Alexandra C. Newton

25.0k total citations · 9 hit papers
195 papers, 20.5k citations indexed

About

Alexandra C. Newton is a scholar working on Molecular Biology, Cell Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Alexandra C. Newton has authored 195 papers receiving a total of 20.5k indexed citations (citations by other indexed papers that have themselves been cited), including 178 papers in Molecular Biology, 43 papers in Cell Biology and 16 papers in Cellular and Molecular Neuroscience. Recurrent topics in Alexandra C. Newton's work include Protein Kinase Regulation and GTPase Signaling (115 papers), PI3K/AKT/mTOR signaling in cancer (50 papers) and Receptor Mechanisms and Signaling (35 papers). Alexandra C. Newton is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (115 papers), PI3K/AKT/mTOR signaling in cancer (50 papers) and Receptor Mechanisms and Signaling (35 papers). Alexandra C. Newton collaborates with scholars based in United States, United Kingdom and Canada. Alexandra C. Newton's co-authors include Alex Toker, Roger Y. Tsien, Jonathan D. Violin, Tianyan Gao, David A. Zacharias, John Brognard, Frank B. Furnari, Maya T. Kunkel, Lisa M. Keranen and Jeffrey W. Orr and has published in prestigious journals such as Science, Cell and Chemical Reviews.

In The Last Decade

Alexandra C. Newton

195 papers receiving 20.2k citations

Hit Papers

Partitioning of Lipid-Modified Monomeric GFPs into Membra... 1995 2026 2005 2015 2002 1995 2001 1997 2005 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells
    2002 1.9k citations David A. Zacharias, Jonathan D. Violin et al. Science profile →
  2. Protein Kinase C: Structure, Function, and Regulation
    1995 1.4k citations Alexandra C. Newton Journal of Biological Chemistry profile →
  3. Protein Kinase C:  Structural and Spatial Regulation by Phosphorylation, Cofactors, and Macromolecular Interactions
    2001 813 citations Alexandra C. Newton profile →
  4. Regulation of protein kinase C
    1997 803 citations Alexandra C. Newton profile →
  5. PHLPP: A Phosphatase that Directly Dephosphorylates Akt, Promotes Apoptosis, and Suppresses Tumor Growth
    2005 725 citations Tianyan Gao, Alexandra C. Newton et al. Molecular Cell profile →
  6. Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm
    2003 649 citations Alexandra C. Newton Biochemical Journal profile →
  7. Protein kinase C isozymes and the regulation of diverse cell responses
    2000 632 citations Alexandra C. Newton et al. profile →
  8. Regulation of protein kinase C ζ by PI 3-kinase and PDK-1
    1998 548 citations Alexandra C. Newton, Alex Toker et al. profile →
  9. A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C
    2003 460 citations Jonathan D. Violin, Jin Zhang et al. The Journal of Cell Biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Alexandra C. Newton United States 72 16.4k 3.6k 2.2k 1.7k 1.6k 195 20.5k
Naoki Mochizuki Japan 64 10.4k 0.6× 4.5k 1.3× 1.9k 0.9× 1.4k 0.8× 1.5k 0.9× 250 17.0k
Susan S. Taylor United States 98 29.1k 1.8× 5.6k 1.6× 2.5k 1.1× 3.5k 2.1× 1.5k 0.9× 462 35.7k
David L. Brautigan United States 70 12.4k 0.8× 3.6k 1.0× 1.6k 0.7× 1.8k 1.1× 1.2k 0.7× 249 16.5k
Wouter H. Moolenaar Netherlands 84 18.7k 1.1× 5.6k 1.6× 2.7k 1.2× 1.7k 1.0× 2.0k 1.2× 198 23.4k
Jean‐Claude Martinou Switzerland 79 22.0k 1.3× 2.3k 0.6× 3.8k 1.8× 2.4k 1.4× 2.6k 1.6× 194 27.9k
Luca Scorrano Italy 81 25.1k 1.5× 4.2k 1.2× 2.7k 1.2× 1.1k 0.6× 1.9k 1.2× 186 31.7k
Rony Seger Israel 70 14.9k 0.9× 3.1k 0.9× 2.7k 1.2× 4.2k 2.5× 2.5k 1.5× 206 22.2k
Ian G. Macara United States 83 17.5k 1.1× 7.2k 2.0× 1.5k 0.7× 2.0k 1.2× 1.4k 0.9× 208 23.2k
Masatoshi Hagiwara Japan 62 11.6k 0.7× 1.5k 0.4× 2.3k 1.1× 1.5k 0.9× 1.2k 0.7× 301 16.4k
Alfred Wittinghofer Germany 96 25.9k 1.6× 8.3k 2.3× 2.1k 1.0× 3.1k 1.9× 1.6k 1.0× 296 31.2k

Countries citing papers authored by Alexandra C. Newton

Since Specialization
Citations

This map shows the geographic impact of Alexandra C. Newton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alexandra C. Newton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alexandra C. Newton more than expected).

Fields of papers citing papers by Alexandra C. Newton

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alexandra C. Newton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alexandra C. Newton. The network helps show where Alexandra C. Newton may publish in the future.

