John Brognard

6.1k total citations · 1 hit paper
50 papers, 4.5k citations indexed

About

John Brognard is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, John Brognard has authored 50 papers receiving a total of 4.5k indexed citations (citations by other indexed papers that have themselves been cited), including 44 papers in Molecular Biology, 15 papers in Oncology and 9 papers in Cancer Research. Recurrent topics in John Brognard's work include PI3K/AKT/mTOR signaling in cancer (19 papers), Melanoma and MAPK Pathways (10 papers) and Protein Kinase Regulation and GTPase Signaling (8 papers). John Brognard is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (19 papers), Melanoma and MAPK Pathways (10 papers) and Protein Kinase Regulation and GTPase Signaling (8 papers). John Brognard collaborates with scholars based in United States, United Kingdom and Poland. John Brognard's co-authors include Phillip A. Dennis, Alexandra C. Newton, Amy S. Clark, Yucheng Ni, Tianyan Gao, Tony Hunter, Emma Sierecki, Kip A. West, Curtis C. Harris and Ilona Linnoila and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

John Brognard

49 papers receiving 4.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation.

2001 793 citations John Brognard, Amy S. Clark et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
John Brognard United States	25	3.7k	1.0k	658	464	358	50	4.5k
Jörg Bäsecke Germany	22	3.0k 0.8×	1.2k 1.2×	669 1.0×	338 0.7×	460 1.3×	34	4.4k
William H. Chappell United States	27	2.7k 0.7×	1.3k 1.3×	695 1.1×	418 0.9×	466 1.3×	41	4.0k
Fumin Chang United States	17	2.3k 0.6×	964 1.0×	527 0.8×	302 0.7×	389 1.1×	26	3.5k
Gary G. Chiang United States	23	2.9k 0.8×	666 0.7×	900 1.4×	402 0.9×	202 0.6×	47	3.8k
Amardeep S. Dhillon Australia	25	3.6k 1.0×	1.1k 1.1×	740 1.1×	325 0.7×	683 1.9×	44	4.9k
Camilla Evangelisti Italy	38	4.5k 1.2×	1.4k 1.4×	860 1.3×	386 0.8×	534 1.5×	90	6.4k
Chifumi Kitanaka Japan	40	2.8k 0.7×	1.2k 1.2×	794 1.2×	557 1.2×	516 1.4×	116	4.7k
Hiroshi Yasui Japan	31	3.0k 0.8×	1.3k 1.3×	415 0.6×	350 0.8×	419 1.2×	141	4.7k
Benjamin D. Hopkins United States	26	3.0k 0.8×	979 1.0×	940 1.4×	576 1.2×	314 0.9×	44	4.5k
Donatella Del Bufalo Italy	42	3.0k 0.8×	1.4k 1.4×	1.0k 1.6×	350 0.8×	228 0.6×	133	4.7k

Countries citing papers authored by John Brognard

Since Specialization

Citations

This map shows the geographic impact of John Brognard's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Brognard with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Brognard more than expected).

Fields of papers citing papers by John Brognard

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Brognard. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Brognard. The network helps show where John Brognard may publish in the future.

Co-authorship network of co-authors of John Brognard

This figure shows the co-authorship network connecting the top 25 collaborators of John Brognard. A scholar is included among the top collaborators of John Brognard based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John Brognard. John Brognard is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Paulo, João A., Christina B. Schroeter, Saima Siddiqi, et al.. (2025). CRISPR screens and quantitative proteomics reveal remodeling of the aryl hydrocarbon receptor–driven proteome through PARP7 activity. Proceedings of the National Academy of Sciences. 122(24). e2424985122–e2424985122. 2 indexed citations

Bergman, K., Eric Lindberg, Carolyn C. Woodroofe, et al.. (2025). Discovery of potent and selective PROTACs for the protein kinase LZK for the treatment of head and neck cancer. Journal of Biological Chemistry. 301(5). 108452–108452. 1 indexed citations

Connis, Nick, Jinhee Chang, Amol C. Shetty, et al.. (2024). TNIK Inhibition Sensitizes TNIK-Overexpressing Lung Squamous Cell Carcinoma to Radiotherapy. Molecular Cancer Therapeutics. 23(8). 1201–1211. 3 indexed citations

