Kevin R. Lynch

21.5k total citations · 2 hit papers
202 papers, 16.0k citations indexed

About

Kevin R. Lynch is a scholar working on Molecular Biology, Cell Biology and Physiology. According to data from OpenAlex, Kevin R. Lynch has authored 202 papers receiving a total of 16.0k indexed citations (citations by other indexed papers that have themselves been cited), including 171 papers in Molecular Biology, 39 papers in Cell Biology and 28 papers in Physiology. Recurrent topics in Kevin R. Lynch's work include Sphingolipid Metabolism and Signaling (108 papers), Receptor Mechanisms and Signaling (41 papers) and Lipid Membrane Structure and Behavior (39 papers). Kevin R. Lynch is often cited by papers focused on Sphingolipid Metabolism and Signaling (108 papers), Receptor Mechanisms and Signaling (41 papers) and Lipid Membrane Structure and Behavior (39 papers). Kevin R. Lynch collaborates with scholars based in United States, Canada and France. Kevin R. Lynch's co-authors include Timothy L. Macdonald, Brian F. O’Dowd, M J Peach, Jeffrey K. Harrison, Volker Brinkmann, Michael D. Davis, Christopher E. Heise, Susan R. George, Tuan Nguyen and Diane L. Rosin and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Kevin R. Lynch

200 papers receiving 15.7k citations

Hit Papers

2 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors

2002 1.2k citations Michael D. Davis, Kevin R. Lynch et al. profile →
Regulation of learning and memory by meningeal immunity: a key role for IL-4

2010 599 citations Kevin R. Lynch et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Kevin R. Lynch United States	71	10.7k	2.5k	2.2k	2.2k	2.1k	202	16.0k
Thomas Franke United States	36	11.8k 1.1×	2.2k 0.9×	1.9k 0.9×	1.6k 0.7×	2.1k 1.0×	49	17.6k
Miles D. Houslay United Kingdom	88	19.8k 1.8×	3.4k 1.4×	4.4k 2.0×	1.7k 0.8×	1.8k 0.9×	414	25.6k
Joseph A. Beavo United States	72	16.6k 1.5×	3.8k 1.5×	2.9k 1.3×	1.0k 0.5×	2.2k 1.1×	169	22.2k
Hiroyoshi Hidaka Japan	59	9.3k 0.9×	1.9k 0.8×	2.6k 1.1×	1.7k 0.8×	1.0k 0.5×	326	14.3k
Thomas E. Willnow Germany	69	6.8k 0.6×	3.2k 1.3×	2.4k 1.1×	2.7k 1.2×	925 0.4×	179	14.7k
G. Stanley McKnight United States	76	10.9k 1.0×	1.6k 0.6×	3.8k 1.7×	1.3k 0.6×	883 0.4×	164	16.8k
Gary E. Shull United States	78	13.4k 1.2×	1.7k 0.7×	2.3k 1.0×	1.5k 0.7×	445 0.2×	213	17.6k
Salvatore DiMauro United States	87	23.0k 2.1×	3.2k 1.3×	2.9k 1.3×	1.6k 0.7×	470 0.2×	408	29.6k
António Zorzano Spain	78	14.6k 1.4×	5.8k 2.3×	1.8k 0.8×	3.1k 1.4×	996 0.5×	345	23.0k
Günter Schultz Germany	67	8.8k 0.8×	3.0k 1.2×	4.5k 2.0×	1.1k 0.5×	917 0.4×	148	15.3k

Countries citing papers authored by Kevin R. Lynch

Since Specialization

Citations

This map shows the geographic impact of Kevin R. Lynch's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kevin R. Lynch with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kevin R. Lynch more than expected).

Fields of papers citing papers by Kevin R. Lynch

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kevin R. Lynch. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kevin R. Lynch. The network helps show where Kevin R. Lynch may publish in the future.

Co-authorship network of co-authors of Kevin R. Lynch

This figure shows the co-authorship network connecting the top 25 collaborators of Kevin R. Lynch. A scholar is included among the top collaborators of Kevin R. Lynch based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kevin R. Lynch. Kevin R. Lynch is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kharel, Yugesh, et al.. (2024). Discovery of Potent, Orally Bioavailable Sphingosine-1-Phosphate Transporter (Spns2) Inhibitors. Journal of Medicinal Chemistry. 67(13). 11273–11295. 1 indexed citations

Kharel, Yugesh, et al.. (2023). 2-Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2). Journal of Medicinal Chemistry. 66(8). 5873–5891. 5 indexed citations