Co-authorship network of co-authors of Alexandra C. Newton

This figure shows the co-authorship network connecting the top 25 collaborators of Alexandra C. Newton. A scholar is included among the top collaborators of Alexandra C. Newton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alexandra C. Newton. Alexandra C. Newton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Newton, Alexandra C., et al.. (2022). Two Sides of the Same Coin: Protein Kinase C γ in Cancer and Neurodegeneration. Frontiers in Cell and Developmental Biology. 10. 929510–929510. 7 indexed citations
2.
Baffi, Timothy R., Gema Lordén, Jacob M. Wozniak, et al.. (2021). mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif. Science Signaling. 14(678). 72 indexed citations
3.
Zhou, Xin, Olivia Molinar‐Inglis, Maya T. Kunkel, et al.. (2020). Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus. Nature Communications. 11(1). 6088–6088. 38 indexed citations
4.
Kajimoto, Taketoshi, Irene S. Tobias, Taro Okada, et al.. (2019). Activation of atypical protein kinase C by sphingosine 1-phosphate revealed by an aPKC-specific activity reporter. Science Signaling. 12(562). 44 indexed citations
5.
Stender, Joshua D., Gema Lordén, Satoshi Uchiyama, et al.. (2019). PHLPP1 counter-regulates STAT1-mediated inflammatory signaling. eLife. 8. 27 indexed citations
6.
Newton, Alexandra C.. (2018). Protein kinase C: perfectly balanced. Critical Reviews in Biochemistry and Molecular Biology. 53(2). 208–230. 219 indexed citations
7.
Huang, Liang‐Chin, Karen Ross, Timothy R. Baffi, et al.. (2018). Integrative annotation and knowledge discovery of kinase post-translational modifications and cancer-associated mutations through federated protein ontologies and resources. Scientific Reports. 8(1). 23 indexed citations
8.
McSkimming, Daniel, Timothy R. Baffi, Dominic P. Byrne, et al.. (2016). KinView: a visual comparative sequence analysis tool for integrated kinome research. Molecular BioSystems. 12(12). 3651–3665. 35 indexed citations
9.
Tobias, Irene S., Manuel Kaulich, Peter K. Kim, et al.. (2015). Protein kinase Cζ exhibits constitutive phosphorylation and phosphatidylinositol-3,4,5-triphosphate-independent regulation. Biochemical Journal. 473(4). 509–523. 27 indexed citations
10.
Patterson, Scott J., Jonathan M. Han, Rosa García, et al.. (2011). Cutting Edge: PHLPP Regulates the Development, Function, and Molecular Signaling Pathways of Regulatory T Cells. The Journal of Immunology. 186(10). 5533–5537. 58 indexed citations
11.
Kunkel, Maya T. & Alexandra C. Newton. (2010). Calcium Transduces Plasma Membrane Receptor Signals to Produce Diacylglycerol at Golgi Membranes. Journal of Biological Chemistry. 285(30). 22748–22752. 32 indexed citations
12.
Brognard, John, Emma Sierecki, Tianyan Gao, & Alexandra C. Newton. (2007). PHLPP and a Second Isoform, PHLPP2, Differentially Attenuate the Amplitude of Akt Signaling by Regulating Distinct Akt Isoforms. Molecular Cell. 25(6). 917–931. 469 indexed citations
13.
Gao, Tianyan, John Brognard, & Alexandra C. Newton. (2007). The Phosphatase PHLPP Controls the Cellular Levels of Protein Kinase C. Journal of Biological Chemistry. 283(10). 6300–6311. 163 indexed citations
14.
Kunkel, Maya T., Alex Toker, Roger Y. Tsien, & Alexandra C. Newton. (2006). Calcium-dependent Regulation of Protein Kinase D Revealed by a Genetically Encoded Kinase Activity Reporter. Journal of Biological Chemistry. 282(9). 6733–6742. 89 indexed citations
15.
Violin, Jonathan D., Jin Zhang, Roger Y. Tsien, & Alexandra C. Newton. (2003). A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C. The Journal of Cell Biology. 161(5). 899–909. 460 indexed citations breakdown →
16.
Zacharias, David A., Jonathan D. Violin, Alexandra C. Newton, & Roger Y. Tsien. (2002). Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells. Science. 296(5569). 913–916. 1851 indexed citations breakdown →
17.
Edwards, A. & Alexandra C. Newton. (1997). Phosphorylation at Conserved Carboxyl-terminal Hydrophobic Motif Regulates the Catalytic and Regulatory Domains of Protein Kinase C. Journal of Biological Chemistry. 272(29). 18382–18390. 134 indexed citations
18.
Udovichenko, Igor P., Alexandra C. Newton, & David S. Williams. (1997). Contribution of Protein Kinase C to the Phosphorylation of Rhodopsin in Intact Retinas. Journal of Biological Chemistry. 272(12). 7952–7959. 17 indexed citations
19.
Williams, David S., et al.. (1995). Kinetics and Localization of the Phosphorylation of Rhodopsin by Protein Kinase C. Journal of Biological Chemistry. 270(12). 6710–6717. 27 indexed citations
20.
Fisher, Charles R., James J. Childress, Alissa J. Arp, et al.. (1988). Physiology, morphology, and biochemical composition of Riftia pachyptila at Rose Garden in 1985. Deep Sea Research Part A Oceanographic Research Papers. 35(10-11). 1745–1758. 52 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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