Carlos Cruchaga

62.3k total citations · 2 hit papers
214 papers, 8.0k citations indexed

About

Carlos Cruchaga is a scholar working on Physiology, Molecular Biology and Neurology. According to data from OpenAlex, Carlos Cruchaga has authored 214 papers receiving a total of 8.0k indexed citations (citations by other indexed papers that have themselves been cited), including 105 papers in Physiology, 82 papers in Molecular Biology and 45 papers in Neurology. Recurrent topics in Carlos Cruchaga's work include Alzheimer's disease research and treatments (94 papers), Dementia and Cognitive Impairment Research (45 papers) and Bioinformatics and Genomic Networks (35 papers). Carlos Cruchaga is often cited by papers focused on Alzheimer's disease research and treatments (94 papers), Dementia and Cognitive Impairment Research (45 papers) and Bioinformatics and Genomic Networks (35 papers). Carlos Cruchaga collaborates with scholars based in United States, Spain and United Kingdom. Carlos Cruchaga's co-authors include Alison Goate, John C. Morris, Celeste M. Karch, David M. Holtzman, Anne M. Fagan, Bruno A. Benítez, Kelly R. Bales, Oscar Harari, Yuetiva Deming and Randall J. Bateman and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Carlos Cruchaga

198 papers receiving 7.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance

2011 887 citations Anne M. Fagan, John C. Morris et al. Science Translational Medicine profile →
Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease

2023 180 citations Tammie L.S. Benzinger, David M. Holtzman et al. Science Translational Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Carlos Cruchaga United States	45	4.0k	2.7k	2.6k	1.3k	1.2k	214	8.0k
Daniela Galimberti Italy	59	3.8k 1.0×	2.7k 1.0×	3.5k 1.3×	2.1k 1.7×	1.5k 1.3×	354	11.6k
Takahisa Kanekiyo United States	49	4.9k 1.2×	2.3k 0.8×	3.4k 1.3×	819 0.6×	1.1k 0.9×	107	9.2k
James J. Lah United States	59	4.5k 1.1×	1.7k 0.6×	4.1k 1.6×	1.0k 0.8×	1.2k 1.0×	204	9.4k
C. Dirk Keene United States	46	2.5k 0.6×	2.0k 0.7×	3.0k 1.2×	1.8k 1.4×	743 0.6×	234	8.5k
Donna M. Wilcock United States	50	5.5k 1.4×	3.9k 1.4×	2.4k 0.9×	923 0.7×	825 0.7×	158	9.2k
Robert Veerhuis Netherlands	49	3.5k 0.9×	2.8k 1.0×	2.3k 0.9×	676 0.5×	544 0.4×	126	7.0k
Bruce T. Lamb United States	53	5.6k 1.4×	4.6k 1.7×	3.6k 1.4×	809 0.6×	650 0.5×	130	11.4k
Rita Guerreiro United Kingdom	40	2.6k 0.6×	1.7k 0.6×	1.8k 0.7×	1.9k 1.5×	494 0.4×	130	5.6k
Robert E. Mrak United States	51	3.8k 0.9×	3.4k 1.2×	3.1k 1.2×	1.4k 1.1×	638 0.5×	143	9.4k
Lih‐Fen Lue United States	44	3.4k 0.8×	2.8k 1.0×	1.8k 0.7×	1.1k 0.9×	429 0.4×	79	6.7k

Countries citing papers authored by Carlos Cruchaga

Since Specialization

Citations

This map shows the geographic impact of Carlos Cruchaga's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Carlos Cruchaga with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Carlos Cruchaga more than expected).

Fields of papers citing papers by Carlos Cruchaga

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Carlos Cruchaga. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Carlos Cruchaga. The network helps show where Carlos Cruchaga may publish in the future.

Co-authorship network of co-authors of Carlos Cruchaga

This figure shows the co-authorship network connecting the top 25 collaborators of Carlos Cruchaga. A scholar is included among the top collaborators of Carlos Cruchaga based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Carlos Cruchaga. Carlos Cruchaga is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Cruchaga, Carlos, et al.. (2025). Plasma NfL and cognitive functioning in older adults: The moderating role of HDL cholesterol. Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring. 17(4). e70205–e70205.

