Jonathan D. Violin

11.6k citations

53 papers · 9.5k indexed · 7 hit papers · h-index 44

Impact in

Cellular and Molecular Neuroscience top 0.2%
- Neuropeptides and Animal Physiology
- Neuroscience and Neuropharmacology Research
Molecular Biology top 0.5%
- Receptor Mechanisms and Signaling
- Protein Kinase Regulation and GTPase Signaling
- Pharmacological Receptor Mechanisms and Effects

Papers in

Cellular and Molecular Neuroscience 28
- Neuropeptides and Animal Physiology 27
Molecular Biology 48
- Receptor Mechanisms and Signaling 42
- Protein Kinase Regulation and GTPase Signaling 9
- Pharmacological Receptor Mechanisms and Effects 5

Co-authors: Robert J. Lefkowitz Alexandra C. Newton Roger Y. Tsien David A. Zacharias Erin J. Whalen Scott M. DeWire Michael W. Lark David G. Soergel
Journals: Journal of Biological Chemistry (7 papers)Proceedings of the National Academy of Sciences (5 papers)Molecular Pharmacology (4 papers)Journal of Pharmacology and Experimental Therapeutics (4 papers)Journal of Clinical Investigation (2 papers)
Partner nations: United States Italy Netherlands

In The Last Decade

Jonathan D. Violin

53 papers receiving 9.3k citations

Hit Papers

7 papers align trajectories log scale

A G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with Morphine 2013 · 502 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2013 Journal of Pharmacology and Experimental Therapeutics
2011 Molecular Pharmacology
2007 Journal of Clinical Investigation
2007 Proceedings of the National Academy of Sciences
2007 Trends in Pharmacological Sciences
2003 The Journal of Cell Biology
2002 Science

Peers

Countries citing papers authored by Jonathan D. Violin

Since Specialization

Citations

This map shows the geographic impact of Jonathan D. Violin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jonathan D. Violin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jonathan D. Violin more than expected).

Fields of papers citing papers by Jonathan D. Violin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jonathan D. Violin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jonathan D. Violin. The network helps show where Jonathan D. Violin may publish in the future.

