Keith R. Hornberger

1.7k total citations · 2 hit papers
18 papers, 1.2k citations indexed

About

Keith R. Hornberger is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, Keith R. Hornberger has authored 18 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 13 papers in Molecular Biology, 10 papers in Organic Chemistry and 4 papers in Oncology. Recurrent topics in Keith R. Hornberger's work include Melanoma and MAPK Pathways (4 papers), Synthesis and biological activity (3 papers) and Protein Kinase Regulation and GTPase Signaling (3 papers). Keith R. Hornberger is often cited by papers focused on Melanoma and MAPK Pathways (4 papers), Synthesis and biological activity (3 papers) and Protein Kinase Regulation and GTPase Signaling (3 papers). Keith R. Hornberger collaborates with scholars based in United States, Netherlands and China. Keith R. Hornberger's co-authors include Deborah Chirnomas, Craig M. Crews, James L. Leighton, Christopher L. Hamblett, George M. Adjabeng, Alex G. Waterson, David Uehling, Robert A. Mook, Scott H. Dickerson and Alastair J. King and has published in prestigious journals such as Journal of the American Chemical Society, Journal of Medicinal Chemistry and Journal of Pharmacology and Experimental Therapeutics.

In The Last Decade

Keith R. Hornberger

18 papers receiving 1.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Protein degraders enter the clinic — a new approach to cancer therapy

2023 375 citations Deborah Chirnomas, Keith R. Hornberger et al. Nature Reviews Clinical Oncology profile →
Physicochemical Property Determinants of Oral Absorption for PROTAC Protein Degraders

2023 88 citations Keith R. Hornberger et al. Journal of Medicinal Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Keith R. Hornberger United States	15	805	405	371	89	88	18	1.2k
Tianbao Lu United States	20	569 0.7×	415 1.0×	332 0.9×	92 1.0×	99 1.1×	36	1.1k
David M. Ryckman United States	18	1.3k 1.6×	423 1.0×	413 1.1×	75 0.8×	82 0.9×	31	1.8k
Matthäus Getlik Germany	15	964 1.2×	324 0.8×	456 1.2×	107 1.2×	148 1.7×	18	1.3k
Qingjie Ding China	11	641 0.8×	313 0.8×	528 1.4×	60 0.7×	45 0.5×	21	1.1k
Michael K. Schwaebe United States	13	1.4k 1.7×	290 0.7×	294 0.8×	47 0.5×	39 0.4×	21	1.7k
Kanami Yamazaki Japan	17	892 1.1×	238 0.6×	334 0.9×	51 0.6×	74 0.8×	27	1.4k
Rooha Contractor United States	14	870 1.1×	214 0.5×	469 1.3×	92 1.0×	51 0.6×	24	1.3k
Angelo Aguilar United States	17	1.3k 1.6×	419 1.0×	699 1.9×	195 2.2×	99 1.1×	28	1.8k
Siavosh Mahboobi Germany	26	1.0k 1.3×	858 2.1×	369 1.0×	183 2.1×	45 0.5×	76	1.8k
Céline Cano United Kingdom	21	834 1.0×	369 0.9×	387 1.0×	39 0.4×	73 0.8×	54	1.3k

Countries citing papers authored by Keith R. Hornberger

Since Specialization

Citations

This map shows the geographic impact of Keith R. Hornberger's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Keith R. Hornberger with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Keith R. Hornberger more than expected).

Fields of papers citing papers by Keith R. Hornberger

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Keith R. Hornberger. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Keith R. Hornberger. The network helps show where Keith R. Hornberger may publish in the future.

Co-authorship network of co-authors of Keith R. Hornberger

This figure shows the co-authorship network connecting the top 25 collaborators of Keith R. Hornberger. A scholar is included among the top collaborators of Keith R. Hornberger based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Keith R. Hornberger. Keith R. Hornberger is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

Chirnomas, Deborah, Keith R. Hornberger, & Craig M. Crews. (2023). Protein degraders enter the clinic — a new approach to cancer therapy. Nature Reviews Clinical Oncology. 20(4). 265–278. 375 indexed citations breakdown →

Hornberger, Keith R., et al.. (2023). Physicochemical Property Determinants of Oral Absorption for PROTAC Protein Degraders. Journal of Medicinal Chemistry. 66(12). 8281–8287. 88 indexed citations breakdown →

