Dirk A. Heerding

3.1k citations

23 papers · 870 indexed · h-index 15

Co-authors: Elisabeth A. Minthorn Dennis T. Takata William F. Huffman Stephen Rittenhouse Rakesh Kumar Mark A. Seefeld William H. Miller Meagan B. Rouse
Topics: Click Chemistry and Applications (5 papers)PI3K/AKT/mTOR signaling in cancer (5 papers)Ubiquitin and proteasome pathways (4 papers)
Cited by: Organic Chemistry Molecular Medicine Cell Biology
Journals: Journal of the American Chemical Society PLoS ONE Journal of Molecular Biology
Partner nations: United States United Kingdom India

In The Last Decade

Dirk A. Heerding

23 papers receiving 844 citations

Peers

Countries citing papers authored by Dirk A. Heerding

Since Specialization

Citations

This map shows the geographic impact of Dirk A. Heerding's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dirk A. Heerding with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dirk A. Heerding more than expected).

Fields of papers citing papers by Dirk A. Heerding

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dirk A. Heerding. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dirk A. Heerding. The network helps show where Dirk A. Heerding may publish in the future.

Co-authorship network of co-authors of Dirk A. Heerding

This figure shows the co-authorship network connecting the top 25 collaborators of Dirk A. Heerding. A scholar is included among the top collaborators of Dirk A. Heerding based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Dirk A. Heerding. Dirk A. Heerding is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Design and synthesis of aminopyridine containing biaryls reducing c-MYC protein levels in cells 2023 ·Bioorganic & Medicinal Chemistry Letters ·Christina N. Di Marco,Lamont R. Terrell,Robert A. Sanchez,Lourdes Rueda,(unknown),(unknown),Charles F. McHugh,(unknown),Arthur Y. L. Shu,Xinrong Tian,Jesús R. Medina,Ralph A. Rivero,Roman Manetsch,Dirk A. Heerding,(unknown)	1
2	Abstract A044: The discovery of potent KAT6 inhibitors that demonstrate anti-tumor activity in preclinical models of ER+ breast cancer 2023 ·Molecular Cancer Therapeutics ·Gopinath S. Palanisamy,Venkateshappa Chandregowda,(unknown),(unknown),Brian R. Hearn,Girish Daginakatte,(unknown),Dodderi S. Samiulla,Kalisankar Bera,S. Sangeetha,Leena Khare,(unknown),Dirk A. Heerding,(unknown),Cyrus L. Harmon,Susanta Samajdar,Murali Ramachandra,David C. Myles	1
3	Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors 2022 ·Structure ·J.R. Horton,(unknown),Kristen Wong,Ren Ren,Lourdes Rueda,(unknown),Dirk A. Heerding,Michael T. McCabe,Melissa B. Pappalardi,Xing Zhang,Bryan W. King,Xiaodong Cheng	19
4	Structural Characterization of Dicyanopyridine Containing DNMT1-Selective, Non-Nucleoside Inhibitors 2022 ·SSRN Electronic Journal ·J.R. Horton,(unknown),Kristen Wong,Ren Ren,Lourdes Rueda,(unknown),Dirk A. Heerding,Michael T. McCabe,Melissa B. Pappalardi,Xing Zhang,Bryan W. King,Xiaodong Cheng	1
5	Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10 2017 ·Journal of Molecular Biology ·Wei Zhang,(unknown),Taras Makhnevych,Kelly Federowicz,(unknown),Li Liu,Satra Nim,Aiping Dong,Jingsong Yang,Yanjun Li,Dania Haddad,Andreas Ernst,Dirk A. Heerding,Yufeng Tong,Jason Moffat,Sachdev S. Sidhu	43
6	Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1α Endoribonuclease Activity 2015 ·Molecular Pharmacology ·N.O. Concha,Angela Smallwood,William G. Bonnette,Rachel D. Totoritis,Guofeng Zhang,Kelly Federowicz,Jingsong Yang,Hongwei Qi,Stephanie Chen,Nino Campobasso,Anthony E. Choudhry,(unknown),Karen A. Evans,(unknown),Sharon Sweitzer,Dirk A. Heerding,Carolyn A. Buser,Dai‐Shi Su,M. Phillip DeYoung	42
7	Discovery of Novel AKT Inhibitors with Enhanced Anti-Tumor Effects in Combination with the MEK Inhibitor 2014 ·PLoS ONE ·Melissa Dumble,Ming‐Chih Crouthamel,Shuyun Zhang,Michael D. Schaber,Dana S. Levy,Kimberly A. Robell,Qi Liu,David J. Figueroa,Elisabeth A. Minthorn,Mark A. Seefeld,Meagan B. Rouse,Sridhar K. Rabindran,Dirk A. Heerding,Rakesh Kumar	116
8	Aminofurazans as potent inhibitors of AKT kinase 2009 ·Bioorganic & Medicinal Chemistry Letters ·Meagan B. Rouse,Mark A. Seefeld,Jack D. Leber,(unknown),(unknown),William H. Miller,ShuYun Zhang,Elisabeth A. Minthorn,N.O. Concha,Anthony E. Choudhry,Michael D. Schaber,Dirk A. Heerding	33