Co-authors

The 25 scholars most cited alongside Jonathan D. Violin, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jonathan D. Violin Line = papers co-authored together Jonathan D. Violin links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Heart Failure Therapeutics on the Basis of a Biased Ligand of the Angiotensin-2 Type 1 Receptor JACC Heart Failure ·G. Michael Felker, Javed Butler, Sean P. Collins, Gad Cotter, Beth A. Davison, Justin A. Ezekowitz, Gerasimos Filippatos, Phillip D. Levy, Marco Metra, Piotr Ponikowski, David G. Soergel, John R. Teerlink, Jonathan D. Violin, Adriaan A. Voors, Peter S. Pang	2015	62
2	Biased agonism of the μ-opioid receptor by TRV130 increases analgesia and reduces on-target adverse effects versus morphine: A randomized, double-blind, placebo-controlled, crossover study in healthy volunteers Pain ·David G. Soergel, Ruth Ann Subach, Nancy Burnham, Michael W. Lark, Ian E. James, Brian M. Sadler, Franck Skobieranda, Jonathan D. Violin, Lynn R. Webster	2014	220
3	Biased ligands at G-protein-coupled receptors: promise and progress Trends in Pharmacological Sciences ·Jonathan D. Violin, Aimee L. Crombie, David G. Soergel, Michael W. Lark	2014	290
4	Divergent Transducer-specific Molecular Efficacies Generate Biased Agonism at a G Protein-coupled Receptor (GPCR) Journal of Biological Chemistry ·Ryan T. Strachan, Jin‐Peng Sun, David H. Rominger, Jonathan D. Violin, Seungkirl Ahn, A. Thomsen, Xiao Zhu, Andrew B. Kleist, Tommaso Costa, Robert J. Lefkowitz	2014	101
5	Biased ligands: pathway validation for novel GPCR therapeutics Current Opinion in Pharmacology ·David H. Rominger, Conrad L. Cowan, William Gowen-MacDonald, Jonathan D. Violin	2014	25
6	Intramolecular Conformational Changes Optimize Protein Kinase C Signaling Chemistry & Biology ·Corina E. Antal, Jonathan D. Violin, Maya T. Kunkel, Søs Skovsø, Alexandra C. Newton	2014	48
7	First Clinical Experience with TRV027: Pharmacokinetics and Pharmacodynamics in Healthy Volunteers The Journal of Clinical Pharmacology ·David G. Soergel, Ruth Ann Subach, Conrad L. Cowan, Jonathan D. Violin, Michael W. Lark	2013	68
8	β-Arrestin-biased AT1R stimulation promotes cell survival during acute cardiac injury American Journal of Physiology-Heart and Circulatory Physiology ·Ki-Seok Kim, Dennis Abraham, Barbara Williams, Jonathan D. Violin, Lan Mao, Howard A. Rockman	2012	99
9	β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice Journal of Clinical Investigation ·Robert W. Walters, Arun K. Shukla, Jeffrey J. Kovacs, Jonathan D. Violin, Scott M. DeWire, Qi Win Ting, A Maumary, Michael J. Muehlbauer, Erin J. Whalen, Robert J. Lefkowitz	2009	193
10	β-Arrestin Mediates β1-Adrenergic Receptor-Epidermal Growth Factor Receptor Interaction and Downstream Signaling Journal of Biological Chemistry ·Douglas G. Tilley, Il‐man Kim, Priyesh Patel, Jonathan D. Violin, Howard A. Rockman	2009	85
11	Pharmacological Characterization of Membrane-Expressed Human Trace Amine-Associated Receptor 1 (TAAR1) by a Bioluminescence Resonance Energy Transfer cAMP Biosensor Molecular Pharmacology ·Larry S. Barak, Ali Salahpour, Xiao-Dong Zhang, Bernard Masri, Tatyana D. Sotnikova, Amy J. Ramsey, Jonathan D. Violin, R.J. Lefkowitz, Marc G. Caron, Raul R. Gainetdinov	2008	120
12	A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling Proceedings of the National Academy of Sciences ·James W. Wisler, Scott M. DeWire, Erin J. Whalen, Jonathan D. Violin, Matthew T. Drake, Seungkirl Ahn, Sudha K. Shenoy, Robert J. Lefkowitz Hit paper breakdown →	2007	477
13	β-Arrestin–mediated β1-adrenergic receptor transactivation of the EGFR confers cardioprotection Journal of Clinical Investigation ·Takahisa Noma, Anthony Lemaire, Sathyamangla V. Naga Prasad, Liza Barki‐Harrington, Douglas G. Tilley, 大沼眞廣, Philippe Le Corvoisier, Jonathan D. Violin, Huijun Wei, Robert J. Lefkowitz, Howard A. Rockman Hit paper breakdown →	2007	360
14	Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2 Cell ·Erin J. Whalen, Matthew W. Foster, Akio Matsumoto, Kentaro Ozawa, Jonathan D. Violin, Loretta G. Que, Karin Garmer, Moran Benhar, Janelle R. Keys, Howard A. Rockman, Walter J. Koch, Yehia Daaka, Robert J. Lefkowitz, Jonathan S. Stamler	2007	237
15	G Protein-coupled Receptor Kinase and β-Arrestin-mediated Desensitization of the Angiotensin II Type 1A Receptor Elucidated by Diacylglycerol Dynamics Journal of Biological Chemistry ·Jonathan D. Violin, Scott M. DeWire, William G. Barnes, Robert J. Lefkowitz	2006	68
16	G-protein-coupled Receptor Kinase Specificity for β-Arrestin Recruitment to the β2-Adrenergic Receptor Revealed by Fluorescence Resonance Energy Transfer Journal of Biological Chemistry ·Jonathan D. Violin, Xiu-Rong Ren, Robert J. Lefkowitz	2006	109
17	β-Arrestin 1 and Gαq/11 Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation Journal of Biological Chemistry ·William G. Barnes, Éric Reiter, Jonathan D. Violin, Xiu-Rong Ren, Graeme Milligan, Robert J. Lefkowitz	2004	161
18	A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C The Journal of Cell Biology ·Jonathan D. Violin, Jin Zhang, Roger Y. Tsien, Alexandra C. Newton Hit paper breakdown →	2003	460
19	Pathway Illuminated: Visualizing Protein Kinase C Signaling IUBMB Life ·Jonathan D. Violin, Alexandra C. Newton	2003	39
20	Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells Science ·David A. Zacharias, Jonathan D. Violin, Alexandra C. Newton, Roger Y. Tsien Hit paper breakdown →	2002	1851

About Jonathan D. Violin

Jonathan D. Violin is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology, Cardiology and Cardiovascular Medicine, Pharmacology and Physiology, having authored 53 papers that have together received 9.5k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (42 papers), Neuropeptides and Animal Physiology (27 papers), Protein Kinase Regulation and GTPase Signaling (9 papers), Cardiac electrophysiology and arrhythmias (6 papers), Renin-Angiotensin System Studies (6 papers), Pharmacological Receptor Mechanisms and Effects (5 papers), Computational Drug Discovery Methods (4 papers) and Nitric Oxide and Endothelin Effects (3 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (4.0k citations), Molecular Biology (7.6k citations), Biophysics (606 citations), Cell Biology (879 citations) and Cardiology and Cardiovascular Medicine (1.1k citations). Jonathan D. Violin has collaborated with scholars based in United States, Italy and Netherlands. Frequent co-authors include Robert J. Lefkowitz, Alexandra C. Newton, Roger Y. Tsien, David A. Zacharias, Erin J. Whalen, Scott M. DeWire, Michael W. Lark, David G. Soergel, David H. Rominger and Howard A. Rockman. Their work appears in journals such as Journal of Biological Chemistry, Proceedings of the National Academy of Sciences, Molecular Pharmacology, Journal of Pharmacology and Experimental Therapeutics and Journal of Clinical Investigation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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