Sabbasani, Venkata R., Pedro Torres‐Ayuso, Katarzyna Wróbel, et al.. (2024). Selective Degradation of MLK3 by a Novel CEP1347-VHL-02 PROTAC Compound Limits the Oncogenic Potential of TNBC. Journal of Medicinal Chemistry. 67(17). 15012–15028. 5 indexed citations

Torres‐Ayuso, Pedro, Meghri Katerji, Venkata R. Sabbasani, et al.. (2023). PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer. Cell chemical biology. 31(2). 326–337.e11. 6 indexed citations

Torres‐Ayuso, Pedro & John Brognard. (2022). Degraders: The Ultimate Weapon Against Amplified Driver Kinases in Cancer. Molecular Pharmacology. 101(4). 191–200. 10 indexed citations

Torres‐Ayuso, Pedro, Katherine M. Nyswaner, Daniel A. Ritt, et al.. (2021). TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin. Cancer Discovery. 11(6). 1411–1423. 38 indexed citations

Brognard, John, et al.. (2021). New Therapeutic Opportunities for the Treatment of Squamous Cell Carcinomas: A Focus on Novel Driver Kinases. International Journal of Molecular Sciences. 22(6). 2831–2831. 8 indexed citations

Marusiak, Anna A., Michał Łaźniewski, Hanna Kędzierska, et al.. (2018). Upregulation of MLK4 promotes migratory and invasive potential of breast cancer cells. Oncogene. 38(15). 2860–2875. 17 indexed citations

10.

Trotter, Eleanor W., et al.. (2017). Survival of Head and Neck Cancer Cells Relies upon LZK Kinase-Mediated Stabilization of Mutant p53. Cancer Research. 77(18). 4961–4972. 24 indexed citations

11.

Newton, Alexandra C. & John Brognard. (2017). Reversing the Paradigm: Protein Kinase C as a Tumor Suppressor. Trends in Pharmacological Sciences. 38(5). 438–447. 81 indexed citations

12.

Antal, Corina E., Andrew Hudson, Emily L. Kang, et al.. (2015). Cancer-Associated Protein Kinase C Mutations Reveal Kinase’s Role as Tumor Suppressor. Cell. 160(3). 489–502. 263 indexed citations

13.

Hudson, Andrew, Tim Yates, Yaoyong Li, et al.. (2014). Discrepancies in Cancer Genomic Sequencing Highlight Opportunities for Driver Mutation Discovery. Cancer Research. 74(22). 6390–6396. 27 indexed citations

14.

Zhang, You-Wei, John Brognard, Zhongsheng You, et al.. (2009). The F Box Protein Fbx6 Regulates Chk1 Stability and Cellular Sensitivity to Replication Stress. Molecular Cell. 35(4). 442–453. 146 indexed citations

15.

Brognard, John & Alexandra C. Newton. (2008). PHLiPPing the switch on Akt and protein kinase C signaling. Trends in Endocrinology and Metabolism. 19(6). 223–230. 151 indexed citations

16.

Brognard, John, Emma Sierecki, Tianyan Gao, & Alexandra C. Newton. (2007). PHLPP and a Second Isoform, PHLPP2, Differentially Attenuate the Amplitude of Akt Signaling by Regulating Distinct Akt Isoforms. Molecular Cell. 25(6). 917–931. 469 indexed citations

17.

Gao, Tianyan, John Brognard, & Alexandra C. Newton. (2007). The Phosphatase PHLPP Controls the Cellular Levels of Protein Kinase C. Journal of Biological Chemistry. 283(10). 6300–6311. 163 indexed citations

18.

West, Kip A., Ilona Linnoila, John Brognard, et al.. (2004). Tobacco Carcinogen-Induced Cellular Transformation Increases Akt Activation In Vitro and In Vivo. CHEST Journal. 125(5). 101S–102S. 10 indexed citations

19.

West, Kip A., John Brognard, Amy S. Clark, et al.. (2003). Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells. Journal of Clinical Investigation. 111(1). 81–90. 437 indexed citations

20.

Kozikowski, Alan P., Haiying Sun, John Brognard, & Phillip A. Dennis. (2003). Novel PI Analogues Selectively Block Activation of the Pro-survival Serine/Threonine Kinase Akt. Journal of the American Chemical Society. 125(5). 1144–1145. 179 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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