Chemparathy, Augustine, Yann Le Guen, Yi Zeng, et al.. (2024). A 3′UTR Insertion Is a Candidate Causal Variant at the TMEM106B Locus Associated With Increased Risk for FTLD-TDP. Neurology Genetics. 10(1). e200124–e200124. 5 indexed citations

Wang, Qing, Suzanne E. Schindler, Gengsheng Chen, et al.. (2024). Investigating White Matter Neuroinflammation in Alzheimer Disease Using Diffusion-Based Neuroinflammation Imaging. Neurology. 102(4). e208013–e208013. 12 indexed citations

Ye, Hui, Carl Grant Mangleburg, Timothy Wu, et al.. (2023). Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity. PLoS Genetics. 19(5). e1010760–e1010760. 7 indexed citations

Wang, Lihua, Niko-Petteri Nykänen, Daniel Western, et al.. (2023). Proteo‐genomics of soluble TREM2 in cerebrospinal fluid provides novel insights for TREM2 biology and identifies novel modulators for Alzheimer’s disease. Alzheimer s & Dementia. 19(S12). 1 indexed citations

Beric, Aleksandra, Muhammad Ali, María Victoria Fernández, et al.. (2023). Cell-free RNA signatures predict Alzheimer’s disease. iScience. 26(12). 108534–108534. 3 indexed citations

Timsina, Jigyasha, Muhammad Ali, Lihua Wang, et al.. (2023). Harmonization of CSF and imaging biomarkers in Alzheimer's disease: Need and practical applications for genetics studies and preclinical classification. Neurobiology of Disease. 190. 106373–106373. 7 indexed citations

Wisch, Julie K., Omar H. Butt, Brian A. Gordon, et al.. (2022). Proteomic clusters underlie heterogeneity in preclinical Alzheimer’s disease progression. Brain. 146(7). 2944–2956. 5 indexed citations

Qin, Wei, Aihong Zhou, Xiumei Zuo, et al.. (2021). Exome sequencing revealed PDE11A as a novel candidate gene for early-onset Alzheimer’s disease. Human Molecular Genetics. 30(9). 811–822. 10 indexed citations

10.

Castillo-Barnés, Diego, Li Su, Javier Ramı́rez, et al.. (2020). Autosomal dominantly inherited alzheimer disease: Analysis of genetic subgroups by machine learning. Information Fusion. 58. 153–167. 15 indexed citations

11.

Cignarella, Francesca, Fabia Filipello, Bryan Bollman, et al.. (2020). TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis. Acta Neuropathologica. 140(4). 513–534. 257 indexed citations

12.

Ewers, Michael, Nicolai Franzmeier, Marc Suárez‐Calvet, et al.. (2019). Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer’s disease. Science Translational Medicine. 11(507). 201 indexed citations

13.

Suárez‐Calvet, Marc, Estrella Morenas‐Rodríguez, Gernot Kleinberger, et al.. (2019). Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology. Molecular Neurodegeneration. 14(1). 1–1. 185 indexed citations

14.

Deming, Yuetiva, Kathleen Black, David Carrell, et al.. (2016). Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40. BMC Neurology. 16(1). 217–217. 12 indexed citations

15.

Kober, Daniel L., Jennifer Alexander‐Brett, Celeste M. Karch, et al.. (2016). Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms. eLife. 5. 163 indexed citations

16.

Louwersheimer, Eva, Alfredo Ramı́rez, Carlos Cruchaga, et al.. (2014). The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease. Neurobiology of Aging. 36(3). 1605.e13–1605.e20. 29 indexed citations

17.

Harari, Oscar, Carlos Cruchaga, John S. K. Kauwe, et al.. (2014). Phosphorylated Tau-Aβ42 Ratio as a Continuous Trait for Biomarker Discovery for Early-Stage Alzheimer’s Disease in Multiplex Immunoassay Panels of Cerebrospinal Fluid. Biological Psychiatry. 75(9). 723–731. 69 indexed citations

18.

Peterson, David B., Chris Corcoran, Carlos Cruchaga, et al.. (2013). Variants in PPP3R1 and MAPT are associated with more rapid functional decline in Alzheimer's disease: The Cache County Dementia Progression Study. Alzheimer s & Dementia. 10(3). 366–371. 28 indexed citations

19.

Kauwe, John, Carlos Cruchaga, Celeste M. Karch, et al.. (2011). Fine Mapping of Genetic Variants in BIN1, CLU, CR1 and PICALM for Association with Cerebrospinal Fluid Biomarkers for Alzheimer's Disease. PLoS ONE. 6(2). e15918–e15918. 45 indexed citations

20.

Cruchaga, Carlos, et al.. (1996). Cáncer gástrico precoz. Revista Chilena de Cirugía. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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