Zhihong Lai

3.8k total citations
36 papers, 2.5k citations indexed

About

Zhihong Lai is a scholar working on Molecular Biology, Oncology and Cell Biology. According to data from OpenAlex, Zhihong Lai has authored 36 papers receiving a total of 2.5k indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Molecular Biology, 12 papers in Oncology and 8 papers in Cell Biology. Recurrent topics in Zhihong Lai's work include Cancer-related Molecular Pathways (9 papers), Amyloidosis: Diagnosis, Treatment, Outcomes (7 papers) and Microtubule and mitosis dynamics (6 papers). Zhihong Lai is often cited by papers focused on Cancer-related Molecular Pathways (9 papers), Amyloidosis: Diagnosis, Treatment, Outcomes (7 papers) and Microtubule and mitosis dynamics (6 papers). Zhihong Lai collaborates with scholars based in United States, United Kingdom and Hungary. Zhihong Lai's co-authors include Jeffery W. Kelly, Wilfredo Colón, Hilal A. Lashuel, Greta J. Miroy, Robert A. Copeland, Candace Strang, Scott Peterson, Kurt R. Auger, Jingsong Yang and Sandra L. McCutchen and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Molecular Biology.

In The Last Decade

Zhihong Lai

33 papers receiving 2.5k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Zhihong Lai United States	23	2.1k	718	635	631	205	36	2.5k
Mark R. Wardell United States	24	1.7k 0.8×	360 0.5×	552 0.9×	463 0.7×	148 0.7×	36	3.3k
Jannik N. Andersen United States	22	3.1k 1.5×	575 0.8×	202 0.3×	236 0.4×	92 0.4×	33	3.8k
P. Patrizia Mangione Italy	30	2.5k 1.2×	352 0.5×	1.4k 2.2×	309 0.5×	349 1.7×	72	3.0k
Marietta L. Harrison United States	32	2.0k 1.0×	428 0.6×	658 1.0×	468 0.7×	71 0.3×	70	3.8k
S. Terzyan United States	25	1.1k 0.5×	256 0.4×	486 0.8×	349 0.6×	226 1.1×	53	2.2k
Monica Stoppini Italy	31	2.5k 1.2×	235 0.3×	1.3k 2.1×	341 0.5×	371 1.8×	79	3.0k
Mark R. Hurle United States	22	1.6k 0.8×	349 0.5×	444 0.7×	255 0.4×	284 1.4×	32	2.1k
Rahul Das India	22	1.8k 0.9×	642 0.9×	146 0.2×	215 0.3×	191 0.9×	46	2.5k
Francesca Zappacosta United States	24	1.5k 0.7×	450 0.6×	104 0.2×	320 0.5×	73 0.4×	45	2.2k
Matthew F. Calabrese United States	14	1.6k 0.8×	470 0.7×	294 0.5×	161 0.3×	70 0.3×	20	1.9k

Countries citing papers authored by Zhihong Lai

Since Specialization

Citations

This map shows the geographic impact of Zhihong Lai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Zhihong Lai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Zhihong Lai more than expected).

Fields of papers citing papers by Zhihong Lai

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Zhihong Lai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Zhihong Lai. The network helps show where Zhihong Lai may publish in the future.

Co-authorship network of co-authors of Zhihong Lai

This figure shows the co-authorship network connecting the top 25 collaborators of Zhihong Lai. A scholar is included among the top collaborators of Zhihong Lai based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Zhihong Lai. Zhihong Lai is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Fuxench, Zelma C. Chiesa, et al.. (2025). Ruxolitinib cream monotherapy for facial and/or neck atopic dermatitis: results from a decentralized, randomized phase 2 clinical trial. Journal of Dermatological Treatment. 36(1). 2480744–2480744.

Zirwas, Matthew, et al.. (2025). Efficacy and safety of ruxolitinib cream for the treatment of moderate to severe chronic hand eczema: Results from a 16-week, multicenter, randomized, double-blind study. Journal of the American Academy of Dermatology. 94(1). 32–40.

Zirwas, Matthew, et al.. (2024). Efficacy and Safety of Ruxolitinib Cream for the Treatment of Moderate to Severe Chronic Hand Eczema: Top-Line Results From a 16-Week, Multicenter, Randomized, Double-Blind Study. SKIN The Journal of Cutaneous Medicine. 8(6). s500–s500.