9	2,3,5-Trisubstituted pyridines as selective AKT inhibitors—Part I: Substitution at 2-position of the core pyridine for ROCK1 selectivity 2009 ·Bioorganic & Medicinal Chemistry Letters ·Hong Lin,Dennis S. Yamashita,Jin Zeng,(unknown),Wenyong Wang,(unknown),Juan I. Luengo,Nelson Rhodes,Victoria B. Knick,Anthony E. Choudhry,Zhihong Lai,Elisabeth A. Minthorn,Susan L. Strum,Edgar R. Wood,P.A. Elkins,N.O. Concha,Dirk A. Heerding	11
10	Discovery of 5-pyrrolopyridinyl-2-thiophenecarboxamides as potent AKT kinase inhibitors 2009 ·Bioorganic & Medicinal Chemistry Letters ·Mark A. Seefeld,Meagan B. Rouse,(unknown),(unknown),Jizhou Wang,Dennis S. Yamashita,Juan I. Luengo,ShuYun Zhang,Elisabeth A. Minthorn,N.O. Concha,Dirk A. Heerding	21
11	2,3,5-Trisubstituted pyridines as selective AKT inhibitors. Part II: Improved drug-like properties and kinase selectivity from azaindazoles 2009 ·Bioorganic & Medicinal Chemistry Letters ·Hong Lin,Dennis S. Yamashita,Jin Zeng,(unknown),Sharad K. Verma,Juan I. Luengo,Nelson Rhodes,Shuyun Zhang,Kimberly A. Robell,Anthony E. Choudhry,Zhihong Lai,Rakesh Kumar,Elisabeth A. Minthorn,Kristin K. Brown,Dirk A. Heerding	8
12	New benzimidazoles as thrombopoietin receptor agonists 2006 ·Bioorganic & Medicinal Chemistry Letters ·Igor G. Safonov,Dirk A. Heerding,Richard M. Keenan,Alan T. Price,Connie L. Erickson‐Miller,Christopher B. Hopson,(unknown),Kenneth A. Lord,Peter Tapley	37
13	New Benzylidenethiazolidinediones as Antibacterial Agents 2003 ·Bioorganic & Medicinal Chemistry Letters ·Dirk A. Heerding,(unknown),Tammy J. Clark,David Holmes,Stephen Rittenhouse,Dennis T. Takata,Joseph W. Venslavsky	47
14	Discovery of Aminopyridine-Based Inhibitors of Bacterial Enoyl-ACP Reductase (FabI) 2002 ·Journal of Medicinal Chemistry ·William H. Miller,Mark A. Seefeld,Kenneth A. Newlander,Irene N. Uzinskas,(unknown),Dirk A. Heerding,Catherine Yuan,Martha S. Head,David Payne,Stephen Rittenhouse,Terrance Moore,S. Pearson,Valerie Berry,Walter E. DeWolf,Paul M. Keller,(unknown),Xiayang Qiu,Cheryl A. Janson,William F. Huffman	90
15	1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI) 2001 ·Bioorganic & Medicinal Chemistry Letters ·Dirk A. Heerding,George Chan,Walter E. DeWolf,Andrew Fosberry,Cheryl A. Janson,Deborah D. Jaworski,Edward C. McManus,William H. Miller,Terrance Moore,David Payne,Xiayang Qiu,Stephen Rittenhouse,(unknown),Ward W. Smith,Dennis T. Takata,(unknown),Catherine Yuan,William F. Huffman	110
16	Novel peptidomimetic hematoregulatory compounds 2000 ·Bioorganic & Medicinal Chemistry Letters ·Dirk A. Heerding,(unknown),(unknown),Joelle L. Burgess,James F. Callahan,William F. Huffman,Andrew G. King,(unknown),(unknown),Louis M. Pelus,(unknown),Pradip K. Bhatnagar	2
17	Development of a Pharmacophore Model for a Novel Hematoregulatory Peptide 1996 ·Journal of the American Chemical Society ·Pradip K. Bhatnagar,(unknown),James F. Callahan,Dirk A. Heerding,William F. Huffman,Andrew G. King,(unknown),Louis M. Pelus,(unknown)	9
18	Stereoselective synthesis of (2R)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylaminohex-4-ynoic Acid 1996 ·Tetrahedron Asymmetry ·Dirk A. Heerding,Pradip K. Bhatnagar,Michael Hartmann,(unknown),(unknown)	2
19	Simple method for controlling stereoselection in Mannich cyclization reactions of aldehydes 1993 ·The Journal of Organic Chemistry ·Dirk A. Heerding,Chang Yong Hong,Noriyuki Kado,Gary C. Look,Larry E. Overman	19
20	Studies on the synthesis of (-)-neplanocin A. Homochiral preparation of a key cyclopentanoid intermediate 1988 ·The Journal of Organic Chemistry ·Donald R. Deardorff,Soroosh Shambayati,David C. Myles,Dirk A. Heerding	27

About Dirk A. Heerding

Dirk A. Heerding is a scholar working on Organic Chemistry, Microbiology and Molecular Biology, having authored 23 papers that have together received 870 indexed citations. Recurring topics across this work include Click Chemistry and Applications (5 papers), PI3K/AKT/mTOR signaling in cancer (5 papers) and Ubiquitin and proteasome pathways (4 papers). The work is most often cited by research in Organic Chemistry (358 citations), Molecular Medicine (53 citations) and Cell Biology (171 citations). Dirk A. Heerding has collaborated with scholars based in United States, United Kingdom and India. Frequent co-authors include Elisabeth A. Minthorn, Dennis T. Takata, William F. Huffman, Stephen Rittenhouse, Rakesh Kumar, Mark A. Seefeld, William H. Miller, Meagan B. Rouse, Jesús R. Medina and Jeffrey M. Axten. Their work appears in journals such as Journal of the American Chemical Society, PLoS ONE and Journal of Molecular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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