Huang, Tao, et al.. (2023). Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects. The Journal of General Physiology. 156(1). 2 indexed citations

Kharel, Yugesh, Tao Huang, Webster L. Santos, & Kevin R. Lynch. (2023). Assay of Sphingosine 1-phosphate Transporter Spinster Homolog 2 (Spns2) Inhibitors. SLAS DISCOVERY. 28(6). 284–287. 2 indexed citations

Tanaka, Shinji, Shuqiu Zheng, Yugesh Kharel, et al.. (2022). Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney. Science Translational Medicine. 14(658). eabj2681–eabj2681. 35 indexed citations

Fritzemeier, Russell G., et al.. (2022). Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors. Journal of Medicinal Chemistry. 65(11). 7656–7681. 16 indexed citations

Pashikanti, Srinath, Yugesh Kharel, Anne M. Brown, et al.. (2022). Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Derivatives Deliver Potent and Selective Analogues. PubMed. 2(5). 469–489. 5 indexed citations

Fritzemeier, Russell G., Yugesh Kharel, Anne M. Brown, et al.. (2020). Probing the substitution pattern of indole-based scaffold reveals potent and selective sphingosine kinase 2 inhibitors. European Journal of Medicinal Chemistry. 212. 113121–113121. 6 indexed citations

Kharel, Yugesh, Sayeh Agah, Tao Huang, et al.. (2018). Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors. PLoS ONE. 13(4). e0192179–e0192179. 6 indexed citations

10.

Kennedy, Perry, Ran Zhu, Tao Huang, et al.. (2011). Characterization of a Sphingosine 1-Phosphate Receptor Antagonist Prodrug. Journal of Pharmacology and Experimental Therapeutics. 338(3). 879–889. 29 indexed citations

11.

Sefcik, Lauren S., Caren E. Petrie Aronin, Soo Jung Shin, et al.. (2010). Selective Activation of Sphingosine 1-Phosphate Receptors 1 and 3 Promotes Local Microvascular Network Growth. Tissue Engineering Part A. 17(5-6). 617–629. 36 indexed citations

12.

Aronin, Caren E. Petrie, Lauren S. Sefcik, Sunil S. Tholpady, et al.. (2009). FTY720 Promotes Local Microvascular Network Formation and Regeneration of Cranial Bone Defects. Tissue Engineering Part A. 16(6). 1801–1809. 48 indexed citations

13.

Wamhoff, Brian R., Kevin R. Lynch, Timothy L. Macdonald, & Gary K. Owens. (2008). Sphingosine-1-Phosphate Receptor Subtypes Differentially Regulate Smooth Muscle Cell Phenotype. Arteriosclerosis Thrombosis and Vascular Biology. 28(8). 1454–1461. 82 indexed citations

14.

Sánchez, Teresa, et al.. (2008). Induction of Antiproliferative Connective Tissue Growth Factor Expression in Wilms' Tumor Cells by Sphingosine-1-Phosphate Receptor 2. Molecular Cancer Research. 6(10). 1649–1656. 56 indexed citations

15.

Hughes, J., Suseela Srinivasan, Kevin R. Lynch, et al.. (2008). Sphingosine-1-Phosphate Induces an Antiinflammatory Phenotype in Macrophages. Circulation Research. 102(8). 950–958. 208 indexed citations

16.

Foss, Frank W., Jeremy J. Clemens, Michael D. Davis, et al.. (2005). Synthesis, stability, and implications of phosphothioate agonists of sphingosine-1-phosphate receptors. Bioorganic & Medicinal Chemistry Letters. 15(20). 4470–4474. 21 indexed citations

17.

Figueroa, David J., Richard Breyer, Stacia Kargman, et al.. (2001). Expression of the Cysteinyl Leukotriene 1 Receptor in Normal Human Lung and Peripheral Blood Leukocytes. American Journal of Respiratory and Critical Care Medicine. 163(1). 226–233. 225 indexed citations

18.

Lee, Dennis K., Tuan Nguyen, Kevin R. Lynch, et al.. (2001). Discovery and mapping of ten novel G protein-coupled receptor genes. Gene. 275(1). 83–91. 170 indexed citations

19.

Im, Dong‐Soon, Anne R. Ungar, & Kevin R. Lynch. (2000). Characterization of a Zebrafish (Danio rerio) Sphingosine 1-Phosphate Receptor Expressed in the Embryonic Brain. Biochemical and Biophysical Research Communications. 279(1). 139–143. 16 indexed citations

20.

Goetzl, Edward J. & Kevin R. Lynch. (2000). Lysophospholipids and eicosanoids in biology and pathophysiology. 17 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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