

1996 571 citations Yadong Huang et al. profile →
Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases

2014 533 citations Yadong Huang, Robert W. Mahley profile →
Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor

2012 411 citations Maureen E. Balestra, Yaisa Andrews‐Zwilling et al. Cell stem cell profile →
Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector

2018 284 citations Ramsey Najm, Qin Xu et al. profile →
Cell type-specific roles of APOE4 in Alzheimer disease

2024 69 citations Jessica Blumenfeld, Oscar Yip et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Yadong Huang United States	63	6.9k	5.3k	2.7k	2.4k	1.9k	143	13.9k
Huaxi Xu United States	75	11.9k 1.7×	8.3k 1.6×	3.5k 1.3×	937 0.4×	4.7k 2.5×	195	21.4k
G. William Rebeck United States	62	6.8k 1.0×	4.4k 0.8×	2.1k 0.8×	1.0k 0.4×	1.8k 0.9×	138	11.2k
Mary Jo LaDu United States	51	7.1k 1.0×	3.8k 0.7×	2.0k 0.7×	1.1k 0.4×	1.9k 1.0×	105	9.6k
Sam Gandy United States	74	13.2k 1.9×	8.1k 1.5×	3.7k 1.3×	875 0.4×	2.8k 1.5×	292	21.5k
Michael P. Vitek United States	64	7.0k 1.0×	6.1k 1.2×	2.7k 1.0×	633 0.3×	2.7k 1.4×	181	14.5k
Kelly R. Bales United States	66	12.1k 1.8×	6.1k 1.2×	3.9k 1.4×	1.4k 0.6×	3.8k 2.0×	126	17.1k
Steven M. Paul United States	66	11.6k 1.7×	5.6k 1.1×	3.7k 1.4×	1.4k 0.6×	3.8k 2.0×	117	16.4k
Fernanda G. De Felice Brazil	55	6.5k 1.0×	3.5k 0.7×	2.2k 0.8×	500 0.2×	2.2k 1.2×	114	10.9k
Robert E. Pitas United States	51	4.2k 0.6×	4.7k 0.9×	1.5k 0.6×	3.2k 1.3×	836 0.4×	88	11.0k
Seth Love United Kingdom	67	6.9k 1.0×	4.7k 0.9×	2.7k 1.0×	735 0.3×	4.0k 2.1×	319	16.8k

Countries citing papers authored by Yadong Huang

Since Specialization

Citations

This map shows the geographic impact of Yadong Huang's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yadong Huang with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yadong Huang more than expected).

Fields of papers citing papers by Yadong Huang

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yadong Huang. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yadong Huang. The network helps show where Yadong Huang may publish in the future.

Co-authorship network of co-authors of Yadong Huang

This figure shows the co-authorship network connecting the top 25 collaborators of Yadong Huang. A scholar is included among the top collaborators of Yadong Huang based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yadong Huang. Yadong Huang is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Huang, Yadong, et al.. (2025). Clonidine Ameliorates Neuroinflammation in the Rat Model of Tourette Syndrome. Journal of Neuroimmune Pharmacology. 20(1). 56–56.

Chen, Nuo, Min Joo Kim, Jessica Blumenfeld, et al.. (2024). Microglia depletion reduces human neuronal APOE4-related pathologies in a chimeric Alzheimer’s disease model. Cell stem cell. 32(1). 86–104.e7. 20 indexed citations

Vance, Jeffery M., Lindsay A. Farrer, Yadong Huang, et al.. (2024). Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer's Disease. Annals of Neurology. 95(4). 625–634. 21 indexed citations

Li, Yuxiao, Xin Luo, Zhao Yue-ping, et al.. (2023). Research Advances on Stem Cell-Derived Extracellular Vesicles Promoting the Reconstruction of Alveolar Bone through RANKL/RANK/OPG Pathway. Journal of Functional Biomaterials. 14(4). 193–193. 6 indexed citations

Sallam, Ahmad H., et al.. (2023). Meta‐analysis of the genetics of resistance to Fusarium head blight and deoxynivalenol accumulation in barley and considerations for breeding. Plant Breeding. 143(1). 2–25. 5 indexed citations

Li, Huihui, Caroline Guglielmetti, Yoshitaka Sei, et al.. (2023). Neurons require glucose uptake and glycolysis in vivo. Cell Reports. 42(4). 112335–112335. 71 indexed citations