Ma, Jianhong, John D. Martin, Yu Xue, et al.. (2010). C-terminal region of USP7/HAUSP is critical for deubiquitination activity and contains a second mdm2/p53 binding site. Archives of Biochemistry and Biophysics. 503(2). 207–212. 61 indexed citations

Yang, Jingsong, Robert A. Copeland, & Zhihong Lai. (2009). Defining Balanced Conditions for Inhibitor Screening Assays That Target Bisubstrate Enzymes. SLAS DISCOVERY. 14(2). 111–120. 49 indexed citations

Hardwicke, Mary Ann, Catherine A. Oleykowski, Ramona Plant, et al.. (2009). GSK1070916, a potent Aurora B/C kinase inhibitor with broad antitumor activity in tissue culture cells and human tumor xenograft models. Molecular Cancer Therapeutics. 8(7). 1808–1817. 89 indexed citations

Lin, Hong, Dennis S. Yamashita, Jin Zeng, et al.. (2009). 2,3,5-Trisubstituted pyridines as selective AKT inhibitors—Part I: Substitution at 2-position of the core pyridine for ROCK1 selectivity. Bioorganic & Medicinal Chemistry Letters. 20(2). 673–678. 11 indexed citations

Zhao, Baoguang, Angela Smallwood, Jingsong Yang, et al.. (2008). Modulation of kinase‐inhibitor interactions by auxiliary protein binding: Crystallography studies on Aurora A interactions with VX‐680 and with TPX2. Protein Science. 17(10). 1791–1797. 73 indexed citations

Colón, Wilfredo, Zhihong Lai, Sandra L. McCutchen, et al.. (2007). FAP Mutations Destabilize Transthyretin Facilitating Conformational Changes Required for Amyloid Formation. Novartis Foundation symposium. 199. 228–242. 18 indexed citations

10.

Fernandes, Christine, Kang Yan, Hong Zhang, et al.. (2006). A biochemical rationale for the anticancer effects of Hsp90 inhibitors: Slow, tight binding inhibition by geldanamycin and its analogues. Proceedings of the National Academy of Sciences. 103(20). 7625–7630. 92 indexed citations

11.

Huang, Jianzhong, Glenn S. Van Aller, Amy Taylor, et al.. (2006). Phylogenomic and Biochemical Characterization of ThreeLegionella pneumophilaPolypeptide Deformylases. Journal of Bacteriology. 188(14). 5249–5257. 8 indexed citations

12.

Auger, Kurt R., Robert A. Copeland, & Zhihong Lai. (2005). Quantitative Assays of Mdm2 Ubiquitin Ligase Activity and Other Ubiquitin‐Utilizing Enzymes for Inhibitor Discovery. Methods in enzymology on CD-ROM/Methods in enzymology. 399. 701–717. 5 indexed citations

13.

Kornacker, M. G., Zhihong Lai, Mark R. Witmer, et al.. (2005). An Inhibitor Binding Pocket Distinct from the Catalytic Active Site on Human β-APP Cleaving Enzyme. Biochemistry. 44(34). 11567–11573. 39 indexed citations

14.

Rusnak, David W., Zhihong Lai, Timothy J. Lansing, et al.. (2004). A simple method for predicting serum protein binding of compounds from IC 50 shift analysis for in vitro assays. Bioorganic & Medicinal Chemistry Letters. 14(9). 2309–2312. 12 indexed citations

15.

Lai, Zhihong, Melody Diamond, Young B. Kim, et al.. (2001). Human mdm2 Mediates Multiple Mono-ubiquitination of p53 by a Mechanism Requiring Enzyme Isomerization. Journal of Biological Chemistry. 276(33). 31357–31367. 128 indexed citations

16.

Lai, Zhihong, Kurt R. Auger, Jianhong Ma, et al.. (2000). Steady-State Kinetic Analysis of Human Ubiquitin-Activating Enzyme (E1) Using a Fluorescently Labeled Ubiquitin Substrate. Journal of Protein Chemistry. 19(6). 489–498. 21 indexed citations

17.

Lai, Zhihong, Deborah A. Freedman, Arnold J. Levine, & George McLendon. (1998). Metal and RNA Binding Properties of the hdm2 RING Finger Domain. Biochemistry. 37(48). 17005–17015. 40 indexed citations

18.

Lashuel, Hilal A., Zhihong Lai, & Jeffery W. Kelly. (1998). Characterization of the Transthyretin Acid Denaturation Pathways by Analytical Ultracentrifugation: Implications for Wild-Type, V30M, and L55P Amyloid Fibril Formation. Biochemistry. 37(51). 17851–17864. 174 indexed citations

19.

Nettleton, Ewan J., Margaret Sunde, Zhihong Lai, et al.. (1998). Protein subunit interactions and structural integrity of amyloidogenic transthyretins: evidence from electrospray mass spectrometry. Journal of Molecular Biology. 281(3). 553–564. 152 indexed citations

20.

McCutchen, Sandra L., Zhihong Lai, Greta J. Miroy, Jeffery W. Kelly, & Wilfredo Colón. (1995). Comparison of Lethal and Nonlethal Transthyretin Variants and Their Relationship to Amyloid Disease. Biochemistry. 34(41). 13527–13536. 173 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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