Hornberger, Keith R., Xin Chen, Andrew P. Crew, et al.. (2013). Discovery of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1: Optimization of kinase selectivity and pharmacokinetics. Bioorganic & Medicinal Chemistry Letters. 23(16). 4511–4516. 23 indexed citations

Rheault, Tara, John Stellwagen, George M. Adjabeng, et al.. (2013). Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B-Raf-Driven Tumors. ACS Medicinal Chemistry Letters. 4(3). 358–362. 175 indexed citations

Xie, Wensheng, Brandon J. Turunen, William J. Zuercher, et al.. (2012). The Development of a High-Content Screening Binding Assay for the Smoothened Receptor. SLAS DISCOVERY. 17(7). 900–911. 4 indexed citations

Stellwagen, John, George M. Adjabeng, Marc R. Arnone, et al.. (2011). Development of potent B-RafV600E inhibitors containing an arylsulfonamide headgroup. Bioorganic & Medicinal Chemistry Letters. 21(15). 4436–4440. 22 indexed citations

Waterson, Alex G., Kimberly G. Petrov, Keith R. Hornberger, et al.. (2009). Synthesis and evaluation of aniline headgroups for alkynyl thienopyrimidine dual EGFR/ErbB-2 kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 19(5). 1332–1336. 33 indexed citations

Emmitte, Kyle A., C. Webb Andrews, Ramesh Bambal, et al.. (2009). Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding. Bioorganic & Medicinal Chemistry Letters. 19(6). 1694–1697. 54 indexed citations

Laquerre, Sylvie, Marc R. Arnone, Katherine G. Moss, et al.. (2009). Abstract B88: A selective Raf kinase inhibitor induces cell death and tumor regression of human cancer cell lines encoding B-RafV600E mutation. Molecular Cancer Therapeutics. 8(12_Supplement). B88–B88. 45 indexed citations

10.

Adjabeng, George M., et al.. (2009). Mild conditions for Pd-catalyzed conversion of aryl bromides to primary anilines using benzophenone imine. Tetrahedron Letters. 50(14). 1582–1585. 9 indexed citations

11.

Rominger, Cynthia M., Robert A. Copeland, Elizabeth A. Davenport, et al.. (2009). Evidence for Allosteric Interactions of Antagonist Binding to the Smoothened Receptor. Journal of Pharmacology and Experimental Therapeutics. 329(3). 995–1005. 52 indexed citations

12.

Waterson, Alex G., et al.. (2009). Room-Temperature Pd-Catalyzed Amidation of Aryl Bromides Using tert-Butyl Carbamate. The Journal of Organic Chemistry. 74(12). 4634–4637. 33 indexed citations

13.

Hubbard, Robert D., Scott H. Dickerson, Robert Griffin, et al.. (2008). Dual EGFR/ErbB-2 inhibitors from novel pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidines. Bioorganic & Medicinal Chemistry Letters. 18(21). 5738–5740. 29 indexed citations

14.

Hornberger, Keith R., et al.. (2008). Regioselective synthesis of benzimidazole thiophene inhibitors of polo-like kinase 1. Tetrahedron Letters. 49(44). 6348–6351. 25 indexed citations

15.

Hornberger, Keith R., George M. Adjabeng, Hamilton D. Dickson, & Ronda G. Davis‐Ward. (2006). A mild, one-pot synthesis of disubstituted benzimidazoles from 2-nitroanilines. Tetrahedron Letters. 47(30). 5359–5361. 35 indexed citations

16.

Dreher, Spencer D., Keith R. Hornberger, Stella T. Sarraf, & James L. Leighton. (2000). Yb(OTf)₃-Catalyzed Oxymercuration of Homoallylic Alcohol-Derived Hemiacetals and Hemiketals. Organic Letters. 2(20). 3197–3199. 13 indexed citations

17.

Hornberger, Keith R., Christopher L. Hamblett, & James L. Leighton. (2000). Total Synthesis of Leucascandrolide A. Journal of the American Chemical Society. 122(51). 12894–12895. 147 indexed citations

18.

Chenault, H. Keith, et al.. (1997). Synthetic Utility of Yeast Hexokinase. Substrate Specificity, Cofactor Regeneration, and Product Isolation. The Journal of Organic Chemistry. 62(2). 331–336. 31 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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