Koutsodendris, Nicole, Jessica Blumenfeld, Ayushi Agrawal, et al.. (2023). Neuronal APOE4 removal protects against tau-mediated gliosis, neurodegeneration and myelin deficits. Nature Aging. 3(3). 275–296. 64 indexed citations

Jones, Emily A Aery, Misha Zilberter, Biljana Djukic, et al.. (2021). Dentate gyrus and CA3 GABAergic interneurons bidirectionally modulate signatures of internal and external drive to CA1. Cell Reports. 37(13). 110159–110159. 17 indexed citations

Xu, Lin, Yadong Huang, Jun Ouyang, et al.. (2020). 4E-BP1Thr46 Phosphorylation Association with Poor Prognosis in Quantitative Phosphoproteomics of Portal Vein Tumor Thrombus Revealed that 4E-BP1Thr46 Phosphorylation is Associated with Poor Prognosis in HCC. SHILAP Revista de lepidopterología. 1 indexed citations

10.

Najm, Ramsey, Kelly A. Zalocusky, Misha Zilberter, et al.. (2020). In Vivo Chimeric Alzheimer’s Disease Modeling of Apolipoprotein E4 Toxicity in Human Neurons. Cell Reports. 32(4). 107962–107962. 32 indexed citations

11.

Yang, Yan, Zhijian Su, Jiao Luo, et al.. (2014). Directed Mouse Embryonic Stem Cells into Leydig-Like Cells Rescue Testosterone-Deficient Male Rats In Vivo. Stem Cells and Development. 24(4). 459–470. 36 indexed citations

12.

Bien‐Ly, Nga, Anna K. Gillespie, David Walker, Seo Yeon Yoon, & Yadong Huang. (2012). Reducing Human Apolipoprotein E Levels Attenuates Age-Dependent Aβ Accumulation in Mutant Human Amyloid Precursor Protein Transgenic Mice. Journal of Neuroscience. 32(14). 4803–4811. 124 indexed citations

13.

Brodbeck, Jens, Zhaoping Liu, Anke Meyer‐Franke, et al.. (2011). Structure-dependent Impairment of Intracellular Apolipoprotein E4 Trafficking and Its Detrimental Effects Are Rescued by Small-molecule Structure Correctors. Journal of Biological Chemistry. 286(19). 17217–17226. 84 indexed citations

14.

Chen, Hung-Kai, Zhaoping Liu, Anke Meyer‐Franke, et al.. (2011). Small Molecule Structure Correctors Abolish Detrimental Effects of Apolipoprotein E4 in Cultured Neurons. Journal of Biological Chemistry. 287(8). 5253–5266. 115 indexed citations

15.

Andrews‐Zwilling, Yaisa, Nga Bien‐Ly, Qin Xu, et al.. (2010). Apolipoprotein E4 Causes Age- and Tau-Dependent Impairment of GABAergic Interneurons, Leading to Learning and Memory Deficits in Mice. Journal of Neuroscience. 30(41). 13707–13717. 257 indexed citations

16.

Chen, Hung-Kai, Sara E. Dodson, R. Dennis Miranda, et al.. (2010). Apolipoprotein E4 Domain Interaction Mediates Detrimental Effects on Mitochondria and Is a Potential Therapeutic Target for Alzheimer Disease. Journal of Biological Chemistry. 286(7). 5215–5221. 154 indexed citations

17.

Xu, Qin, David Walker, Aubrey Bernardo, et al.. (2008). Intron-3 Retention/Splicing Controls Neuronal Expression of Apolipoprotein E in the CNS. Journal of Neuroscience. 28(6). 1452–1459. 90 indexed citations

18.

Li, Xiaokun, et al.. (2008). Retina Protective Effect of Acidic Fibroblast Growth Factor after Canceling Its Mitogenic Activity. Journal of Ocular Pharmacology and Therapeutics. 24(5). 445–452. 5 indexed citations

19.

Xiao, Yechen, et al.. (2006). Pro-apoptotic effect of cecropin AD on nasopharyngeal carcinoma cells. Chinese Medical Journal. 119(12). 1042–1046. 7 indexed citations

20.

Brecht, Walter J., Faith M. Harris, Shengjun Chang, et al.. (2004). Neuron-Specific Apolipoprotein E4 Proteolysis Is Associated with Increased Tau Phosphorylation in Brains of Transgenic Mice. Journal of Neuroscience. 24(10). 2527–2534. 323 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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